Works matching IS 03051048 AND DT 2022 AND VI 50 AND IP 4

Results: 45

Flexible TALEs for an expanded use in gene activation, virulence and scaffold engineering.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2387, doi. 10.1093/nar/gkac098

By:

Becker, Sebastian;
Mücke, Stefanie;
Grau, Jan;
Boch, Jens

Publication type:

Article

DNA methylation cues in nucleosome geometry, stability and unwrapping.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1864, doi. 10.1093/nar/gkac097

By:

Li, Shuxiang;
Peng, Yunhui;
Landsman, David;
Panchenko, Anna R

Publication type:

Article

Origin of life: protoribosome forms peptide bonds and links RNA and protein dominated worlds.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1815, doi. 10.1093/nar/gkac052

By:

Bose, Tanaya;
Fridkin, Gil;
Davidovich, Chen;
Krupkin, Miri;
Dinger, Nikita;
Falkovich, Alla H;
Peleg, Yoav;
Agmon, Ilana;
Bashan, Anat;
Yonath, Ada

Publication type:

Article

Loss of histone methyltransferase SETD1B in oogenesis results in the redistribution of genomic histone 3 lysine 4 trimethylation.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1993, doi. 10.1093/nar/gkac051

By:

Hanna, Courtney W;
Huang, Jiahao;
Belton, Christian;
Reinhardt, Susanne;
Dahl, Andreas;
Andrews, Simon;
Stewart, A Francis;
Kranz, Andrea;
Kelsey, Gavin

Publication type:

Article

Structural effects of m6A modification of the Xist A-repeat AUCG tetraloop and its recognition by YTHDC1.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2350, doi. 10.1093/nar/gkac080

By:

Jones, Alisha N;
Tikhaia, Ekaterina;
Mourão, André;
Sattler, Michael

Publication type:

Article

structure of AcrIE4-F7 reveals a common strategy for dual CRISPR inhibition by targeting PAM recognition sites.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2363, doi. 10.1093/nar/gkac096

By:

Hong, Sung-Hyun;
Lee, Gyujin;
Park, Changkon;
Koo, Jasung;
Kim, Eun-Hee;
Bae, Euiyoung;
Suh, Jeong-Yong

Publication type:

Article

Elongation factor TFIIS is essential for heat stress adaptation in plants.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1927, doi. 10.1093/nar/gkac020

By:

Szádeczky-Kardoss, István;
Szaker, Henrik Mihály;
Verma, Radhika;
Darkó, Éva;
Pettkó-Szandtner, Aladár;
Silhavy, Dániel;
Csorba, Tibor

Publication type:

Article

Endogenous retroviruses co-opted as divergently transcribed regulatory elements shape the regulatory landscape of embryonic stem cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2111, doi. 10.1093/nar/gkac088

By:

Bakoulis, Stylianos;
Krautz, Robert;
Alcaraz, Nicolas;
Salvatore, Marco;
Andersson, Robin

Publication type:

Article

Rational design of small-molecules to recognize G-quadruplexes of c-MYC promoter and telomere and the evaluation of their in vivo antitumor activity against breast cancer.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1829, doi. 10.1093/nar/gkac090

By:

Long, Wei;
Zheng, Bo-Xin;
Li, Ying;
Huang, Xuan-He;
Lin, Dan-Min;
Chen, Cui-Cui;
Hou, Jin-Qiang;
Ou, Tian-Miao;
Wong, Wing-Leung;
Zhang, Kun;
Lu, Yu-Jing

Publication type:

Article

Physical ARTEMIS:DNA-PKcs interaction is necessary for V(D)J recombination.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2096, doi. 10.1093/nar/gkac071

By:

Niewolik, Doris;
Schwarz, Klaus

Publication type:

Article

interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2172, doi. 10.1093/nar/gkac086

By:

Abel, Yoann;
Charron, Christophe;
Virciglio, Camille;
Bourguignon-Igel, Valérie;
Quinternet, Marc;
Chagot, Marie-Eve;
Robert, Marie-Cécile;
Verheggen, Céline;
Branlant, Christiane;
Bertrand, Edouard;
Manival, Xavier;
Charpentier, Bruno;
Rederstorff, Mathieu

Publication type:

Article

transcriptional elongation factor CTR9 demarcates PRC2-mediated H3K27me3 domains by altering PRC2 subtype equilibrium.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1969, doi. 10.1093/nar/gkac047

By:

Chan, Ngai Ting;
Huang, Junfeng;
Ma, Gui;
Zeng, Hao;
Donahue, Kristine;
Wang, Yidan;
Li, Lingjun;
Xu, Wei

