Results: 61
Inter-individual variability contrasts with regional homogeneity in the human brain DNA methylome.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 2, p. 732, doi. 10.1093/nar/gku1305
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- Article
Transcriptional inhibition and mutagenesis induced by N-nitroso compound-derived carboxymethylated thymidine adducts in DNA.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1012, doi. 10.1093/nar/gku1391
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- Article
Recognition and cleavage of 5-methylcytosine DNA by bacterial SRA-HNH proteins.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1147, doi. 10.1093/nar/gku1376
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- Article
A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 862, doi. 10.1093/nar/gku1396
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- Article
Transcriptional regulator-mediated activation of adaptation genes triggers CRISPR de novo spacer acquisition.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1044, doi. 10.1093/nar/gku1383
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- Article
DNA binding by FOXP3 domain-swapped dimer suggests mechanisms of long-range chromosomal interactions.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1268, doi. 10.1093/nar/gku1373
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- Article
REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1000, doi. 10.1093/nar/gku1385
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Specific and non-specific interactions of ParB with DNA: implications for chromosome segregation.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 719, doi. 10.1093/nar/gku1295
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- Article
Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1283, doi. 10.1093/nar/gku1374
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- Article
Global coordination in adaptation to gene rewiring.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1304, doi. 10.1093/nar/gku1366
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- Article
Recognition of duplex RNA by the deaminase domain of the RNA editing enzyme ADAR2.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1123, doi. 10.1093/nar/gku1345
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- Article
RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1069, doi. 10.1093/nar/gku1328
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- Article
Bcl2 inhibits recruitment of Mre11 complex to DNA double-strand breaks in response to high-linear energy transfer radiation.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 960, doi. 10.1093/nar/gku1358
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- Article
Escherichia coli antitoxin MazE as transcription factor: insights into MazE-DNA binding.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1241, doi. 10.1093/nar/gku1352
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- Article
SUMO ligase PIAS1 functions as a target gene selective androgen receptor coregulator on prostate cancer cell chromatin.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 848, doi. 10.1093/nar/gku1375
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- Article
A modular system of DNA enhancer elements mediates tissue-specific activation of transcription by high dietary zinc in C. elegans.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 803, doi. 10.1093/nar/gku1360
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- Article
Switching between polymerase and exonuclease sites in DNA polymerase ε.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 932, doi. 10.1093/nar/gku1353
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- Article
Absolute binding-free energies between standard RNA/DNA nucleobases and amino-acid sidechain analogs in different environments.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 708, doi. 10.1093/nar/gku1344
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- Article
Identification of the endosomal sorting complex required for transport-I (ESCRT-I) as an important modulator of anti-miR uptake by cancer cells.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1204, doi. 10.1093/nar/gku1367
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- Article
Structural basis of DNA recognition by PCG2 reveals a novel DNA binding mode for winged helix-turn-helix domains.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1231, doi. 10.1093/nar/gku1351
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Five checkpoints maintaining the fidelity of transcription by RNA polymerases in structural and energetic details.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1133, doi. 10.1093/nar/gku1370
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Systematic evaluation of antibody-mediated siRNA delivery using an industrial platform of THIOMAB–siRNA conjugates.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1189, doi. 10.1093/nar/gku1362
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- Article
A naturally occurring 4-bp deletion in the intron 4 of p53 creates a spectrum of novel p53 isoforms with anti-apoptosis function.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1035, doi. 10.1093/nar/gku1359
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- Article
The architecture of the 12RSS in V(D)J recombination signal and synaptic complexes.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 917, doi. 10.1093/nar/gku1348
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- Article
A structural determinant in the uracil DNA glycosylase superfamily for the removal of uracil from adenine/uracil base pairs.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1081, doi. 10.1093/nar/gku1332
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Modified ribosome profiling reveals high abundance of ribosome protected mRNA fragments derived from 3′ untranslated regions.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1019, doi. 10.1093/nar/gku1310
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- Article
RNA structure generates natural cooperativity between single-stranded RNA binding proteins targeting 5′ and 3′UTRs.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1160, doi. 10.1093/nar/gku1320
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Molecular crowding overcomes the destabilizing effects of mutations in a bacterial ribozyme.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1170, doi. 10.1093/nar/gku1335
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Creating a monomeric endonuclease TALE-I-SceI with high specificity and low genotoxicity in human cells.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1112, doi. 10.1093/nar/gku1339
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Cmr4 is the slicer in the RNA-targeting Cmr CRISPR complex.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1257, doi. 10.1093/nar/gku1355
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Considering the kinetics of mRNA synthesis in the analysis of the genome and epigenome reveals determinants of co-transcriptional splicing.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 699, doi. 10.1093/nar/gku1338
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Regulation of the transcriptional program by DNA methylation during human αβ T-cell development.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 760, doi. 10.1093/nar/gku1340
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Mechanism of RecQ helicase mechanoenzymatic coupling reveals that the DNA interactions of the ADP-bound enzyme control translocation run terminations.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1090, doi. 10.1093/nar/gku1333
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Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1177, doi. 10.1093/nar/gku1343
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Tumor-associated mutations in a conserved structural motif alter physical and biochemical properties of human RAD51 recombinase.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1098, doi. 10.1093/nar/gku1337
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High-resolution HDX-MS reveals distinct mechanisms of RNA recognition and activation by RIG-I and MDA5.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1216, doi. 10.1093/nar/gku1329
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The prion protein is critical for DNA repair and cell survival after genotoxic stress.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 904, doi. 10.1093/nar/gku1342
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Annotating RNA motifs in sequences and alignments.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 691, doi. 10.1093/nar/gku1327
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CRISPR-based self-cleaving mechanism for controllable gene delivery in human cells.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1297, doi. 10.1093/nar/gku1326
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Exploiting post-transcriptional regulation to probe RNA structures in vivo via fluorescence.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1, doi. 10.1093/nar/gku1191
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Direct observation of mobility state transitions in RNA trajectories by sensitive single molecule feedback tracking.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1, doi. 10.1093/nar/gku1194
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Reference-free detection of isolated SNPs.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1, doi. 10.1093/nar/gku1187
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New insights into the QuikChangeTM process guide the use of Phusion DNA polymerase for site-directed mutagenesis.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1, doi. 10.1093/nar/gku1189
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Mechismo: predicting the mechanistic impact of mutations and modifications on molecular interactions.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1, doi. 10.1093/nar/gku1094
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- Article
Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1, doi. 10.1093/nar/gku1090
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- Article
Epidaurus: aggregation and integration analysis of prostate cancer epigenome.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 1, doi. 10.1093/nar/gku1079
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- Article
Chromatin-dependent regulation of RNA polymerases II and III activity throughout the transcription cycle.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 787, doi. 10.1093/nar/gku1349
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- Article
Loop L1 governs the DNA-binding specificity and order for RecA-catalyzed reactions in homologous recombination and DNA repair.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 973, doi. 10.1093/nar/gku1364
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RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway.
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- Nucleic Acids Research, 2015, v. 43, n. 2, p. 893, doi. 10.1093/nar/gku1334
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Subscriptions.
- Published in:
- Nucleic Acids Research, 2015, v. 43, n. 2, p. iii, doi. 10.1093/nar/gkv065
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- Article