Works matching Treatment of prion diseases

Results: 150

Pharmacokinetics of quinacrine in the treatment of prion disease.

Published in:

BMC Infectious Diseases, 2004, v. 4, n. 1, p. 53, doi. 10.1186/1471-2334-4-53

By:

Lotus Yung;
Yong Huang;
Lessard, Pierre;
Legname, Giuseppe;
Lin, Emil T.;
Baldwin, Michael;
Prusiner, Stanley B.;
Chongsuk Ryou;
Guglielmo, B. Joseph

Publication type:

Article

Treatment of Prion Disease with Heterologous Prion Proteins.

Published in:

PLoS ONE, 2015, v. 10, n. 7, p. 1, doi. 10.1371/journal.pone.0131993

By:

Skinner, Pamela J.;
Kim, Hyeon O.;
Bryant, Damani;
Kinzel, Nikilyn J.;
Reilly, Cavan;
Priola, Suzette A.;
Ward, Anne E.;
Goodman, Patricia A.;
Olson, Katherine;
Seelig, Davis M.

Publication type:

Article

Therapeutic effect of peripheral administration of an anti-prion protein antibody on mice infected with prions.

Published in:

Microbiology & Immunology, 2013, v. 57, n. 4, p. 288, doi. 10.1111/1348-0421.12037

By:

Ohsawa, Natsuo;
Song, Chang‐Hyun;
Suzuki, Akio;
Furuoka, Hidefumi;
Hasebe, Rie;
Horiuchi, Motohiro

Publication type:

Article

Effective Gene Therapy in a Mouse Model of Prion.

Published in:

PLoS ONE, 2008, v. 3, n. 7, p. 1, doi. 10.1371/journal.pone.0002773

By:

Toupet, Karine;
Compan, Valérie;
Crozet, Carole;
Mourton-Gilles, Chantal;
Mestre-Francés, Nadine;
Ibos, Françoise;
Corbeau, Pierre;
Verdier, Jean-Michel;
Perrier, Véronique

Publication type:

Article

Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway.

Published in:

International Journal of Molecular Sciences, 2019, v. 20, n. 5, p. 1144, doi. 10.3390/ijms20051144

By:

Shah, Syed Zahid Ali;
Zhao, Deming;
Taglialatela, Giulio;
Hussain, Tariq;
Dong, Haodi;
Sabir, Naveed;
Mangi, Mazhar Hussain;
Wu, Wei;
Lai, Mengyu;
Zhang, Xixi;
Duan, Yuhan;
Wang, Lu;
Zhou, Xiangmei;
Yang, Lifeng

Publication type:

Article

Continuous intraventricular infusion of pentosan polysulfate: Clinical trial against prion diseases.

Published in:

Neuropathology, 2009, v. 29, n. 5, p. 632, doi. 10.1111/j.1440-1789.2009.01058.x

By:

Tsuboi, Yoshio;
Doh-ura, Katsumi;
Yamada, Tatsuo

Publication type:

Article

Anti-Prion Activity of Brilliant Blue G.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037896

By:

Iwamaru, Yoshifumi;
Takenouchi, Takato;
Murayama, Yuichi;
Okada, Hiroyuki;
Imamura, Morikazu;
Shimizu, Yoshihisa;
Hashimoto, Makoto;
Mohri, Shirou;
Yokoyama, Takashi;
Kitani, Hiroshi

Publication type:

Article

The N-Terminal, Polybasic Region Is Critical for Prion Protein Neuroprotective Activity.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025675

By:

Turnbaugh, Jessie A.;
Westergard, Laura;
Unterberger, Ursula;
Biasini, Emiliano;
Harris, David A.

Publication type:

Article

Miscellaneous.

Published in:: Current Medical Literature: Neurology, 2008, v. 24, n. 3, p. 91
Publication type:: Article

Attempt to isolate subfraction of mouse mesenchymal stem cells and production of mesenchymal stem cells expressing anti-PrP antibodies.

