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Title

The Never Ending Struggle Against Development of Drug Resistance.

Authors

Daskapan, Alper; Stienstra, Ymkje; Akkerman, Onno W.; de Lange, Wiel C. M.; Kosterink, Jos G. W.; van der Werf, Tjip S.; Alffenaar, Jan-Willem C.; Narendran, Gopalan; Swaminathan, Soumya

Abstract

The article discusses struggle faced by development of drug resistance. It states that human immunodeficiency virus (HIV) patients who receive weekly anti tuberculosis therapy are at higher risk of acquired rifampicin resistance and showed that cotrimoxazole was active against tuberculosis and increased efficacy of rifampicin treatment. It mentions that therapeutic drug monitoring (TDM) joined with drug awareness testing may help to develop treatment in patients.

Subjects

DRUG resistance; THERAPEUTICS; HIV infections; RIFAMPIN; CO-trimoxazole; DRUG monitoring

Publication

Clinical Infectious Diseases, 2015, Vol 61, Issue 1, p137

ISSN

1058-4838

Publication type

Academic Journal

DOI

10.1093/cid/civ238

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