Works matching DE "POLYCYSTINS"

Results: 86

Hypertension in autosomal-dominant polycystic kidney disease (ADPKD).

Published in:

Clinical Kidney Journal, 2013, v. 6, n. 5, p. 457, doi. 10.1093/ckj/sft031

By:

Sans-Atxer, Laia;
Torra, Roser;
Fernández-Llama, Patricia

Publication type:

Article

Lipid bilayer-atomic force microscopy combined platform records simultaneous electrical and topological changes of the TRP channel polycystin-2 (TRPP2).

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0202029

By:

Lal, Sumit;
Scarinci, Noelia;
Perez, Paula L.;
Cantero, María del Rocío;
Cantiello, Horacio F.

Publication type:

Article

Overexpression of the Polycystin-1 C-Tail Enhances Sensitivity of M-1 Cells to Ouabain.

Published in:

Journal of Membrane Biology, 2013, v. 246, n. 7, p. 581, doi. 10.1007/s00232-013-9573-4

By:

Jansson, Kyle;
Magenheimer, Brenda;
Maser, Robin;
Calvet, James;
Blanco, Gustavo

Publication type:

Article

The Primary cilium calcium channels and their role in flow sensing.

Published in:

Pflügers Archiv: European Journal of Physiology, 2015, v. 467, n. 1, p. 157, doi. 10.1007/s00424-014-1516-0

By:

Patel, Amanda

Publication type:

Article

Gating modulation by heat of the polycystin transient receptor potential channel PKD2L1 (TRPP3).

Published in:

Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 10, p. 1933, doi. 10.1007/s00424-013-1439-1

By:

Higuchi, Taiga;
Shimizu, Takahiro;
Fujii, Takuto;
Nilius, Bernd;
Sakai, Hideki

Publication type:

Article

Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.

Published in:

Pflügers Archiv: European Journal of Physiology, 2014, v. 466, n. 8, p. 1591, doi. 10.1007/s00424-013-1394-x

By:

Mekahli, Djalila;
Decuypere, Jean-Paul;
Sammels, Eva;
Welkenhuyzen, Kirsten;
Schoeber, Joost;
Audrezet, Marie-Pierre;
Corvelyn, Anniek;
Dechênes, Georges;
Ong, Albert;
Wilmer, Martijn;
Heuvel, Lambertus;
Bultynck, Geert;
Parys, Jan;
Missiaen, Ludwig;
Levtchenko, Elena;
Smedt, Humbert

Publication type:

Article

Novel insights into TRPV4 function in the kidney.

Published in:

Pflügers Archiv: European Journal of Physiology, 2013, v. 465, n. 2, p. 177, doi. 10.1007/s00424-012-1190-z

By:

Pochynyuk, Oleh;
Zaika, Oleg;
O'Neil, Roger;
Mamenko, Mykola

Publication type:

Article

The Role of G-Protein-Coupled Receptor Proteolysis Site Cleavage of Polycystin-1 in Renal Physiology and Polycystic Kidney Disease.

Published in:

Cells (2073-4409), 2016, v. 5, n. 1, p. 3, doi. 10.3390/cells5010003

By:

Trudel, Marie;
Qin Yao;
Feng Qian

Publication type:

Article

Role of the Polycystins in Cell Migration, Polarity, and Tissue Morphogenesis.

Published in:

Cells (2073-4409), 2015, v. 4, n. 4, p. 687, doi. 10.3390/cells4040687

By:

Nigro, Elisa Agnese;
Castelli, Maddalena;
Boletta, Alessandra

Publication type:

Article

Too close not to encyst: Polycystic kidney disease and interorganellar contact sites.

Published in:

Science Signaling, 2019, v. 12, n. 583, p. N.PAG, doi. 10.1126/scisignal.aaw6996

By:

Lorenzi, Isotta;
Scorrano, Luca

Publication type:

Article

Polycystin 2 regulates mitochondrial Ca2+ signaling, bioenergetics, and dynamics through mitofusin 2.