Published in:

Japanese Journal of Veterinary Research, 2013, v. 61, n. 1/2, p. 74

By:

Hayashi, Ryo

Publication type:

Article

Ultraviolet-ozone treatment reduces levels of disease-associated prion protein and prion infectivity.

Published in:: BMC Research Notes, 2009, v. 2, p. 121, doi. 10.1186/1756-0500-2-121
Publication type:: Article

RNAi: a novel strategy for the treatment of prion diseases.

Published in:

Journal of Clinical Investigation, 2006, v. 116, n. 12, p. 3101, doi. 10.1172/JCI30663

By:

Qingzhong Kong

Publication type:

Article

Prevalence and Treatments of Movement Disorders in Prion Diseases: A Longitudinal Cohort Study.

Published in:

2022

By:

Sequeira, Danielle;
Nihat, Akin;
Mok, Tzehow;
Coysh, Thomas;
Rudge, Peter;
Collinge, John;
Mead, Simon

Publication type:

journal article

Activation of the unfolded protein response and granulovacuolar degeneration are not common features of human prion pathology.

Published in:

Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0383-7

By:

Wiersma, Vera I.;
van Hecke, Wim;
Scheper, Wiep;
van Osch, Martijn A. J.;
Hermsen, Will J. M.;
Rozemuller, Annemieke J. M.;
Hoozemans, Jeroen J. M.

Publication type:

Article

Alkylating Antitumor Drug Mechlorethamine Conceals A Structured PrP Domain and Inhibits in Vitro Prion Amplification.

Published in:

Journal of Toxicology & Environmental Health: Part A, 2011, v. 74, n. 22-24, p. 1493, doi. 10.1080/15287394.2011.618978

By:

Zhou, Xiaochen;
Bi, Hao;
Wong, Justin;
Shimoji, Miyuki;
Wang, Yifan;
Yuan, Jue;
Xiao, Xiangzhu;
Wang, Gong-Xian;
Zou, Wen-Quan

Publication type:

Article

Oral Treatment Targeting the Unfolded Protein Response Prevents Neurodegeneration and Clinical Disease in Prion-Infected Mice.

Published in:

Science Translational Medicine, 2013, v. 5, n. 206, p. 1, doi. 10.1126/scitranslmed.3006767

By:

Moreno, Julie A.;
Halliday, Mark;
Molloy, Colin;
Radford, Helois;
Verity, Nicholas;
Axten, Jeffrey M.;
Ortori, Catharine A.;
Willis, Anne E.;
Fischer, Peter M.;
Barrett, David A.;
Mallucci, Giovanna R.

Publication type:

Article

Sporadic Fatal Insomnia in Europe: Phenotypic Features and Diagnostic Challenges.

Published in:

2018

By:

Abu‐Rumeileh, Samir;
Redaelli, Veronica;
Baiardi, Simone;
Mackenzie, Graeme;
Windl, Otto;
Ritchie, Diane L.;
Didato, Giuseppe;
Hernandez‐Vara, Jorge;
Rossi, Marcello;
Capellari, Sabina;
Imperiale, Daniele;
Rizzone, Mario Giorgio;
Belotti, Alessia;
Sorbi, Sandro;
Rozemuller, Annemieke J. M.;
Cortelli, Pietro;
Gelpi, Ellen;
Will, Robert G.;
Zerr, Inga;
Giaccone, Giorgio

Publication type:

journal article

A Single Subcutaneous Injection of Cellulose Ethers Administered Long before Infection Confers Sustained Protection against Prion Diseases in Rodents.

Published in:

PLoS Pathogens, 2016, v. 12, n. 12, p. 1, doi. 10.1371/journal.ppat.1006045

By:

Teruya, Kenta;
Oguma, Ayumi;
Nishizawa, Keiko;
Kawata, Maki;
Sakasegawa, Yuji;
Kamitakahara, Hiroshi;
Doh-ura, Katsumi

Publication type:

Article

From Scientific Curiosity to Public Enemy Number One in Six Short Months.

