Works matching Mutation and mutagenesis
Results: 1733
A machine learning enhanced EMS mutagenesis probability map for efficient identification of causal mutations in Caenorhabditis elegans.
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- PLoS Genetics, 2024, v. 20, n. 8, p. 1, doi. 10.1371/journal.pgen.1011377
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- Publication type:
- Article
High-throughput mutagenesis identifies mutations and RNA-binding proteins controlling CD19 splicing and CART-19 therapy resistance.
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- Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31818-y
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- Publication type:
- Article
Mutation Induced Extinction in Finite Populations: Lethal Mutagenesis and Lethal Isolation.
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- PLoS Computational Biology, 2012, v. 8, n. 8, p. 1, doi. 10.1371/journal.pcbi.1002609
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- Publication type:
- Article
Quantitative evaluation of DNA damage and mutation rate by atmospheric and room-temperature plasma (ARTP) and conventional mutagenesis.
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- Applied Microbiology & Biotechnology, 2015, v. 99, n. 13, p. 5639, doi. 10.1007/s00253-015-6678-y
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- Article
Hypomorphic mutation in the large subunit of replication protein A affects mutagenesis by human APOBEC cytidine deaminases in yeast.
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- G3: Genes | Genomes | Genetics, 2024, v. 14, n. 10, p. 1, doi. 10.1093/g3journal/jkae196
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- Publication type:
- Article
Prenatal diagnosis of X-linked hyper-IGM syndrome by direct detection of mutation Q220X in the CD40L gene using PCR-mediated site directed mutagenesis.
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- Prenatal Diagnosis, 2000, v. 20, n. 10, p. 822, doi. 10.1002/1097-0223(200010)20:10<822::AID-PD935>3.0.CO;2-K
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- Article
Prediction of the Effects of Missense Mutations on Human Myeloperoxidase Protein Stability Using In Silico Saturation Mutagenesis.
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- Genes, 2022, v. 13, n. 8, p. 1412, doi. 10.3390/genes13081412
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- Article
Computational Saturation Mutagenesis to Investigate the Effects of Neurexin-1 Mutations on AlphaFold Structure.
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- Genes, 2022, v. 13, n. 5, p. 789, doi. 10.3390/genes13050789
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- Article
A new mouse model of type 2 diabetes, produced by N-ethyl-nitrosourea mutagenesis, is the result of a missense mutation in the glucokinase gene.
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- 2004
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- Publication type:
- journal article
Mechanisms of mutagenesis induced by DNA lesions: multiple factors affect mutations in translesion DNA synthesis.
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- 2020
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- Publication type:
- Literature Review
Identification of dominant mutations that confer increased aluminium tolerance through mutagenesis of the Al-sensitive Arabidopsis mutant, als3-1.
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- Journal of Experimental Botany, 2006, v. 57, n. 4, p. 943, doi. 10.1093/jxb/erj080
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- Publication type:
- Article
Computational saturation mutagenesis to explore the effect of pathogenic mutations on extra-cellular domains of TREM2 associated with Alzheimer's and Nasu-Hakola disease.
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- Journal of Molecular Modeling, 2023, v. 29, n. 11, p. 1, doi. 10.1007/s00894-023-05770-7
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- Publication type:
- Article
Identification of a Novel Point Mutation of Mouse Proto-Oncogene c-kit Through N-Ethyl-N-nitrosourea Mutagenesis.
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- Genetics, 2005, v. 169, n. 2, p. 819, doi. 10.1534/genetics.104.027177
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- Publication type:
- Article
Dependence of Epistasis on Environment and Mutation Severity as Revealed by in Silico Mutagenesis of Phage T7.
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- Genetics, 2002, v. 160, n. 4, p. 1273, doi. 10.1093/genetics/160.4.1273
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- Publication type:
- Article
An updated system for the targeted mutagenesis of the psbDI:psbC operon in Synechocystis sp. PCC 6803: mutations targeting Asp460 in CP43 of Photosystem II reduce oxygen-evolving activity and perturb electron transfer in the quinone-Fe-acceptor complex.
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- New Zealand Journal of Botany, 2020, v. 58, n. 4, p. 389, doi. 10.1080/0028825X.2020.1771383
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- Article
An improved system for the targeted mutagenesis of the psbA2 gene in Synechocystis sp. PCC 6803: mutation of D1-Glu244 to His impairs electron transfer between Q<sub>A</sub> and Q<sub>B</sub> of Photosystem II.
