Works matching DE "CILASTATIN"

Results: 62
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    Pharmacokinetics, Safety, and Tolerability of Imipenem/Cilastatin/Relebactam in Children with Confirmed or Suspected Gram‐Negative Bacterial Infections: A Phase 1b, Open‐Label, Single‐Dose Clinical Trial.

    Published in:
    Journal of Clinical Pharmacology, 2023, v. 63, n. 12, p. 1387, doi. 10.1002/jcph.2334
    By:
    • Bradley, John S.;
    • Makieieva, Nataliia;
    • Tøndel, Camilla;
    • Roilides, Emmanuel;
    • Kelly, Matthew S.;
    • Patel, Munjal;
    • Vaddady, Pavan;
    • Maniar, Alok;
    • Zhang, Ying;
    • Paschke, Amanda;
    • Chen, Luke F.
    Publication type:
    Article
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    Prospective, randomized, double-blind, Phase 2 dose-ranging study comparing efficacy and safety of imipenem/cilastatin plus relebactam with imipenem/cilastatin alone in patients with complicated urinary tract infections.

    Published in:
    Journal of Antimicrobial Chemotherapy (JAC), 2017, v. 72, n. 9, p. 2616, doi. 10.1093/jac/dkx139
    By:
    • Sims, Matthew;
    • Mariyanovski, Valeri;
    • McLeroth, Patrick;
    • Akers, Wayne;
    • Yu-Chieh Lee;
    • Brown, Michelle L.;
    • Jiejun Du;
    • Pedley, Alison;
    • Kartsonis, Nicholas A.;
    • Paschke, Amanda
    Publication type:
    Article
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    Combination therapy of cisplatin with cilastatin enables an increased dose of cisplatin, enhancing its antitumor effect by suppression of nephrotoxicity.

    Published in:
    Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80853-6
    By:
    • Arita, Masashi;
    • Watanabe, Satoshi;
    • Aoki, Nobumasa;
    • Kuwahara, Shoji;
    • Suzuki, Ryo;
    • Goto, Sawako;
    • Abe, Yuko;
    • Takahashi, Miho;
    • Sato, Miyuki;
    • Hokari, Satoshi;
    • Ohtsubo, Aya;
    • Shoji, Satoshi;
    • Nozaki, Koichiro;
    • Ichikawa, Kosuke;
    • Kondo, Rie;
    • Hayashi, Masachika;
    • Ohshima, Yasuyoshi;
    • Kabasawa, Hideyuki;
    • Hosojima, Michihiro;
    • Koya, Toshiyuki
    Publication type:
    Article
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    Early antibiotic treatment (prophylaxis) of septic complications in severe acute necrotizing pancreatitis: a prospective, randomized, multicenter study comparing two regimens with imipenem-cilastatin.

    Published in:
    2003
    By:
    • Maraví-Poma, Enrique;
    • Gener, Joan;
    • Alvarez-Lerma, Francisco;
    • Olaechea, Pedro;
    • Blanco, Armando;
    • Domínguez-Muñoz, J. Enrique;
    • Maraví-Poma, Enrique;
    • Domínguez-Muñoz, J Enrique;
    • Spanish Group for the Study of Septic Complications in Severe Acute Pancreatitis
    Publication type:
    journal article
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    Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice.

    Published in:
    Science Translational Medicine, 2016, v. 8, n. 339, p. 1, doi. 10.1126/scitranslmed.aaf2311
    By:
    • Yusuke Shono;
    • Docampo, Melissa D.;
    • Peled, Jonathan U.;
    • Perobelli, Suelen M.;
    • Velardi, Enrico;
    • Tsai, Jennifer J.;
    • Slingerland, Ann E.;
    • Smith, Odette M.;
    • Young, Lauren F.;
    • Gupta, Jyotsna;
    • Lieberman, Sophia R.;
    • Jay, Hillary V.;
    • Ahr, Katya F.;
    • Porosnicu Rodriguez, Kori A.;
    • Ke Xu;
    • Calarfiore, Marco;
    • Poeck, Hendrik;
    • Caballero, Silvia;
    • Devlin, Sean M.;
    • Rapaport, Franck
    Publication type:
    Article
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    Randomized, Double-blind, Multicenter Trial Comparing Efficacy and Safety of Imipenem/Cilastatin/Relebactam Versus Piperacillin/Tazobactam in Adults With Hospital-acquired or Ventilator-associated Bacterial Pneumonia (RESTORE-IMI 2 Study).

    Published in:
    Clinical Infectious Diseases, 2021, v. 73, n. 11, p. e4539, doi. 10.1093/cid/ciaa803
    By:
    • Titov, Ivan;
    • Wunderink, Richard G;
    • Roquilly, Antoine;
    • Gonzalez, Daniel Rodríguez;
    • David-Wang, Aileen;
    • Boucher, Helen W;
    • Kaye, Keith S;
    • Losada, Maria C;
    • Du, Jiejun;
    • Tipping, Robert;
    • Rizk, Matthew L;
    • Patel, Munjal;
    • Brown, Michelle L;
    • Young, Katherine;
    • Kartsonis, Nicholas A;
    • Butterton, Joan R;
    • Paschke, Amanda;
    • Chen, Luke F
    Publication type:
    Article
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