Works matching DE "GENETIC pleiotropy"

Results: 689

COVID-19 and stroke MR study: data errors, timing gaps, statistical flaws.

Published in:

Virology Journal, 2025, v. 22, n. 1, p. 1, doi. 10.1186/s12985-025-02852-1

By:

Zhu, Xiaoyang;
He, Dan

Publication type:

Article

身体质量指数与妊娠期高血压综合征的双向孟德尔随机化研究.

Published in:

Bachu Medical Journal, 2025, v. 8, n. 2, p. 112, doi. 10.3969/j.issn.2096-6113,2025,02,019

By:

周安荔;
覃朝玲

Publication type:

Article

Assessing the causal association between smoking behavior and risk of gout using a Mendelian randomization study.

Published in:

Clinical Rheumatology, 2018, v. 37, n. 11, p. 3099, doi. 10.1007/s10067-018-4210-3

By:

Lee, Young Ho

Publication type:

Article

Coffee consumption and the risk of rheumatoid arthritis and systemic lupus erythematosus: a Mendelian randomization study.

Published in:

Clinical Rheumatology, 2018, v. 37, n. 10, p. 2875, doi. 10.1007/s10067-018-4278-9

By:

Bae, Sang-Cheol;
Lee, Young Ho

Publication type:

Article

Promoter recruitment of corepressors Sin3 and Cyc8 by activator proteins of the yeast Saccharomyces cerevisiae.

Published in:

Current Genetics, 2017, v. 63, n. 4, p. 739, doi. 10.1007/s00294-017-0677-8

By:

Kliewe, Felix;
Engelhardt, Maike;
Aref, Rasha;
Schüller, Hans-Joachim

Publication type:

Article

DasR is a pleiotropic regulator required for antibiotic production, pigment biosynthesis, and morphological development in Saccharopolyspora erythraea.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 23, p. 10215, doi. 10.1007/s00253-015-6892-7

By:

Liao, Cheng-Heng;
Xu, Ya;
Rigali, Sébastien;
Ye, Bang-Ce

Publication type:

Article

Pleiotropic Functions of Fibroblast Growth Factor Signaling in Embryonic Mammary Gland Development.

Published in:

Journal of Mammary Gland Biology & Neoplasia, 2013, v. 18, n. 2, p. 139, doi. 10.1007/s10911-013-9278-4

By:

Kim, Eun-Jung;
Jung, Han-Sung;
Lu, Pengfei

Publication type:

Article

The causal association between ankylosing spondylitis and endometrial cancer: a two-sample mendelian randomization study.

Published in:

Discover Oncology, 2025, v. 16, n. 1, p. 1, doi. 10.1007/s12672-025-02399-1

By:

Gu, Yanpin;
Shao, Yupei

Publication type:

Article

The association between vitamin D and Hashimoto’s thyroiditis.

Published in:

Medicine Science, 2021, v. 10, n. 4, p. 1446, doi. 10.5455/medscience.2021.08.249

By:

Guzelsagaltici, Cevdet;
Pamuk, Gulseren;
Cavdar, Umit;
Ihtiyar, Alperen;
Narin, Figen;
Pamuk, Baris Onder

Publication type:

Article

Identification of shared genetic etiology of cardiovascular and cerebrovascular diseases through common cardiometabolic risk factors.

Published in:

Communications Biology, 2024, v. 7, n. 1, p. 1, doi. 10.1038/s42003-024-07417-6

By:

Ding, Kexin;
Qin, Xueying;
Wang, Huairong;
Wang, Kun;
Kang, Xiaoying;
Yu, Yao;
Liu, Yang;
Gong, Haiying;
Wu, Tao;
Chen, Dafang;
Hu, Yonghua;
Wang, Tao;
Wu, Yiqun

Publication type:

Article

Complex pleiotropy characterizes the pollen hoarding syndrome in honey bees ( Apis mellifera L.).

Published in:

Behavioral Ecology & Sociobiology, 2012, v. 66, n. 11, p. 1459, doi. 10.1007/s00265-012-1400-x

By:

Page, Robert;
Fondrk, M.;
Rueppell, Olav

Publication type:

Article

Genome-Wide Pleiotropy Study Identifies Association of PDGFB with Age-Related Macular Degeneration and COVID-19 Infection Outcomes.

Published in:

Journal of Clinical Medicine, 2023, v. 12, n. 1, p. 109, doi. 10.3390/jcm12010109

By:

Chung, Jaeyoon;
Vig, Viha;
Sun, Xinyu;
Han, Xudong;
O'Connor, George T.;
Chen, Xuejing;
DeAngelis, Margaret M.;
Farrer, Lindsay A.;
Subramanian, Manju L.

