Works matching DE "PARKIN (Protein)"
Results: 263
Cell biology: Balancing act.
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- Nature, 2014, v. 510, n. 7505, p. 347, doi. 10.1038/nature13500
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Neurological disorders: Quality-control pathway unlocked.
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- Nature, 2014, v. 510, n. 7503, p. 44, doi. 10.1038/510044a
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- Article
Ubiquitin is phosphorylated by PINK1 to activate parkin.
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- Nature, 2014, v. 510, n. 7503, p. 162, doi. 10.1038/nature13392
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High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
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- Nature, 2013, v. 504, n. 7479, p. 291, doi. 10.1038/nature12748
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The ubiquitin ligase parkin mediates resistance to intracellular pathogens.
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- Nature, 2013, v. 501, n. 7468, p. 512, doi. 10.1038/nature12566
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Cell biology: A table for two.
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- Nature, 2013, v. 501, n. 7468, p. 498, doi. 10.1038/nature12555
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PARKIN is not required to sustain OXPHOS function in adult mammalian tissues.
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- NPJ Parkinson's Disease, 2024, v. 10, n. 1, p. 1, doi. 10.1038/s41531-024-00707-0
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Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system.
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- Journal of Cell Biology, 2016, v. 214, n. 3, p. 275, doi. 10.1083/jcb.201603105
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Phosphorylated ubiquitin chain is the genuine Parkin receptor.
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- Journal of Cell Biology, 2015, v. 209, n. 1, p. 111, doi. 10.1083/jcb.201410050
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PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding.
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- Journal of Cell Biology, 2013, v. 200, n. 2, p. 163, doi. 10.1083/jcb.201210111
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- Article
Dual mechanism of DICER downregulation facilitates cancer metastasis.
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- Molecular & Cellular Oncology, 2018, v. 5, n. 5, p. 1, doi. 10.1080/23723556.2018.1472056
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The role of Parkin protein in cardiac function and ventricular remodeling in myocardial infarction rats.
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- European Review for Medical & Pharmacological Sciences, 2018, v. 22, n. 15, p. 5004
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Role of mitophagy regulated by Parkin/DJ-1 in remote ischemic postconditioning-induced mitigation of focal cerebral ischemia-reperfusion injury in rats.
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- European Review for Medical & Pharmacological Sciences, 2015, v. 19, n. 24, p. 4866
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In Silico Investigation of Parkin-Activating Mutations Using Simulations and Network Modeling.
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- Biomolecules (2218-273X), 2024, v. 14, n. 3, p. 365, doi. 10.3390/biom14030365
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Advancements in Genetic and Biochemical Insights: Unraveling the Etiopathogenesis of Neurodegeneration in Parkinson's Disease.
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- Biomolecules (2218-273X), 2024, v. 14, n. 1, p. 73, doi. 10.3390/biom14010073
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Parkin Inhibits RANKL-Induced Osteoclastogenesis and Ovariectomy-Induced Bone Loss.
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- Biomolecules (2218-273X), 2022, v. 12, n. 11, p. 1602, doi. 10.3390/biom12111602
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Parkin as a Molecular Bridge Linking Alzheimer's and Parkinson's Diseases?
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- Biomolecules (2218-273X), 2022, v. 12, n. 4, p. 559, doi. 10.3390/biom12040559
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Parkin regulates IGF2BP3 through ubiquitination in the tumourigenesis of cervical cancer.
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- Clinical & Translational Medicine, 2023, v. 13, n. 10, p. 1, doi. 10.1002/ctm2.1457
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LncRNA LOC105378097 inhibits cardiac mitophagy in natural ageing mice.
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- Clinical & Translational Medicine, 2022, v. 12, n. 6, p. 1, doi. 10.1002/ctm2.908
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Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38080-w
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Parkin regulates adiposity by coordinating mitophagy with mitochondrial biogenesis in white adipocytes.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34468-2
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Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32689-z
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Parkin mediates mitophagy during beige-to-white fat conversion.
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- Science Signaling, 2018, v. 11, n. 527, p. 1, doi. 10.1126/scisignal.aat1082
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Deconstructing the molecular genetics behind the PINK1/Parkin axis in Parkinson's disease using Drosophila melanogaster as a model organism.
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- Egyptian Journal of Medical Human Genetics, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s43042-021-00208-2
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Dynamics of Mitochondrial Transport in Axons.
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- Frontiers in Cellular Neuroscience, 2016, p. 1, doi. 10.3389/fncel.2016.00123
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NF-κB in neurodegenerative diseases: Recent evidence from human genetics.
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- Frontiers in Molecular Neuroscience, 2022, v. 15, p. 01, doi. 10.3389/fnmol.2022.954541
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The Transcription Factor Function of Parkin: Breaking the Dogma.
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- Frontiers in Neuroscience, 2019, p. N.PAG, doi. 10.3389/fnins.2018.00965
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荷斯坦奶牛 DPP6 和 PRKN 基因的 生物信息学及表达规律分析.
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- Southwest China Journal of Agricultural Sciences, 2024, v. 37, n. 1, p. 210, doi. 10.16213/j.cnki.scjas.2024.1.024
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Dexmedetomidine improves myocardial ischemia-reperfusion injury by increasing autophagy via PINK1/PRKN pathway.
