Works matching DE "ATAXIA telangiectasia mutated protein"

Results: 198

Skin Fibroblasts from Individuals Self-Diagnosed as Electrosensitive Reveal Two Distinct Subsets with Delayed Nucleoshuttling of the ATM Protein in Common.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 10, p. 4792, doi. 10.3390/ijms26104792

By:

Sonzogni, Laurène;
Al-Choboq, Joëlle;
Combemale, Patrick;
Massardier-Pilonchéry, Amélie;
Bouchet, Audrey;
May, Philippe;
Doré, Jean-François;
Debouzy, Jean-Claude;
Bourguignon, Michel;
Dréan, Yves Le;
Foray, Nicolas

Publication type:

Article

UBQLN4 promotes non-homologous end joining by repressing DNA end-resection.

Published in:

Molecular & Cellular Oncology, 2019, v. 6, n. 2, p. 1, doi. 10.1080/23723556.2019.1575692

By:

Jachimowicz, Ron D.;
Reinhardt, H. Christian

Publication type:

Article

The effect of ionizing radiation and glucocorticoid induced tumor necrosis factor ligand (GITRL) expression in basal-like breast cancer cells.

Published in:

Turkish Journal of Immunology, 2016, v. 4, p. 69

By:

Uluata Dayanç, Bengisu;
Esendagli, Gunes;
Dayanç, Barış Emre

Publication type:

Article

ATM controls meiotic DNA double-strand break formation and recombination and affects synaptonemal complex organization in plants.

Published in:

Plant Cell, 2021, v. 33, n. 5, p. 1633, doi. 10.1093/plcell/koab045

By:

Kurzbauer, Marie-Therese;
Janisiw, Michael Peter;
Paulin, Luis F;
Mota, Ignacio Prusén;
Tomanov, Konstantin;
Krsicka, Ondrej;
Haeseler, Arndt von;
Schubert, Veit;
Schlögelhofer, Peter

Publication type:

Article

Down-expression of poly(ADP-ribose) polymerase in p53-regulated pancreatic cancer cells.

Published in:

Oncology Letters, 2018, v. 15, n. 2, p. 1943, doi. 10.3892/ol.2017.7500

By:

Hou, Zhenyu;
Cui, Yunfeng;
Xing, Huizhi;
Mu, Xiaoyan

Publication type:

Article

Expression and clinical significance of ATM and PUMA gene in patients with colorectal cancer.

Published in:

Oncology Letters, 2017, v. 14, n. 6, p. 7825, doi. 10.3892/ol.2017.7181

By:

Hui Xiong;
Jiangnan Zhang

Publication type:

Article

Japanese apricot extract (MK615) potentiates bendamustine-induced apoptosis via impairment of the DNA damage response in lymphoma cells.

Published in:

Oncology Letters, 2017, v. 14, n. 1, p. 792, doi. 10.3892/ol.2017.6219

By:

MASAYA INOUE;
YOSHIO HONMA;
JUNJI SUZUMIYA;
TAKESHI URANO

Publication type:

Article

Endonuclease G initiates DNA rearrangements at the MLL breakpoint cluster upon replication stress.

Published in:

Oncogene, 2015, v. 34, n. 26, p. 3391, doi. 10.1038/onc.2014.268

By:

Gole, B;
Baumann, C;
Mian, E;
Ireno, C I;
Wiesmüller, L

Publication type:

Article

The dual-acting chemotherapeutic agent Alchemix induces cell death independently of ATM and p53.

Published in:

Oncogene, 2015, v. 34, n. 25, p. 3336, doi. 10.1038/onc.2014.266

By:

Thomas, A;
Perry, T;
Berhane, S;
Oldreive, C;
Zlatanou, A;
Williams, L R;
Weston, V J;
Stankovic, T;
Kearns, P;
Pors, K;
Grand, R J;
Stewart, G S

Publication type:

Article

BMI1 attenuates etoposide-induced G2/M checkpoints via reducing ATM activation.

