Results
Title

How useful is chest X-ray in addition to routine QuantiFERON® in the detection of latent tuberculosis prior to biologics?

Authors

Kearney, Niamh; Aslam, Fawad; Boyd, Grace; Boylan, Natasha; Laverty, Emma; O'Hare, Rosie; Campbell, Victoria; Hoey, Susannah; O'Kane, Donal

Abstract

The study in the Clinical & Experimental Dermatology journal focused on the utility of chest X-rays in addition to QuantiFERON testing for detecting latent tuberculosis in patients before starting biologic therapy. The research found that QuantiFERON was highly sensitive in detecting LTBI, while chest X-rays were less effective and led to additional imaging requirements. The study recommended considering QuantiFERON alone for screening dermatology patients with a low pretest probability to reduce the burden of care and save costs for healthcare services.

Subjects

LATENT tuberculosis; CLINICAL trials; HIDRADENITIS suppurativa; CHEST X rays; IONIZING radiation

Publication

Clinical & Experimental Dermatology, 2024, Vol 49, Issue 12, p1691

ISSN

0307-6938

Publication type

Academic Journal

DOI

10.1093/ced/llae258