Title: Maternal and Neonatal Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Neutralization After Antenatal Messenger RNA Vaccination.
Authors: Rottenstreich, Amihai; Vorontsov, Olesya; Alfi, Or; Zarbiv, Gila; Oiknine-Djian, Esther; Zigron, Roy; Kleinstern, Geffen; Mandelboim, Michal; Porat, Shay; Wolf, Dana G
Abstract: We evaluated the neutralization efficiency against SARS-CoV-2 Omicron variant in maternal and cord blood sera after antenatal BNT162b2 vaccination. Neutralizing antibodies against Omicron were lacking at the time of delivery after 2-dose vaccination. A third booster dose was essential in building neutralizing antibody capacity against Omicron among mothers and neonates.
Subjects: SARS-CoV-2; IMMUNIZATION; MATERNAL-fetal exchange; COVID-19 vaccines; GENETIC variation; CORD blood; NEUTRALIZATION tests; PRENATAL care; VIRAL antibodies; DELIVERY (Obstetrics)
Publication: Clinical Infectious Diseases, 2022, Vol 75, Issue 11, p2023
ISSN: 1058-4838
Publication type: Academic Journal
DOI: 10.1093/cid/ciac395

Maternal and Neonatal Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant Neutralization After Antenatal Messenger RNA Vaccination.

Rottenstreich, Amihai; Vorontsov, Olesya; Alfi, Or; Zarbiv, Gila; Oiknine-Djian, Esther; Zigron, Roy; Kleinstern, Geffen; Mandelboim, Michal; Porat, Shay; Wolf, Dana G