Works matching IS 10966080 AND DT 2014 AND VI 142 AND IP 1

Results: 28

P450-Mediated O-Demethylated Metabolite Is Responsible for Rat Hepatobiliary Toxicity of Pyridyltriazine-Containing PI3K Inhibitors.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 298, doi. 10.1093/toxsci/kfu178

By:

Subramanian, Raju;
Aidasani, Divesh;
Bailey, Keith;
Branstetter, Dan;
Everds, Nancy;
Jian Jiang;
Norman, Mark H.;
Primack, Ronya;
Skiles, Gary L.;
Soto, Irene;
Stec, Markian M.;
Wagner, Mylo;
Tian Wu;
Xiaochun Zhu;
Lebrec, Hervé

Publication type:

Article

Altered Surfactant Homeostasis and Alveolar Epithelial Cell Stress in Amiodarone-Induced Lung Fibrosis.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 285, doi. 10.1093/toxsci/kfu177

By:

Mahavadi, Poornima;
Henneke, Ingrid;
Ruppert, Clemens;
Knudsen, Lars;
Venkatesan, Shalini;
Liebisch, Gerhard;
Chambers, Rachel C.;
Ocha, Matthias;
Schmitz, Gerd;
Vancheri, Carlo;
Seeger, Werner;
Korfei, Martina;
Guenther, Andreas

Publication type:

Article

Impairment of Glutamate Signaling in Mouse Central Nervous System Neurons In Vitro by Tri-Ortho-Cresyl Phosphate at Noncytotoxic Concentrations.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 274, doi. 10.1093/toxsci/kfu174

By:

Hausherr, Vanessa;
van Thriel, Christoph;
Krug, Anne;
Leist, Marcel;
Schöbel, Nicole

Publication type:

Article

A Systematic Assessment of Mitochondrial Function Identified Novel Signatures for Drug-Induced Mitochondrial Disruption in Cells.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 261, doi. 10.1093/toxsci/kfu176

By:

Nianyu Li;
Oquendo, Elisa;
Capaldi, Roderick A.;
Robinson, J. Paul;
He, Yudong D.;
Hamadeh, Hisham K.;
Afshari, Cynthia A.;
Lightfoot-Dunn, Ruth;
Narayanan, Padma Kumar

Publication type:

Article

Novel Hg2+-Induced Nephropathy in Rats and Mice Lacking Mrp2: Evidence of Axial Heterogeneity in the Handling of Hg2+ Along the Proximal Tubule.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 250, doi. 10.1093/toxsci/kfu171

By:

Zalups, Rudolfs K.;
Joshee, Lucy;
Bridges, Christy C.

Publication type:

Article

Stable Isotope Labeling Method for the Investigation of Protein Haptenation by Electrophilic Skin Sensitizers.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 239, doi. 10.1093/toxsci/kfu168

By:

Parkinson, Erika;
Boyd, Pete;
Aleksic, Maja;
Cubberley, Richard;
O'Connor, David;
Skipp, Paul

Publication type:

Article

Cardiac Epithelial-Mesenchymal Transition Is Blocked by Monomethylarsonous Acid (III).

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 225, doi. 10.1093/toxsci/kfu170

By:

Tianfang Huang;
Barnett, Joey V.;
Camenisch, Todd D.

Publication type:

Article

Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 210, doi. 10.1093/toxsci/kfu169

By:

Wetmore, Barbara A.;
Allen, Brittany;
Clewell III, Harvey J.;
Parker, Timothy;
Wambaugh, John F.;
Almond, Lisa M.;
Sochaski, Mark A.;
Thomas, Russell S.