Published in:

PLoS Pathogens, 2016, v. 12, n. 4, p. 1, doi. 10.1371/journal.ppat.1005371

By:

Mabbott, Neil A.

Publication type:

Article

Prion diseases and dental treatment: principles and practice of patients with/suspected or at-risk of CJD: Case reports.

Published in:

British Dental Journal, 2003, v. 195, n. 6, p. 319, doi. 10.1038/sj.bdj.4810542

By:

Smith, A.J.;
Sweeney, M.P.;
Bagg, J.

Publication type:

Article

Selective propagation of mouse-passaged scrapie prions with long incubation period from a mixed prion population using GT1-7 cells.

Published in:

PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0179317

By:

Miyazawa, Kohtaro;
Masujin, Kentaro;
Okada, Hiroyuki;
Matsuura, Yuichi;
Ushiki-Kaku, Yuko;
Yokoyama, Takashi

Publication type:

Article

Prion pathogenesis is unaltered in the absence of SIRPα-mediated "don't-eat-me" signaling.

Published in:

PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0177876

By:

Nuvolone, Mario;
Paolucci, Marta;
Sorce, Silvia;
Kana, Veronika;
Moos, Rita;
Matozaki, Takashi;
Aguzzi, Adriano

Publication type:

Article

In Vivo Longitudinal H MRS Study of Transgenic Mouse Models of Prion Disease in the Hippocampus and Cerebellum at 14.1 T.

Published in:

Neurochemical Research, 2015, v. 40, n. 12, p. 2639, doi. 10.1007/s11064-015-1643-9

By:

Cudalbu, Cristina;
Craveiro, Melanie;
Mlynárik, Vladimir;
Bremer, Juliane;
Aguzzi, Adriano;
Gruetter, Rolf

Publication type:

Article

Fatal familial insomnia with abnormal signals on routine MRI: a case report and literature review.

Published in:

2017

By:

Tingting Lu;
Yuhang Pan;
Lisheng Peng;
Feng Qin;
Xiaobo Sun;
Zhengqi Lu;
Wei Qiu;
Lu, Tingting;
Pan, Yuhang;
Peng, Lisheng;
Qin, Feng;
Sun, Xiaobo;
Lu, Zhengqi;
Qiu, Wei

Publication type:

journal article

Remarkable reductions of PAKs in the brain tissues of scrapie-infected rodent possibly linked closely with neuron loss.

Published in:

Medical Microbiology & Immunology, 2014, v. 203, n. 5, p. 291, doi. 10.1007/s00430-014-0342-5

By:

Meng, Ge;
Tian, Chan;
Wang, Hui;
Xu, Yin;
Zhang, Bao-Yun;
Shi, Qi;
Gao, Chen;
Chen, Cao;
Fan, Xue-Yu;
Wang, Jing;
Xiao, Kang;
Ren, Ke;
Xue, Ming-Ming;
Dong, Xiao-Ping

Publication type:

Article

Distribution of microRNA profiles in pre-clinical and clinical forms of murine and human prion disease.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-01868-x

By:

Cheng, Lesley;
Quek, Camelia;
Li, Xia;
Bellingham, Shayne A.;
Ellett, Laura J.;
Shambrook, Mitch;
Zafar, Saima;
Zerr, Inga;
Lawson, Victoria A.;
Hill, Andrew F.

Publication type:

Article

Targeting of poly(l-lysine) to organs that propagate prions.

Published in:

Journal of Bioactive & Compatible Polymers, 2014, v. 29, n. 5, p. 432, doi. 10.1177/0883911514542898

By:

Lee, Hye-Mi;
Ryou, Chongsuk

Publication type:

Article

NLRP3 inflammasome activation in macrophage cell lines by prion protein fibrils as the source of IL-1β and neuronal toxicity.

