Works matching DE "PROPROTEIN convertases"

Results: 377

Oxidized low-density lipoprotein (oxLDL) affects load-free cell shortening of cardiomyocytes in a proprotein convertase subtilisin/kexin 9 (PCSK9)-dependent way.

Published in:

Basic Research in Cardiology, 2017, v. 112, n. 6, p. 1, doi. 10.1007/s00395-017-0650-1

By:

Schlüter, Klaus-Dieter;
Wolf, Annemarie;
Weber, Martin;
Schreckenberg, Rolf;
Schulz, Rainer

Publication type:

Article

Proapelin is processed extracellularly in a cell line-dependent manner with clear modulation by proprotein convertases.

Published in:

Amino Acids, 2019, v. 51, n. 3, p. 395, doi. 10.1007/s00726-018-2674-8

By:

Shin, Kyungsoo;
Landsman, Michael;
Pelletier, Stephanie;
Alamri, Bader N.;
Anini, Younes;
Rainey, Jan K.

Publication type:

Article

Non-cross-linking advanced glycation end products affect prohormone processing.

Published in:

Biochemical Journal, 2024, v. 481, n. 1, p. 33, doi. 10.1042/BCJ20230321

By:

Brings, Sebastian;
Mier, Walter;
Beijer, Barbro;
Kliemank, Elisabeth;
Herzig, Stephan;
Szendroedi, Julia;
Nawroth, Peter P.;
Fleming, Thomas

Publication type:

Article

The association of serum proprotein convertase furin/PCSK3 concentrations with stable coronary artery disease and coroner artery lesion severity.

Published in:

International Journal of Medical Biochemistry, 2024, v. 7, n. 1, p. 18, doi. 10.14744/ijmb.2023.09326

By:

Yucesan, Fulya Balaban;
Orem, Asim;
Orem, Cihan;
Ilter, Abdulselam;
Yaman, Serap Ozer;
Yaman, Huseyin;
Akcan, Buket;
Sen, Tugba Mazlum

Publication type:

Article

PCSK9 in African Americans and Caucasians in Relation to Lp(a) Level, Apo(a) Size and Heritability.

Published in:

Journal of the Endocrine Society, 2020, v. 4, n. 7, p. 1, doi. 10.1210/jendso/bvaa073

By:

Enkhmaa, Byambaa;
Kim, Kyoungmi;
Zhang, Wei;
Prakash, Nishant;
Truax, Kevin;
Anuurad, Erdembileg;
Berglund, Lars

Publication type:

Article

PCSK9 Inhibitors in a Statin-Intolerant Transgender Man With Heterozygous Familial Hypercholesterolemia: A Case Report.

Published in:

2019

By:

Pirazzi, Carlo;
Tavaglione, Federica;
Tivesten, Åsa;
Romeo, Stefano

Publication type:

Case Study

Proprotein convertase subtilisin/kexin type 6 activates the extracellular signal-regulated kinase 1/2 and Wnt family member 3A pathways and promotes in vitro proliferation, migration and invasion of breast cancer MDA-MB-231 cells.

Published in:

Oncology Letters, 2018, v. 16, n. 1, p. 145, doi. 10.3892/ol.2018.8654

By:

Wang, Ping;
Wang, Feifei;
Wang, Lin;
Pan, Jihong

Publication type:

Article

Post-Transcriptional Effects of miRNAs on PCSK7 Expression and Function: miR-125a-5p, miR-143-3p, and miR-409-3p as Negative Regulators.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 7, p. N.PAG, doi. 10.3390/metabo12070588

By:

Malakootian, Mahshid;
Naeli, Parisa;
Mowla, Seyed Javad;
Seidah, Nabil G.

Publication type:

Article

Insight into the Evolving Role of PCSK9.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 3, p. 256, doi. 10.3390/metabo12030256

By:

Maligłówka, Mateusz;
Kosowski, Michał;
Hachuła, Marcin;
Cyrnek, Marcin;
Bułdak, Łukasz;
Basiak, Marcin;
Bołdys, Aleksandra;
Machnik, Grzegorz;
Bułdak, Rafał Jakub;
Okopień, Bogusław

Publication type:

Article

C3-Glomerulopathy Autoantibodies Mediate Distinct Effects on Complement C3- and C5-Convertases.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.01030

By:

Zhao, Fei;
Afonso, Sara;
Lindner, Susanne;
Hartmann, Andrea;
Löschmann, Ina;
Nilsson, Bo;
Ekdahl, Kristina N.;
Weber, Lutz T.;
Habbig, Sandra;
Schalk, Gesa;
Kirschfink, Michael;
Zipfel, Peter F.;
Skerka, Christine

Publication type:

Article

Ultraviolet B irradiation of the mouse eye induces pigmentation of the skin more strongly than does stress loading, by increasing the levels of prohormone convertase 2 and α-melanocyte-stimulating hormone.

