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Title

Endothelin signalling regulates volume-sensitive Cl− current via NADPH oxidase and mitochondrial reactive oxygen species.

Authors

Wu Deng; Baki, Lia; Baumgarten, Clive M.

Abstract

Aims: We assessed regulation of volume-sensitive Cl− current (ICl,swell) by endothelin-1 (ET-1) and characterized the signalling pathway responsible for its activation in rabbit atrial and ventricular myocytes.

Subjects

ENDOTHELINS; REACTIVE oxygen species; LABORATORY rabbits; MOLECULES; ENDOTHELIUM; HEART failure

Publication

Cardiovascular Research, 2010, Vol 88, Issue 1, p93

ISSN

0008-6363

Publication type

Academic Journal

DOI

10.1093/cvr/cvq125

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