Published in:

Science Signaling, 2019, v. 12, n. 580, p. N.PAG, doi. 10.1126/scisignal.aat7397

By:

Kuo, Ivana Y.;
Brill, Allison L.;
Lemos, Fernanda O.;
Jiang, Jason Y.;
Falcone, Jeffrey L.;
Kimmerling, Erica P.;
Cai, Yiqiang;
Dong, Ke;
Kaplan, David L.;
Wallace, Darren P.;
Hofer, Aldebaran M.;
Ehrlich, Barbara E.

Publication type:

Article

Filamin-A Increases the Stability and Plasma Membrane Expression of Polycystin-2.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123018

By:

Wang, Qian;
Zheng, Wang;
Wang, Zuocheng;
Yang, JungWoo;
Hussein, Shaimaa;
Tang, Jingfeng;
Chen, Xing-Zhen

Publication type:

Article

OFD1 and Flotillins Are Integral Components of a Ciliary Signaling Protein Complex Organized by Polycystins in Renal Epithelia and Odontoblasts.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106330

By:

Jerman, Stephanie;
Ward, Heather H.;
Lee, Rebecca;
Lopes, Carla A. M.;
Fry, Andrew M.;
MacDougall, Mary;
Wandinger-Ness, Angela

Publication type:

Article

Radiologic and Clinical Bronchiectasis Associated with Autosomal Dominant Polycystic Kidney Disease.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0093674

By:

Moua, Teng;
Zand, Ladan;
Hartman, Robert P.;
Hartman, Thomas E.;
Qin, Dingxin;
Peikert, Tobias;
Qian, Qi

Publication type:

Article

Polycystin-1 Mediates Mechanical Strain-Induced Osteoblastic Mechanoresponses via Potentiation of Intracellular Calcium and Akt/β-Catenin Pathway.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0091730

By:

Wang, Hua;
Sun, Wen;
Ma, Junqing;
Pan, Yongchu;
Wang, Lin;
Zhang, Weibing

Publication type:

Article

Loss of Polycystin-1 Inhibits Bicc1 Expression during Mouse Development.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0088816

By:

Lian, Peiwen;
Li, Ao;
Li, Yuan;
Liu, Haichao;
Liang, Dan;
Hu, Bo;
Lin, De;
Jiang, Tang;
Moeckel, Gilbert;
Qin, Dahui;
Wu, Guanqing

Publication type:

Article

Morphology, Distribution and Phenotype of Polycystin Kidney Disease 2-like 1-Positive Cerebrospinal Fluid Contacting Neurons in The Brainstem of Adult Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0087748

By:

Orts-Del’Immagine, Adeline;
Kastner, Anne;
Tillement, Vanessa;
Tardivel, Catherine;
Trouslard, Jérôme;
Wanaverbecq, Nicolas

Publication type:

Article

TRPP2 and TRPV4 Form an EGF-Activated Calcium Permeable Channel at the Apical Membrane of Renal Collecting Duct Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0073424

By:

Zhang, Zhi-Ren;
Chu, Wen-Feng;
Song, Binlin;
Gooz, Monika;
Zhang, Jia-Ning;
Yu, Chang-Jiang;
Jiang, Shuai;
Baldys, Aleksander;
Gooz, Pal;
Steele, Stacy;
Owsianik, Grzegorz;
Nilius, Bernd;
Komlosi, Peter;
Bell, P. Darwin

Publication type:

Article

Müller Cell Reactivity in Response to Photoreceptor Degeneration in Rats with Defective Polycystin-2.