Publication type:

Article

Estimates of epistatic and pleiotropic effects of casein alpha s1 (CSN1S1) and thyroglobulin (TG) genetic markers on beef heifer performance traits enhanced by selection.

Published in:

Journal of Animal Science, 2016, v. 94, n. 3, p. 920, doi. 10.2527/jas.2015-9860

By:

Tait, R. G.;
Cushman, R. A.;
McNee, A. K.;
Casas, E.;
Smith, T. P. L.;
Freetly, H. C.;
Bennett, G. L.

Publication type:

Article

Genome-wide association studies of female reproduction in tropically adapted beef cattle.

Published in:

Journal of Animal Science, 2012, v. 90, n. 5, p. 1398, doi. 10.2527/jas.2011-4410

By:

Hawken, R. J.;
Zhang, Y. D.;
Fortes, M. R. S.;
Collis, E.;
Barris, W. C.;
Corbet, N. J.;
Williams, P. J.;
Fordyce, G.;
Holroyd, R. G.;
J. R. W. Walkley;
Barendse, W.;
Johnston, D. J.;
Prayaga, K. C.;
Tier, B.;
Reverter, A.;
Lehnert, S. A.

Publication type:

Article

APOE Genotype and Cognitive Change in Young, Middle-Aged, and Older Adults Living in the Community.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2014, v. 69, n. 4, p. 379, doi. 10.1093/gerona/glt103

By:

Bunce, David;
Bielak, Allison A. M.;
Anstey, Kaarin J;
Cherbuin, Nicolas;
Batterham, Philip J.;
Easteal, Simon

Publication type:

Article

Pleiotropy and Life History Evolution in Drosophila melanogaster: Uncoupling Life Span and Early Fecundity.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 5, p. 546, doi. 10.1093/gerona/gls226

By:

Khazaeli, Aziz A.;
Curtsinger, James W.

Publication type:

Article

Causal association between body mass index and autoimmune thyroiditis: evidence from Mendelian randomization.

Published in:

European Journal of Medical Research, 2023, v. 28, n. 1, p. 1, doi. 10.1186/s40001-023-01480-1

By:

Huo, Jinlong;
Xu, Yaxuan;
Yu, Jie;
Guo, Youming;
Hu, Xiaochi;
Ou, Dong;
Qu, Rui;
Zhao, Lijin

Publication type:

Article

Coat colour in mouse populations selected for weight gain: support for hitchhiking, not pleiotropy.

Published in:

Genetics Research, 2013, v. 95, n. 1, p. 4, doi. 10.1017/S0016672312000778

By:

HEDRICK, PHILIP W.

Publication type:

Article

The fitness effects of a pale mutant in the aposematic seed bug Lygaeus simulans indicate pleiotropy between warning coloration and life history.

Published in:

Ecology & Evolution (20457758), 2018, v. 8, n. 24, p. 12855, doi. 10.1002/ece3.4723

By:

Balfour, Vicki L.;
Aumont, Cédric;
Dougherty, Liam R.;
Shuker, David M.

Publication type:

Article

Morphological and biological characterization of a light‐colored mutant in the multicolored Asian lady beetle, Harmonia axyridis.

Published in:

Ecology & Evolution (20457758), 2018, v. 8, n. 20, p. 9975, doi. 10.1002/ece3.4379

By:

Sun, Yuan‐xing;
Hao, Ya‐nan;
Yan, Yu;
Zhang, Yi;
Feng, Yi;
Liu, Tong‐xian

Publication type:

Article

Assessing the utility of metabarcoding for diet analyses of the omnivorous wild pig ( Sus scrofa).

Published in:

Ecology & Evolution (20457758), 2018, v. 8, n. 1, p. 185, doi. 10.1002/ece3.3638

By:

Robeson, II, Michael S.;
Khanipov, Kamil;
Golovko, George;
Wisely, Samantha M.;
White, Michael D.;
Bodenchuck, Michael;
Smyser, Timothy J.;
Fofanov, Yuriy;
Fierer, Noah;
Piaggio, Antoinette J.

Publication type:

Article

Gillespie eco-evolutionary models ( GEMs) reveal the role of heritable trait variation in eco-evolutionary dynamics.

Published in:

Ecology & Evolution (20457758), 2016, v. 6, n. 4, p. 935, doi. 10.1002/ece3.1959

By:

DeLong, John P.;
Gibert, Jean P.

Publication type:

Article

The genetics of phenotypic plasticity. XIII. Interactions with developmental instability.

Published in:

Ecology & Evolution (20457758), 2014, v. 4, n. 8, p. 1347, doi. 10.1002/ece3.1039

By:

Scheiner, Samuel M.