Published in:

Clinical & Experimental Dermatology, 2013, v. 38, n. 1, p. 71, doi. 10.1111/j.1365-2230.2012.04439.x

By:

Hiramoto, K.;
Yamate, Y.;
Kobayashi, H.;
Ishii, M.;
Sato, E. F.;
Inoue, M.

Publication type:

Article

Proprotein convertase 5/6A is associated with bone morphogenetic protein‐2‐induced squamous cell differentiation.

Published in:

Clinical & Translational Allergy, 2015, v. 5, n. 4, p. 1, doi. 10.1186/2045-7022-5-S4-P20

By:

Yoon, Joo‐Heon;
Lee, Sang‐Nam

Publication type:

Article

In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23.

Published in:

Frontiers in Endocrinology, 2021, v. 12, p. 1, doi. 10.3389/fendo.2021.690681

By:

Al Rifai, Omar;
Susan-Resiga, Delia;
Essalmani, Rachid;
Creemers, John W. M.;
Seidah, Nabil G.;
Ferron, Mathieu

Publication type:

Article

Inhibition of PCSK9 protects against radiationinduced damage of prostate cancer cells.

Published in:

OncoTargets & Therapy, 2017, v. 10, p. 2139, doi. 10.2147/OTT.S129413

By:

Si-Shun Gan;
Jian-Qing Ye;
Lei Wang;
Fa-Jun Qu;
Chuan-Min Chu;
Yi-Jun Tian;
Wei Yang;
Xin-Gang Cui

Publication type:

Article

Effect of food intake on 92 oncological biomarkers by the Proseek Oncology II panel.

Published in:

BMC Research Notes, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13104-019-4237-9

By:

Dencker, Magnus;
Björgell, Ola;
Hlebowicz, Joanna

Publication type:

Article

A PCSK9 e sua relevância clínica com os novos alvos terapêuticos contra a dislipidemia.

Published in:

Einstein (16794508), 2012, v. 10, n. 4, p. 526

By:

dos Santos Ferreira, Carlos Eduardo;
Helfenstein Fonseca, Francisco Antônio;
Pitangueira Mangueira, Cristóvão Luis

Publication type:

Article

PCSK9 loss-of-function variants and risk of infection and sepsis in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohort.

Published in:

PLoS ONE, 2019, v. 14, n. 2, p. 1, doi. 10.1371/journal.pone.0210808

By:

Mitchell, Kellie A.;
Moore, Justin Xavier;
Rosenson, Robert S.;
Irvin, Ryan;
Guirgis, Faheem W.;
Shapiro, Nathan;
Safford, Monika;
Wang, Henry E.

Publication type:

Article

Treatment of hypercholesterolaemia with PCSK9 inhibitors in patients after cardiac transplantation.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0210373

By:

Kühl, Michael;
Binner, Christian;
Jozwiak, Joanna;
Fischer, Julia;
Hahn, Jochen;
Addas, Alaeldin;
Dinov, Boris;
Garbade, Jens;
Hindricks, Gerhard;
Borger, Michael

Publication type:

Article

Neisseria Heparin Binding Antigen is targeted by the human alternative pathway C3-convertase.