Published in:

PLoS ONE, 2013, v. 8, n. 6, p. 1, doi. 10.1371/journal.pone.0061631

By:

Vogler, Stefanie;
Pannicke, Thomas;
Hollborn, Margrit;
Grosche, Antje;
Busch, Stephanie;
Hoffmann, Sigrid;
Wiedemann, Peter;
Reichenbach, Andreas;
Hammes, Hans-Peter;
Bringmann, Andreas

Publication type:

Article

Structural Interaction and Functional Regulation of Polycystin-2 by Filamin.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040448

By:

Qian Wang;
Xiao-Qing Dai;
Qiang Li;
Zuocheng Wang;
del Rocío Cantero, María;
Shu Li;
Ji Shen;
Jian-Cheng Tu;
Cantiello, Horacio;
Xing-Zhen Chen

Publication type:

Article

The number and location of EF hand motifs dictates the calcium dependence of polycystin-2 function.

Published in:

FASEB Journal, 2014, v. 28, n. 5, p. 2332, doi. 10.1096/fj.13-247106

By:

Kuo, Ivana Y.;
Keeler, Camille;
Corbin, Rachel;
Ćelić, Andjelka;
Petri, Edward T.;
Hodsdon, Michael E.;
Ehrlich, Barbara E.

Publication type:

Article

Inhibition of CaV3.2 T-type calcium channels in peripheral sensory neurons contributes to analgesic properties of epipregnanolone.

Published in:

Psychopharmacology, 2014, v. 231, n. 17, p. 3503, doi. 10.1007/s00213-014-3588-0

By:

Ayoola, Christine;
Hwang, Sung;
Hong, Sung;
Rose, Kirstin;
Boyd, Christopher;
Bozic, Neda;
Park, Ji-Yong;
Osuru, Hari;
DiGruccio, Michael;
Covey, Douglas;
Jevtovic-Todorovic, Vesna;
Todorovic, Slobodan

Publication type:

Article

Analysis of the REJ Module of Polycystin-1 Using Molecular Modeling and Force-Spectroscopy Techniques.

Published in:

Journal of Biophysics, 2013, p. 1, doi. 10.1155/2013/525231

By:

Meixiang Xu;
Lian Ma;
Bujalowski, Paul J.;
Feng Qian;
Sutton, R. Bryan;
Oberhauser, Andres F.

Publication type:

Article

Novel cilia-dependent pathway activates rapid cyst growth in autosomal dominant polycystic kidney disease.

Published in:

Clinical Genetics, 2014, v. 85, n. 3, p. 230, doi. 10.1111/cge.12285

By:

Patankar, J.V.

Publication type:

Article

PKD2/polycystin-2 induces autophagy by forming a complex with BECN1.

Published in:

Autophagy, 2021, v. 17, n. 7, p. 1714, doi. 10.1080/15548627.2020.1782035

By:

Peña-Oyarzun, Daniel;
Rodriguez-Peña, Marcelo;
Burgos-Bravo, Francesca;
Vergara, Angelo;
Kretschmar, Catalina;
Sotomayor-Flores, Cristian;
Ramirez-Sarmiento, Cesar A.;
De Smedt, Humbert;
Reyes, Montserrat;
Perez, William;
Torres, Vicente A.;
Morselli, Eugenia;
Altamirano, Francisco;
Wilson, Christian A. M.;
Hill, Joseph A.;
Lavandero, Sergio;
Criollo, Alfredo

Publication type:

Article

Expression of polycystins and fibrocystin on primary cilia of lung cells1.

Published in:

Biochemistry & Cell Biology, 2014, v. 92, n. 6, p. 547, doi. 10.1139/bcb-2014-0062

By:

Hu, Qiaolin;
Wu, Yuliang;
Tang, Jingfeng;
Zheng, Wang;
Wang, Qian;
Nahirney, Drew;
Duszyk, Marek;
Wang, Shaohua;
Tu, Jian-Cheng;
Chen, Xing-Zhen

Publication type:

Article

TRPs revisited.

Published in:

Acta Physiologica, 2015, v. 214, n. 1, p. 6, doi. 10.1111/apha.12492

By:

Persson, P. B.

