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The safety, tolerability, and pharmacokinetic profile of GSK2838232, a novel 2nd generation HIV maturation inhibitor, as assessed in healthy subjects.
Published in:
Pharmacology Research & Perspectives, 2018, v. 6, n. 4, p. 1, doi. 10.1002/prp2.408
By:
- Johnson, Mark;
- Jewell, Roxanne C.;
- Peppercorn, Amanda;
- Gould, Elizabeth;
- Jianfeng Xu;
- Yu Lou;
- Davies, Matthew;
- Baldwin, Sandra;
- Tenorio, Allan R.;
- Burke, Matthew;
- Jeffrey, Jerry;
- Johns, Brian A.
Publication type:
Article
A Phase 1 Study to Assess the Relative Bioavailability, Food Effect, and Safety of a Tablet Formulation of GSK2838232, a Novel HIV Maturation Inhibitor in Healthy Participants After Single and Repeated Doses.
Published in:
Clinical Pharmacology in Drug Development, 2020, v. 9, n. 8, p. 972, doi. 10.1002/cpdd.820
By:
- Johnson, Mark;
- Jewell, Roxanne C.;
- Gan, Jianjun;
- Dumont, Etienne;
- Burns, Olivia;
- Johns, Brian A.
Publication type:
Article
Food Increases the Bioavailability of Acitretin.
Published in:
1988
By:
- McNamara, Patrick J.;
- Jewell, Roxanne C.;
- Jensen, Bradford K.;
- Brindley, Charles J.
Publication type:
Other
Ofatumumab retreatment and maintenance in fludarabine-refractory chronic lymphocytic leukaemia patients.
Published in:
British Journal of Haematology, 2015, v. 170, n. 1, p. 40, doi. 10.1111/bjh.13380
By:
- Österborg, Anders;
- Wierda, William G.;
- Mayer, Jiří;
- Hess, Georg;
- Hillmen, Peter;
- Schetelig, Johannes;
- Schuh, Anna;
- Smolej, Lukáš;
- Beck, Christian;
- Dreyfus, Brigitte;
- Hellman, Andrzej;
- Kozlowski, Piotr;
- Pfreundschuh, Michael;
- Rizzi, Rita;
- Spacek, Martin;
- Phillips, Jennifer L.;
- Gupta, Ira V.;
- Williams, Vanessa;
- Jewell, Roxanne C.;
- Nebot, Noelia
Publication type:
Article
A multicentre, phase II trial of ofatumumab monotherapy in relapsed/progressive diffuse large B-cell lymphoma.
Published in:
British Journal of Haematology, 2013, v. 163, n. 3, p. 334, doi. 10.1111/bjh.12537
By:
- Coiffier, Bertrand;
- Radford, John;
- Bosly, André;
- Martinelli, Giovanni;
- Barca, Gabriela;
- Davies, Andrew;
- Decaudin, Didier;
- Gallop‐Evans, Eve;
- Padmanabhan‐Iyer, Swaminathan;
- Eygen, Koen;
- Wu, Ka Lung;
- Gupta, Ira V.;
- Lin, Thomas S.;
- Goldstein, Nancy;
- Jewell, Roxanne C.;
- Winter, Paul;
- Lisby, Steen
Publication type:
Article
Ofatumumab, the first human anti-CD20 monoclonal antibody for the treatment of B cell hematologic malignancies.
Published in:
Annals of the New York Academy of Sciences, 2012, v. 1263, n. 1, p. 43, doi. 10.1111/j.1749-6632.2012.06661.x
By:
- Gupta, Ira V.;
- Jewell, Roxanne C.
Publication type:
Article
Effects of Probenecid on the pharmacokinetics and pharmacodynamics of adinazolam in humans.
Published in:
Clinical Pharmacology & Therapeutics, 1994, v. 56, n. 2, p. 133, doi. 10.1038/clpt.1994.116
By:
- Golden, Pamela L;
- Warner, Patricia E;
- Fleishaker, Joseph C;
- Jewell, Roxanne C;
- Millikin, Steven;
- Lyon, James;
- Brouwer, Kim L R
Publication type:
Article
Belantamab mafodotin concentration–QTc relationships in patients with relapsed or refractory multiple myeloma from the DREAMM‐1 and ‐2 studies.
