Works matching IS 10966080 AND DT 2019 AND VI 170 AND IP 2

Results: 28

CRISPR/Cas9 Whole-Genome Screen Identifies Genes Required for Aryl Hydrocarbon Receptor-Dependent Induction of Functional CYP1A1.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 310, doi. 10.1093/toxsci/kfz111

By:

Sundberg, Christopher D;
Hankinson, Oliver

Publication type:

Article

Cancer Chemoprevention: Preclinical In Vivo Alternate Dosing Strategies to Reduce Drug Toxicities.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 251, doi. 10.1093/toxsci/kfz104

By:

Mohammed, Altaf;
Fox, Jennifer T;
Miller, Mark Steven

Publication type:

Article

Blockade of the NLRP3/Caspase-1 Axis Ameliorates Airway Neutrophilic Inflammation in a Toluene Diisocyanate-Induced Murine Asthma Model.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 462, doi. 10.1093/toxsci/kfz099

By:

Chen, Shuyu;
Yao, Lihong;
Huang, Peikai;
He, Qiaoling;
Guan, Hongbing;
Luo, Yiqin;
Zou, Zehong;
Wei, Shushan;
Peng, Guoyou;
Yan, Jie;
Chen, Rongchang;
Zhang, Qingling;
Tao, Ailin

Publication type:

Article

Bisphenol A Promotes the Invasive and Metastatic Potential of Ductal Carcinoma In Situ and Protumorigenic Polarization of Macrophages.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 283, doi. 10.1093/toxsci/kfz119

By:

Kim, Hyelim;
Kim, Hoe Suk;
Piao, Yin Ji;
Moon, Woo Kyung

Publication type:

Article

Assessing Drug-Induced Long QT and Proarrhythmic Risk Using Human Stem-Cell-Derived Cardiomyocytes in a Ca 2+ Imaging Assay: Evaluation of 28 CiPA Compounds at Three Test Sites.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 345, doi. 10.1093/toxsci/kfz102

By:

Lu, Hua Rong;
Zeng, Haoyu;
Kettenhofen, Ralf;
Guo, Liang;
Kopljar, Ivan;
Ammel, Karel van;
Tekle, Fetene;
Teisman, Ard;
Zhai, Jin;
Clouse, Holly;
Pierson, Jennifer;
Furniss, Michael;
Lagrutta, Armando;
Sannajust, Frederick;
Gallacher, David J

Publication type:

Article

Apoptosis Resistance in Fibroblasts Precedes Progressive Scarring in Pulmonary Fibrosis and Is Partially Mediated by Toll-Like Receptor 4 Activation.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 489, doi. 10.1093/toxsci/kfz103

By:

Hanson, Kelly M;
Hernady, Eric B;
Reed, Christina K;
Johnston, Carl J;
Groves, Angela M;
Finkelstein, Jacob N

Publication type:

Article

Aneugen Molecular Mechanism Assay: Proof-of-Concept With 27 Reference Chemicals.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 382, doi. 10.1093/toxsci/kfz123

By:

Bernacki, Derek T;
Bryce, Steven M;
Bemis, Jeffrey C;
Dertinger, Stephen D

Publication type:

Article

TSPO PET Using [ 18 F]PBR111 Reveals Persistent Neuroinflammation Following Acute Diisopropylfluorophosphate Intoxication in the Rat.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 330, doi. 10.1093/toxsci/kfz096

By:

Hobson, Brad A;
Rowland, Douglas J;
Sisó, Sílvia;
Guignet, Michelle A;
Harmany, Zachary T;
Bandara, Suren B;
Saito, Naomi;
Harvey, Danielle J;
Bruun, Donald A;
Garbow, Joel R;
Chaudhari, Abhijit J;
Lein, Pamela J

Publication type:

Article

TGFβ1 Receptor Antagonist GW788388 Reduces JNK Activation and Protects Against Acetaminophen Hepatotoxicity in Mice.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 549, doi. 10.1093/toxsci/kfz122

By:

McMillin, Matthew;
Grant, Stephanie;
Frampton, Gabriel;
Petrescu, Anca D;
Williams, Elaina;
Jefferson, Brandi;
DeMorrow, Sharon

Publication type:

Article

Rotenone and Parkinson's Disease: Reduced Sensitivity in Females.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 562, doi. 10.1093/toxsci/kfz126

By:

Goldman, Samuel M;
Tanner, Caroline M

Publication type:

Article

Response to Rotenone and Parkinson's Disease; Reduced Sensitivity in Females.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 563, doi. 10.1093/toxsci/kfz127

By:

Miranda, Briana R De;
Greenamyre, John Timothy

Publication type:

Article

Quizalofop-p-Ethyl Induces Adipogenesis in 3T3-L1 Adipocytes.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 452, doi. 10.1093/toxsci/kfz097

By:

Biserni, Martina;
Mesnage, Robin;
Ferro, Raquel;
Wozniak, Eva;
Xenakis, Theodoros;
Mein, Charles A;
Antoniou, Michael N

Publication type:

Article

Prenatal Exposure to Bisphenol A, E, and S Induces Transgenerational Effects on Female Reproductive Functions in Mice.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 320, doi. 10.1093/toxsci/kfz124

By:

Shi, Mingxin;
Whorton, Allison E;
Sekulovski, Nikola;
MacLean, James A;
Hayashi, Kanako

Publication type:

Article

Predicting Human Infection Risk: Do Rodent Host Resistance Models Add Value?

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 260, doi. 10.1093/toxsci/kfz116

By:

Wu, Kai Connie;
Zhong, Yu;
Maher, Jonathan

Publication type:

Article

Parental PM 2.5 Exposure-Promoted Development of Metabolic Syndrome in Offspring Is Associated With the Changes of Immune Microenvironment.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 415, doi. 10.1093/toxsci/kfz109

By:

Zhang, Jia;
Zeng, Xuejiao;
Du, Xihao;
Pan, Kun;
Song, Liying;
Song, Weimin;
Xie, Yuquan;
Zhao, Jinzhuo

Publication type:

Article

Novel Open Access Web Portal for Integrating Mechanistic and Toxicogenomic Study Results.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 296, doi. 10.1093/toxsci/kfz101

By:

Sutherland, Jeffrey J;
Stevens, James L;
Johnson, Kamin;
Elango, Navin;
Webster, Yue W;
Mills, Bradley J;
Robertson, Daniel H

Publication type:

Article

Acetaminophen Responsive miR-19b Modulates SIRT1/Nrf2 Signaling Pathway in Drug-Induced Hepatotoxicity.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 476, doi. 10.1093/toxsci/kfz095

By:

Liu, Xing;
Zhao, Hongqian;
Luo, Chunyan;
Du, Debin;
Huang, Jinlong;
Ming, Quan;
Jin, Fen;
Wang, Decheng;
Huang, Weifeng

Publication type:

Article

Mixed Vehicle Emissions Induces Angiotensin II and Cerebral Microvascular Angiotensin Receptor Expression in C57Bl/6 Mice and Promotes Alterations in Integrity in a Blood-Brain Barrier Coculture Model.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 525, doi. 10.1093/toxsci/kfz121

By:

Suwannasual, Usa;
Lucero, JoAnn;
Davis, Griffith;
McDonald, Jacob D;
Lund, Amie K

Publication type:

Article

Metabolism and Lung Toxicity of Inhaled Naphthalene: Effects of Postnatal Age and Sex.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 536, doi. 10.1093/toxsci/kfz100

By:

Carratt, Sarah A;
Kovalchuk, Nataliia;
Ding, Xinxin;
Winkle, Laura S Van

Publication type:

Article

Intracellular Demethylation of Methylmercury to Inorganic Mercury by Organomercurial Lyase (MerB) Strengthens Cytotoxicity.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 438, doi. 10.1093/toxsci/kfz094

By:

Takanezawa, Yasukazu;
Nakamura, Ryosuke;
Matsuda, Haruki;
Yagi, Tomomi;
Egawa, Zen;
Sone, Yuka;
Uraguchi, Shimpei;
Adachi, Tatsumi;
Kiyono, Masako