Publication type:

Article

Functional Phylogenetics Reveals Contributions of Pleiotropic Peptide Action to Ligand-Receptor Coevolution.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep06800

By:

Hongbo Jiang;
Zhaojun Wei;
Nachman, Ronald J.;
Adams, Michael E.;
Yoonseong Park

Publication type:

Article

Gibberellin deficiency pleiotropically induces culm bending in sorghum: an insight into sorghum semi-dwarf breeding.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep05287

By:

Ordonio, Reynante L.;
Ito, Yusuke;
Hatakeyama, Asako;
Ohmae-Shinohara, Kozue;
Kasuga, Shigemitsu;
Tokunaga, Tsuyoshi;
Mizuno, Hiroshi;
Kitano, Hidemi;
Matsuoka, Makoto;
Sazuka, Takashi

Publication type:

Article

Considerations for designing chemical screening strategies in plant biology.

Published in:

Frontiers in Plant Science, 2015, p. 1, doi. 10.3389/fpls.2015.00131

By:

Serrano, Mario;
Kombrink, Erich;
Meesters, Christian

Publication type:

Article

The Association of CYP19A1 Variation with Circulating Estradiol and Aromatase Inhibitor Outcome: Can CYP19A1 Variants Be Used to Predict Treatment Efficacy?

Published in:

Frontiers in Pharmacology, 2017, v. 8, p. 1, doi. 10.3389/fphar.2017.00218

By:

Glubb, Dylan M.;
O'Mara, Tracy A.;
Shamsani, Jannah;
Spurdle, Amanda B.

Publication type:

Article

Primary biliary cirrhosis and psoriasis: a two-sample Mendelian randomization study.

Published in:

Frontiers in Immunology, 2024, p. 1, doi. 10.3389/fimmu.2023.1264554

By:

Diqian Zhao;
Qinyu Zhao;
Fangwei Xu;
Fang Zhang;
Wenzhe Bai

Publication type:

Article

A rare case of myelodysplastic syndrome with refractory thrombocytopenia.

Published in:

Hematology Reports, 2015, v. 7, n. 3, p. 60, doi. 10.4081/hr.2015.5897

By:

Jehangir, Waqas;
Singh, Shilpi;
Arshed, Sabrina;
Sen, Shuvendu;
Yousif, Abdalla;
Webb, John

Publication type:

Article

Is Hearing Impairment Causally Associated With Falls? Evidence From a Two-Sample Mendelian Randomization Study.

Published in:

Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.876165

By:

Wang, Jun;
Liu, Dan;
Tian, E.;
Guo, Zhao-Qi;
Chen, Jing-Yu;
Kong, Wei-Jia;
Zhang, Su-Lin

Publication type:

Article

Paroxysmal Movement Disorders.

Published in:

Frontiers in Neurology, 2021, v. 12, p. 1, doi. 10.3389/fneur.2021.659064

By:

Harvey, Susan;
King, Mary D.;
Gorman, Kathleen M.

Publication type:

Article

Developmental constraint through negative pleiotropy in the zygomatic arch.

Published in:

EvoDevo, 2018, v. 9, p. 1, doi. 10.1186/s13227-018-0092-3

By:

Percival, Christopher J.;
Green, Rebecca;
Roseman, Charles C.;
Gatti, Daniel M.;
Morgan, Judith L.;
Murray, Stephen A.;
Donahue, Leah Rae;
Mayeux, Jessica M.;
Pollard, K. Michael;
Hua, Kunjie;
Pomp, Daniel;
Marcucio, Ralph;
Hallgrímsson, Benedikt

Publication type:

Article

Transcription factor NF-YA promotes a malignant phenotype by upregulating fatty acid synthase expression.

Published in:

Molecular Medicine Reports, 2016, v. 14, n. 6, p. 5007, doi. 10.3892/mmr.2016.5897

By:

JING GUO;
LING MIN KONG;
AI FEN PENG;
XIN HUA LONG;
YANG ZHOU;
YONG SHU

Publication type:

Article

REDUCE, REUSE, AND RECYCLE: DEVELOPMENTAL EVOLUTION OF TRAIT DIVERSIFICATION.

Published in:

American Journal of Botany, 2011, v. 98, n. 3, p. 397, doi. 10.3732/ajb.1000279

By:

PRESTON, JILL C.;
HILEMAN, LENA C.;
CUBAS, PILAR

Publication type:

Article

MGRN1-dependent pigment-type switching requires its ubiquitination activity but not its interaction with TSG101 or NEDD4.

Published in:

Pigment Cell & Melanoma Research, 2013, v. 26, n. 2, p. 263, doi. 10.1111/pcmr.12059

By:

Gunn, Teresa M.;
Silvius, Derek;
Bagher, Pooneh;
Sun, Kaihua;
Walker, Katherine K.

