Pachydermoperiostosis: cosmetic implications in a multisystem genetic condition.

Dickens, James W; Lim, Kian Wah; Roy, Matthew; Wainman, Hannah

The article discusses a case of a 17-year-old boy with pachydermoperiostosis (PDP), a rare genetic condition characterized by digital clubbing, periostosis of long bones, and skin thickening. The patient presented with significant joint enlargement, cutis verticis gyrata, and acne, leading to a diagnosis of PDP through genetic testing. Treatment options for the arthralgia and dermatological manifestations of PDP were explored, highlighting the need for a multidisciplinary approach in managing such complex conditions. The article emphasizes the importance of early recognition of dermatological signs in systemic conditions like PDP and calls for further research into the medical management of its cutaneous features.

JOINT pain; NON-small-cell lung carcinoma; JOINTS (Anatomy); INFLAMMATORY bowel diseases; BOTULINUM toxin

Clinical & Experimental Dermatology, 2025, Vol 50, Issue 1, p240

0307-6938

Academic Journal

10.1093/ced/llae337