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- New Zealand Journal of Botany, 2019, v. 57, n. 2, p. 125, doi. 10.1080/0028825X.2019.1617321
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- Publication type:
- Article
Zinc finger nucleases for targeted mutagenesis and repair of the sickle-cell disease mutation: An in-silico study.
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- BMC Blood Disorders, 2012, v. 12, n. 1, p. 5, doi. 10.1186/1471-2326-12-5
- Publication type:
- Article
Adaptive Resistance Mutations at Suprainhibitory Concentrations Independent of SOS Mutagenesis.
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- Molecular Biology & Evolution, 2021, v. 38, n. 10, p. 4095, doi. 10.1093/molbev/msab196
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- Publication type:
- Article
Amino acid substitutions in random mutagenesis libraries: lessons from analyzing 3000 mutations.
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- Applied Microbiology & Biotechnology, 2017, v. 101, n. 8, p. 3177, doi. 10.1007/s00253-016-8035-1
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- Publication type:
- Article
Population persistence under high mutation rate: From evolutionary rescue to lethal mutagenesis.
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- Evolution, 2019, v. 73, n. 8, p. 1517, doi. 10.1111/evo.13771
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- Publication type:
- Article
A shifting mutational landscape in 6 nutritional states: Stress-induced mutagenesis as a series of distinct stress input–mutation output relationships.
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- PLoS Biology, 2017, v. 15, n. 6, p. 1, doi. 10.1371/journal.pbio.2001477
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- Publication type:
- Article
Whole exome sequencing reveals a functional mutation in the GAIN domain of the Bai2 receptor underlying a forward mutagenesis hyperactivity QTL.
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- Mammalian Genome, 2017, v. 28, n. 11/12, p. 465, doi. 10.1007/s00335-017-9716-5
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- Publication type:
- Article
A phenotype-driven ENU mutagenesis screen for the identification of dominant mutations involved in alcohol consumption.
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- Mammalian Genome, 2008, v. 19, n. 2, p. 77, doi. 10.1007/s00335-007-9087-4
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- Article
Identification of mutations from phenotype-driven ENU mutagenesis in mouse Chromosome 7.
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- Mammalian Genome, 2005, v. 16, n. 8, p. 555, doi. 10.1007/s00335-005-0032-0
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- Publication type:
- Article
Genomewide two-generation screens for recessive mutations by ES cell mutagenesis.
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- Mammalian Genome, 2004, v. 15, n. 12, p. 960, doi. 10.1007/s00335-004-2406-0
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- Publication type:
- Article
Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-87226-7
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- Article
Generation of eight adjacent mutations in a single step using a site-directed mutagenesis kit.
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- Clinical Chemistry & Laboratory Medicine, 2004, v. 42, n. 4, p. 384, doi. 10.1515/CCLM.2004.068
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- Publication type:
- Article
TP53 mutations in squamous-cell carcinomas of the conjunctiva: evidence for UV-induced mutagenesis.
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- Mutagenesis, 2004, v. 19, n. 5, p. 399, doi. 10.1093/mutage/geh048
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- Article
Editorial: Mutational breeding: from induced mutations to site-directed mutagenesis.
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- Frontiers in Plant Science, 2024, p. 1, doi. 10.3389/fpls.2024.1511363
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- Publication type:
- Article
Rapid Mutation of <i>Spirulina platensis</i> by a New Mutagenesis System of Atmospheric and Room Temperature Plasmas (ARTP) and Generation of a Mutant Library with Diverse Phenotypes.
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- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077046
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- Publication type:
- Article
Random Mutagenesis of β-Tubulin Defines a Set of Dispersed Mutations That Confer Paclitaxel Resistance.
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- Pharmaceutical Research, 2012, v. 29, n. 11, p. 2994, doi. 10.1007/s11095-012-0794-5
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- Publication type:
- Article
Enhancement of the Enzymatic Activity of Escherichia coli Acetyl Esterase by a Double Mutation Obtained by Random Mutagenesis.
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- Bioscience, Biotechnology & Biochemistry, 2012, v. 76, n. 11, p. 2082, doi. 10.1271/bbb.120430
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- Publication type:
- Article
An N-ethyl-N-Nitrosourea Mutagenesis Screen in Mice Reveals a Mutation in Nuclear Respiratory Factor 1 (Nrf1) Altering the DNA Methylation State and Correct Embryonic Development.
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- Animals (2076-2615), 2021, v. 11, n. 7, p. 2103, doi. 10.3390/ani11072103
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- Publication type:
- Article
Germline mutagenesis, automated meiotic mapping, and the discovery of mutations that suppress disease.
