Works matching AU Yamanashi, Yuji

Results: 33

Pan-cancer and cross-population genome-wide association studies dissect shared genetic backgrounds underlying carcinogenesis.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-39136-7

By:

Sato, Go;
Shirai, Yuya;
Namba, Shinichi;
Edahiro, Ryuya;
Sonehara, Kyuto;
Hata, Tsuyoshi;
Uemura, Mamoru;
the Biobank Japan Project;
Yamanashi, Yuji;
Furukawa, Yoichi;
Morisaki, Takayuki;
Murakami, Yoshinori;
Kamatani, Yoichiro;
Muto, Kaori;
Nagai, Akiko;
Obara, Wataru;
Yamaji, Ken;
Takahashi, Kazuhisa;
Asai, Satoshi;
Takahashi, Yasuo

Publication type:

Article

Dok-7 Activates the Muscle Receptor Kinase MuSK and Shapes Synapse Formation.

Published in:

Science Signaling, 2009, v. 2, n. 59, p. 1, doi. 10.1126/scisignal.2000113

By:

Inoue, Akane;
Setoguchi, Kiyoko;
Matsubara, Yosuke;
Okada, Kumiko;
Sato, Nozomi;
Iwakura, Yoichiro;
Higuchi, Osamu;
Yamanashi, Yuji

Publication type:

Article

Critical role of Frizzled1 in age-related alterations of Wnt/β-catenin signal in myogenic cells during differentiation.

Published in:

Genes to Cells, 2014, v. 19, n. 4, p. 287, doi. 10.1111/gtc.12132

By:

Doi, Ryosuke;
Endo, Mitsuharu;
Yamakoshi, Kimi;
Yamanashi, Yuji;
Nishita, Michiru;
Fukada, So‐ichiro;
Minami, Yasuhiro

Publication type:

Article

Dok adaptors play anti-inflammatory roles in pulmonary homeostasis.

Published in:

Genes to Cells, 2013, v. 18, n. 1, p. 56, doi. 10.1111/gtc.12016

By:

Mashima, Ryuichi;
Arimura, Sumimasa;
Kajikawa, Shuhei;
Oda, Hideaki;
Nakae, Susumu;
Yamanashi, Yuji

Publication type:

Article

The adaptor-like protein ROG-1 is required for activation of the Ras-MAP kinase pathway and meiotic cell cycle progression in Caenorhabditis elegans.

Published in:

Genes to Cells, 2007, v. 12, n. 3, p. 407, doi. 10.1111/j.1365-2443.2007.01061.x

By:

Matsubara, Yosuke;
Kawasaki, Ichiro;
Urushiyama, Seiichi;
Yasuda, Tomoharu;
Shirakata, Masaki;
Iino, Yuichi;
Shibuya, Hiroshi;
Yamanashi, Yuji

Publication type:

Article

Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases.

Published in:

Genes to Cells, 2006, v. 11, n. 2, p. 143, doi. 10.1111/j.1365-2443.2006.00926.x

By:

Honma, Miyuki;
Higuchi, Osamu;
Shirakata, Masaki;
Yasuda, Tomoharu;
Shibuya, Hiroshi;
Iemura, Shun-ichiro;
Natsume, Tohru;
Yamanashi, Yuji

Publication type:

Article

Dok-1 tyrosine residues at 336 and 340 are essential for the negative regulation of Ras-Erk signalling, but dispensable for rasGAP-binding.

Published in:

Genes to Cells, 2004, v. 9, n. 6, p. 601, doi. 10.1111/j.1356-9597.2004.00748.x

By:

Shinohara, Hisaaki;
Yasuda, Tomoharu;
Yamanashi, Yuji

Publication type:

Article

DOK7 gene therapy enhances motor activity and life span in ALS model mice.

Published in:

EMBO Molecular Medicine, 2017, v. 9, n. 7, p. 880, doi. 10.15252/emmm.201607298

By:

Miyoshi, Sadanori;
Tezuka, Tohru;
Arimura, Sumimasa;
Tomono, Taro;
Okada, Takashi;
Yamanashi, Yuji

Publication type:

Article

Autoantibodies to low-density lipoprotein receptor-related protein 4 in myasthenia gravis.

Published in:

Annals of Neurology, 2011, v. 69, n. 2, p. 418, doi. 10.1002/ana.22312

By:

Higuchi, Osamu;
Hamuro, Johko;
Motomura, Masakatsu;
Yamanashi, Yuji

Publication type:

Article

Dok-1 and Dok-2 deficiency induces osteopenia via activation of osteoclasts.