Publication type:

Article

Genetic Analysis Reveals a Hierarchy of Interactions between Polycystin-Encoding Genes and Genes Controlling Cilia Function during Left-Right Determination.

Published in:

PLoS Genetics, 2016, v. 12, n. 6, p. 1, doi. 10.1371/journal.pgen.1006070

By:

Grimes, Daniel T.;
Keynton, Jennifer L.;
Buenavista, Maria T.;
Jin, Xingjian;
Patel, Saloni H.;
Kyosuke, Shinohara;
Vibert, Jennifer;
Williams, Debbie J.;
Hamada, Hiroshi;
Hussain, Rohanah;
Nauli, Surya M.;
Norris, Dominic P.

Publication type:

Article

Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity.

Published in:

Journal of Clinical Investigation, 2012, v. 122, n. 11, p. 4257, doi. 10.1172/JCI64313

By:

Hopp, Katharina;
Ward, Christopher J.;
Hommerding, Cynthia J.;
Nasr, Samih H.;
Han-Fang Tuan;
Gainullin, Vladimir G.;
Rossetti, Sandro;
Torres, Vicente E.;
Harris, Peter C.

Publication type:

Article

Regulation of CFTR Expression and Arginine Vasopressin Activity Are Dependent on Polycystin-1 in Kidney-Derived Cells.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2016, v. 38, n. 1, p. 28, doi. 10.1159/000438606

By:

de Lemos Barbosa, Carolina Monteiro;
Souza-Menezes, Jackson;
amaral, andressa Godoy;
Onuchic, Luiz Fernando;
Cebotaru, Liudmila;
Guggino, William B.;
Morales, Marcelo M.

Publication type:

Article

Acid-induced off-response of PKD2L1 channel in Xenopus oocytes and its regulation by Ca2+.

Published in:

Scientific Reports, 2015, p. 15752, doi. 10.1038/srep15752

By:

Hussein, Shaimaa;
Zheng, Wang;
Dyte, Chris;
Wang, Qian;
Yang, JungWoo;
Zhang, Fan;
Tang, Jingfeng;
Cao, Ying;
Chen, Xing-Zhen

Publication type:

Article

Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity.

Published in:

Scientific Reports, 2015, p. 13461, doi. 10.1038/srep13461

By:

Varela, Aimilia;
Piperi, Christina;
Sigala, Fragiska;
Agrogiannis, George;
Davos, Constantinos H.;
Andri, Maria-Anastasia;
Manopoulos, Christos;
Tsangaris, Sokrates;
Basdra, Efthimia K.;
Papavassiliou, Athanasios G.

Publication type:

Article

Polycystin deficiency induces dopamine-reversible alterations in flow-mediated dilatation and vascular nitric oxide release in humans.

Published in:

Kidney International, 2015, v. 87, n. 2, p. 465, doi. 10.1038/ki.2014.241

By:

Lorthioir, Aurélien;
Joannidès, Robinson;
Rémy-Jouet, Isabelle;
Fréguin-Bouilland, Caroline;
Iacob, Michèle;
Roche, Clothilde;
Monteil, Christelle;
Lucas, Danièle;
Renet, Sylvanie;
Audrézet, Marie-Pierre;
Godin, Michel;
Richard, Vincent;
Thuillez, Christian;
Guerrot, Dominique;
Bellien, Jérémy

Publication type:

Article

Impaired Purinergic Regulation of the Glial (Müller) Cell Volume in the Retina of Transgenic Rats Expressing Defective Polycystin-2.

Published in:

Neurochemical Research, 2016, v. 41, n. 7, p. 1784, doi. 10.1007/s11064-016-1894-0

By:

Vogler, Stefanie;
Pannicke, Thomas;
Hollborn, Margrit;
Kolibabka, Matthias;
Wiedemann, Peter;
Reichenbach, Andreas;
Hammes, Hans-Peter;
Bringmann, Andreas

Publication type:

Article

Molecular evolution of candidate sour taste receptor gene PKD1L3 in mammals.