Published in:

Cellular & Molecular Life Sciences, 2012, v. 69, n. 24, p. 4215, doi. 10.1007/s00018-012-1140-0

By:

Hafner-Bratkovič, Iva;
Benčina, Mojca;
Fitzgerald, Katherine;
Golenbock, Douglas;
Jerala, Roman

Publication type:

Article

Is There Still Hope After Prions Have Spread Within the Brain?

Published in:

Journal of Infectious Diseases, 2011, v. 204, n. 7, p. 978, doi. 10.1093/infdis/jir487

By:

Carnaud, Claude

Publication type:

Article

Protein Folding Activity of the Ribosome (PFAR) — A Target for Antiprion Compounds.

Published in:

Viruses (1999-4915), 2014, v. 6, n. 10, p. 3907, doi. 10.3390/v6103907

By:

Banerjee, Debapriya;
Sanyal, Suparna

Publication type:

Article

A Discrete-Time Branching Process Model of Yeast Prion Curing Curves*.

Published in:

Mathematical Population Studies, 2013, v. 20, n. 1, p. 1, doi. 10.1080/08898480.2013.748566

By:

SINDI, SUZANNES.;
OLOFSSON, PETER

Publication type:

Article

P2-380: Identification and characterization of human autoantibodies that may be used for the treatment of prion diseases

Published in:

2008

By:

Du, Yansheng;
Wei, Xing;
He, Yongzheng;
Wei, Gang;
Hampel, Harald;
Dodel, Richard;
Farlow, Martin

Publication type:

Abstract

O4-04-02: Therapeutic effects of gene therapy in the late treatment of prion diseases

Published in:

2008

By:

Verdier, Jean-Michel;
Toupet, Karine;
Compan, Valérie;
Crozet, Carole;
Mestre-Frances, Nadine;
Corbeau, Pierre;
Perrier, Véronique

Publication type:

Abstract

Potential approaches for heterologous prion protein treatment of prion diseases.

Published in:

Prion, 2016, v. 10, n. 1, p. 18, doi. 10.1080/19336896.2015.1123372

By:

Seelig, Davis M.;
Goodman, Patricia A.;
Skinner, Pamela J.

Publication type:

Article

P.185: Quinacrine and its bioavailability in treatment of prion disease.

Published in:

Prion, 2014, v. 8, p. 112

By:

Safarik, Martin;
Mosko, Tibor;
Zawada, Zbigniew;
Dvorakova, Eva;
Holada, Karel;
Sebestik, Jaroslav

Publication type:

Article

Nanomedicine for prion disease treatment.

Published in:

Prion, 2013, v. 7, n. 3, p. 198, doi. 10.4161/pri.24431

By:

McCarthy, James M.;
Appelhans, Dietmar;
Tatzelt, Jörg;
Rogers, Mark S.

Publication type:

Article

Immunization treatment approaches in Alzheimer’s and prion diseases.

Published in:

Current Neurology & Neuroscience Reports, 2002, v. 2, n. 5, p. 400, doi. 10.1007/s11910-002-0065-7

By:

Wisniewski, Thomas;
Sigurdsson, Einar

Publication type:

Article

Cellulose ether treatment in vivo generates chronic wasting disease prions with reduced protease resistance and delayed disease progression.

Published in:

Journal of Neurochemistry, 2020, v. 152, n. 6, p. 727, doi. 10.1111/jnc.14877

By:

Hannaoui, Samia;
Arifin, Maria Immaculata;
Chang, Sheng Chun;
Yu, Jie;
Gopalakrishnan, Preetha;
Doh‐ura, Katsumi;
Schatzl, Hermann M.;
Gilch, Sabine

Publication type:

Article

Pharmacological Agents Targeting the Cellular Prion Protein.

Published in:

Pathogens, 2018, v. 7, n. 1, p. 27, doi. 10.3390/pathogens7010027

By:

Barreca, Maria Letizia;
Iraci, Nunzio;
Biggi, Silvia;
Cecchetti, Violetta;
Biasini, Emiliano

Publication type:

Article

Molecular Nanobiotechnological approaches for the detection and therapy of prion related diseases.