Published in:

Journal of Cellular Physiology, 2011, v. 226, n. 12, p. 3087, doi. 10.1002/jcp.22909

By:

Kawamata, Aya;
Inoue, Akane;
Miyajima, Daisuke;
Hemmi, Hiroaki;
Mashima, Ryuichi;
Hayata, Tadayoshi;
Ezura, Yoichi;
Amagasa, Teruo;
Yamanashi, Yuji;
Noda, Masaki

Publication type:

Article

Population-specific reference panel improves imputation quality for genome-wide association studies conducted on the Japanese population.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07338-4

By:

Flanagan, Jack;
Liu, Xiaoxi;
Ortega-Reyes, David;
Tomizuka, Kohei;
Matoba, Nana;
Akiyama, Masato;
Koido, Masaru;
Ishigaki, Kazuyoshi;
Ashikawa, Kyota;
Takata, Sadaaki;
Shi, MingYang;
Aoi, Tomomi;
Momozawa, Yukihide;
Ito, Kaoru;
Murakami, Yoshinori;
Matsuda, Koichi;
The Biobank Japan Project;
Yamanashi, Yuji;
Furukawa, Yoichi;
Morisaki, Takayuki

Publication type:

Article

Genome-wide association studies for pelvic organ prolapse in the Japanese population.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-06875-2

By:

Matsunami, Masatoshi;
Imamura, Minako;
Ashikari, Asuka;
Liu, Xiaoxi;
Tomizuka, Kohei;
Hikino, Keiko;
Miwa, Kosei;
Kadekawa, Katsumi;
Suda, Tetsuji;
The Biobank Japan project;
Morisaki, Takayuki;
Okada, Yukinori;
Kamatani, Yoichiro;
Muto, Kaori;
Nagai, Akiko;
Sagiya, Yoji;
Kumasaka, Natsuhiko;
Furukawa, Yoichi;
Yamanashi, Yuji;
Murakami, Yoshinori

Publication type:

Article

Effect of salbutamol on neuromuscular junction function and structure in a mouse model of DOK7 congenital myasthenia.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 14, p. 2325, doi. 10.1093/hmg/ddaa116

By:

Webster, Richard G;
Vanhaesebrouck, An E;
Maxwell, Susan E;
Cossins, Judith A;
Liu, Weiwei;
Ueta, Ryo;
Yamanashi, Yuji;
Beeson, David M W

Publication type:

Article

Genetic legacy of ancient hunter-gatherer Jomon in Japanese populations.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-54052-0

By:

Yamamoto, Kenichi;
Namba, Shinichi;
Sonehara, Kyuto;
Suzuki, Ken;
Sakaue, Saori;
Cooke, Niall P.;
Higashiue, Shinichi;
Kobayashi, Shuzo;
Afuso, Hisaaki;
Matsuura, Kosho;
Mitsumoto, Yojiro;
Fujita, Yasuhiko;
Tokuda, Torao;
the Biobank Japan Project;
Yamanashi, Yuji;
Furukawa, Yoichi;
Morisaki, Takayuki;
Murakami, Yoshinori;
Kamatani, Yoichiro;
Muto, Kaori

Publication type:

Article

Common and rare genetic variants predisposing females to unexplained recurrent pregnancy loss.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49993-5

By:

Sonehara, Kyuto;
Yano, Yoshitaka;
Naito, Tatsuhiko;
Goto, Shinobu;
Yoshihara, Hiroyuki;
Otani, Takahiro;
Ozawa, Fumiko;
Kitaori, Tamao;
Yamanashi, Yuji;
Furukawa, Yoichi;
Morisaki, Takayuki;
Murakami, Yoshinori;
Kamatani, Yoichiro;
Muto, Kaori;
Nagai, Akiko;
Nakamura, Yusuke;
Obara, Wataru;
Yamaji, Ken;
Takahashi, Kazuhisa;
Asai, Satoshi

Publication type:

Article

A variant in HMMR/HMMR-AS1 is associated with serum alanine aminotransferase levels in the Ryukyu population.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-90195-w

By:

Ohyama, Noriko;
Matsunami, Masatoshi;
Imamura, Minako;
Yoshida, Akihiro;
Javed, Azeem;
Liu, Xiaoxi;
Kimura, Ryosuke;
Matsuda, Koichi;
Morisaki, Takayuki;
Okada, Yukinori;
Kamatani, Yoichiro;
Muto, Kaori;
Nagai, Akiko;
Sagiya, Yoji;
Kumasaka, Natsuhiko;
Furukawa, Yoichi;
Yamanashi, Yuji;
Murakami, Yoshinori;
Nakamura, Yusuke;
Obara, Wataru

Publication type:

Article

Clinical features of the DOK7 neuromuscular junction synaptopathy.