Published in:

Oncogene, 2015, v. 34, n. 23, p. 3063, doi. 10.1038/onc.2014.235

By:

Wei, F;
Ojo, D;
Lin, X;
Wong, N;
He, L;
Yan, J;
Xu, S;
Major, P;
Tang, D

Publication type:

Article

CHK1 overexpression in T-cell acute lymphoblastic leukemia is essential for proliferation and survival by preventing excessive replication stress.

Published in:

Oncogene, 2015, v. 34, n. 23, p. 2978, doi. 10.1038/onc.2014.248

By:

Sarmento, L M;
Póvoa, V;
Nascimento, R;
Real, G;
Antunes, I;
Martins, L R;
Moita, C;
Alves, P M;
Abecasis, M;
Moita, L F;
Parkhouse, R M E;
Meijerink, J P P;
Barata, J T

Publication type:

Article

TACC3 deregulates the DNA damage response and confers sensitivity to radiation and PARP inhibition.

Published in:

Oncogene, 2015, v. 34, n. 13, p. 1667, doi. 10.1038/onc.2014.105

By:

Ha, G-H;
Kim, J-L;
Petersson, A;
Oh, S;
Denning, M F;
Patel, T;
Breuer, E-K

Publication type:

Article

ATM-mediated phosphorylation of the chromatin remodeling enzyme BRG1 modulates DNA double-strand break repair.

Published in:

Oncogene, 2015, v. 34, n. 3, p. 303, doi. 10.1038/onc.2013.556

By:

Kwon, S-J;
Park, J-H;
Park, E-J;
Lee, S-A;
Lee, H-S;
Kang, S W;
Kwon, J

Publication type:

Article

The tumor suppressor, TAX1BP2, is a novel substrate of ATM kinase.

Published in:

Oncogene, 2014, v. 33, n. 45, p. 5303, doi. 10.1038/onc.2013.481

By:

Lai, W L;
Hung, W Y;
Ching, Y P

Publication type:

Article

ATM signalling and cancer.

Published in:

Oncogene, 2014, v. 33, n. 26, p. 3351, doi. 10.1038/onc.2013.275

By:

Cremona, C A;
Behrens, A

Publication type:

Article

Cell Death and Survival Pathways Involving ATM Protein Kinase.

Published in:

Genes, 2021, v. 12, n. 10, p. 1581, doi. 10.3390/genes12101581

By:

Aki, Toshihiko;
Uemura, Koichi

Publication type:

Article

Mechanisms Underlying the Suppression of Chromosome Rearrangements by Ataxia-Telangiectasia Mutated.

Published in:

Genes, 2021, v. 12, n. 8, p. 1232, doi. 10.3390/genes12081232

By:

Yamauchi, Motohiro

Publication type:

Article

Mec1/ATR, the Program Manager of Nucleic Acids Inc.

Published in:

Genes, 2017, v. 8, n. 1, p. 10, doi. 10.3390/genes8010010

By:

Feng, Wenyi

Publication type:

Article

The medicinal fungus Antrodia cinnamomea regulates DNA repair and enhances the radiosensitivity of human esophageal cancer cells.

Published in:

OncoTargets & Therapy, 2016, v. 9, p. 6651, doi. 10.2147/OTT.S96355

By:

Yu-Ming Liu;
Yu-Kuo Liu;
Ling-Wei Wang;
Yu-Chuen Huang;
Pin-I Huang;
Tung-Hu Tsai;
Yu-Jen Chen

Publication type:

Article

Downregulated Ku70 and ATM associated to poor prognosis in colorectal cancer among Chinese patients.

Published in:

OncoTargets & Therapy, 2014, v. 7, p. 1955, doi. 10.2147/OTT.S67814

By:

Yuanfang Lu;
Jingyan Gao;
Yuanming Lu

Publication type:

Article

Characterization of Glioma Stem Cells Through Multiple Stem Cell Markers and Their Specific Sensitization to Double-Strand Break-Inducing Agents by Pharmacological Inhibition of Ataxia Telangiectasia Mutated Protein.

