Works matching AU Kuusisto, Johanna

Results: 117
    1

    Mitochondrial genome copy number measured by DNA sequencing in human blood is strongly associated with metabolic traits via cell-type composition differences.

    Published in:
    Human Genomics, 2021, v. 15, n. 1, p. 1, doi. 10.1186/s40246-021-00335-2
    By:
    • Ganel, Liron;
    • Chen, Lei;
    • Christ, Ryan;
    • Vangipurapu, Jagadish;
    • Young, Erica;
    • Das, Indraniel;
    • Kanchi, Krishna;
    • Larson, David;
    • Regier, Allison;
    • Abel, Haley;
    • Kang, Chul Joo;
    • Scott, Alexandra;
    • Havulinna, Aki;
    • Chiang, Charleston W. K.;
    • Service, Susan;
    • Freimer, Nelson;
    • Palotie, Aarno;
    • Ripatti, Samuli;
    • Kuusisto, Johanna;
    • Boehnke, Michael
    Publication type:
    Article
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    Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study.

    Published in:
    Scientific Reports, 2017, p. 46337, doi. 10.1038/srep46337
    By:
    • de Mello, Vanessa D.;
    • Paananen, Jussi;
    • Lindström, Jaana;
    • Lankinen, Maria A.;
    • Shi, Lin;
    • Kuusisto, Johanna;
    • Pihlajamäki, Jussi;
    • Auriola, Seppo;
    • Lehtonen, Marko;
    • Rolandsson, Olov;
    • Bergdahl, Ingvar A.;
    • Nordin, Elise;
    • Ilanne-Parikka, Pirjo;
    • Keinänen-Kiukaanniemi, Sirkka;
    • Landberg, Rikard;
    • Eriksson, Johan G.;
    • Tuomilehto, Jaakko;
    • Hanhineva, Kati;
    • Uusitupa, Matti
    Publication type:
    Article
    5

    Colocalization of GWAS and eQTL signals at loci with multiple signals identifies additional candidate genes for body fat distribution.

    Published in:
    Human Molecular Genetics, 2019, v. 28, n. 24, p. 4161, doi. 10.1093/hmg/ddz263
    By:
    • Wu, Ying;
    • Broadaway, K Alaine;
    • Raulerson, Chelsea K;
    • Scott, Laura J;
    • Pan, Calvin;
    • Ko, Arthur;
    • He, Aiqing;
    • Tilford, Charles;
    • Fuchsberger, Christian;
    • Locke, Adam E;
    • Stringham, Heather M;
    • Jackson, Anne U;
    • Narisu, Narisu;
    • Kuusisto, Johanna;
    • Pajukanta, Päivi;
    • Collins, Francis S;
    • Boehnke, Michael;
    • Laakso, Markku;
    • Lusis, Aldons J;
    • Civelek, Mete
    Publication type:
    Article
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    Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.

    Published in:
    2008
    By:
    • Wei-Min Chen;
    • Erdos, Michael R.;
    • Jackson, Anne U.;
    • Saxena, Richa;
    • Sanna, Serena;
    • Silver, Kristi D.;
    • Timpson, Nicholas J.;
    • Hansen, Torben;
    • Orrù, Marco;
    • Piras, Maria Grazia;
    • Bonnycastle, Lori L.;
    • Willer, Cristen J.;
    • Lyssenko, Valeriya;
    • Haiqing Shen;
    • Kuusisto, Johanna;
    • Ebrahim, Shah;
    • Sestu, Natascia;
    • Duren, William L.;
    • Spada, Maria Cristina;
    • Stringham, Heather M.
    Publication type:
    journal article
    9

    Decreased plasma C‐reactive protein levels in APOE ε4 allele carriers.