Publication type:

Article

Interleukin 33 Expression Induced by Aryl Hydrocarbon Receptor in Macrophages.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 404, doi. 10.1093/toxsci/kfz114

By:

Ishihara, Yasuhiro;
Haarmann-Stemmann, Thomas;
Kado, Norman Y;
Vogel, Christoph F A

Publication type:

Article

Interactions of Dichlorodiphenyltrichloroethane (DDT) and Dichlorodiphenyldichloroethylene (DDE) With Skeletal Muscle Ryanodine Receptor Type 1.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 509, doi. 10.1093/toxsci/kfz120

By:

Truong, Kim M;
Cherednichenko, Gennady;
Pessah, Isaac N

Publication type:

Article

Histopathological and Molecular Signatures of a Mouse Model of Acute-on-Chronic Alcoholic Liver Injury Demonstrate Concordance With Human Alcoholic Hepatitis.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 427, doi. 10.1093/toxsci/kfy292

By:

Furuya, Shinji;
Cichocki, Joseph A;
Konganti, Kranti;
Dreval, Kostiantyn;
Uehara, Takeki;
Katou, Yuuki;
Fukushima, Hisataka;
Kono, Hiroshi;
Pogribny, Igor P;
Argemi, Josepmaria;
Bataller, Ramon;
Rusyn, Ivan

Publication type:

Article

Hepatocyte-Derived Exosomes Promote Liver Immune Tolerance: Possible Implications for Idiosyncratic Drug-Induced Liver Injury.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 499, doi. 10.1093/toxsci/kfz112

By:

Holman, Natalie S;
Church, Rachel J;
Nautiyal, Manisha;
Rose, Kelly A;
Thacker, Sarah E;
Otieno, Monicah A;
Wolf, Kristina K;
LeCluyse, Edward;
Watkins, Paul B;
Mosedale, Merrie

Publication type:

Article

Gene Expression and DNA Methylation Alterations in the Glycine N-Methyltransferase Gene in Diet-Induced Nonalcoholic Fatty Liver Disease-Associated Carcinogenesis.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 273, doi. 10.1093/toxsci/kfz110

By:

Borowa-Mazgaj, Barbara;
Conti, Aline de;
Tryndyak, Volodymyr;
Steward, Colleen R;
Jimenez, Leandro;
Melnyk, Stepan;
Seneshaw, Mulugeta;
Mirshahi, Faridodin;
Rusyn, Ivan;
Beland, Frederick A;
Sanyal, Arun J;
Pogribny, Igor P

Publication type:

Article

Enhanced Quality Metrics for Assessing RNA Derived From Archival Formalin-Fixed Paraffin-Embedded Tissue Samples.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 357, doi. 10.1093/toxsci/kfz113

By:

Wehmas, Leah C;
Wood, Charles E;
Chorley, Brian N;
Yauk, Carole L;
Nelson, Gail M;
Hester, Susan D

Publication type:

Article

Differential Sensitivity to In Vitro Inhibition of Cytochrome P450 Aromatase (CYP19) Activity Among 18 Freshwater Fishes.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 394, doi. 10.1093/toxsci/kfz115

By:

Doering, Jon A;
Villeneuve, Daniel L;
Fay, Kellie A;
Randolph, Eric C;
Jensen, Kathleen M;
Kahl, Michael D;
LaLone, Carlie A;
Ankley, Gerald T

Publication type:

Article

Validation of the GARD™skin Assay for Assessment of Chemical Skin Sensitizers: Ring Trial Results of Predictive Performance and Reproducibility.

Published in:

Toxicological Sciences, 2019, v. 170, n. 2, p. 374, doi. 10.1093/toxsci/kfz108

By:

Johansson, Henrik;
Gradin, Robin;
Johansson, Angelica;
Adriaens, Els;
Edwards, Amber;
Zuckerstätter, Veronika;
Jerre, Anders;
Burleson, Florence;
Gehrke, Helge;
Roggen, Erwin L

Publication type:

Article