Published in:

Brain Pathology, 2012, v. 22, n. 5, p. 677, doi. 10.1111/j.1750-3639.2012.00566.x

By:

Raso, Alessandro;
Vecchio, Donatella;
Cappelli, Enrico;
Ropolo, Monica;
Poggi, Alessandro;
Nozza, Paolo;
Biassoni, Roberto;
Mascelli, Samantha;
Capra, Valeria;
Kalfas, Fotios;
Severi, Paolo;
Frosina, Guido

Publication type:

Article

Pathological neoangiogenesis depends on oxidative stress regulation by ATM.

Published in:

Nature Medicine, 2012, v. 18, n. 8, p. 1208, doi. 10.1038/nm.2846

By:

Okuno, Yuji;
Nakamura-Ishizu, Ayako;
Otsu, Kinya;
Suda, Toshio;
Kubota, Yoshiaki

Publication type:

Article

Nuclear accumulation of HDAC4 in ATM deficiency promotes neurodegeneration in ataxia telangiectasia.

Published in:

Nature Medicine, 2012, v. 18, n. 5, p. 783, doi. 10.1038/nm.2709

By:

Li, Jiali;
Chen, Jianmin;
Ricupero, Christopher L;
Hart, Ronald P;
Schwartz, Melanie S;
Kusnecov, Alexander;
Herrup, Karl

Publication type:

Article

Influence of Individual Radiosensitivity on the Hormesis Phenomenon: Toward a Mechanistic Explanation Based on the Nucleoshuttling of ATM Protein.

Published in:

Dose-Response, 2020, v. 18, n. 2, p. 1, doi. 10.1177/1559325820913784

By:

Devic, Clément;
Ferlazzo, Mélanie L.;
Berthel, Elise;
Foray, Nicolas

Publication type:

Article

RBM17 Promotes the Chemoresistance of Oral Squamous Cancer Cells Through Checkpoint Kinase 1.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 7, p. 3127, doi. 10.3390/ijms26073127

By:

Nakahara, Miyuka;
Arai, Ryosuke;
Tokuoka, Isao;
Fukumura, Kazuhiro;
Mayeda, Akila;
Yashiro, Masakazu;
Nakahara, Hirokazu

Publication type:

Article

Activation of ATM kinase by ROS generated during ionophore-induced mitophagy in human T and B cell malignancies.

Published in:

Molecular & Cellular Biochemistry, 2021, v. 476, n. 1, p. 417, doi. 10.1007/s11010-020-03917-1

By:

Sarkar, Aloke;
Gandhi, Varsha

Publication type:

Article

The involvement of c-Myc in the DNA double-strand break repair via regulating radiation-induced phosphorylation of ATM and DNA-PKcs activity.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 406, n. 1/2, p. 43, doi. 10.1007/s11010-015-2422-2

By:

Cui, Fengmei;
Chen, Qiu;
Song, Man;
Shang, Zengfu;
Zhu, Wei;
Cao, Jianping;
Zhou, Ping-Kun;
Fan, Rong;
He, Yongming;
Zhang, Shimeng;
Guan, Hua

Publication type:

Article

MHC class I chain-related molecule A and B expression is upregulated by cisplatin and associated with good prognosis in patients with non-small cell lung cancer.

Published in:

Cancer Immunology, Immunotherapy, 2016, v. 65, n. 5, p. 499, doi. 10.1007/s00262-016-1814-9

By:

Okita, Riki;
Yukawa, Takuro;
Nojima, Yuji;
Maeda, Ai;
Saisho, Shinsuke;
Shimizu, Katsuhiko;
Nakata, Masao

Publication type:

Article

The core spliceosome as target and effector of non-canonical ATM signalling.

Published in:

Nature, 2015, v. 523, n. 7558, p. 53, doi. 10.1038/nature14512

By:

Tresini, Maria;
Warmerdam, Daniël O.;
Kolovos, Petros;
Snijder, Loes;
Vrouwe, Mischa G.;
Demmers, Jeroen A. A.;
van IJcken, Wilfred F. J.;
Grosveld, Frank G.;
Medema, René H.;
Hoeijmakers, Jan H. J.;
Mullenders, Leon H. F.;
Vermeulen, Wim;
Marteijn, Jurgen A.

Publication type:

Article

Post-Integrational DNA Repair of HIV-1 Is Associated with Activation of the DNA-PK and ATM Cellular Protein Kinases and Phosphorylation of Their Targets.