    Published in:
    Annals of Clinical & Translational Neurology, 2018, v. 5, n. 10, p. 1229, doi. 10.1002/acn3.639
    By:
    • Martiskainen, Henna;
    • Stančáková, Alena;
    • Kuusisto, Johanna;
    • Laakso, Markku;
    • Takalo, Mari;
    • Marttinen, Mikael;
    • Natunen, Teemu;
    • Hiltunen, Mikko;
    • Solomon, Alina;
    • Kivipelto, Miia;
    • Herukka, Sanna‐Kaisa;
    • Soininen, Hilkka;
    • Haapasalo, Annakaisa
    Publication type:
    Article
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    Adipose Co-expression networks across Finns and Mexicans identify novel triglyceride-associated genes.

    Published in:
    BMC Medical Genomics, 2012, v. 5, n. 1, p. 61, doi. 10.1186/1755-8794-5-61
    By:
    • Haas, Blake E.;
    • Horvath, Steve;
    • Pietil„inen, Kirsi H.;
    • Cantor, Rita M.;
    • Nikkola, Elina;
    • Weissglas-Volkov, Daphna;
    • Rissanen, Aila;
    • Civelek, Mete;
    • Cruz-Bautista, Ivette;
    • Riba, Laura;
    • Kuusisto, Johanna;
    • Kaprio, Jaakko;
    • Tusie-Luna, Teresa;
    • Laakso, Markku;
    • Aguilar-Salinas, Carlos A.;
    • Pajukanta, P„ivi
    Publication type:
    Article
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    Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations.

    Published in:
    American Journal of Epidemiology, 2009, v. 170, n. 5, p. 537, doi. 10.1093/aje/kwp145
    By:
    • Salanti, Georgia;
    • Southam, Lorraine;
    • Altshuler, David;
    • Ardlie, Kristin;
    • Barroso, Inês;
    • Boehnke, Michael;
    • Cornelis, Marilyn C.;
    • Frayling, Timothy M.;
    • Grallert, Harald;
    • Grarup, Niels;
    • Groop, Leif;
    • Hansen, Torben;
    • Hattersley, Andrew T.;
    • Hu, Frank B.;
    • Hveem, Kristian;
    • Illig, Thomas;
    • Kuusisto, Johanna;
    • Laakso, Markku;
    • Langenberg, Claudia;
    • Lyssenko, Valeriya
    Publication type:
    Article
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    Effects of age, amyloid, sex, and APOE ε4 on the CSF proteome in normal cognition.

    Published in:
    Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2022, v. 14, n. 1, p. 1, doi. 10.1002/dad2.12286
    By:
    • Wesenhagen, Kirsten E.J.;
    • Gobom, Johan;
    • Bos, Isabelle;
    • Vos, Stephanie J.B.;
    • Martinez‐Lage, Pablo;
    • Popp, Julius;
    • Tsolaki, Magda;
    • Vandenberghe, Rik;
    • Freund‐Levi, Yvonne;
    • Verhey, Frans;
    • Lovestone, Simon;
    • Streffer, Johannes;
    • Dobricic, Valerija;
    • Bertram, Lars;
    • Blennow, Kaj;
    • Pikkarainen, Maria;
    • Hallikainen, Merja;
    • Kuusisto, Johanna;
    • Laakso, Markku;
    • Soininen, Hilkka
    Publication type:
    Article
    23

    Lamin A/C mutation affecting primarily the right side of the heart.

    Published in:
    Cardiogenetics, 2013, v. 3, n. 1, p. 1, doi. 10.4081/cardiogenetics.2013.e1
    By:
    • Ollila, Laura;
    • Kuusisto, Johanna;
    • Peuhkurinen, Keijo;
    • Kärkkäinen, Satu;
    • Tuomainen, Petri;
    • Kaartinen, Maija;
    • Raheem, Olayinka;
    • Udd, Bjarne;
    • Magga, Jarkko;
    • Rapola, Janne;
    • Lahtinen, Annukka M.;
    • Lehtonen, Eero;
    • Holmström, Miia;
    • Kivistö, Sari;
    • Widén, Elisabeth;
    • Saksa, Markku;
    • Heliö, Tiina
    Publication type:
    Article
    24

    Predicting glycated hemoglobin levels in the non-diabetic general population: Development and validation of the DIRECT-DETECT prediction model - a DIRECT study.

