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Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil.
- Published in:
- Nucleic Acids Research, 2024, v. 52, n. 20, p. 12534, doi. 10.1093/nar/gkae849
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- Publication type:
- Article
Spatial effects of infiltrating T cells on neighbouring cancer cells and prognosis in stage III CRC patients.
- Published in:
- Journal of Pathology, 2024, v. 264, n. 2, p. 148, doi. 10.1002/path.6327
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- Publication type:
- Article
Epithelial‐to‐mesenchymal transition signature assessment in colorectal cancer quantifies tumour stromal content rather than true transition.
- Published in:
- Journal of Pathology, 2018, v. 246, n. 4, p. 422, doi. 10.1002/path.5155
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- Publication type:
- Article
Vorinostat Eliminates Multicellular Resistance of Mesothelioma 3D Spheroids via Restoration of Noxa Expression.
- Published in:
- PLoS ONE, 2012, v. 7, n. 12, p. 1, doi. 10.1371/journal.pone.0052753
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- Publication type:
- Article
Constitutive and Treatment-Induced CXCL8-Signalling Selectively Modulates the Efficacy of Anti-Metabolite Therapeutics in Metastatic Prostate Cancer.
- Published in:
- PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0036545
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- Publication type:
- Article
Calbindin 2 (CALB2) Regulates 5-Fluorouracil Sensitivity in Colorectal Cancer by Modulating the Intrinsic Apoptotic Pathway.
- Published in:
- PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0020276
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- Publication type:
- Article
A revised model of TRAIL‐R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis.
- Published in:
- EMBO Reports, 2020, v. 21, n. 3, p. 1, doi. 10.15252/embr.201949254
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- Publication type:
- Article
Correction: Hamilton et al. Therapeutics Targeting the Core Apoptotic Machinery. Cancers 2021, 13 , 2618.
- Published in:
- 2022
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- Publication type:
- Correction Notice
Therapeutics Targeting the Core Apoptotic Machinery.
- Published in:
- Cancers, 2021, v. 13, n. 11, p. 2618, doi. 10.3390/cancers13112618
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- Publication type:
- Article
Editor Profile: Daniel Longley.
- Published in:
- FEBS Journal, 2024, v. 291, n. 3, p. 399, doi. 10.1111/febs.16898
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- Publication type:
- Article
Development of a protein signature to enable clinical positioning of IAP inhibitors in colorectal cancer.
- Published in:
- FEBS Journal, 2021, v. 288, n. 18, p. 5374, doi. 10.1111/febs.15801
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- Publication type:
- Article
FLIP(L): the pseudo‐caspase.
- Published in:
- FEBS Journal, 2020, v. 287, n. 19, p. 4246, doi. 10.1111/febs.15260
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- Publication type:
- Article
FLIP as a therapeutic target in cancer.
- Published in:
- FEBS Journal, 2018, v. 285, n. 22, p. 4104, doi. 10.1111/febs.14523
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- Publication type:
- Article
Efficient Drug Delivery and Induction of Apoptosis in Colorectal Tumors Using a Death Receptor 5-Targeted Nanomedicine.
- Published in:
- Molecular Therapy, 2014, v. 22, n. 12, p. 2083, doi. 10.1038/mt.2014.137
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- Publication type:
- Article
USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF.
- Published in:
- Clinical & Translational Medicine, 2024, v. 14, n. 4, p. 1, doi. 10.1002/ctm2.1648
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- Publication type:
- Article
Cancer-cell intrinsic gene expression signatures overcome intratumoural heterogeneity bias in colorectal cancer patient classification.
- Published in:
- Nature Communications, 2017, v. 8, n. 5, p. 15657, doi. 10.1038/ncomms15657
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- Publication type:
- Article
The E3 ubiquitin ligase Itch regulates death receptor and cholesterol trafficking to affect TRAIL-mediated apoptosis.
- Published in:
- Cell Death & Disease, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41419-023-06417-4
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- Publication type:
- Article
Molecular subtype-specific responses of colon cancer cells to the SMAC mimetic Birinapant.
- Published in:
- Cell Death & Disease, 2020, v. 11, n. 11, p. 1, doi. 10.1038/s41419-020-03232-z
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- Publication type:
- Article
RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer.
- Published in:
- Cell Death & Disease, 2020, v. 11, n. 10, p. 1, doi. 10.1038/s41419-020-03131-3
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- Publication type:
- Article
Cytoplasmic FLIP(S) and nuclear FLIP(L) mediate resistance of castrate-resistant prostate cancer to apoptosis induced by IAP antagonists.
- Published in:
- Cell Death & Disease, 2018, v. 9, n. 11, p. 1, doi. 10.1038/s41419-018-1125-5
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- Publication type:
- Article
Identification of unique rectal cancer-specific subtypes.
- Published in:
- British Journal of Cancer, 2024, v. 130, n. 11, p. 1809, doi. 10.1038/s41416-024-02656-0
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- Publication type:
- Article
Controlled coupling of an ultrapotent auristatin warhead to cetuximab yields a next-generation antibody-drug conjugate for EGFR-targeted therapy of KRAS mutant pancreatic cancer.
- Published in:
- 2020
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- Publication type:
- journal article
Pevonedistat (MLN4924): mechanism of cell death induction and therapeutic potential in colorectal cancer.
- Published in:
- Cell Death Discovery, 2020, v. 6, n. 1, p. 1, doi. 10.1038/s41420-020-00296-w
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- Publication type:
- Article
Prognostic and therapeutic relevance of c- FLIP in acute myeloid leukaemia.
- Published in:
- British Journal of Haematology, 2013, v. 160, n. 2, p. 188, doi. 10.1111/bjh.12108
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- Publication type:
- Article
Increased Fusobacterium tumoural abundance affects immunogenicity in mucinous colorectal cancer and may be associated with improved clinical outcome.
- Published in:
- Journal of Molecular Medicine, 2023, v. 101, n. 7, p. 829, doi. 10.1007/s00109-023-02324-5
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- Publication type:
- Article
classifieR a flexible interactive cloud-application for functional annotation of cancer transcriptomes.
- Published in:
- BMC Bioinformatics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12859-022-04641-x
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- Publication type:
- Article
Heterogeneous responses to low level death receptor activation are explained by random molecular assembly of the Caspase-8 activation platform.
- Published in:
- PLoS Computational Biology, 2019, v. 15, n. 9, p. 1, doi. 10.1371/journal.pcbi.1007374
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- Publication type:
- Article
Cancer drug resistance: an evolving paradigm.
- Published in:
- Nature Reviews Cancer, 2013, v. 13, n. 10, p. 714, doi. 10.1038/nrc3599
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- Publication type:
- Article
5-Fluorouracil: mechanisms of action and clinical strategies.
- Published in:
- Nature Reviews Cancer, 2003, v. 3, n. 5, p. 330, doi. 10.1038/nrc1074
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- Publication type:
- Article
surviveR: a flexible shiny application for patient survival analysis.
- Published in:
- 2023
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- Publication type:
- Product Review
The Colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information.
- Published in:
- BMC Cancer, 2010, v. 10, p. 687, doi. 10.1186/1471-2407-10-687
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- Publication type:
- Article
Voltage dependent anion channel-1 regulatesdeath receptor mediated apoptosis by enablingcleavage of caspase-8.
- Published in:
- BMC Cancer, 2010, v. 10, p. 380, doi. 10.1186/1471-2407-10-380
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- Publication type:
- Article