Published in:

Genome, 2011, v. 54, n. 11, p. 890, doi. 10.1139/G11-057

By:

Dazhi Chen;
Ping Li;
Wenhu Guo;
Fang Ye;
Jian Wu;
Damu Wei;
Zhiyun Guo;
Chun Ye

Publication type:

Article

Role of polycystin-1 in bone remodeling: Orthodontic tooth movement study in mutant mice.

Published in:

Angle Orthodontist, 2014, v. 84, n. 5, p. 885, doi. 10.2319/082313-620.1

By:

Shalish, Miriam;
Will, Leslie A.;
Naomi Fukai;
Bo Hou;
Olsen, Björn R.

Publication type:

Article

Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease.

Published in:

Physiological Reports, 2015, v. 3, n. 5, p. n/a, doi. 10.14814/phy2.12405

By:

Saigusa, Takamitsu;
Dang, Yujing;
Bunni, Marlene A.;
Amria, May Y.;
Steele, Stacy L.;
Fitzgibbon, Wayne R.;
Bell, P. Darwin

Publication type:

Article

Adaptive selection drives TRPP3 loss-of-function in an Ethiopian population.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-78081-z

By:

Walsh, Sandra;
Izquierdo-Serra, Mercè;
Acosta, Sandra;
Edo, Albert;
Lloret, María;
Moret, Roser;
Bosch, Elena;
Oliva, Baldo;
Bertranpetit, Jaume;
Fernández-Fernández, José Manuel

Publication type:

Article

Polycystin-1 interacts with TAZ to stimulate osteoblastogenesis and inhibit adipogenesis.

Published in:

2018

By:

Zhousheng Xiao;
Baudry, Jerome;
Li Cao;
Jinsong Huang;
Hao Chen;
Yates, Charles R.;
Wei Li;
Dong, Brittany;
Waters, Christopher M.;
Smith, Jeremy C.;
Quarles, L. Darryl;
Xiao, Zhousheng;
Cao, Li;
Huang, Jinsong;
Chen, Hao;
Li, Wei

Publication type:

journal article

Isolated polycystic liver disease genes define effectors of polycystin-1 function.

Published in:

2017

By:

Besse, Whitney;
Dong, Ke;
Choi, Jungmin;
Punia, Sohan;
Fedeles, Sorin V;
Choi, Murim;
Gallagher, Anna-Rachel;
Huang, Emily B;
Gulati, Ashima;
Knight, James;
Mane, Shrikant;
Tahvanainen, Esa;
Tahvanainen, Pia;
Sanna-Cherchi, Simone;
Lifton, Richard P;
Watnick, Terry;
Pei, York P;
Torres, Vicente E;
Somlo, Stefan

Publication type:

journal article

Isolated polycystic liver disease genes define effectors of polycystin-1 function.

Published in:

2017

By:

Besse, Whitney;
Ke Dong;
Jungmin Choi;
Punia, Sohan;
Fedeles, Sorin V.;
Choi, Murim;
Gallagher, Anna-Rachel;
Huang, Emily B.;
Gulati, Ashima;
Knight, James;
Mane, Shrikant;
Tahvanainen, Esa;
Tahvanainen, Pia;
Sanna-Cherchi, Simone;
Lifton, Richard P.;
Watnickw, Terry;
Pei, York P.;
Torres, Vicente E.;
Somlo, Stefan;
Dong, Ke

Publication type:

journal article

Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.

Published in:

Journal of Clinical Investigation, 2015, v. 125, n. 2, p. 607, doi. 10.1172/JCI76972

By:

Gainullin, Vladimir G.;
Hopp, Katharina;
Ward, Christopher J.;
Hommerding, Cynthia J.;
Harris, Peter C.

