Works matching IS 10966080 AND DT 2020 AND VI 176 AND IP 2

Results: 15

Evaluation of 5-day In Vivo Rat Liver and Kidney With High-throughput Transcriptomics for Estimating Benchmark Doses of Apical Outcomes.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 343, doi. 10.1093/toxsci/kfaa081

By:

Gwinn, William M;
Auerbach, Scott S;
Parham, Fred;
Stout, Matthew D;
Waidyanatha, Suramya;
Mutlu, Esra;
Collins, Brad;
Paules, Richard S;
Merrick, Bruce Alex;
Ferguson, Stephen;
Ramaiahgari, Sreenivasa;
Bucher, John R;
Sparrow, Barney;
Toy, Heather;
Gorospe, Jenni;
Machesky, Nick;
Shah, Ruchir R;
Balik-Meisner, Michele R;
Mav, Deepak;
Phadke, Dhiral P

Publication type:

Article

Single-cell RNA-seq Analysis Reveals That Prenatal Arsenic Exposure Results in Long-term, Adverse Effects on Immune Gene Expression in Response to Influenza A Infection.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 312, doi. 10.1093/toxsci/kfaa080

By:

Hsu, Kevin S;
Goodale, Britton C;
Ely, Kenneth H;
Hampton, Thomas H;
Stanton, Bruce A;
Enelow, Richard I

Publication type:

Article

Manganese-induced Mitochondrial Dysfunction Is Not Detectable at Exposures Below the Acute Cytotoxic Threshold in Neuronal Cell Types.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 446, doi. 10.1093/toxsci/kfaa079

By:

Warren, Emily B;
Bryan, Miles R;
Morcillo, Patricia;
Hardeman, Keisha N;
Aschner, Michael;
Bowman, Aaron B

Publication type:

Article

Combining In Vivo and Organotypic In Vitro Approaches to Assess the Human Relevance of Basimglurant (RG7090), a Potential CAR Activator.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 329, doi. 10.1093/toxsci/kfaa076

By:

Nudischer, Ramona;
Renggli, Kasper;
Bertinetti-Lapatki, Cristina;
Hoflack, Jean-Christophe;
Flint, Nicholas;
Sewing, Sabine;
Pedersen, Lykke;
Schadt, Simone;
Higgins, Larry G;
Vardy, Audrey;
Lenz, Barbara;
Gand, Laurent;
Boess, Franziska;
Elcombe, Barbara M;
Hierlemann, Andreas;
Roth, Adrian B

Publication type:

Article

Genetic Determinants of Reduced Arsenic Metabolism Efficiency in the 10q24.32 Region Are Associated With Reduced AS3MT Expression in Multiple Human Tissue Types.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 382, doi. 10.1093/toxsci/kfaa075

By:

Chernoff, Meytal;
Tong, Lin;
Demanelis, Kathryn;
Griend, Donald Vander;
Ahsan, Habib;
Pierce, Brandon L

Publication type:

Article

Lead Impairs the Development of Innate Lymphoid Cells by Impeding the Differentiation of Their Progenitors.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 410, doi. 10.1093/toxsci/kfaa074

By:

Zhu, Tingting;
Zhao, Yifan;
Zhang, Peng;
Shao, Yiming;
He, Jinyi;
Xue, Peng;
Zheng, Weiwei;
Qu, Weidong;
Jia, Xiaodong;
Zhou, Zhijun;
Lu, Rongzhu;
He, Miao;
Zhang, Yubin

Publication type:

Article

Biotransformation Capacity of Zebrafish (Danio rerio) Early Life Stages: Functionality of the Mercapturic Acid Pathway.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 355, doi. 10.1093/toxsci/kfaa073

By:

Tierbach, Alena;
Groh, Ksenia J;
Schönenberger, René;
Schirmer, Kristin;
Suter, Marc J -F

Publication type:

Article

Characterizations of Human UDP-Glucuronosyltransferase Enzymes in the Conjugation of p-Cresol.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 285, doi. 10.1093/toxsci/kfaa072

By:

Rong, Yan;
Kiang, Tony K L

Publication type:

Article

Functional Pathway Identification With CRISPR/Cas9 Genome-wide Gene Disruption in Human Dopaminergic Neuronal Cells Following Chronic Treatment With Dieldrin.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 366, doi. 10.1093/toxsci/kfaa071

By:

Russo, Max;
Sobh, Amin;
Zhang, Ping;
Loguinov, Alex;
Tagmount, Abderrahmane;
Vulpe, Chris D;
Liu, Bin

Publication type:

Article

Physiologically Based Pharmacokinetic Modeling in Risk Assessment: Case Study With Pyrethroids.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 460, doi. 10.1093/toxsci/kfaa070

By:

Mallick, Pankajini;
Song, Gina;
Efremenko, Alina Y;
Pendse, Salil N;
Creek, Moire R;
Osimitz, Thomas G;
Hines, Ronald N;
Hinderliter, Paul;
Clewell, Harvey J;
Lake, Brian G;
Yoon, Miyoung;
Moreau, Marjory

Publication type:

Article

Single-Cell Analysis of the Gene Expression Effects of Developmental Lead (Pb) Exposure on the Mouse Hippocampus.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 396, doi. 10.1093/toxsci/kfaa069

By:

Bakulski, Kelly M;
Dou, John F;
Thompson, Robert C;
Lee, Christopher;
Middleton, Lauren Y;
Perera, Bambarendage P U;
Ferris, Sean P;
Jones, Tamara R;
Neier, Kari;
Zhou, Xiang;
Sartor, Maureen A;
Hammoud, Saher S;
Dolinoy, Dana C;
Colacino, Justin A

Publication type:

Article

The GARDpotency Assay for Potency-Associated Subclassification of Chemical Skin Sensitizers—Rationale, Method Development, and Ring Trial Results of Predictive Performance and Reproducibility.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 423, doi. 10.1093/toxsci/kfaa068

By:

Gradin, Robin;
Johansson, Angelica;
Forreryd, Andy;
Aaltonen, Emil;
Jerre, Anders;
Larne, Olivia;
Mattson, Ulrika;
Johansson, Henrik

Publication type:

Article

Quantification of the Uncertainties in Extrapolating From In Vitro Androgen Receptor Antagonism to In Vivo Hershberger Assay Endpoints and Adverse Reproductive Development in Male Rats.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 297, doi. 10.1093/toxsci/kfaa067

By:

Gray, Leon E;
Furr, Johnathan R;
Lambright, Christy S;
Evans, Nicola;
Hartig, Phillip C;
Cardon, Mary C;
Wilson, Vickie S;
Hotchkiss, Andrew K;
Conley, Justin M

Publication type:

Article

Coordinated Action of miR-146a and Parkin Gene Regulate Rotenone-induced Neurodegeneration.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 433, doi. 10.1093/toxsci/kfaa066

By:

Jauhari, Abhishek;
Singh, Tanisha;
Mishra, Saumya;
Shankar, Jai;
Yadav, Sanjay

Publication type:

Article

The Impact of Environmental Chemicals on the Gut Microbiome.

Published in:

Toxicological Sciences, 2020, v. 176, n. 2, p. 253, doi. 10.1093/toxsci/kfaa065

By:

Chiu, Karen;
Warner, Genoa;
Nowak, Romana A;
Flaws, Jodi A;
Mei, Wenyan

Publication type:

Article