Published in:

Brain: A Journal of Neurology, 2007, v. 130, n. 6, p. 1507, doi. 10.1093/brain/awm072

By:

Jacqueline Palace;
Daniel Lashley;
John Newsom-Davis;
Judy Cossins;
Susan Maxwell;
Robin Kennett;
Sandeep Jayawant;
Yuji Yamanashi;
David Beeson

Publication type:

Article

Dok1 mediates high-fat diet–induced adipocyte hypertrophy and obesity through modulation of PPAR-γ phosphorylation.

Published in:

Nature Medicine, 2008, v. 14, n. 2, p. 188, doi. 10.1038/nm1706

By:

Hosooka, Tetsuya;
Noguchi, Tetsuya;
Kotani, Ko;
Nakamura, Takehiro;
Sakaue, Hiroshi;
Inoue, Hiroshi;
Ogawa, Wataru;
Tobimatsu, Kazutoshi;
Takazawa, Kazuo;
Sakai, Mashito;
Matsuki, Yasushi;
Hiramatsu, Ryuji;
Yasuda, Tomoharu;
Lazar, Mitchell A;
Yamanashi, Yuji;
Kasuga, Masato

Publication type:

Article

Dok-1 is a Positive Regulator of IL-4 Signalling and IgE Response.

Published in:

Journal of Biochemistry, 2007, v. 142, n. 2, p. 257, doi. 10.1093/jb/mvm127

By:

Inoue, Akane;
Yasuda, Tomoharu;
Yamamoto, Tadashi;
Yamanashi, Yuji

Publication type:

Article

The carboxyl-terminal region of Dok-7 plays a key, but not essential, role in activation of muscle-specific receptor kinase MuSK and neuromuscular synapse formation.

Published in:

Journal of Biochemistry, 2017, v. 161, n. 3, p. 269, doi. 10.1093/jb/mvw073

By:

Ryo Ueta;
Tohru Tezuka;
Yosuke Izawa;
Sadanori Miyoshi;
Satoru Nagatoishi;
Kouhei Tsumoto;
Yuji Yamanashi

Publication type:

Article

Structural flexibility regulates phosphopeptide-binding activity of the tyrosine kinase binding domain of Cbl-c.

Published in:

Journal of Biochemistry, 2012, v. 152, n. 5, p. 487, doi. 10.1093/jb/mvs085

By:

Takeshita, Kohei;
Tezuka, Tohru;
Isozaki, Yukari;
Yamashita, Eiki;
Suzuki, Mamoru;
Kim, Minsoo;
Yamanashi, Yuji;
Yamamoto, Tadashi;
Nakagawa, Atsushi

Publication type:

Article

Activation of receptor protein-tyrosine kinases from the cytoplasmic compartment.

Published in:

Journal of Biochemistry, 2012, v. 151, n. 4, p. 353, doi. 10.1093/jb/mvs013

By:

Yamanashi, Yuji;
Tezuka, Tohru;
Yokoyama, Kazumasa

Publication type:

Article

Tyrosine phosphorylation of p62<sup>Dok</sup> induced by cell adhesion and insulin: possible role in cell migration.

Published in:

EMBO Journal, 1999, v. 18, n. 7, p. 1748, doi. 10.1093/emboj/18.7.1748

By:

Noguchi, Tetsuya;
Matozaki, Takashi;
Inagaki, Kenjiro;
Tsuda, Masahiro;
Fukunaga, Kaoru;
Kitamura, Yukari;
Kitamura, Tadahiro;
Shii, Kozui;
Yamanashi, Yuji;
Kasuga, Masato

Publication type:

Article

Loss of C/EBPδ enhances apoptosis of intestinal epithelial cells and exacerbates experimental colitis in mice.

Published in:

Genes to Cells, 2019, v. 24, n. 9, p. 619, doi. 10.1111/gtc.12711

By:

Jozawa, Hiroki;
Inoue‐Yamauchi, Akane;
Arimura, Sumimasa;
Yamanashi, Yuji

Publication type:

Article

Postnatal knockdown of dok-7 gene expression in mice causes structural defects in neuromuscular synapses and myasthenic pathology.