Published in:
British Journal of Clinical Pharmacology, 2024, v. 90, n. 10, p. 2571, doi. 10.1111/bcp.16133
By:
- Jewell, Roxanne C.;
- Mills, Richard J.;
- Farrell, Colm;
- Visser, Sandra A. G.
Publication type:
Article
Phase I Study of Ofatumumab, a Human Anti-CD20 Antibody, in Japanese Patients with Relapsed or Refractory Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma.
Published in:
Japanese Journal of Clinical Oncology, 2013, v. 43, n. 5, p. 466, doi. 10.1093/jjco/hyt022
By:
- Ogura, Michinori;
- Hatake, Kiyohiko;
- Tobinai, Kensei;
- Uchida, Toshiki;
- Suzuki, Tatsuya;
- Terui, Yasuhito;
- Yokoyama, Masahiro;
- Maruyama, Dai;
- Mori, Masakazu;
- Jewell, Roxanne C.;
- Katsura, Koichi;
- Hotta, Tomomitsu
Publication type:
Article
A Phase IIa Study Evaluating Safety, Pharmacokinetics, and Antiviral Activity of GSK2838232, a Novel, Second-generation Maturation Inhibitor, in Participants With Human Immunodeficiency Virus Type 1 Infection.
Published in:
Clinical Infectious Diseases, 2020, v. 71, n. 5, p. 1255, doi. 10.1093/cid/ciz938
By:
- DeJesus, Edwin;
- Harward, Sara;
- Jewell, Roxanne C;
- Johnson, Mark;
- Dumont, Etienne;
- Wilches, Viviana;
- Halliday, Fiona;
- Talarico, Christine L;
- Jeffrey, Jerry;
- Gan, Jianjun;
- Xu, Jianfeng;
- Felizarta, Franco;
- Scribner, Anita;
- Ramgopal, Moti;
- Benson, Paul;
- Johns, Brian A
Publication type:
Article
Exposure–Response Analyses for Therapeutic Dose Selection of Belantamab Mafodotin in Patients With Relapsed/Refractory Multiple Myeloma.
Published in:
Clinical Pharmacology & Therapeutics, 2021, v. 110, n. 5, p. 1282, doi. 10.1002/cpt.2409
By:
- Ferron‐Brady, Geraldine;
- Rathi, Chetan;
- Collins, Jon;
- Struemper, Herbert;
- Opalinska, Joanna;
- Visser, Sandra;
- Jewell, Roxanne C.
Publication type:
Article
Longitudinal efficacy and safety modeling and simulation framework to aid dose selection of belantamab mafodotin for patients with multiple myeloma.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 10, p. 1411, doi. 10.1002/psp4.13016
By:
- Collins, Jon;
- van Noort, Martijn;
- Rathi, Chetan;
- Post, Teun M.;
- Struemper, Herbert;
- Jewell, Roxanne C.;
- Ferron‐Brady, Geraldine
Publication type:
Article
Population pharmacokinetics of belantamab mafodotin, a BCMA‐targeting agent in patients with relapsed/refractory multiple myeloma.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2021, v. 10, n. 8, p. 851, doi. 10.1002/psp4.12660
By:
- Rathi, Chetan;
- Collins, Jon;
- Struemper, Herbert;
- Opalinska, Joanna;
- Jewell, Roxanne C.;
- Ferron‐Brady, Geraldine
Publication type:
Article
Single-agent belantamab mafodotin for relapsed/refractory multiple myeloma: analysis of the lyophilised presentation cohort from the pivotal DREAMM-2 study.
Published in:
Blood Cancer Journal, 2020, v. 10, n. 10, p. 1, doi. 10.1038/s41408-020-00369-0
By:
- Richardson, Paul G.;
- Lee, Hans C.;
- Abdallah, Al-Ola;
- Cohen, Adam D.;
- Kapoor, Prashant;
- Voorhees, Peter M.;
- Hoos, Axel;
- Wang, Karrie;
- Baron, January;
- Piontek, Trisha;
- Byrne, Julie;
- Richmond, Scott;
- Jewell, Roxanne C.;
- Opalinska, Joanna;
- Gupta, Ira;
- Lonial, Sagar
Publication type:
Article
Assessment of the effect of ofatumumab on cardiac repolarization.