Published in:

Biochemistry (00062979), 2024, v. 89, n. 6, p. 1122, doi. 10.1134/S0006297924060117

By:

Anisenko, Andrey N.;
Nefedova, Anastasiia A.;
Kireev, Igor I.;
Gottikh, Marina B.

Publication type:

Article

Kinase-dead ATM protein causes genomic instability and early embryonic lethality in mice.

Published in:

Journal of Cell Biology, 2012, v. 198, n. 3, p. 305, doi. 10.1083/jcb.201204098

By:

Yamamoto, Kenta;
Wang, Yunyue;
Jiang, Wenxia;
Liu, Xiangyu;
Dubois, Richard L.;
Lin, Chyuan-Sheng;
Ludwig, Thomas;
Bakkenist, Christopher J.;
Zha, Shan

Publication type:

Article

Analysis of Residual DSBs in Ataxia-Telangiectasia Lymphoblast Cells Initiating Apoptosis.

Published in:

BioMed Research International, 2016, v. 2016, p. 1, doi. 10.1155/2016/8279560

By:

Anglada, Teresa;
Terradas, Mariona;
Hernández, Laia;
Genescà, Anna;
Martín, Marta

Publication type:

Article

ATM Protein Kinase: Old and New Implications in Neuronal Pathways and Brain Circuitry.

Published in:

Cells (2073-4409), 2020, v. 9, n. 9, p. 1969, doi. 10.3390/cells9091969

By:

Pizzamiglio, Lara;
Focchi, Elisa;
Antonucci, Flavia

Publication type:

Article

ATM-activated autotaxin (ATX) propagates inflammation and DNA damage in lung epithelial cells: a new mode of action for silica-induced DNA damage?

Published in:

Carcinogenesis, 2017, v. 38, n. 12, p. 1196, doi. 10.1093/carcin/bgx100

By:

Huiyuan Zheng;
Högberg, Johan;
Stenius, Ulla

Publication type:

Article

Initiation of the ATM-Chk2 DNA damage response through the base excision repair.

Published in:

Carcinogenesis, 2015, v. 36, n. 8, p. 832, doi. 10.1093/carcin/bgv079

By:

Wen-Cheng Chou;
Ling-Yueh Hu;
Chia-Ni Hsiung;
Chen-Yang Shen

Publication type:

Article

Speckle-type POZ protein, SPOP, is involved in the DNA damage response.

Published in:

Carcinogenesis, 2014, v. 35, n. 8, p. 1691, doi. 10.1093/carcin/bgu022

By:

Zhang, Dan;
Wang, Haibo;
Sun, Mianen;
Yang, Jun;
Zhang, Wei;
Han, Suxia;
Xu, Bo

Publication type:

Article

p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM.

Published in:

Science Signaling, 2017, v. 10, n. 476, p. 1, doi. 10.1126/scisignal.aah6671

By:

Stewart-Ornstein, Jacob;
Lahav, Galit

Publication type:

Article

Effect of Single Nucleotide Polymorphism Rs189037 in ATM Gene on Risk of Lung Cancer in Chinese: A Case-Control Study.

Published in:

PLoS ONE, 2014, v. 9, n. 12, p. 1, doi. 10.1371/journal.pone.0115845

By:

Liu, Jing;
Wang, Xiaobo;
Ren, Yangwu;
Li, Xuelian;
Zhang, Xichen;
Zhou, Baosen

Publication type:

Article

A Novel ATM/TP53/p21-Mediated Checkpoint Only Activated by Chronic γ-Irradiation.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104279

By:

Cao, Lili;
Kawai, Hidehiko;
Sasatani, Megumi;
Iizuka, Daisuke;
Masuda, Yuji;
Inaba, Toshiya;
Suzuki, Keiji;
Ootsuyama, Akira;
Umata, Toshiyuki;
Kamiya, Kenji;
Suzuki, Fumio

Publication type:

Article

Deoxycytidine Kinase Augments ATM-Mediated DNA Repair and Contributes to Radiation Resistance.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104125

By:

Bunimovich, Yuri L.;
Nair-Gill, Evan;
Riedinger, Mireille;
McCracken, Melissa N.;
Cheng, Donghui;
McLaughlin, Jami;
Radu, Caius G.;
Witte, Owen N.