Publication type:

Article

SLC19A1, SLC46A1 and SLCO1B1 Polymorphisms as Predictors of Methotrexate-Related Toxicity in Portuguese Rheumatoid Arthritis Patients.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 196, doi. 10.1093/toxsci/kfu162

By:

Lima, Aurea;
Bernardes, Miguel;
Azevedo, Rita;
Monteiro, Joaquim;
Sousa, Hugo;
Medeiros, Rui;
Seabra, Vítor

Publication type:

Article

Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 182, doi. 10.1093/toxsci/kfu164

By:

Pan Guo;
Huifeng Pi;
Shangcheng Xu;
Lei Zhang;
Yuming Li;
Min Li;
Zhengwang Cao;
Li Tian;
Jia Xie;
Renyan Li;
Mindi He;
Yonghui Lu;
Chuan Liu;
Weixia Duan;
Zhengping Yu;
Zhou Zhou

Publication type:

Article

Comparison of Anorectic and Emetic Potencies of Deoxynivalenol (Vomitoxin) to the Plant Metabolite Deoxynivalenol-3-Glucoside and Synthetic Deoxynivalenol Derivatives EN139528 and EN139544.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 167, doi. 10.1093/toxsci/kfu166

By:

Wenda Wu;
Hui-Ren Zhou;
Bursian, Steven J.;
Xiao Pan;
Link, Jane E.;
Berthiller, Franz;
Adam, Gerhard;
Kantis, Anthony;
Durst, Tony;
Pestka, James J.

Publication type:

Article

Autoantibodies Associated with Prenatal and Childhood Exposure to Environmental Chemicals in Faroese Children.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 158, doi. 10.1093/toxsci/kfu163

By:

Osuna, Christa E.;
Grandjean, Philippe;
Weihe, Pál;
El-Fawal, Hassan A. N.

Publication type:

Article

Human Hepatocytes Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogen Sodium Phenobarbital in an In Vivo Study Using a Chimeric Mouse with Humanized Liver.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 137, doi. 10.1093/toxsci/kfu173

By:

Tomoya Yamada;
Yu Okuda;
Masahiko Kushida;
Kayo Sumida;
Hayato Takeuchi;
Hirohisa Nagahori;
Takako Fukuda;
Lake, Brian G.;
Cohen, Samuel M.;
Satoshi Kawamura

Publication type:

Article

Tissue Sensitivity of the Rat Upper and Lower Extrapulmonary Airways to the Inhaled Electrophilic Air Pollutants Diacetyl and Acrolein.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 126, doi. 10.1093/toxsci/kfu165

By:

Cichocki, Joseph A.;
Smith, Gregory J.;
Morris, John B.

Publication type:

Article

Homologous Recombination Repair Signaling in Chemical Carcinogenesis: Prolonged Particulate Hexavalent Chromium Exposure Suppresses the Rad51 Response in Human Lung Cells.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 117, doi. 10.1093/toxsci/kfu175

By:

Qin Qin;
Hong Xie;
Wise, Sandra S.;
Browning, Cynthia L.;
Thompson, Kelsey N.;
Holmes, Amie L.;
Wise Sr., John Pierce

Publication type:

Article

Systems Level Metabolic Phenotype of Methotrexate Administration in the Context of Non-alcoholic Steatohepatitis in the Rat.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 105, doi. 10.1093/toxsci/kfu160

By:

Kyriakides, Michael;
Hardwick, Rhiannon N.;
Zhaosheng Jin;
Goedken, Michael J.;
Holmes, Elaine;
Cherrington, Nathan J.;
Coen, Muireann

Publication type:

Article

Arsenic Exposure Disrupts the Normal Function of the FA/BRCA Repair Pathway.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 93, doi. 10.1093/toxsci/kfu159

By:

Peremartí, Jana;
Ramos, Facundo;
Marcos, Ricard;
Hernández, Alba

Publication type:

Article

Characterization of Nuclear Receptor-Mediated Murine Hepatocarcinogenesis of the Herbicide Pronamide and Its Human Relevance.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 74, doi. 10.1093/toxsci/kfu155

By:

LeBaron, Matthew J.;
Rasoulpour, Reza J.;
Gollapudi, B. Bhaskar;
Sura, Radhakrishna;
Kan, H. Lynn;
Schisler, Melissa R.;
Pottenger, Lynn H.;
Papineni, Sabitha;
Eisenbrandt, David L.

