Works matching IS 10966080 AND DT 2015 AND VI 147 AND IP 2

Results: 31

Inhibition of Voltage-Gated Calcium Channels After Subchronic and Repeated Exposure of PC12 Cells to Different Classes of Insecticides.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 607, doi. 10.1093/toxsci/kfv154

By:

Meijer, Marieke;
Brandsema, Joske A. R.;
Nieuwenhuis, Desirée;
Wijnolts, Fiona M. J.;
Dingemans, Milou M. L.;
Westerink, Remco H. S.

Publication type:

Article

Chlorpyrifos Induces MLL Translocations Through Caspase 3-Dependent Genomic Instability and Topoisomerase II Inhibition in Human Fetal Liver Hematopoietic Stem Cells.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 588, doi. 10.1093/toxsci/kfv153

By:

Chengquan Lu;
Xiaohui Liu;
Chang Liu;
Jian Wang;
Chunna Li;
Qi Liu;
Yachen Li;
Shuangyue Li;
Shu Sun;
Jinsong Yan;
Jing Shao

Publication type:

Article

Cellular accumulation and toxic effects of bile acids in cyclosporine A-treated HepaRG hepatocytes.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 573, doi. 10.1093/toxsci/kfv155

By:

Sharanek, Ahmad;
Burban, Audrey;
Humbert, Lydie;
Azzi, Pamela Bachour-El;
Felix-Gomes, Neuza;
Rainteau, Dominique;
Guillouzo, Andre

Publication type:

Article

Potential Adverse Effects of Prolonged Sevoflurane Exposure on Developing Monkey Brain: From Abnormal Lipid Metabolism to Neuronal Damage.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 562, doi. 10.1093/toxsci/kfv150

By:

Fang Liu;
Rainosek, Shuo W.;
Frisch-Daiello, Jessica L.;
Patterson, Tucker A.;
Paule, Merle G.;
Slikker Jr., William;
Cheng Wang;
Xianlin Han

Publication type:

Article

Mechanistic Investigation of Toxaphene Induced Mouse Liver Tumors.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 549, doi. 10.1093/toxsci/kfv151

By:

Zemin Wang;
Neal, Barbara H.;
Lamb, James C.;
Klaunig, James E.

Publication type:

Article

Endogenous 2-Arachidonoylglycerol Alleviates Cyclooxygenases-2 Elevation-Mediated Neuronal Injury From SO<sub>2</sub> Inhalation via PPAR<sub>γ</sub> Pathway.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 535, doi. 10.1093/toxsci/kfv147

By:

Ben Li;
Minjun Chen;
Lin Guo;
Yang Yun;
Guangke Li;
Nan Sang

Publication type:

Article

Low-Dose Cadmium Causes Metabolic and Genetic Dysregulation Associated With Fatty Liver Disease in Mice.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 524, doi. 10.1093/toxsci/kfv149

By:

Young-Mi Go;
Sutliff, Roy L.;
Chandler, Joshua D.;
Khalidur, Rahman;
Bum-Yong Kang;
Anania, Frank A.;
Orr, Michael;
Li Hao;
Fowler, Bruce A.;
Jones, Dean P.

Publication type:

Article

Activation of the Endoperoxide Ascaridole Modulates Its Sensitizing Capacity.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 515, doi. 10.1093/toxsci/kfv148

By:

Krutz, Nora L.;
Hennen, Jennifer;
Korb, Corinna;
Schellenberger, Mario T.;
Gerberick, G. Frank;
Blömeke, Brunhilde

Publication type:

Article

Setting Clinical Exposure Levels of Concern for Drug-Induced Liver Injury (DILI) Using Mechanistic in vitro Assays.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 500, doi. 10.1093/toxsci/kfv152

By:

Shah, Falgun;
Leung, Louis;
Barton, Hugh A.;
Will, Yvonne;
Rodrigues, A. David;
Greene, Nigel;
Aleo, Michael D.

