Works matching IS 02678357 AND DT 2016 AND VI 31 AND IP 3
Results: 14
A proposal for a novel rationale for critical effect size in dose--response analysis based on a multi-endpoint in vivo study with methyl methanesulfonate.
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- Mutagenesis, 2016, v. 31, n. 3, p. 239, doi. 10.1093/mutage/gev077
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Empirical analysis of BMD metrics in genetic toxicology part II: in vivo potency comparisons to promote reductions in the use of experimental animals for genetic toxicity assessment.
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- Mutagenesis, 2016, v. 31, n. 3, p. 265, doi. 10.1093/mutage/gew009
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Empirical analysis of BMD metrics in genetic toxicology part I: in vitro analyses to provide robust potency rankings and support MOA determinations.
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- Mutagenesis, 2016, v. 31, n. 3, p. 255, doi. 10.1093/mutage/gev085
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Genetic toxicology at the crossroads-from qualitative hazard evaluation to quantitative risk assessment.
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- Mutagenesis, 2016, v. 31, n. 3, p. 233, doi. 10.1093/mutage/gew011
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Genotoxicity of flubendazole and its metabolites in vitro and the impact of a new formulation on in vivo aneugenicity.
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- Mutagenesis, 2016, v. 31, n. 3, p. 309, doi. 10.1093/mutage/gev070
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Estimating the carcinogenic potency of chemicals from the in vivo micronucleus test.
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- Mutagenesis, 2016, v. 31, n. 3, p. 347, doi. 10.1093/mutage/gev043
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Pharmacology-based toxicity assessment: towards quantitative risk prediction in humans.
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- Mutagenesis, 2016, v. 31, n. 3, p. 359, doi. 10.1093/mutage/gev081
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- Article
Dose--Response for Multiple Biomarkers of Exposure and Genotoxic Effect Following Repeated Treatment of Rats with the Alkylating Agents, MMS and MNU.
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- Mutagenesis, 2016, v. 31, n. 3, p. 297, doi. 10.1093/mutage/gev035
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- Article
Quantitative analysis of the relative mutagenicity of five chemical constituents of tobacco smoke in the mouse lymphoma assay.
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- Mutagenesis, 2016, v. 31, n. 3, p. 287, doi. 10.1093/mutage/gev039
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Qualitative and quantitative approaches in the dose--response assessment of genotoxic carcinogens.
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- Mutagenesis, 2016, v. 31, n. 3, p. 341, doi. 10.1093/mutage/gev049
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Approaches for characterizing threshold dose-response relationships for DNA-damage pathways involved in carcinogenicity in vivo and micronuclei formation in vitro.
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- Mutagenesis, 2016, v. 31, n. 3, p. 333, doi. 10.1093/mutage/gev078
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The use of dose-response data in a margin of exposure approach to carcinogenic risk assessment for genotoxic chemicals in food.
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- Mutagenesis, 2016, v. 31, n. 3, p. 329, doi. 10.1093/mutage/gev064
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- Article
Comparison of in vitro and in vivo clastogenic potency based on benchmark dose analysis of flow cytometric micronucleus data.
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- Mutagenesis, 2016, v. 31, n. 3, p. 277, doi. 10.1093/mutage/gev041
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- Article
MutAIT: an online genetic toxicology data portal and analysis tools.
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- Mutagenesis, 2016, v. 31, n. 3, p. 323, doi. 10.1093/mutage/gev050
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- Article