Publication type:

Article

Profiling Dose-Dependent Activation of p53-Mediated Signaling Pathways by Chemicals with Distinct Mechanisms of DNA Damage.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 56, doi. 10.1093/toxsci/kfu153

By:

Clewell, Rebecca A.;
Bin Sun;
Adeleye, Yeyejide;
Carmichael, Paul;
Efremenko, Alina;
McMullen, Patrick D.;
Pendse, Salil;
Trask, O. J.;
White, Andy;
Andersen, Melvin E.

Publication type:

Article

Increased Susceptibility to Methotrexate-Induced Toxicity in Nonalcoholic Steatohepatitis.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 45, doi. 10.1093/toxsci/kfu156

By:

Hardwick, Rhiannon N.;
Clarke, John D.;
Lake, April D.;
Canet, Mark J.;
Anumol, Tarun;
Street, Stephanie M.;
Merrell, Matthew D.;
Goedken, Michael J.;
Snyder, Shane A.;
Cherrington, Nathan J.

Publication type:

Article

The Role of Autophagy in Usnic Acid-Induced Toxicity in Hepatic Cells.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 33, doi. 10.1093/toxsci/kfu154

By:

Si Chen;
Dobrovolsky, Vasily N.;
Fang Liu;
Yuanfeng Wu;
Zhuhong Zhang;
Nan Mei;
Lei Guo

Publication type:

Article

Normalization of Nano-Sized TiO2-Induced Clastogenicity, Genotoxicity and Mutagenicity by Chlorophyllin Administration in Mice Brain, Liver, and Bone Marrow Cells.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 21, doi. 10.1093/toxsci/kfu157

By:

El-Ghor, Akmal A.;
Noshy, Magda M.;
Galal, Ahmad;
Mohamed, Hanan Ramadan H.

Publication type:

Article

AMP-Activated Protein Kinase Deficiency Rescues Paraquat-Induced Cardiac Contractile Dysfunction Through an Autophagy-Dependent Mechanism.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 6, doi. 10.1093/toxsci/kfu158

By:

Qiurong Wang;
Lifang Yang;
Yinan Hua;
Nair, Sreejayan;
Xihui Xu;
Jun Ren

Publication type:

Article

Contemporary Reviews in Toxicology.

Published in:

2014

By:

Johnson, Jeffrey A.;
Miller, Gary W.

Publication type:

Editorial

Application of Hemodynamic Shear Stress to Endothelial Cell Cultures: The Sine Qua Non For In Vivo Translatability or a Potential Contributing Factor?

Published in:

2014

By:

Kustermann, Stefan;
Manigold, Tobias;
Roth, Adrian

Publication type:

Letter to the Editor

Exposure of Endothelial Cells to Hemodynamic Shear Stress In Vitro Is Necessary for In Vivo [Or Clinical] Translation of Response.

Published in:

2014

By:

Turk, James R.;
Wayne Orr, Amgen A.

Publication type:

Letter to the Editor

Editor's Highlights.

Published in:: Toxicological Sciences, 2014, v. 142, n. 1, p. 1, doi. 10.1093/toxsci/kfu209
Publication type:: Article

From the Editor's Desk.

Published in:

Toxicological Sciences, 2014, v. 142, n. 1, p. 1, doi. 10.1093/toxsci/kfu209

By:

Miller, Gary W.

Publication type:

Article

Works matching IS 10966080 AND DT 2014 AND VI 142 AND IP 1

P450-Mediated O-Demethylated Metabolite Is Responsible for Rat Hepatobiliary Toxicity of Pyridyltriazine-Containing PI3K Inhibitors.