Publication type:

Article

Chronic Exposure to Particulate Chromate Induces Premature Centrosome Separation and Centriole Disengagement in Human Lung Cells.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 490, doi. 10.1093/toxsci/kfv146

By:

Julieta Martino;
Holmes, Amie L.;
Hong Xie;
Wise, Sandra S.;
Wise Sr., John Pierce

Publication type:

Article

Ethanol Attenuates Histiotrophic Nutrition Pathways and Alters the Intracellular Redox Environment and Thiol Proteome during Rat Organogenesis.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 475, doi. 10.1093/toxsci/kfv145

By:

Jilek, Joseph L.;
Sant, Karilyn E.;
Cho, Katherine H.;
Reed, Matthew S.;
Pohl, Jan;
Hansen, Jason M.;
Harris, Craig

Publication type:

Article

Glutathione Depletion Accelerates Cigarette Smoke-Induced Inflammation and Airspace Enlargement.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 466, doi. 10.1093/toxsci/kfv143

By:

Gould, Neal S.;
Min, Elysia;
Jie Huang;
Hong Wei Chu;
Good, Jim;
Martin, Richard J.;
Day, Brian J.

Publication type:

Article

Determination of Toxic Activities in Bothrops spp. Snake Venoms Using Animal-Free Approaches: Correlation Between In Vitro Versus In Vivo Assays.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 458, doi. 10.1093/toxsci/kfv140

By:

de Souza, Letícia Lopes;
Stransky, Stephanie;
Guerra-Duarte, Clara;
Flor-Sá, Ana;
Schneider, Francisco Santos;
Kalapothakis, Evanguedes;
Chávez-Olórtegui, Carlos

Publication type:

Article

Cell-Based High-Throughput Screening for Aromatase Inhibitors in the Tox21 10K Library.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 446, doi. 10.1093/toxsci/kfv141

By:

Shiuan Chen;
Jui-Hua Hsieh;
Ruili Huang;
Srilatha Sakamuru;
Li-Yu Hsin;
Menghang Xia;
Shockley, Keith R.;
Auerbach, Scott;
Noriko Kanaya;
Hannah Lu;
Svoboda, Daniel;
Witt, Kristine L.;
Merrick, B. Alex;
Teng, Christina T.;
Tice, Raymond R.

Publication type:

Article

Pyrene is a Novel Constitutive Androstane Receptor (CAR) Activator and Causes Hepatotoxicity by CAR.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 436, doi. 10.1093/toxsci/kfv142

By:

Xiao-Jie Zhang;
Zhe Shi;
Jing-Xi Lyv;
Xuyan He;
Englert, Neal A.;
Shu-Yun Zhang

Publication type:

Article

Ah Receptor Signaling Controls the Expression of Cardiac Development and Homeostasis Genes.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 425, doi. 10.1093/toxsci/kfv138

By:

Carreira, Vinicius S.;
Yunxia Fan;
Qing Wang;
Xiang Zhang;
Hisaka Kurita;
Ko, Chia-I.;
Naticchioni, Mindi;
Min Jiang;
Koch, Sheryl;
Medvedovic, Mario;
Ying Xia;
Rubinstein, Jack;
Puga, Alvaro

Publication type:

Article

Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 412, doi. 10.1093/toxsci/kfv136

By:

Sison-Young, Rowena L. C.;
Mitsa, Dimitra;
Jenkins, Rosalind E.;
Mottram, David;
Alexandre, Eliane;
Richert, Lysiane;
Aerts, Hélène;
Weaver, Richard J.;
Jones, Robert P.;
Johann, Esther;
Hewitt, Philip G.;
Ingelman-Sundberg, Magnus;
Goldring, Christopher E. P.;
Kitteringham, Neil R.;
Park, B. Kevin

Publication type:

Article

Ligand-Specific Transcriptional Mechanisms Underlie Aryl Hydrocarbon Receptor-Mediated Developmental Toxicity of Oxygenated PAHs.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 397, doi. 10.1093/toxsci/kfv139

By:

Goodale, B. C.;
La Du, J.;
Tilton, S. C.;
Sullivan, C. M.;
Bisson, W. H.;
Waters, K. M.;
Tanguay, R. L.

Publication type:

Article

Acute Toxicity Prediction in Multiple Species by Leveraging Mechanistic ToxCast Mitochondrial Inhibition Data and Simulation of Oral Bioavailability.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 386, doi. 10.1093/toxsci/kfv135

By:

Bhhatarai, Barun;
Wilson, Daniel M.;
Bartels, Michael J.;
Chaudhuri, Shubhra;
Price, Paul S.;
Carney, Edward W.