Publication type:

Article

Direct Activation of ATM by Resveratrol under Oxidizing Conditions.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0097969

By:

Lee, Ji-Hoon;
Guo, Zhi;
Myler, Logan R.;
Zheng, Suting;
Paull, Tanya T.

Publication type:

Article

Single Nucleotide Polymorphism in ATM Gene, Cooking Oil Fumes and Lung Adenocarcinoma Susceptibility in Chinese Female Non-Smokers: A Case-Control Study.

Published in:

PLoS ONE, 2014, v. 9, n. 5, p. 1, doi. 10.1371/journal.pone.0096911

By:

Shen, Li;
Yin, Zhihua;
Wu, Wei;
Ren, Yangwu;
Li, Xuelian;
Zhou, Baosen

Publication type:

Article

ATM Alters the Otherwise Robust Chromatin Mobility at Sites of DNA Double-Strand Breaks (DSBs) in Human Cells.

Published in:

PLoS ONE, 2014, v. 9, n. 3, p. 1, doi. 10.1371/journal.pone.0092640

By:

Becker, Annabelle;
Durante, Marco;
Taucher-Scholz, Gisela;
Jakob, Burkhard

Publication type:

Article

Deficiency of Ataxia Telangiectasia Mutated Kinase Modulates Cardiac Remodeling Following Myocardial Infarction: Involvement in Fibrosis and Apoptosis.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0083513

By:

Foster, Cerrone R.;
Daniel, Laura L.;
Daniels, Christopher R.;
Dalal, Suman;
Singh, Mahipal;
Singh, Krishna

Publication type:

Article

Mutation at Intronic Repeats of the Ataxia-Telangiectasia Mutated (ATM) Gene and ATM Protein Loss in Primary Gastric Cancer with Microsatellite Instability.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082769

By:

Kim, Hee Sung;
Choi, Seung Im;
Min, Hae Lim;
Kim, Min A.;
Kim, Woo Ho

Publication type:

Article

Nbn and Atm Cooperate in a Tissue and Developmental Stage-Specific Manner to Prevent Double Strand Breaks and Apoptosis in Developing Brain and Eye.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069209

By:

Rodrigues, Paulo M. G.;
Grigaravicius, Paulius;
Remus, Martina;
Cavalheiro, Gabriel R.;
Gomes, Anielle L.;
Martins, Mauricio R.;
Frappart, Lucien;
Reuss, David;
McKinnon, Peter J.;
von Deimling, Andreas;
Martins, Rodrigo A. P.;
Frappart, Pierre-Olivier

Publication type:

Article

UV-Induced Nuclear Import of XPA Is Mediated by Importin-α4 in An ATR-Dependent Manner.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068297

By:

Li, Zhengke;
Musich, Phillip R.;
Cartwright, Brian M.;
Wang, Hui;
Zou, Yue

Publication type:

Article

Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Protein Kinase Inhibition Is Synthetically Lethal in XRCC1 Deficient Ovarian Cancer Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0057098

By:

Sultana, Rebeka;
Abdel-Fatah, Tarek;
Perry, Christina;
Moseley, Paul;
Albarakti, Nada;
Mohan, Vivek;
Seedhouse, Claire;
Chan, Stephen;
Madhusudan, Srinivasan

Publication type:

Article

Phosphorylation of Daxx by ATM Contributes to DNA Damage-Induced p53 Activation.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055813

By:

Tang, Jun;
Agrawal, Trisha;
Cheng, Qian;
Qu, Like;
Brewer, Michael D.;
Chen, Jiandong;
Yang, Xiaolu

Publication type:

Article

Middle Infrared Radiation Induces G<sub>2</sub>/M Cell Cycle Arrest in A549 Lung Cancer Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0054117

By:

Hsin-Yi Chang;
Meng-Her Shih;
Hsuan-Cheng Huang;
Shang-Ru Tsai;
Hsueh-Fen Juan;
Si-Chen Lee

Publication type:

Article