Altered Surfactant Homeostasis and Alveolar Epithelial Cell Stress in Amiodarone-Induced Lung Fibrosis.

Impairment of Glutamate Signaling in Mouse Central Nervous System Neurons In Vitro by Tri-Ortho-Cresyl Phosphate at Noncytotoxic Concentrations.

A Systematic Assessment of Mitochondrial Function Identified Novel Signatures for Drug-Induced Mitochondrial Disruption in Cells.

Novel Hg<sup>2+</sup>-Induced Nephropathy in Rats and Mice Lacking Mrp2: Evidence of Axial Heterogeneity in the Handling of Hg<sup>2+</sup> Along the Proximal Tubule.

Stable Isotope Labeling Method for the Investigation of Protein Haptenation by Electrophilic Skin Sensitizers.

Cardiac Epithelial-Mesenchymal Transition Is Blocked by Monomethylarsonous Acid (III).

Incorporating Population Variability and Susceptible Subpopulations into Dosimetry for High-Throughput Toxicity Testing.

SLC19A1, SLC46A1 and SLCO1B1 Polymorphisms as Predictors of Methotrexate-Related Toxicity in Portuguese Rheumatoid Arthritis Patients.

Melatonin Improves Mitochondrial Function by Promoting MT1/SIRT1/PGC-1 Alpha-Dependent Mitochondrial Biogenesis in Cadmium-Induced Hepatotoxicity In Vitro.

Comparison of Anorectic and Emetic Potencies of Deoxynivalenol (Vomitoxin) to the Plant Metabolite Deoxynivalenol-3-Glucoside and Synthetic Deoxynivalenol Derivatives EN139528 and EN139544.

Autoantibodies Associated with Prenatal and Childhood Exposure to Environmental Chemicals in Faroese Children.

Human Hepatocytes Support the Hypertrophic but not the Hyperplastic Response to the Murine Nongenotoxic Hepatocarcinogen Sodium Phenobarbital in an In Vivo Study Using a Chimeric Mouse with Humanized Liver.

Tissue Sensitivity of the Rat Upper and Lower Extrapulmonary Airways to the Inhaled Electrophilic Air Pollutants Diacetyl and Acrolein.

Homologous Recombination Repair Signaling in Chemical Carcinogenesis: Prolonged Particulate Hexavalent Chromium Exposure Suppresses the Rad51 Response in Human Lung Cells.

Systems Level Metabolic Phenotype of Methotrexate Administration in the Context of Non-alcoholic Steatohepatitis in the Rat.

Arsenic Exposure Disrupts the Normal Function of the FA/BRCA Repair Pathway.

Characterization of Nuclear Receptor-Mediated Murine Hepatocarcinogenesis of the Herbicide Pronamide and Its Human Relevance.

Profiling Dose-Dependent Activation of p53-Mediated Signaling Pathways by Chemicals with Distinct Mechanisms of DNA Damage.

Increased Susceptibility to Methotrexate-Induced Toxicity in Nonalcoholic Steatohepatitis.

The Role of Autophagy in Usnic Acid-Induced Toxicity in Hepatic Cells.

Normalization of Nano-Sized TiO<sub>2</sub>-Induced Clastogenicity, Genotoxicity and Mutagenicity by Chlorophyllin Administration in Mice Brain, Liver, and Bone Marrow Cells.

AMP-Activated Protein Kinase Deficiency Rescues Paraquat-Induced Cardiac Contractile Dysfunction Through an Autophagy-Dependent Mechanism.

Contemporary Reviews in Toxicology.

Application of Hemodynamic Shear Stress to Endothelial Cell Cultures: The Sine Qua Non For In Vivo Translatability or a Potential Contributing Factor?

Exposure of Endothelial Cells to Hemodynamic Shear Stress In Vitro Is Necessary for In Vivo [Or Clinical] Translation of Response.

Editor's Highlights.

From the Editor's Desk.