Publication type:

Article

Systems Biology Reveals Cigarette Smoke-Induced Concentration-Dependent Direct and Indirect Mechanisms That Promote Monocyte-Endothelial Cell Adhesion.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 370, doi. 10.1093/toxsci/kfv137

By:

Poussin, Carine;
Laurent, Alexandra;
Peitsch, Manuel C.;
Hoeng, Julia;
De Leon, Hector

Publication type:

Article

Uridine Diphosphate-Glucuronosyltransferase (UGT) Xenobiotic Metabolizing Activity and Genetic Evolution in Pinniped Species.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 360, doi. 10.1093/toxsci/kfv144

By:

Mayu Kakehi;
Yoshinori Ikenaka;
Nakayama, Shouta M. M.;
Kawai, Yusuke K.;
Watanabe, Kensuke P.;
Hazuki Mizukawa;
Kei Nomiyama;
Shinsuke Tanabe;
Mayumi Ishizuka

Publication type:

Article

High-Dose Vitamin C Injection to Cancer Patients May Promote Thrombosis Through Procoagulant Activation of Erythrocytes.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 350, doi. 10.1093/toxsci/kfv133

By:

Keunyoung Kim;
Ok-Nam Bae;
Sung-Hee Koh;
Seojin Kang;
Kyung-Min Lim;
Ji-Yoon Noh;
Sue Shin;
Inho Kim;
Jin-Ho Chung

Publication type:

Article

The Contribution of Peroxisome Proliferator-Activated Receptor Alpha to the Relationship Between Toxicokinetics and Toxicodynamics of Trichloroethylene.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 339, doi. 10.1093/toxsci/kfv134

By:

Hong Sik Yoo;
Cichocki, Joseph A.;
Sungkyoon Kim;
Venkatratnam, Abhishek;
Yasuhiro Iwata;
Oksana Kosyk;
Bodnar, Wanda;
Sweet, Stephen;
Knap, Anthony;
Wade, Terry;
Campbell, Jerry;
Clewell, Harvey J.;
Melnyk, Stepan B.;
Chiu, Weihsueh A.;
Rusyn, Ivan

Publication type:

Article

Integrated Transcriptional and Proteomic Analysis of Growth Hormone Suppression Mediated by Trichothecene T-2 Toxin in Rat GH3 Cells.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 326, doi. 10.1093/toxsci/kfv131

By:

Dan Wan;
Xu Wang;
Qinghua Wu;
Pingping Lin;
Yuanhu Pan;
Sattar, Adeel;
Lingli Huang;
Ahmad, Ijaz;
Yuanyuan Zhang;
Zonghui Yuan

Publication type:

Article

Long-term Fluorometholone Topical Use Induces Ganglion Cell Damage in Rats Analyzed With Optical Coherence Tomography.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 317, doi. 10.1093/toxsci/kfv132

By:

Cheng-Hui Lin;
Po-Lin Liao;
George Hsiao;
Ching-Hao Li;
Shih-Hsuan Huang;
Chi-Hao Tsai;
Man-Ru Wu;
Fan-Li Lin;
Jau-Der Ho;
Hui-Wen Cheng;
Yu-Wen Cheng

Publication type:

Article

Adaptive Posttranslational Control in Cellular Stress Response Pathways and Its Relationship to Toxicity Testing and Safety Assessment.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 302, doi. 10.1093/toxsci/kfv130

By:

Qiang Zhang;
Bhattacharya, Sudin;
Jingbo Pi;
Clewell, Rebecca A.;
Carmichael, Paul L.;
Andersen, Melvin E.

Publication type:

Article

Letters from Science Camp.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 301, doi. 10.1093/toxsci/kfv187

By:

Miller, Gary W.

Publication type:

Article

Model Systems for Understanding Mechanisms of Nongenotoxic Carcinogenesis: Response.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 299, doi. 10.1093/toxsci/kfv175

By:

Braeuning, Albert;
Henderson, Colin J.;
Wolf, C. Roland;
Schwarz, Michael

Publication type:

Article

The Mode of Action for Phenobarbital-Induced Rodent Liver Tumor Formation Is not Relevant for Humans: Recent Studies With Humanized Mice.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 298, doi. 10.1093/toxsci/kfv173

By:

Tomoya Yamada;
Cohen, Samuel M.;
Lake, Brian G.

Publication type:

Article

Editor's Highlights.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 297, doi. 10.1093/toxsci/kfv186

By:

Hales, Barbara;
Campen, Matthew J.;
Peters, Jeffrey M.;
Cummings, Brian

Publication type:

Article

From the Editor's Desk.

Published in:

Toxicological Sciences, 2015, v. 147, n. 2, p. 297, doi. 10.1093/toxsci/kfv186

By:

Miller, Gary W.

Publication type:

Article