Publication type:

Article

High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X protein.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2157, doi. 10.1093/nar/gkac070

By:

Shen, Zhongliang;
Wu, Jingwen;
Gao, Zixiang;
Zhang, Shenyan;
Chen, Jingwen;
He, Jingjing;
Guo, Yifei;
Deng, Qiang;
Xie, Youhua;
Liu, Jing;
Zhang, Jiming

Publication type:

Article

Transcription-replication coordination revealed in single live cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2143, doi. 10.1093/nar/gkac069

By:

Tsirkas, Ioannis;
Dovrat, Daniel;
Thangaraj, Manikandan;
Brouwer, Ineke;
Cohen, Amit;
Paleiov, Zohar;
Meijler, Michael M;
Lenstra, Tineke;
Aharoni, Amir

Publication type:

Article

Synthetic robust perfect adaptation achieved by negative feedback coupling with linear weak positive feedback.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2377, doi. 10.1093/nar/gkac066

By:

Sun, Zhi;
Wei, Weijia;
Zhang, Mingyue;
Shi, Wenjia;
Zong, Yeqing;
Chen, Yihua;
Yang, Xiaojing;
Yu, Bo;
Tang, Chao;
Lou, Chunbo

Publication type:

Article

non-telomeric evolutionary trajectory of TRF2 in zebrafish reveals its specific roles in neurodevelopment and aging.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2081, doi. 10.1093/nar/gkac065

By:

Ying, Yilin;
Hu, Xuefei;
Han, Peng;
Mendez-Bermudez, Aaron;
Bauwens, Serge;
Eid, Rita;
Tan, Li;
Pousse, Mélanie;
Giraud-Panis, Marie-Joseph;
Lu, Yiming;
Gilson, Eric;
Ye, Jing

Publication type:

Article

Epitranscriptomic regulation of HIV-1 full-length RNA packaging.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2302, doi. 10.1093/nar/gkac062

By:

Pereira-Montecinos, Camila;
Toro-Ascuy, Daniela;
Ananías-Sáez, Catarina;
Gaete-Argel, Aracelly;
Rojas-Fuentes, Cecilia;
Riquelme-Barrios, Sebastián;
Rojas-Araya, Bárbara;
García-de-Gracia, Francisco;
Aguilera-Cortés, Paulina;
Chnaiderman, Jonás;
Acevedo, Mónica L;
Valiente-Echeverría, Fernando;
Soto-Rifo, Ricardo

Publication type:

Article

low-resolution structural models of hepatitis C virus RNA subdomain 5BSL3.2 and its distal complex with domain 3′X point to conserved regulatory mechanisms within the Flaviviridae family.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2287, doi. 10.1093/nar/gkac061

By:

Castillo-Martínez, Jesús;
Fan, Lixin;
Szewczyk, Mateusz P;
Wang, Yun-Xing;
Gallego, José

Publication type:

Article

Sal-type ABC-F proteins: intrinsic and common mediators of pleuromutilin resistance by target protection in staphylococci.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2128, doi. 10.1093/nar/gkac058

By:

Mohamad, Merianne;
Nicholson, David;
Saha, Chayan Kumar;
Hauryliuk, Vasili;
Edwards, Thomas A;
Atkinson, Gemma C;
Ranson, Neil A;
O'Neill, Alex J

Publication type:

Article

Prediction and pan-cancer analysis of mammalian transcripts involved in target directed miRNA degradation.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2019, doi. 10.1093/nar/gkac057

By:

Simeone, Ines;
Rubolino, Carmela;
Noviello, Teresa Maria Rosaria;
Farinello, Diego;
Cerulo, Luigi;
Marzi, Matteo Jacopo;
Nicassio, Francesco

Publication type:

Article

Commonality and diversity in tRNA substrate recognition in t6A biogenesis by eukaryotic KEOPSs.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2223, doi. 10.1093/nar/gkac056

By:

Wang, Jin-Tao;
Zhou, Jing-Bo;
Mao, Xue-Ling;
Zhou, Li;
Chen, Meirong;
Zhang, Wenhua;
Wang, En-Duo;
Zhou, Xiao-Long

Publication type:

Article

RBFOX2 is required for establishing RNA regulatory networks essential for heart development.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2270, doi. 10.1093/nar/gkac055

By:

Verma, Sunil K;
Deshmukh, Vaibhav;
Thatcher, Kaitlyn;
Belanger, KarryAnne K;
Rhyner, Alexander M;
Meng, Shu;
Holcomb, Richard Joshua;
Bressan, Michael;
Martin, James F;
Cooke, John P;
Wythe, Joshua D;
Widen, Steven G;
Lincoln, Joy;
Kuyumcu-Martinez, Muge N

