Loop diuretics in cardiovascular disease: friend or foe?

Rosengren, Annika

This article discusses the use of loop diuretics in the treatment of cardiovascular disease, specifically heart failure. Loop diuretics are commonly used to relieve symptoms of congestion in heart failure patients, but their impact on prognosis is unclear. The article highlights a study that examined the association between loop diuretic use and outcomes in patients with various vascular disorders. The study found that patients treated with loop diuretics had higher mortality rates, even if they did not have a recorded diagnosis of heart failure. However, the study's observational nature prevents the establishment of causality. The article suggests that further research, such as randomized trials, is needed to determine the necessity and potential risks of loop diuretic use in cardiovascular disease treatment.

HEART failure; CONGESTIVE heart failure; SYMPATHETIC nervous system; HEART failure patients; PERIPHERAL vascular diseases; ANGIOTENSIN-receptor blockers

European Heart Journal, 2024, Vol 45, Issue 37, p3850

0195-668X

Academic Journal

10.1093/eurheartj/ehae483