Published in:

PLoS ONE, 2018, v. 13, n. 3, p. 1, doi. 10.1371/journal.pone.0194662

By:

Di Fede, Martina;
Biagini, Massimiliano;
Cartocci, Elena;
Parillo, Carlo;
Greco, Alessandra;
Martinelli, Manuele;
Marchi, Sara;
Pezzicoli, Alfredo;
Delany, Isabel;
Rossi Paccani, Silvia

Publication type:

Article

Malaria severity: Possible influence of the E670G PCSK9 polymorphism: A preliminary case-control study in Malian children.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0192850

By:

Arama, Charles;
Diarra, Issa;
Kouriba, Bourèma;
Sirois, Francine;
Fedoryak, Olesya;
Thera, Mahamadou A.;
Coulibaly, Drissa;
Lyke, Kirsten E.;
Plowe, Christopher V.;
Chrétien, Michel;
Doumbo, Ogobara K.;
Mbikay, Majambu

Publication type:

Article

Development of vaccine for dyslipidemia targeted to a proprotein convertase subtilisin/kexin type 9 (PCSK9) epitope in mice.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0191895

By:

Kawakami, Ryo;
Nozato, Yoichi;
Nakagami, Hironori;
Ikeda, Yuka;
Shimamura, Munehisa;
Yoshida, Shota;
Sun, Jiao;
Kawano, Tomohiro;
Takami, Yoichi;
Noma, Takahisa;
Rakugi, Hiromi;
Minamino, Tetsuo;
Morishita, Ryuichi

Publication type:

Article

Prohormone convertase 2 activity is increased in the hippocampus of Wfs1 knockout mice.

Published in:

Frontiers in Molecular Neuroscience, 2015, v. 8, p. 1, doi. 10.3389/fnmol.2015.00045

By:

Tein, Karin;
Kasvandik, Sergo;
Kõks, Sulev;
Vasar, Eero;
Terasmaa, Anton

Publication type:

Article

PCSK6-mediated corin activation is essential for normal blood pressure.

Published in:

Nature Medicine, 2015, v. 21, n. 9, p. 1048, doi. 10.1038/nm.3920

By:

Chen, Shenghan;
Cao, Pengxiu;
Dong, Ningzheng;
Peng, Jianhao;
Zhang, Chunyi;
Wang, Hao;
Zhou, Tiantian;
Yang, Junhua;
Zhang, Yue;
Martelli, Elizabeth E;
Naga Prasad, Sathyamangla V;
Miller, Rachel E;
Malfait, Anne-Marie;
Zhou, Yiqing;
Wu, Qingyu

Publication type:

Article

Case-control study on PCSK9 R496W (rs374603772) and D374Y (rs137852912) mutations in Turkish patients with primary dyslipidemia.

Published in:

2018

By:

Eroğlu, Zuhal;
Vardarlı, Aslı Tetik;
Düzgün, Zekeriya;
Gündüz, Cumhur;
Çetintaş, Vildan Bozok;
Kayıkçıoğlu, Meral

Publication type:

Abstract

PCSK 9 gain-of-function mutations (R496W and D374Y) and clinical cardiovascular characteristics in a cohort of Turkish patients with familial hypercholesterolemia.

Published in:

Anatolian Journal of Cardiology / Anadolu Kardiyoloji Dergisi, 2017, v. 18, n. 4, p. 266, doi. 10.14744/AnatolJCardiol.2017.7654

By:

Kaya, Esra;
Kayıkçıoğlu, Meral;
Vardarlı, Aslı Tetik;
Eroğlu, Zuhal;
Payzın, Serdar;
Can, Levent

Publication type:

Article

Evaluation of cardiac biomarkers and right ventricular dysfunction in patients with acute pulmonary embolism.

Published in:

Anatolian Journal of Cardiology / Anadolu Kardiyoloji Dergisi, 2016, v. 16, n. 4, p. 276, doi. 10.5152/akd.2014.5828

By:

Dursunoğlu, Neşe;
Dursunoğlu, Dursun;
Yıldız, Ali İhsan;
Rota, Simin

Publication type:

Article

SUMO Wrestling in the Airway Epithelium: Does It Regulate Thymic Stromal Lymphopoietin?

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 66, n. 6, p. 591, doi. 10.1165/rcmb.2021-0558ED

By:

Gounni, Abdelilah S.;
Koussih, Latifa

Publication type:

Article

Ghrelin O-acyltransferase (GOAT) is expressed in prostate cancer tissues and cell lines and expression is differentially regulated in vitro by ghrelin.

Published in:

Reproductive Biology & Endocrinology, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1477-7827-11-70

By:

Seim, Inge;
Jeffery, Penny L.;
de Amorim, Laura;
Walpole, Carina M.;
Fung, Jenny;
Whiteside, Eliza J.;
Lourie, Rohan;
Herington, Adrian C.;
Chopin, Lisa K.

