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Site-specific incorporation of 5′-methyl DNA enhances the therapeutic profile of gapmer ASOs.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1828, doi. 10.1093/nar/gkab047
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Structural basis of diversity and homodimerization specificity of zinc-finger-associated domains in Drosophila.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2375, doi. 10.1093/nar/gkab061
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- Article
Oxidative lesions modulate G-quadruplex stability and structure in the human BCL2 promoter.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2346, doi. 10.1093/nar/gkab057
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CK2 kinase-mediated PHF8 phosphorylation controls TopBP1 stability to regulate DNA replication.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2400, doi. 10.1093/nar/gkab056
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Small-molecule inhibitors of histone deacetylase improve CRISPR-based adenine base editing.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2390, doi. 10.1093/nar/gkab052
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A unique arginine cluster in PolDIP2 enhances nucleotide binding and DNA synthesis by PrimPol.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2179, doi. 10.1093/nar/gkab049
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Structure-based analyses of Salmonella RcsB variants unravel new features of the Rcs regulon.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2357, doi. 10.1093/nar/gkab060
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A native, highly active Tc1/mariner transposon from zebrafish (ZB) offers an efficient genetic manipulation tool for vertebrates.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2126, doi. 10.1093/nar/gkab045
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Mechanism of DNA cleavage by the endonuclease SauUSI: a major barrier to horizontal gene transfer and antibiotic resistance in Staphylococcus aureus.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2161, doi. 10.1093/nar/gkab042
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Human Rev1 relies on insert-2 to promote selective binding and accurate replication of stabilized G-quadruplex motifs.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2065, doi. 10.1093/nar/gkab041
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DNA G-quadruplexes for native mass spectrometry in potassium: a database of validated structures in electrospray-compatible conditions.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2333, doi. 10.1093/nar/gkab039
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Overlapping but distinct: a new model for G-quadruplex biochemical specificity.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1816, doi. 10.1093/nar/gkab037
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BACH1 recruits NANOG and histone H3 lysine 4 methyltransferase MLL/SET1 complexes to regulate enhancer–promoter activity and maintains pluripotency.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1972, doi. 10.1093/nar/gkab034
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SUMOylation regulates the protein network and chromatin accessibility at glucocorticoid receptor-binding sites.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1951, doi. 10.1093/nar/gkab032
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PAUPAR and PAX6 sequentially regulate human embryonic stem cell cortical differentiation.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1935, doi. 10.1093/nar/gkab030
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Insight into formation propensity of pseudocircular DNA G-hairpins.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2317, doi. 10.1093/nar/gkab029
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Dynamics of the HD regulatory subdomain of PARP-1; substrate access and allostery in PARP activation and inhibition.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2266, doi. 10.1093/nar/gkab020
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NMR structural study on the self-trimerization of d(GTTAGG) into a dynamic trimolecular G-quadruplex assembly preferentially in Na<sup>+</sup> solution with a moderate K<sup>+</sup> tolerance.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2306, doi. 10.1093/nar/gkab028
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Structure of a reaction intermediate mimic in t<sup>6</sup>A biosynthesis bound in the active site of the TsaBD heterodimer from Escherichia coli.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2141, doi. 10.1093/nar/gkab026
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Non-perfectly matching small RNAs can induce stable and heritable epigenetic modifications and can be used as molecular markers to trace the origin and fate of silencing RNAs.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1900, doi. 10.1093/nar/gkab023
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Targeted splice sequencing reveals RNA toxicity and therapeutic response in myotonic dystrophy.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2240, doi. 10.1093/nar/gkab022
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In vitro selected GUAA tetraloop-binding receptors with structural plasticity and evolvability towards natural RNA structural modules.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2289, doi. 10.1093/nar/gkab021
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Repression of a large number of genes requires interplay between homologous recombination and HIRA.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1914, doi. 10.1093/nar/gkab027
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Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2044, doi. 10.1093/nar/gkab019
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Hibernation factors directly block ribonucleases from entering the ribosome in response to starvation.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2226, doi. 10.1093/nar/gkab017
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Dinucleotides as simple models of the base stacking-unstacking component of DNA 'breathing' mechanisms.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1872, doi. 10.1093/nar/gkab015
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The metabolite methylglyoxal-mediated gene expression is associated with histone methylglyoxalation.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1886, doi. 10.1093/nar/gkab014
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Human pathways in animal models: possibilities and limitations.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1859, doi. 10.1093/nar/gkab012
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Anatomy of noncovalent interactions between the nucleobases or ribose and π-containing amino acids in RNA–protein complexes.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2213, doi. 10.1093/nar/gkab008
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A heme•DNAzyme activated by hydrogen peroxide catalytically oxidizes thioethers by direct oxygen atom transfer rather than by a Compound I-like intermediate.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1803, doi. 10.1093/nar/gkab007
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Mobile element warfare via CRISPR and anti-CRISPR in Pseudomonas aeruginosa.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2114, doi. 10.1093/nar/gkab006
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The nascent polypeptide in the 60S subunit determines the Rqc2-dependency of ribosomal quality control.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2102, doi. 10.1093/nar/gkab005
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Prpf31 is essential for the survival and differentiation of retinal progenitor cells by modulating alternative splicing.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2027, doi. 10.1093/nar/gkab003
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CoBold: a method for identifying different functional classes of transient RNA structure features that can impact RNA structure formation in vivo.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. e19, doi. 10.1093/nar/gkaa900
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RPA complexes in Caenorhabditis elegans meiosis; unique roles in replication, meiotic recombination and apoptosis.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2005, doi. 10.1093/nar/gkaa1293
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MazF toxin causes alterations in Staphylococcus aureus transcriptome, translatome and proteome that underlie bacterial dormancy.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2085, doi. 10.1093/nar/gkaa1292
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Allosteric effects of SSB C-terminal tail on assembly of E. coli RecOR proteins.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1987, doi. 10.1093/nar/gkaa1291
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Structural determinants of the IRF4/DNA homodimeric complex.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2255, doi. 10.1093/nar/gkaa1287
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Another layer of complexity in Staphylococcus aureus methionine biosynthesis control: unusual RNase III-driven T-box riboswitch cleavage determines met operon mRNA stability and decay.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 2192, doi. 10.1093/nar/gkaa1277
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Polymer modelling unveils the roles of heterochromatin and nucleolar organizing regions in shaping 3D genome organization in Arabidopsis thaliana.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. 1840, doi. 10.1093/nar/gkaa1275
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NGS-based identification and tracing of microsatellite instability from minute amounts DNA using inter-Alu-PCR.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. e24, doi. 10.1093/nar/gkaa1175
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NOseq: amplicon sequencing evaluation method for RNA m<sup>6</sup>A sites after chemical deamination.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. e23, doi. 10.1093/nar/gkaa1173
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The CONJUDOR pipeline for multiplexed knockdown of gene pairs identifies RBBP-5 as a germ cell reprogramming barrier in C. elegans.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. e22, doi. 10.1093/nar/gkaa1171
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Alignment free identification of clones in B cell receptor repertoires.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. e21, doi. 10.1093/nar/gkaa1160
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CRISPRidentify: identification of CRISPR arrays using machine learning approach.
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- Nucleic Acids Research, 2021, v. 49, n. 4, p. e20, doi. 10.1093/nar/gkaa1158
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