Published in:

Genes to Cells, 2016, v. 21, n. 6, p. 670, doi. 10.1111/gtc.12370

By:

Eguchi, Takahiro;
Tezuka, Tohru;
Miyoshi, Sadanori;
Yamanashi, Yuji

Publication type:

Article

Dok-1 and Dok-2 are negative regulators of T cell receptor signaling.

Published in:

International Immunology, 2007, v. 19, n. 4, p. 487, doi. 10.1093/intimm/dxm015

By:

Tomoharu Yasuda;
Kenji Bundo;
Ayako Hino;
Kazuho Honda;
Akane Inoue;
Masaki Shirakata;
Mitsujiro Osawa;
Toshiki Tamura;
Hideo Nariuchi;
Hideaki Oda;
Tadashi Yamamoto;
Yuji Yamanashi

Publication type:

Article

Human TUBG2 gene is expressed as two splice variant mRNA and involved in cell growth.

Published in:

FEBS Letters, 2016, v. 590, n. 8, p. 1053, doi. 10.1002/1873-3468.12163

By:

Ohashi, Tsubasa;
Yamamoto, Tadashi;
Yamanashi, Yuji;
Ohsugi, Miho

Publication type:

Article

Mesdc2 plays a key role in cell-surface expression of Lrp4 and postsynaptic specialization in myotubes.

Published in:

FEBS Letters, 2013, v. 587, n. 23, p. 3749, doi. 10.1016/j.febslet.2013.10.001

By:

Hoshi, Taisuke;
Tezuka, Tohru;
Yokoyama, Kazumasa;
Iemura, Shun-ichiro;
Natsume, Tohru;
Yamanashi, Yuji

Publication type:

Article

A Mutation Causes MuSK Reduced Sensitivity to Agrin and Congenital Myasthenia.

Published in:

PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053826

By:

Ammar, Asma Ben;
Soltanzadeh, Payam;
Bauché, Stéphanie;
Richard, Pascale;
Goillot, Evelyne;
Herbst, Ruth;
Gaudon, Karen;
Huzé, Caroline;
Schaeffer, Laurent;
Yamanashi, Yuji;
Higuchi, Osamu;
Taly, Antoine;
Koenig, Jeanine;
Leroy, Jean-Paul;
Hentati, Fayçal;
Najmabadi, Hossein;
Kahrizi, Kimia;
Ilkhani, Manouchehr;
Fardeau, Michel;
Eymard1, Bruno

Publication type:

Article

Characterization of disease-specific alterations in metabolites and effects of mesenchymal stromal cells on dystrophic muscles.

Published in:

Frontiers in Cell & Developmental Biology, 2024, p. 1, doi. 10.3389/fcell.2024.1363541

By:

Yuko Nitahara-Kasahara;
Posadas-Herrera, Guillermo;
Kunio Hirai;
Yuki Oda;
Noriko Snagu-Miyamoto;
Yuji Yamanashi;
Takashi Okada

Publication type:

Article

The roles of Dok family adapters in immunoreceptor signaling.

Published in:

Immunological Reviews, 2009, v. 232, n. 1, p. 273, doi. 10.1111/j.1600-065X.2009.00844.x

By:

Mashima, Ryuichi;
Hishida, Yukihiro;
Tezuka, Tohru;
Yamanashi, Yuji

Publication type:

Article

DOK1 and DOK2 regulate CD8 T cell signaling and memory formation without affecting tumor cell killing.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-66075-0

By:

Laletin, Vladimir;
Bernard, Pierre-Louis;
Montersino, Camille;
Yamanashi, Yuji;
Olive, Daniel;
Castellano, Rémy;
Guittard, Geoffrey;
Nunès, Jacques A.

Publication type:

Article

Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23134-8

By:

Wang, Qingbo S.;
Kelley, David R.;
Ulirsch, Jacob;
Kanai, Masahiro;
Sadhuka, Shuvom;
Cui, Ran;
Albors, Carlos;
Cheng, Nathan;
Okada, Yukinori;
The Biobank Japan Project;
Matsuda, Koichi;
Yamanashi, Yuji;
Furukawa, Yoichi;
Morisaki, Takayuki;
Murakami, Yoshinori;
Kamatani, Yoichiro;
Muto, Kaori;
Nagai, Akiko;
Obara, Wataru;
Yamaji, Ken

Publication type:

Article