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Crystal structures of alphavirus nonstructural protein 4 (nsP4) reveal an intrinsically dynamic RNA-dependent RNA polymerase fold.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1000, doi. 10.1093/nar/gkab1302
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- Article
Dissection of nanoconfinement and proximity effects on the binding events in DNA origami nanocavity.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 697, doi. 10.1093/nar/gkab1298
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- Article
Integration of single cell data by disentangled representation learning.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. e8, doi. 10.1093/nar/gkab978
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scMRMA: single cell multiresolution marker-based annotation.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. e7, doi. 10.1093/nar/gkab931
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Directed evolution of orthogonal RNA–RBP pairs through library-vs-library in vitro selection.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 601, doi. 10.1093/nar/gkab527
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HI-NESS: a family of genetically encoded DNA labels based on a bacterial nucleoid-associated protein.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. e10, doi. 10.1093/nar/gkab993
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High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. e9, doi. 10.1093/nar/gkab989
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Comprehensive analysis of prime editing outcomes in human embryonic stem cells.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1187, doi. 10.1093/nar/gkab1295
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Editorial Expression of Concern on 'Protein kinase CK2 phosphorylation regulates the interaction of Kaposi's sarcoma-associated herpesvirus regulatory protein ORF57 with its multifunctional partner hnRNP K'.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1200, doi. 10.1093/nar/gkab1294
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- Article
Systematic characterization of short intronic splicing-regulatory elements in SMN2 pre-mRNA.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 731, doi. 10.1093/nar/gkab1280
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Correction to 'Fail-safe genetic codes designed to intrinsically contain engineered organisms'.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1199, doi. 10.1093/nar/gkab1285
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Correction to 'MoiRNAiFold: a novel tool for complex in silico RNA design'.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1198, doi. 10.1093/nar/gkab1284
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Nonalternating purine pyrimidine sequences can form stable left-handed DNA duplex by strong topological constraint.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 684, doi. 10.1093/nar/gkab1283
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nucleotide messenger (p)ppGpp is an anti-inducer of the purine synthesis transcription regulator PurR in Bacillus.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 847, doi. 10.1093/nar/gkab1281
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- Article
Ribosomal leaky scanning through a translated uORF requires eIF4G2.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1111, doi. 10.1093/nar/gkab1286
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- Article
Coronaviral RNA-methyltransferases: function, structure and inhibition.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 635, doi. 10.1093/nar/gkab1279
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Structural and biochemical characterization of human Schlafen 5.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1147, doi. 10.1093/nar/gkab1278
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Metallohelix vectors for efficient gene delivery via cationic DNA nanoparticles.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 674, doi. 10.1093/nar/gkab1277
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CryoEM of RUVBL1–RUVBL2–ZNHIT2, a complex that interacts with pre-mRNA-processing-splicing factor 8.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1128, doi. 10.1093/nar/gkab1267
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Impaired function of rDNA transcription initiation machinery leads to derepression of ribosomal genes with insertions of R2 retrotransposon.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 867, doi. 10.1093/nar/gkab1276
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H2A mono-ubiquitination differentiates FACT's functions in nucleosome assembly and disassembly.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 833, doi. 10.1093/nar/gkab1271
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Structure–activity relationships at a nucleobase-stacking tryptophan required for chemomechanical coupling in the DNA resecting motor-nuclease AdnAB.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 952, doi. 10.1093/nar/gkab1270
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Genomic landscape of single-stranded DNA gapped intermediates in Escherichia coli.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 937, doi. 10.1093/nar/gkab1269
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Condensin extrudes DNA loops in steps up to hundreds of base pairs that are generated by ATP binding events.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 820, doi. 10.1093/nar/gkab1268
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"Bind, cleave and leave": multiple turnover catalysis of RNA cleavage by bulge–loop inducing supramolecular conjugates.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 651, doi. 10.1093/nar/gkab1273
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Genetic screen for suppression of transcriptional interference reveals fission yeast 14–3–3 protein Rad24 as an antagonist of precocious Pol2 transcription termination.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 803, doi. 10.1093/nar/gkab1263
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interaction between the Spt6-tSH2 domain and Rpb1 affects multiple functions of RNA Polymerase II.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 784, doi. 10.1093/nar/gkab1262
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Determinants of the temperature adaptation of mRNA degradation.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1092, doi. 10.1093/nar/gkab1261
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Stimulation of adaptive gene amplification by origin firing under replication fork constraint.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 915, doi. 10.1093/nar/gkab1257
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Reexamining assumptions about miRNA-guided gene silencing.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 617, doi. 10.1093/nar/gkab1256
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Probing the mechanisms of two exonuclease domain mutators of DNA polymerase ϵ.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 962, doi. 10.1093/nar/gkab1255
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Redirecting meiotic DNA break hotspot determinant proteins alters localized spatial control of DNA break formation and repair.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 899, doi. 10.1093/nar/gkab1253
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Ribonucleotides embedded in template DNA impair mitochondrial RNA polymerase progression.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 989, doi. 10.1093/nar/gkab1251
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Hox transcription factor Ultrabithorax binds RNA and regulates co-transcriptional splicing through an interplay with RNA polymerase II.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 763, doi. 10.1093/nar/gkab1250
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Regulation of AR mRNA translation in response to acute AR pathway inhibition.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1069, doi. 10.1093/nar/gkab1247
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Computational investigation of the impact of core sequence on immobile DNA four-way junction structure and dynamics.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 717, doi. 10.1093/nar/gkab1246
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Horizontal gene transfer as a mechanism for the promiscuous acquisition of distinct classes of IRES by avian caliciviruses.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1052, doi. 10.1093/nar/gkab1243
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Pairing of single mutations yields obligate Cre-type site-specific recombinases.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1174, doi. 10.1093/nar/gkab1240
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CCPE: cell cycle pseudotime estimation for single cell RNA-seq data.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 704, doi. 10.1093/nar/gkab1236
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Early rRNA processing is a stress-dependent regulatory event whose inhibition maintains nucleolar integrity.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1033, doi. 10.1093/nar/gkab1231
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Disrupting the Cdk9/Cyclin T1 heterodimer of 7SK snRNP for the Brd4 and AFF1/4 guided reconstitution of active P-TEFb.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 750, doi. 10.1093/nar/gkab1228
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Efficient target cleavage by Type V Cas12a effectors programmed with split CRISPR RNA.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1162, doi. 10.1093/nar/gkab1227
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Highly conserved s2m element of SARS-CoV-2 dimerizes via a kissing complex and interacts with host miRNA-1307-3p.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 1017, doi. 10.1093/nar/gkab1226
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Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 885, doi. 10.1093/nar/gkab1223
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epigenetic switch activates bacterial quorum sensing and horizontal transfer of an integrative and conjugative element.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. 975, doi. 10.1093/nar/gkab1217
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Enhancing biological signals and detection rates in single-cell RNA-seq experiments with cDNA library equalization.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. e12, doi. 10.1093/nar/gkab1071
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Uncertainty-aware and interpretable evaluation of Cas9–gRNA and Cas12a–gRNA specificity for fully matched and partially mismatched targets with Deep Kernel Learning.
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- Nucleic Acids Research, 2022, v. 50, n. 2, p. e11, doi. 10.1093/nar/gkab1065
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