Publication type:

Article

Dysregulation of FURIN and Other Proprotein Convertase Genes in the Progression from HPV Infection to Cancer.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 2, p. 461, doi. 10.3390/ijms26020461

By:

Izaguirre, Gonzalo;
Zirou, Natalia;
Meyers, Craig

Publication type:

Article

Deciphering the dual nature of nesfatin-1: a tale of zinc ion's Janus-faced influence.

Published in:

Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01675-x

By:

Lenda, Rafał;
Zhukova, Lilia;
Ożyhar, Andrzej;
Bystranowska, Dominika

Publication type:

Article

Polydatin ameliorates lipid and glucose metabolism in type 2 diabetes mellitus by downregulating proprotein convertase subtilisin/kexin type 9 (PCSK9).

Published in:

Cardiovascular Diabetology, 2016, v. 15, p. 1, doi. 10.1186/s12933-015-0325-x

By:

Yu Wang;
Jiantao Ye;
Jie Li;
Cheng Chen;
Junying Huang;
Peiqing Liu;
Heqing Huang

Publication type:

Article

Identification of proprotein convertase substrates using genome-wide expression correlation analysis.

Published in:: BMC Genomics, 2011, v. 12, n. Suppl 2, p. 618, doi. 10.1186/1471-2164-12-618
Publication type:: Article

Cleavage of a Neuroinvasive Human Respiratory Virus Spike Glycoprotein by Proprotein Convertases Modulates Neurovirulence and Virus Spread within the Central Nervous System.

Published in:

PLoS Pathogens, 2015, v. 11, n. 11, p. 1, doi. 10.1371/journal.ppat.1005261

By:

Le Coupanec, Alain;
Desforges, Marc;
Meessen-Pinard, Mathieu;
Dubé, Mathieu;
Day, Robert;
Seidah, Nabil G.;
Talbot, Pierre J.

Publication type:

Article

Cilia-based peptidergic signaling.

Published in:

PLoS Biology, 2019, v. 17, n. 12, p. 1, doi. 10.1371/journal.pbio.3000566

By:

Luxmi, Raj;
Kumar, Dhivya;
Mains, Richard E.;
King, Stephen M.;
Eipper, Betty A.

Publication type:

Article

Up-regulation of liver Pcsk9 gene expression as a possible cause of hypercholesterolemia in experimental chronic renal failure.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 411, n. 1/2, p. 281, doi. 10.1007/s11010-015-2590-0

By:

Sucajtys-Szulc, Elzbieta;
Szolkiewicz, Marek;
Swierczynski, Julian;
Rutkowski, Boleslaw

Publication type:

Article

The non-receptor tyrosine kinase c-Src mediates the PDGF-induced association between Furin and pro-MT1-MMP in HPAC pancreatic cells.

Published in:

Molecular & Cellular Biochemistry, 2012, v. 362, n. 1/2, p. 65, doi. 10.1007/s11010-011-1128-3

By:

Shi, Chong;
Ma, Yongchao;
Liu, Hao;
Zhang, Yuxiang;
Wang, Zesheng;
Jia, Hongti

Publication type:

Article

Stigmasterol accumulation causes cardiac injury and promotes mortality.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-018-0245-x

By:

Tao, Caroline;
Shkumatov, Artem A.;
Alexander, Shawn T.;
Ason, Brandon L.;
Zhou, Mingyue

Publication type:

Article

The Effect of Proprotein Convertase Subtilisin/Kexin Type 9 Inhibition on Sterol Absorption Markers in a Cohort of Real-World Patients.

Published in:

2019

By:

Brandt, Eric J.;
Benes, Lane B.;
Lee, Linda;
Dayspring, Thomas D.;
Sorrentino, Matthew;
Davidson, Michael

Publication type:

journal article

Proprotein Convertase Subtilisin/Kexin 9 Inhibitors: An Emerging Lipid-Lowering Therapy?

Published in:

Journal of Cardiovascular Pharmacology & Therapeutics, 2015, v. 20, n. 2, p. 157, doi. 10.1177/1074248414539562

By:

Dragan, Simona;
Serban, Maria-Corina;
Banach, Maciej

Publication type:

Article

Crystallization and X‐ray analysis of monodisperse human properdin.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2019, v. 75, n. 2, p. 0, doi. 10.1107/S2053230X18018150

By:

Pedersen, Dennis Vestergaard;
Revel, Margot;
Gadeberg, Trine Amalie Fogh;
Andersen, Gregers Rom

Publication type:

Article

The complexities of homozygous familial hypercholesterolemia management.

