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Title: Endothelin signalling regulates volume-sensitive Cl− current via NADPH oxidase and mitochondrial reactive oxygen species.
Authors: Wu Deng; Baki, Lia; Baumgarten, Clive M.
Abstract: Aims: We assessed regulation of volume-sensitive Cl− current (ICl,swell) by endothelin-1 (ET-1) and characterized the signalling pathway responsible for its activation in rabbit atrial and ventricular myocytes.
Subjects: ENDOTHELINS; REACTIVE oxygen species; LABORATORY rabbits; MOLECULES; ENDOTHELIUM; HEART failure
Publication: Cardiovascular Research, 2010, Vol 88, Issue 1, p93
ISSN: 0008-6363
Publication type: Academic Journal
DOI: 10.1093/cvr/cvq125

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Endothelin signalling regulates volume-sensitive Cl− current via NADPH oxidase and mitochondrial reactive oxygen species.