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From bench to bedside: Improving the clinical safety of GalNAc–siRNA conjugates using seed-pairing destabilization.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6656, doi. 10.1093/nar/gkac539
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- Article
dual-activity topoisomerase complex regulates mRNA translation and turnover.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7013, doi. 10.1093/nar/gkac538
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Ribodysgenesis: sudden genome instability in the yeast Saccharomyces cerevisiae arising from RNase H2 cleavage at genomic-embedded ribonucleotides.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6890, doi. 10.1093/nar/gkac536
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Structural and dynamic studies of DNA recognition by NF-κB p50 RHR homodimer using methyl NMR spectroscopy.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7147, doi. 10.1093/nar/gkac535
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H3K36me2 methyltransferase NSD2 orchestrates epigenetic reprogramming during spermatogenesis.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6786, doi. 10.1093/nar/gkac533
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Identification of flexible Pif1–DNA interactions and their impacts on enzymatic activities.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7002, doi. 10.1093/nar/gkac529
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HSP90 and Aha1 modulate microRNA maturation through promoting the folding of Dicer1.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6990, doi. 10.1093/nar/gkac528
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DNA G-quadruplex structure participates in regulation of lipid metabolism through acyl-CoA binding protein.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6953, doi. 10.1093/nar/gkac527
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LncRNA OIP5-AS1-directed miR-7 degradation promotes MYMX production during human myogenesis.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7115, doi. 10.1093/nar/gkac524
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G-quadruplex structure of the C. elegans telomeric repeat: a two tetrads basket type conformation stabilized by a non-canonical C–T base-pair.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7134, doi. 10.1093/nar/gkac523
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Torsional behaviour of supercoiled DNA regulates recognition of architectural protein Fis on minicircle DNA.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6671, doi. 10.1093/nar/gkac522
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Migrating bubble synthesis promotes mutagenesis through lesions in its template.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6870, doi. 10.1093/nar/gkac520
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Anatomy of four human Argonaute proteins.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6618, doi. 10.1093/nar/gkac519
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Direct tracking of reverse-transcriptase speed and template sensitivity: implications for sequencing and analysis of long RNA molecules.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6980, doi. 10.1093/nar/gkac518
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Host cell RecA activates a mobile element-encoded mutagenic DNA polymerase.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6854, doi. 10.1093/nar/gkac515
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cotranscriptional folding landscape for two cyclic di-nucleotide-sensing riboswitches with highly homologous aptamer domains acting either as ON- or OFF-switches.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6639, doi. 10.1093/nar/gkac514
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Body temperature variation controls pre-mRNA processing and transcription of antiviral genes and SARS-CoV-2 replication.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6769, doi. 10.1093/nar/gkac513
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TRIM25 inhibits influenza A virus infection, destabilizes viral mRNA, but is redundant for activating the RIG-I pathway.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7097, doi. 10.1093/nar/gkac512
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Correction to 'Effects of chain length and geometry on the activation of DNA damage bypass by polyubiquitylated PCNA' and 'Structural basis of ubiquitin recognition by the winged-helix domain of Cockayne syndrome group B protein'.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7197, doi. 10.1093/nar/gkac507
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- Article
Decoding phage resistance by mpr and its role in survivability of Mycobacterium smegmatis.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6938, doi. 10.1093/nar/gkac505
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Synthesis of the NarP response regulator of nitrate respiration in Escherichia coli is regulated at multiple levels by Hfq and small RNAs.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6753, doi. 10.1093/nar/gkac504
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Tissue- and ethnicity-independent hypervariable DNA methylation states show evidence of establishment in the early human embryo.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6735, doi. 10.1093/nar/gkac503
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new bacterial tRNA enhances antibiotic production in Streptomyces by circumventing inefficient wobble base-pairing.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7084, doi. 10.1093/nar/gkac502
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AtNusG, a chloroplast nucleoid protein of bacterial origin linking chloroplast transcriptional and translational machineries, is required for proper chloroplast gene expression in Arabidopsis thaliana.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6715, doi. 10.1093/nar/gkac501
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Drosophila hnRNP F/H homolog Glorund recruits dFMRP to inhibit nanos translation elongation.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7067, doi. 10.1093/nar/gkac500
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PUMILIO competes with AUF1 to control DICER1 RNA levels and miRNA processing.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7048, doi. 10.1093/nar/gkac499
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Mechanism of lesion verification by the human XPD helicase in nucleotide excision repair.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6837, doi. 10.1093/nar/gkac496
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Experimental paradigms revisited: oxidative stress-induced tRNA fragmentation does not correlate with stress granule formation but is associated with delayed cell death.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6919, doi. 10.1093/nar/gkac495
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Ep300 sequestration to functionally distinct glucocorticoid receptor binding loci underlie rapid gene activation and repression.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6702, doi. 10.1093/nar/gkac488
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dsRBP Staufen2 governs RNP assembly of neuronal Argonaute proteins.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7034, doi. 10.1093/nar/gkac487
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TWIST1 methylation by SETD6 selectively antagonizes LINC-PINT expression in glioma.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6903, doi. 10.1093/nar/gkac485
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Controllable assembly of synthetic constructs with programmable ternary DNA interaction.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7188, doi. 10.1093/nar/gkac478
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Insights into the product release mechanism of dengue virus NS3 helicase.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6968, doi. 10.1093/nar/gkac473
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Utilizing RNA origami scaffolds in Saccharomyces cerevisiae for dCas9-mediated transcriptional control.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 7176, doi. 10.1093/nar/gkac470
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TEB/POLQ plays dual roles in protecting Arabidopsis from NO-induced DNA damage.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6820, doi. 10.1093/nar/gkac469
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Genome-wide CRISPR/Cas9 transcriptional activation screen identifies a histone acetyltransferase inhibitor complex as a regulator of HIV-1 integration.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6687, doi. 10.1093/nar/gkac464
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Joint dimension reduction and clustering analysis of single-cell RNA-seq and spatial transcriptomics data.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. e72, doi. 10.1093/nar/gkac219
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MarcoPolo: a method to discover differentially expressed genes in single-cell RNA-seq data without depending on prior clustering.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. e71, doi. 10.1093/nar/gkac216
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EPIMUTESTR: a nearest neighbor machine learning approach to predict cancer driver genes from the evolutionary action of coding variants.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. e70, doi. 10.1093/nar/gkac215
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Optical control of protein delivery and partitioning in the nucleolus.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. e69, doi. 10.1093/nar/gkac191
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Stitchr: stitching coding TCR nucleotide sequences from V/J/CDR3 information.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. e68, doi. 10.1093/nar/gkac190
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Expanding the DNA-encoded library toolbox: identifying small molecules targeting RNA.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. e67, doi. 10.1093/nar/gkac173
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Deficiency of ribosomal proteins reshapes the transcriptional and translational landscape in human cells.
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- Nucleic Acids Research, 2022, v. 50, n. 12, p. 6601, doi. 10.1093/nar/gkac053
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