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Title

Efficient Maternofetal Transplacental Transfer of Anti- Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Spike Antibodies After Antenatal SARS-CoV-2 BNT162b2 Messenger RNA Vaccination.

Authors

Rottenstreich, Amihai; Zarbiv, Gila; Oiknine-Djian, Esther; Zigron, Roy; Wolf, Dana G; Porat, Shay

Abstract

Maternal and cord blood sera were collected from 20 parturients who received the BNT162b2 vaccine. All women and infants were positive for anti S- and anti-receptor binding domain antibody–specific immunoglobulin G. Cord blood antibody concentrations were correlated to maternal levels and to time since vaccination. Antenatal severe acute respiratory syndrome coronavirus 2 vaccination may provide maternal and neonatal protection.

Subjects

MOTHERS; SARS-CoV-2; MATERNAL-fetal exchange; IMMUNIZATION; IMMUNOGLOBULINS; COVID-19 vaccines; CORD blood; MESSENGER RNA; PRENATAL care; VIRAL antibodies

Publication

Clinical Infectious Diseases, 2021, Vol 73, Issue 10, p1909

ISSN

1058-4838

Publication type

Academic Journal

DOI

10.1093/cid/ciab266

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