Works matching IS 10966080 AND DT 2020 AND VI 177 AND IP 1


Results: 26
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    Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline.

    Published in:
    Toxicological Sciences, 2020, v. 177, n. 1, p. 121, doi. 10.1093/toxsci/kfaa094
    By:
    • Kang, Wen;
    • Podtelezhnikov, Alexei A;
    • Tanis, Keith Q;
    • Pacchione, Stephen;
    • Su, Ming;
    • Bleicher, Kimberly B;
    • Wang, Zhibin;
    • Laws, George M;
    • Griffiths, Thomas G;
    • Kuhls, Matthew C;
    • Chen, Qing;
    • Knemeyer, Ian;
    • Marsh, Donald J;
    • Mitra, Kaushik;
    • Lebron, Jose;
    • Sistare, Frank D
    Publication type:
    Article
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    Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury.

    Published in:
    Toxicological Sciences, 2020, v. 177, n. 1, p. 281, doi. 10.1093/toxsci/kfaa088
    By:
    • Monroe, James J;
    • Tanis, Keith Q;
    • Podtelezhnikov, Alexei A;
    • Nguyen, Truyen;
    • Machotka, Sam V;
    • Lynch, Donna;
    • Evers, Raymond;
    • Palamanda, Jairam;
    • Miller, Randy R;
    • Pippert, Todd;
    • Cabalu, Tamara D;
    • Johnson, Timothy E;
    • Aslamkhan, Amy G;
    • Kang, Wen;
    • Tamburino, Alex M;
    • Mitra, Kaushik;
    • Agrawal, Nancy G B;
    • Sistare, Frank D
    Publication type:
    Article
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    Corrigendum to: "A Novel, Modified Human Butyrylcholinesterase Catalytically Degrades the Chemical Warfare Nerve Agent, Sarin".

    Published in:
    Toxicological Sciences, 2020, v. 177, n. 1, p. 300, doi. 10.1093/toxsci/kfaa057
    By:
    • McGarry, Kevin G;
    • Lalisse, Remy F;
    • Moyer, Robert A;
    • Johnson, Kristyn M;
    • Tallan, Alexi M;
    • Winters, Tyson P;
    • Taris, Joseph E;
    • McElroy, Craig A;
    • Lemmon, Erin E;
    • Shafaat, Hannah S;
    • Fan, Yamin;
    • Deal, Aniliese;
    • Marguet, Sean C;
    • Harvilchuck, Jill A;
    • Hadad, Christopher M;
    • Wood, David W
    Publication type:
    Article
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