    Published in:
    PLoS ONE, 2017, v. 12, n. 2, p. 1, doi. 10.1371/journal.pone.0171816
    By:
    • Rauh, Simone P.;
    • Heymans, Martijn W.;
    • Koopman, Anitra D. M.;
    • Nijpels, Giel;
    • Stehouwer, Coen D.;
    • Thorand, Barbara;
    • Rathmann, Wolfgang;
    • Meisinger, Christa;
    • Peters, Annette;
    • de las Heras Gala, Tonia;
    • Glümer, Charlotte;
    • Pedersen, Oluf;
    • Cederberg, Henna;
    • Kuusisto, Johanna;
    • Laakso, Markku;
    • Pearson, Ewan R.;
    • Franks, Paul W.;
    • Rutters, Femke;
    • Dekker, Jacqueline M.
    Publication type:
    Article
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    Ketone body production is differentially altered in steatosis and non-alcoholic steatohepatitis in obese humans.

    Published in:
    Liver International, 2015, v. 35, n. 7, p. 1853, doi. 10.1111/liv.12769
    By:
    • Männistö, Ville T.;
    • Simonen, Marko;
    • Hyysalo, Jenni;
    • Soininen, Pasi;
    • Kangas, Antti J.;
    • Kaminska, Dorota;
    • Matte, Ananda K.;
    • Venesmaa, Sari;
    • Käkelä, Pirjo;
    • Kärjä, Vesa;
    • Arola, Johanna;
    • Gylling, Helena;
    • Cederberg, Henna;
    • Kuusisto, Johanna;
    • Laakso, Markku;
    • Yki ‐ Järvinen, Hannele;
    • Ala ‐ Korpela, Mika;
    • Pihlajamäki, Jussi
    Publication type:
    Article
    29

    Systems Genetics Approach to Biomarker Discovery: GPNMB and Heart Failure in Mice and Humans.

    Published in:
    G3: Genes | Genomes | Genetics, 2018, v. 8, n. 11, p. 3499, doi. 10.1534/g3.118.200655
    By:
    • Liang-Yu Lin;
    • Sunny Chun Chang;
    • O'Hearn, Jim;
    • Hui, Simon T.;
    • Seldin, Marcus;
    • Gupta, Pritha;
    • Bondar, Galyna;
    • Deng, Mario;
    • Jauhiainen, Raimo;
    • Kuusisto, Johanna;
    • Laakso, Markku;
    • Sinsheimer, Janet S.;
    • Deb, Arjun;
    • Rau, Christoph;
    • Shuxun Ren;
    • Yibin Wang;
    • Lusis, Aldons J.;
    • Wang, Jessica J.;
    • Huertas-Vazquez, Adriana
    Publication type:
    Article
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    Human iPSC-derived pericyte-like cells carrying APP Swedish mutation overproduce beta-amyloid and induce cerebral amyloid angiopathy-like changes.

    Published in:
    Fluids & Barriers of the CNS, 2024, v. 21, n. 1, p. 1, doi. 10.1186/s12987-024-00576-y
    By:
    • Wu, Ying-Chieh;
    • Lehtonen, Šárka;
    • Trontti, Kalevi;
    • Kauppinen, Riitta;
    • Kettunen, Pinja;
    • Leinonen, Ville;
    • Laakso, Markku;
    • Kuusisto, Johanna;
    • Hiltunen, Mikko;
    • Hovatta, Iiris;
    • Freude, Kristine;
    • Dhungana, Hiramani;
    • Koistinaho, Jari;
    • Rolova, Taisia
    Publication type:
    Article
    32
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    Common variant in MTNR1B associated with increased risk of type 2 diabetes and impaired early insulin secretion.