Publication type:

Article

Altered trafficking and stability of polycystins underlie polycystic kidney disease.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 12, p. 5129, doi. 10.1172/JCI67273

By:

Yiqiang Cai;
Fedeles, Sorin V.;
Ke Dong;
Anyatonwu, Georgia;
Onoe, Tamehito;
Mitobe, Michihiro;
Jian-Dong Gao;
Okuhara, Dayne;
Xin Tian;
Gallagher, Anna-Rachel;
Zhangui Tang;
Xiaoli Xie;
Lalioti, Maria D.;
Lee, Ann-Hwee;
Ehrlich, Barbara E.;
Somlo, Stefan

Publication type:

Article

Genetic mechanisms and signaling pathways in autosomal dominant polycystic kidney disease.

Published in:

Journal of Clinical Investigation, 2014, v. 124, n. 6, p. 2315, doi. 10.1172/JCI72272

By:

Harris, Peter C.;
Torres, Vicente E.

Publication type:

Article

The mitochondrial transporter SLC25A25 links ciliary TRPP2 signaling and cellular metabolism.

Published in:

PLoS Biology, 2018, v. 16, n. 8, p. 1, doi. 10.1371/journal.pbio.2005651

By:

Hofherr, Alexis;
Seger, Claudia;
Fitzpatrick, Fiona;
Busch, Tilman;
Michel, Elisabeth;
Luan, Jingting;
Osterried, Lea;
Linden, Frieder;
Kramer-Zucker, Albrecht;
Wakimoto, Barbara;
Schütze, Conny;
Wiedemann, Nils;
Artati, Anna;
Adamski, Jerzy;
Walz, Gerd;
Kunji, Edmund R. S.;
Montell, Craig;
Watnick, Terry;
Köttgen, Michael

Publication type:

Article

Continuous hydrostatic pressure induces differentiation phenomena in chondrocytes mediated by changes in polycystins, SOX9, and RUNX2.

Published in:

Journal of Orofacial Orthopedics/Fortschritte der Kieferorthopadie, 2017, v. 78, n. 1, p. 21, doi. 10.1007/s00056-016-0061-1

By:

Karamesinis, Konstantinos;
Spyropoulou, Anastasia;
Dalagiorgou, Georgia;
Katsianou, Maria;
Nokhbehsaim, Marjan;
Memmert, Svenja;
Deschner, James;
Vastardis, Heleni;
Piperi, Christina

Publication type:

Article

Renal injury progression in autosomal dominant polycystic kidney disease: a look beyond the cysts.

Published in:

Nephrology Dialysis Transplantation, 2018, v. 33, n. 11, p. 1887, doi. 10.1093/ndt/gfy023

By:

Raptis, Vasileios;
Loutradis, Charalampos;
Sarafidis, Pantelis A

Publication type:

Article

Hereditary polycystic kidney disease is characterized by lymphopenia across all stages of kidney dysfunction: an observational study.

Published in:

Nephrology Dialysis Transplantation, 2018, v. 33, n. 3, p. 489, doi. 10.1093/ndt/gfx040

By:

Van Laecke, Steven;
Kerre, Tessa;
Nagler, Evi V.;
Maes, Bart;
Caluwe, Rogier;
Schepers, Eva;
Glorieux, Griet;
Van Biesen, Wim;
Verbeke, Francis

Publication type:

Article

The ciliary flow sensor and polycystic kidney disease.

Published in:

Nephrology Dialysis Transplantation, 2013, v. 28, n. 3, p. 518, doi. 10.1093/ndt/gfs524

By:

Kotsis, Fruzsina;
Boehlke, Christopher;
Kuehn, E. Wolfgang

Publication type:

Article

mTOR inhibition in autosomal-dominant polycystic kidney disease (ADPKD): the question remains open.

Published in:

Nephrology Dialysis Transplantation, 2013, v. 28, n. 2, p. 242, doi. 10.1093/ndt/gfs519

By:

Jardine, Meg J.;
Liyanage, Thaminda;
Buxton, Erin;
Perkovic, Vlado

Publication type:

Article