Published in:
Journal of Clinical Pharmacology, 2015, v. 55, n. 1, p. 114, doi. 10.1002/jcph.376
By:
- Jewell, Roxanne C.;
- Laubscher, Kevin;
- Lewis, Eric;
- Fang, Lei;
- Gafoor, Zarina;
- Carey, Jodi;
- McKeown, Astrid;
- West, Sarah;
- Wright, Oliver;
- Sedoti, Donna;
- Dixon, Iestyn;
- Hottenstein, Charles Scott;
- Chan, Geoffrey
Publication type:
Article
Population pharmacokinetics of ofatumumab in patients with chronic lymphocytic leukemia, follicular lymphoma, and rheumatoid arthritis.
Published in:
Journal of Clinical Pharmacology, 2014, v. 54, n. 7, p. 818, doi. 10.1002/jcph.268
By:
- Struemper, Herbert;
- Sale, Mark;
- Patel, Bela R.;
- Østergaard, Mikkel;
- Österborg, Anders;
- Wierda, William G.;
- Hagenbeek, Anton;
- Coiffier, Bertrand;
- Jewell, Roxanne C.
Publication type:
Article
A Phase I Study to Characterize the Safety, Tolerability, and Pharmacokinetics of Topotecan at 4 mg/m² Administered Weekly as a 30-Minute Intravenous Infusion in Patients With Cancer.
Published in:
Journal of Clinical Pharmacology, 2010, v. 50, n. 3, p. 268, doi. 10.1177/0091270009343699
By:
- Curtis, Kelly K.;
- Hartney, Jean T.;
- Jewell, Roxanne C.;
- Park, Jung W.;
- Lebowitz, Peter F.;
- Griffin, Pamela P.;
- Borad, Mitesh J.;
- Fitch, Tom R.;
- Northfelt, Donald W.
Publication type:
Article
Chemoimmunotherapy with ofatumumab in combination with CHOP in previously untreated follicular lymphoma.
Published in:
British Journal of Haematology, 2012, v. 157, n. 4, p. 438, doi. 10.1111/j.1365-2141.2012.09086.x
By:
- Czuczman, Myron S.;
- Hess, Georg;
- Gadeberg, Ole V.;
- Pedersen, Lars M.;
- Goldstein, Nancy;
- Gupta, Ira;
- Jewell, Roxanne C.;
- Lin, Thomas S.;
- Lisby, Steen;
- Strange, Claus;
- Windfeld, Kristian;
- Viardot, Andreas
Publication type:
Article
A Phase I Study of Weekly Topotecan in Combination with Pemetrexed in Patients with Advanced Malignancies.
Published in:
Oncologist, 2010, v. 15, n. 9, p. 954, doi. 10.1634/theoncologist.2010-0006
By:
- BURRIS III, HOWARD A.;
- INFANTE, JEFFREY R.;
- JEWELL, ROXANNE C.;
- SPIGEL, DAVID R.;
- GRECO, F. ANTHONY;
- THOMPSON, DANA S.;
- JONES, SUZANNE F.
Publication type:
Article
Safety and efficacy of belantamab mafodotin with pembrolizumab in patients with relapsed or refractory multiple myeloma.
Published in:
Cancer (0008543X), 2024, v. 130, n. 15, p. 2629, doi. 10.1002/cncr.35319
By:
- Suvannasankha, Attaya;
- Bahlis, Nizar;
- Trudel, Suzanne;
- Weisel, Katja;
- Koenecke, Christian;
- Oriol, Albert;
- Voorhees, Peter M.;
- Alonso, Aranzazu A.;
- Callander, Natalie S.;
- Mateos, María‐Victoria;
- Reddy, Nishitha;
- Hakim, Shawn;
- LaMacchia, John;
- Patel, Nashita;
- Williams, Danaé;
- Jewell, Roxanne C.;
- Zhou, Xiangdong;
- Gupta, Ira;
- Opalinska, Joanna;
- Nooka, Ajay K.
Publication type:
Article

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