    Published in:
    Nature Genetics, 2009, v. 41, n. 1, p. 82, doi. 10.1038/ng.288
    By:
    • Lyssenko, Valeriya;
    • Nagorny, Cecilia L. F.;
    • Erdos, Michael R.;
    • Wierup, Nils;
    • Jonsson, Anna;
    • Spégel, Peter;
    • Bugliani, Marco;
    • Saxena, Richa;
    • Fex, Malin;
    • Pulizzi, Nicolo;
    • Isomaa, Bo;
    • Tuomi, Tiinamaija;
    • Nilsson, Peter;
    • Kuusisto, Johanna;
    • Tuomilehto, Jaakko;
    • Boehnke, Michael;
    • Altshuler, David;
    • Sundler, Frank;
    • Eriksson, Johan G.;
    • Jackson, Anne U.
    Publication type:
    Article
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    The influence of insulin resistance on cerebrospinal fluid and plasma biomarkers of Alzheimer's pathology.

    Published in:
    Alzheimer's Research & Therapy, 2017, v. 9, p. 1, doi. 10.1186/s13195-017-0258-6
    By:
    • Westwood, Sarah;
    • Liu, Benjamine;
    • Baird, Alison L.;
    • Anand, Sneha;
    • Nevado-Holgado, Alejo J.;
    • Newby, Danielle;
    • Pikkarainen, Maria;
    • Hallikainen, Merja;
    • Kuusisto, Johanna;
    • Streffer, Johannes R.;
    • Novak, Gerald;
    • Blennow, Kaj;
    • Andreasson, Ulf;
    • Zetterberg, Henrik;
    • Smith, Ulf;
    • Laakso, Markku;
    • Soininen, Hilkka;
    • Lovestone, Simon
    Publication type:
    Article
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    Adiponectin GWAS loci harboring extensive allelic heterogeneity exhibit distinct molecular consequences.

    Published in:
    PLoS Genetics, 2020, v. 16, n. 9, p. 1, doi. 10.1371/journal.pgen.1009019
    By:
    • Spracklen, Cassandra N.;
    • Iyengar, Apoorva K.;
    • Vadlamudi, Swarooparani;
    • Raulerson, Chelsea K.;
    • Jackson, Anne U.;
    • Brotman, Sarah M.;
    • Wu, Ying;
    • Cannon, Maren E.;
    • Davis, James P.;
    • Crain, Aaron T.;
    • Currin, Kevin W.;
    • Perrin, Hannah J.;
    • Narisu, Narisu;
    • Stringham, Heather M.;
    • Fuchsberger, Christian;
    • Locke, Adam E.;
    • Welch, Ryan P.;
    • Kuusisto, Johanna K.;
    • Pajukanta, Päivi;
    • Scott, Laura J.
    Publication type:
    Article
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    Association Analysis of Peroxisome Proliferator-Activated Receptor Gamma Polymorphisms and Late Onset Alzheimer’s Disease in the Finnish Population.

    Published in:
    Dementia & Geriatric Cognitive Disorders, 2006, v. 22, n. 5/6, p. 449, doi. 10.1159/000095857
    By:
    • Koivisto, Anne M.;
    • Helisalmi, Seppo;
    • Pihlajamäki, Jussi;
    • Hiltunen, Mikko;
    • Koivisto, Keijo;
    • Moilanen, Leena;
    • Kuusisto, Johanna;
    • Helkala, Eeva-Liisa;
    • Hänninen, Tuomo;
    • Kervinen, Kari;
    • Kesäniemi, Y. Antero;
    • Laakso, Markku;
    • Soininen, Hilkka
    Publication type:
    Article
    48

    Epigenome-wide association in adipose tissue from the METSIM cohort.

    Published in:
    Human Molecular Genetics, 2018, v. 27, n. 10, p. 1830, doi. 10.1093/hmg/ddy093
    By:
    • Orozco, Luz D.;
    • Farrell, Colin;
    • Hale, Christopher;
    • Rubbi, Liudmilla;
    • Rinaldi, Arturo;
    • Civelek, Mete;
    • Pan, Calvin;
    • Lam, Larry;
    • Montoya, Dennis;
    • Edillor, Chantle;
    • Seldin, Marcus;
    • Boehnke, Michael;
    • Mohlke, Karen L.;
    • Jacobsen, Steve;
    • Kuusisto, Johanna;
    • Laakso, Markku;
    • Lusis, Aldons J.;
    • Pellegrini, Matteo
    Publication type:
    Article
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