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Title

Gene Signatures Revisited.

Authors

Baker, Stuart G.

Abstract

The article revisits a gene signature used to classify cancer specimens. It discusses the application of the three-gene model of Haibe-Kains et al. in the classification. It explores theories of cancer biology to explain the use of a gene signature with only few genes. In addition, the article hopes to use gene signatures to improve treatment decisions.

Subjects

CANCER; GENES; THERAPEUTICS; CLINICAL medicine; BIOLOGY

Publication

JNCI: Journal of the National Cancer Institute, 2012, Vol 104, Issue 4, p262

ISSN

0027-8874

Publication type

Academic Journal

DOI

10.1093/jnci/djr557

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