EBSCO Logo
Connecting you to content on EBSCOhost
Results
Title

The phytochemistry and biological diversity of Ferulago genus (Apiaceae): a systematic review.

Authors

Wan Salleh, Wan Mohd Nuzul Hakimi; Abed, Salam Ahmed; Taher, Muhammad; Kassim, Hakimi; Tawang, Alene

Abstract

Objectives The genus Ferulago belonging to the family Apiaceae is a flora widely distributed in Central Asia and the Mediterranean and used in folk medicine. It is administered as a sedative, tonic, digestive, aphrodisiac, also as a treatment for intestinal worms and haemorrhoids. Herein, we reported a review on phytochemistry and its biological activities reported from 1990 up to early 2020. All the information and reported studies concerning Ferulago plants were summarized from the library and digital databases (e.g. Scopus, Medline, Scielo, ScienceDirect, SciFinder and Google Scholar). Key findings The phytochemical investigations of Ferulago species revealed the presence of coumarins as the main bioactive compounds, including daucane derivatives, sesquiterpenes aryl esters, phenol derivatives, flavonoids and essential oils. Moreover, the therapeutic potentials of the pure compounds isolated from the genus Ferulago possess promising properties namely anticholinesterase, antimicrobial, anticoagulant, antileishmanial, antioxidant, antibacterial and antiproliferative. Summary Today, significant advances in phytochemical and biological activity studies of different Ferulago species have been revealed. The traditional uses and reported biological results could be correlated via the chemical characterization of these plants. All these data will support the biologists in the elucidation of the biological mechanisms of these plants.

Subjects

CENTRAL Asia; BIODIVERSITY; BOTANICAL chemistry; GOOGLE Scholar (Web resource); UMBELLIFERAE; ARYL esters; PHYTOCHEMICALS; ESSENTIAL oils

Publication

Journal of Pharmacy & Pharmacology, 2021, Vol 73, Issue 1, p1

ISSN

0022-3573

Publication type

Academic Journal

DOI

10.1093/jpp/rgaa034

EBSCO Connect | Privacy policy | Terms of use | Copyright | Manage my cookies
Journals | Subjects | Sitemap
© 2025 EBSCO Industries, Inc. All rights reserved