Published in:

Nano Biomedicine & Engineering, 2012, v. 4, n. 2, p. 50, doi. 10.5101/nbe.v4i2.p50-57

By:

Praseetha, P. K.;
Thampy, Anand S.;
Venugopalan, P.;
Chavali, Murthy S.

Publication type:

Article

2-Aminothiazoles with Improved Pharmacotherapeutic Properties for Treatment of Prion Disease.

Published in:

ChemMedChem, 2013, v. 8, n. 5, p. 847, doi. 10.1002/cmdc.201300007

By:

Li, Zhe;
Silber, B. Michael;
Rao, Satish;
Gever, Joel R.;
Bryant, Clifford;
Gallardo‐Godoy, Alejandra;
Dolghih, Elena;
Widjaja, Kartika;
Elepano, Manuel;
Jacobson, Matthew P.;
Prusiner, Stanley B.;
Renslo, Adam R.

Publication type:

Article

Dendrimers as therapeutic agents: a systematic review.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 8, p. 989, doi. 10.1211/jpp.61.08.0002

By:

Virendra Gajbhiye

Publication type:

Article

Prion diseases: current understanding of epidemiology and pathogenesis, and therapeutic advances.

Published in:

2006

By:

Caramelli, Maria;
Ru, Giuseppe;
Acutis, Pierluigi;
Forloni, Gianluigi

Publication type:

journal article

Prions, Parkinson's disease and the search for a new generation of treatments.

Published in:

Progress in Neurology & Psychiatry, 2011, v. 15, n. 6, p. 26, doi. 10.1002/pnp.219

By:

Greener, Mark

Publication type:

Article

Proceedings of 2nd Annual Charles River World Congress: Lessons Learned from Rare Disease and Personalized Medicine Approaches.

Published in:: 2018
Publication type:: Abstract

Prospects for the Pharmacological Treatment of Human Prion Diseases.

Published in:

CNS Drugs, 1998, v. 10, n. 2, p. 83, doi. 10.2165/00023210-199810020-00001

By:

Adjou, K.T.;
deslys, J-P.;
demaimay, R.;
Seman, M.;
Dormont, D.

Publication type:

Article

“Big data” gets personal.

Published in:

Science Translational Medicine, 2016, v. 8, n. 322, p. 1, doi. 10.1126/scitranslmed.aad9460

By:

Lebo, Matthew S.;
Sutti, Sheila;
Green, Robert C.

Publication type:

Article

The anti-fibrillogenic activity of tetracyclines on PrP 106–126: a 3D-QSAR study.

Published in:

Journal of Molecular Modeling, 2008, v. 14, n. 10, p. 987, doi. 10.1007/s00894-008-0348-2

By:

Ugo Cosentino;
Demetrio Pitea;
Giorgio Moro;
Gloria Saracino;
Pietro Caria;
Rosaria Varì;
Laura Colombo;
Gianluigi Forloni;
Fabrizio Tagliavini;
Mario Salmona

Publication type:

Article

Human prion diseases: progress in clinical trials.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 4, p. 996, doi. 10.1093/brain/awt075

By:

Zerr, Inga

Publication type:

Article

The Medical Research Council Prion Disease Rating Scale: a new outcome measure for prion disease therapeutic trials developed and validated using systematic observational studies.

Published in:

Brain: A Journal of Neurology, 2013, v. 136, n. 4, p. 1116, doi. 10.1093/brain/awt048

By:

Thompson, Andrew G.B.;
Lowe, Jessica;
Fox, Zoe;
Lukic, Ana;
Porter, Marie-Claire;
Ford, Liz;
Gorham, Michele;
Gopalakrishnan, Gosala S.;
Rudge, Peter;
Walker, A. Sarah;
Collinge, John;
Mead, Simon

Publication type:

Article