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- Signa Vitae, 2022, v. 18, n. 5, p. 125, doi. 10.22514/sv.2022.061
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The Absence of Parkin Does Not Promote Dopamine or Mitochondrial Dysfunction in PolgA<sup>D257A/D257A</sup> Mitochondrial Mutator Mice.
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- Journal of Neuroscience, 2022, v. 42, n. 49, p. 9263, doi. 10.1523/JNEUROSCI.0545-22.2022
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Loss of HIPK2 Protects Neurons from Mitochondrial Toxins by Regulating Parkin Protein Turnover.
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- Journal of Neuroscience, 2020, v. 40, n. 3, p. 557, doi. 10.1523/JNEUROSCI.2017-19.2019
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Interactions of VMAT2 with CDCrel-1 and Parkin in Methamphetamine Neurotoxicity.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 23, p. 13070, doi. 10.3390/ijms252313070
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Mitochondrial DNA Instability Supersedes Parkin Mutations in Driving Mitochondrial Proteomic Alterations and Functional Deficits in Polg Mutator Mice.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 12, p. 6441, doi. 10.3390/ijms25126441
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History of Parkinson's Disease-Associated Gene, Parkin : Research over a Quarter Century in Quest of Finding the Physiological Substrate.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 23, p. 16734, doi. 10.3390/ijms242316734
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Sex Influence on Autophagy Markers and miRNAs in Basal and Angiotensin II-Treated Human Umbilical Vein Endothelial Cells.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14929, doi. 10.3390/ijms241914929
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Parkin-Mediated Mitophagy by TGF-β Is Connected with Hepatic Stellate Cell Activation.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 19, p. 14826, doi. 10.3390/ijms241914826
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Parkin Precipitates on Mitochondria via Aggregation and Autoubiquitination.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 10, p. 9027, doi. 10.3390/ijms24109027
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Enhanced IRE1α Phosphorylation/Oligomerization-Triggered XBP1 Splicing Contributes to Parkin-Mediated Prevention of SH-SY5Y Cell Death under Nitrosative Stress.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 3, p. 2017, doi. 10.3390/ijms24032017
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An Inverse Agonist GSK5182 Increases Protein Stability of the Orphan Nuclear Receptor ERRγ via Inhibition of Ubiquitination.
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- International Journal of Molecular Sciences, 2023, v. 24, n. 1, p. 96, doi. 10.3390/ijms24010096
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NEAT1 Confers Radioresistance to Hepatocellular Carcinoma Cells by Inducing PINK1/Parkin-Mediated Mitophagy.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 22, p. 14397, doi. 10.3390/ijms232214397
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Targeting Deubiquitinating Enzymes (DUBs) That Regulate Mitophagy via Direct or Indirect Interaction with Parkin.
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- 2022
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- Literature Review
Mitochondrial Dysfunction in Spinocerebellar Ataxia Type 3 Is Linked to VDAC1 Deubiquitination.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 11, p. 5933, doi. 10.3390/ijms23115933
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Dopamine and Methamphetamine Differentially Affect Electron Transport Chain Complexes and Parkin in Rat Striatum: New Insight into Methamphetamine Neurotoxicity.
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- International Journal of Molecular Sciences, 2022, v. 23, n. 1, p. 363, doi. 10.3390/ijms23010363
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A Splice Intervention Therapy for Autosomal Recessive Juvenile Parkinson's Disease Arising from Parkin Mutations.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 19, p. 7282, doi. 10.3390/ijms21197282
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PINK1/Parkin Mediated Mitophagy, Ca2+ Signalling, and ER–Mitochondria Contacts in Parkinson's Disease.
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- International Journal of Molecular Sciences, 2020, v. 21, n. 5, p. 1772, doi. 10.3390/ijms21051772
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Melatonin Enhances Mitophagy by Upregulating Expression of Heat Shock 70 kDa Protein 1L in Human Mesenchymal Stem Cells under Oxidative Stress.
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- International Journal of Molecular Sciences, 2019, v. 20, n. 18, p. 4545, doi. 10.3390/ijms20184545
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Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells.
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- International Journal of Molecular Sciences, 2015, v. 16, n. 6, p. 13356, doi. 10.3390/ijms160613356
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Phosphorylation by PINK1 Releases the UBL Domain and Initializes the Conformational Opening of the E3 Ubiquitin Ligase Parkin.
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- PLoS Computational Biology, 2014, v. 10, n. 11, p. 1, doi. 10.1371/journal.pcbi.1003935
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Discovery of Small Molecule PARKIN Activator from Antipsychotic/Anti-neuropsychiatric Drugs as Therapeutics for PD: an In Silico Repurposing Approach.
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- Applied Biochemistry & Biotechnology, 2023, v. 195, n. 10, p. 5980, doi. 10.1007/s12010-023-04376-2
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Study of the Effects of Nicotine and Caffeine for the Treatment of Parkinson's Disease.
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- Applied Biochemistry & Biotechnology, 2023, v. 195, n. 1, p. 639, doi. 10.1007/s12010-022-04155-5
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