Publication type:

Article

Klf4 methylated by Prmt1 restrains the commitment of primitive endoderm.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2005, doi. 10.1093/nar/gkac054

By:

Zuo, Zhen-yu;
Yang, Guang-hui;
Wang, Hai-yu;
Liu, Shu-yu;
Zhang, Yan-jun;
Cai, Yun;
Chen, Fei;
Dai, Hui;
Xiao, Yi;
Cheng, Mo-bin;
Huang, Yue;
Zhang, Ye

Publication type:

Article

Evolutionary rewiring of regulatory networks contributes to phenotypic differences between human and mouse orthologous genes.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1849, doi. 10.1093/nar/gkac050

By:

Ha, Doyeon;
Kim, Donghyo;
Kim, Inhae;
Oh, Youngchul;
Kong, JungHo;
Han, Seong Kyu;
Kim, Sanguk

Publication type:

Article

Eukaryotic stress–induced mutagenesis is limited by a local control of translesion synthesis.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2074, doi. 10.1093/nar/gkac044

By:

Masłowska, Katarzyna H;
Villafañez, Florencia;
Laureti, Luisa;
Iwai, Shigenori;
Pagès, Vincent

Publication type:

Article

Mechanistic decoupling of exonuclease III multifunctionality into AP endonuclease and exonuclease activities at the single-residue level.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2211, doi. 10.1093/nar/gkac043

By:

Lee, Donghun;
Oh, Sanghoon;
Cho, HyeokJin;
Yoo, Jungmin;
Lee, Gwangrog

Publication type:

Article

Transcription factor Zfp276 drives oligodendroglial differentiation and myelination by switching off the progenitor cell program.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1951, doi. 10.1093/nar/gkac042

By:

Aberle, Tim;
Piefke, Sandra;
Hillgärtner, Simone;
Tamm, Ernst R;
Wegner, Michael;
Küspert, Melanie

Publication type:

Article

RadD is a RecA-dependent accessory protein that accelerates DNA strand exchange.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2201, doi. 10.1093/nar/gkac041

By:

Bonde, Nina J;
Romero, Zachary J;
Chitteni-Pattu, Sindhu;
Cox, Michael M

Publication type:

Article

RNA modifications stabilize the tertiary structure of tRNAfMet by locally increasing conformational dynamics.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2334, doi. 10.1093/nar/gkac040

By:

Biedenbänder, Thomas;
de Jesus, Vanessa;
Schmidt-Dengler, Martina;
Helm, Mark;
Corzilius, Björn;
Fürtig, Boris

Publication type:

Article

Folding of VemP into translation-arresting secondary structure is driven by the ribosome exit tunnel.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2258, doi. 10.1093/nar/gkac038

By:

Kolář, Michal H;
Nagy, Gabor;
Kunkel, John;
Vaiana, Sara M;
Bock, Lars V;
Grubmüller, Helmut

Publication type:

Article

Genomic patterns of transcription–replication interactions in mouse primary B cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2051, doi. 10.1093/nar/gkac035

By:

St Germain, Commodore P;
Zhao, Hongchang;
Sinha, Vrishti;
Sanz, Lionel A;
Chédin, Frédéric;
Barlow, Jacqueline H

Publication type:

Article

Gain of C-Ala enables AlaRS to target the L-shaped tRNAAla.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2190, doi. 10.1093/nar/gkac026

By:

Antika, Titi Rindi;
Chrestella, Dea Jolie;
Ivanesthi, Indira Rizqita;
Rida, Gita Riswana Nawung;
Chen, Kuan-Yu;
Liu, Fu-Guo;
Lee, Yi-Chung;
Chen, Yu-Wei;
Tseng, Yi-Kuan;
Wang, Chien-Chia

Publication type:

Article

POLIE suppresses telomerase-mediated telomere G-strand extension and helps ensure proper telomere C-strand synthesis in trypanosomes.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2036, doi. 10.1093/nar/gkac023

By:

Rabbani, M A G;
Tonini, Maiko Luis;
Afrin, Marjia;
Li, Bibo

Publication type:

Article

Nuclear export restricts Gdown1 to a mitotic function.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1908, doi. 10.1093/nar/gkac015

By:

Ball, Christopher B;
Parida, Mrutyunjaya;
Santana, Juan F;
Spector, Benjamin M;
Suarez, Gustavo A;
Price, David H

Publication type:

Article

Analysis of epigenetic features characteristic of L1 loci expressed in human cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1888, doi. 10.1093/nar/gkac013

By:

Freeman, Benjamin;
White, Travis;
Kaul, Tiffany;
Stow, Emily C;
Baddoo, Melody;
Ungerleider, Nathan;
Morales, Maria;
Yang, Hanlin;
Deharo, Dawn;
Deininger, Prescott;
Belancio, Victoria P

Publication type:

Article

Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2240, doi. 10.1093/nar/gkab606

By:

Hopes, Tayah;
Norris, Karl;
Agapiou, Michaela;
McCarthy, Charley G P;
Lewis, Philip A;
O'Connell, Mary J;
Fontana, Juan;
Aspden, Julie L

Publication type:

Article

Chaperone mediated autophagy contributes to the newly synthesized histones H3 and H4 quality control.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1875, doi. 10.1093/nar/gkab1296

By:

Hormazabal, Juan;
Saavedra, Francisco;
Espinoza-Arratia, Claudia;
Martinez, Nicolas W;
Cruces, Tatiana;
Alfaro, Iván E;
Loyola, Alejandra

Publication type:

Article

Phospho-RNA sequencing with circAID-p-seq.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. e23, doi. 10.1093/nar/gkab1158

By:

Del Piano, Alessia;
Kecman, Tea;
Schmid, Michael;
Barbieri, Ruggero;
Brocchieri, Luciano;
Tornaletti, Silvia;
Firrito, Claudia;
Minati, Luca;
Bernabo, Paola;
Signoria, Ilaria;
Lauria, Fabio;
Gillingwater, Thomas H;
Viero, Gabriella;
Clamer, Massimiliano

Publication type:

Article

Role of PemI in the Staphylococcus aureus PemIK toxin–antitoxin complex: PemI controls PemK by acting as a PemK loop mimic.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 2319, doi. 10.1093/nar/gkab1288

By:

Kim, Do-Hee;
Kang, Sung-Min;
Baek, Sung-Min;
Yoon, Hye-Jin;
Jang, Dong Man;
Kim, Hyoun Sook;
Lee, Sang Jae;
Lee, Bong-Jin

Publication type:

Article

OUHP: an optimized universal hairpin primer system for cost-effective and high-throughput RT-qPCR-based quantification of microRNA (miRNA) expression.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. e22, doi. 10.1093/nar/gkab1153

By:

He, Fang;
Ni, Na;
Wang, Hao;
Zeng, Zongyue;
Zhao, Piao;
Shi, Deyao;
Xia, Yinglin;
Chen, Connie;
Hu, Daniel A;
Qin, Kevin H;
Wagstaff, William;
Qin, David;
Hendren-Santiago, Bryce;
Ho, Sherwin H;
Haydon, Rex C;
Luu, Hue H;
Reid, Russell R;
Shen, Le;
Gan, Hua;
Fan, Jiaming

Publication type:

Article

Analysis of subcellular transcriptomes by RNA proximity labeling with Halo-seq.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. e24, doi. 10.1093/nar/gkab1185

By:

Engel, Krysta L;
Lo, Hei-Yong G;
Goering, Raeann;
Li, Ying;
Spitale, Robert C;
Taliaferro, J Matthew

Publication type:

Article

Effective and scalable single-cell data alignment with non-linear canonical correlation analysis.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. e21, doi. 10.1093/nar/gkab1147

By:

Hu, Jialu;
Chen, Mengjie;
Zhou, Xiang

Publication type:

Article

CRISPRroots: on- and off-target assessment of RNA-seq data in CRISPR–Cas9 edited cells.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. e20, doi. 10.1093/nar/gkab1131

By:

Corsi, Giulia I;
Gadekar, Veerendra P;
Gorodkin, Jan;
Seemann, Stefan E

Publication type:

Article

RNase H is an exo- and endoribonuclease with asymmetric directionality, depending on the binding mode to the structural variants of RNA:DNA hybrids.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. 1801, doi. 10.1093/nar/gkab1064

By:

Lee, Hyunjee;
Cho, HyeokJin;
Kim, Jooyoung;
Lee, Sua;
Yoo, Jungmin;
Park, Daeho;
Lee, Gwangrog

Publication type:

Article

Accurate expression quantification from nanopore direct RNA sequencing with NanoCount.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 4, p. e19, doi. 10.1093/nar/gkab1129

By:

Gleeson, Josie;
Leger, Adrien;
Prawer, Yair D J;
Lane, Tracy A;
Harrison, Paul J;
Haerty, Wilfried;
Clark, Michael B

Publication type:

Article