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- Italian Journal of Anatomy & Embryology / Archivio Italiano di Anatomia Ed Embriologia, 2021, v. 125, p. 1
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- Publication type:
- Article
ENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response.
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- BMC Research Notes, 2013, v. 6, n. 1, p. 1, doi. 10.1186/1756-0500-6-203
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- Publication type:
- Article
Polymerase chain reaction (PCR) mutagenesis enabling rapid non-radioactive detection of common β-thalassaemia mutations in Mediterraneans.
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- British Journal of Haematology, 1991, v. 78, n. 1, p. 100, doi. 10.1111/j.1365-2141.1991.tb04389.x
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- Article
Mutagenesis analysis of T380R mutation in the envelope protein of yellow fever virus.
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- Virology Journal, 2014, v. 11, n. 1, p. 1, doi. 10.1186/1743-422X-11-60
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- Publication type:
- Article
Site-directed saturation mutagenesis at residue F420 and recombination with another beneficial mutation of Ralstonia eutropha polyhydroxyalkanoate synthase.
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- Biotechnology Letters, 2005, v. 27, n. 10, p. 705, doi. 10.1007/s10529-005-5186-z
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- Publication type:
- Article
Induction of new mutations in a mouse t-haplotype using ethylnitrosourea mutagenesis.
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- Genetics Research, 1986, v. 47, n. 3, p. 187, doi. 10.1017/S0016672300023119
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- Publication type:
- Article
A hypothesis for what conformation of the major adduct of (+)-anti-B[α]PDE (N2-dG) causes G→T versus G→A mutations based upon a correlation between mutagenesis and molecular modeling results.
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- Carcinogenesis, 1999, v. 20, n. 1, p. 95, doi. 10.1093/carcin/20.1.95
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- Publication type:
- Article
Specificity of mutagenesis by 4-aminobiphenyl: mutations at G residues in bacteriophage M13 DNA and G-->C transversions at a unique dG(8-ABP) lesion in single-stranded DNA.
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- Carcinogenesis, 1997, v. 18, n. 12, p. 2403, doi. 10.1093/carcin/18.12.2403
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- Publication type:
- Article
7-Methoxy-2-nitronaphtho(2, l-b)furan (R7000)-induced mutation spectrum in the lacI gene of Escherichia coli: influence of SOS mutagenesis.
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- Carcinogenesis, 1996, v. 17, n. 12, p. 2543, doi. 10.1093/carcin/17.12.2543
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- Publication type:
- Article
The role of adduct site-specific mutagenesis in understanding how carcinogen-DNA adducts cause mutations: perspective, prospects and problems.
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- Carcinogenesis, 1996, v. 17, n. 5, p. 895, doi. 10.1093/carcin/17.5.895
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- Publication type:
- Article
A random mutagenesis screen enriched for missense mutations in bacterial effector proteins.
- Published in:
- G3: Genes | Genomes | Genetics, 2024, v. 14, n. 9, p. 1, doi. 10.1093/g3journal/jkae158
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- Publication type:
- Article
Fast neutron mutagenesis in soybean enriches for small indels and creates frameshift mutations.
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- G3: Genes | Genomes | Genetics, 2022, v. 12, n. 2, p. 1, doi. 10.1093/g3journal/jkab431
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- Publication type:
- Article
Are transversion mutations better? A Mutagenesis Assistant Program analysis on P450 BM-3 heme domain.
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- Biotechnology Journal, 2007, v. 2, n. 1, p. 133, doi. 10.1002/biot.200600201
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- Article
Site-directed mutagenesis of the T4 endonuclease V Gene: Mutations which enhance enzyme specific activity at low salt concentrations.
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- Proteins, 1989, v. 6, n. 2, p. 128, doi. 10.1002/prot.340060204
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- Publication type:
- Article
Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.
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- 2015
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- Publication type:
- journal article
Positive Signature-Tagged Mutagenesis in Pseudomonas aeruginosa: Tracking Patho-Adaptive Mutations Promoting Airways Chronic Infection.
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- PLoS Pathogens, 2011, v. 7, n. 2, p. 1, doi. 10.1371/journal.ppat.1001270
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- Publication type:
- Article
Type X Collagen NC1 Mutations Produced by Site-directed Mutagenesis Prevent In Vitro Assemblya.
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- Annals of the New York Academy of Sciences, 1996, v. 785, n. 1, p. 231, doi. 10.1111/j.1749-6632.1996.tb56269.x
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- Publication type:
- Article