Published in:

2016

By:

Gidding, Samuel S.

Publication type:

Editorial

Urine peptidome analysis in cardiorenal syndrome reflects molecular processes.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95695-z

By:

Petra, Eleni;
He, Tianlin;
Lygirou, Vasiliki;
Latosinska, Agnieszka;
Mischak, Harald;
Vlahou, Antonia;
Jankowski, Joachim

Publication type:

Article

Lack of PCSK6 Increases Flow-Mediated Outward Arterial Remodeling in Mice.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 1009, doi. 10.3390/cells9041009

By:

Röhl, Samuel;
Suur, Bianca E.;
Lengquist, Mariette;
Seime, Till;
Caidahl, Kenneth;
Hedin, Ulf;
Arner, Anders;
Matic, Ljubica;
Razuvaev, Anton

Publication type:

Article

PC1/3 KD Macrophages Exhibit Resistance to the Inhibitory Effect of IL-10 and a Higher TLR4 Activation Rate, Leading to an Anti-Tumoral Phenotype.

Published in:

Cells (2073-4409), 2019, v. 8, n. 12, p. 1490, doi. 10.3390/cells8121490

By:

Rodet, Franck;
Capuz, Alice;
Ozcan, Bilgehan-Aybike;
Le Beillan, Rémy;
Raffo-Romero, Antonella;
Kobeissy, Firas;
Duhamel, Marie;
Salzet, Michel

Publication type:

Article

Elevated Circulating PCSK9 Concentrations Predict Subclinical Atherosclerotic Changes in Low Risk Obese and Non-Obese Patients.

Published in:

Cardiology & Therapy, 2017, v. 6, n. 2, p. 281, doi. 10.1007/s40119-017-0092-8

By:

Tóth, Štefan;
Fedačko, Ján;
Pekárová, Tímea;
Hertelyová, Zdenka;
Katz, Matan;
Mughees, Adil;
Kuzma, Jozef;
Štefanič, Peter;
Kopolovets, Ivan;
Pella, Daniel

Publication type:

Article

Prodomain of the proprotein convertase subtilisin/kexin Furin (ppFurin) protects from tumor progression and metastasis.

Published in:

Carcinogenesis, 2014, v. 35, n. 3, p. 528, doi. 10.1093/carcin/bgt345

By:

Scamuffa, Nathalie;
Sfaxi, Fatma;
Ma, Jia;
Lalou, Claude;
Seidah, Nabil;
Calvo, Fabien;
Khatib, Abdel-Majid

Publication type:

Article

Adiposity Blunts the Positive Relationship of Thyrotropin with Proprotein Convertase Subtilisin-Kexin Type 9 Levels in Euthyroid Subjects.

Published in:

Thyroid, 2013, v. 23, n. 2, p. 166, doi. 10.1089/thy.2012.0434

By:

Kwakernaak, Arjan J.;
Lambert, Gilles;
Muller Kobold, Anneke C.;
Dullaart, Robin P.F.

Publication type:

Article

Cell-specific expression and individual function of prohormone convertase PC1/3 in Tribolium larval growth highlights major evolutionary changes between beetle and fly neuroendocrine systems.

Published in:

EvoDevo, 2021, v. 12, n. 1, p. 1, doi. 10.1186/s13227-021-00179-w

By:

Fritzsche, Sonja;
Hunnekuhl, Vera S.

Publication type:

Article

The Dual α-Amidation System in Scorpion Venom Glands.

Published in:

Toxins, 2019, v. 11, n. 7, p. 425, doi. 10.3390/toxins11070425

By:

Delgado-Prudencio, Gustavo;
Possani, Lourival D.;
Becerril, Baltazar;
Ortiz, Ernesto

Publication type:

Article

Bee Venom Alleviates Atopic Dermatitis Symptoms through the Upregulation of Decay-Accelerating Factor (DAF/CD55).

Published in:

Toxins, 2019, v. 11, n. 5, p. 239, doi. 10.3390/toxins11050239

By:

Kim, Yenny;
Lee, Youn-Woo;
Chung, Dae Kyun;
Kim, Hangeun

Publication type:

Article