Publication type:

Article

The MAPT p.P301L mutation presents as a rare early-onset corticobasal syndrome: A case report.

Published in:

Neurology Asia, 2023, v. 28, n. 1, p. 211, doi. 10.54029/2023ejf

By:

Cheng-Hsuan Li;
Ni-Chung Lee;
Kun-Ju Lin;
Ing-Tsung Hsiao;
Yi-Hsin Weng;
Chin-Hsien Lin

Publication type:

Article

The MAPT p.P301L mutation presents as a rare early-onset corticobasal syndrome: A case report.

Published in:

Neurology Asia, 2023, v. 28, n. 1, p. 211, doi. 10.54029/2023ejf

By:

Cheng-Hsuan Li;
Ni-Chung Lee;
Kun-Ju Lin;
Ing-Tsung Hsiao;
Yi-Hsin Weng;
Chin-Hsien Lin

Publication type:

Article

What is evolutionary novelty? Process versus character based definitions.

Published in:

Journal of Experimental Zoology Part B: Molecular & Developmental Evolution, 2013, v. 320, n. 6, p. 345, doi. 10.1002/jez.b.22508

By:

Peterson, Tim;
Müller, Gerd B.

Publication type:

Article

The Oscillopathic Nature of Language Deficits in Autism: From Genes to Language Evolution.

Published in:

Frontiers in Human Neuroscience, 2016, p. 1, doi. 10.3389/fnhum.2016.00120

By:

Benítez-Burraco, Antonio;
Murphy, Elliot;
Sam McLeod Doesburg;
Jochaut, Delphine

Publication type:

Article

Two-sample Mendelian randomization analysis of the causal relationship between lipid metabolism/fatty acid metabolism and pre-eclampsia.

Published in:

Ginekologia Polska, 2025, v. 96, n. 4, p. 256, doi. 10.5603/gpl.101256

By:

Dan Yang;
Jin Chen;
Xiaoyin Wang;
Lin Zhuang;
Hongjun Feng;
Xue Liao;
Ting Mo

Publication type:

Article

Protease-Mediated Suppression of DRG Neuron Excitability by Commensal Bacteria.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 48, p. 11758, doi. 10.1523/JNEUROSCI.1672-17.2017

By:

Sessenwein, Jessica L.;
Baker, Corey C.;
Pradhananga, Sabindra;
Maitland, Megan E.;
Petrof, Elaine O.;
Allen-Vercoe, Emma;
Noordhof, Curtis;
Reed, David E.;
Vanner, Stephen J.;
Lomax, Alan E.

Publication type:

Article

The roles of HOXD10 in the development and progression of head and neck squamous cell carcinoma (HNSCC).

Published in:

British Journal of Cancer, 2014, v. 111, n. 4, p. 807, doi. 10.1038/bjc.2014.372

By:

Hakami, F;
Darda, L;
Stafford, P;
Woll, P;
Lambert, D W;
Hunter, K D

Publication type:

Article

The TERT variant rs2736100 is associated with colorectal cancer risk.

Published in:

British Journal of Cancer, 2012, v. 107, n. 6, p. 1001, doi. 10.1038/bjc.2012.329

By:

Kinnersley, B;
Migliorini, G;
Broderick, P;
Whiffin, N;
Dobbins, S E;
Casey, G;
Hopper, J;
Sieber, O;
Lipton, L;
Kerr, D J;
Dunlop, M G;
Tomlinson, I PM;
Houlston, R S

Publication type:

Article

RARS2 mutations in a sibship with infantile spasms.

Published in:

Epilepsia (Series 4), 2016, v. 57, n. 5, p. e97, doi. 10.1111/epi.13358

By:

Ngoh, Adeline;
Bras, Jose;
Guerreiro, Rita;
Meyer, Esther;
McTague, Amy;
Dawson, Eleanor;
Mankad, Kshitij;
Gunny, Roxana;
Clayton, Peter;
Mills, Philippa B.;
Thornton, Rachel;
Lai, Ming;
Forsyth, Robert;
Kurian, Manju A.

Publication type:

Article

Stress-responsive pathways and small RNA changes distinguish variable developmental phenotypes caused by MSH1 loss.

Published in:

BMC Plant Biology, 2017, v. 17, p. 1, doi. 10.1186/s12870-017-0996-4

By:

Shao, Mon-Ray;
Raju, Sunil Kumar Kenchanmane;
Laurie, John D.;
Sanchez, Robersy;
Mackenzie, Sally A.

Publication type:

Article

Pleiotropic genetic association analysis with multiple phenotypes using multivariate response best-subset selection.

Published in:

BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09820-5

By:

Guo, Hongping;
Li, Tong;
Wang, Zixuan

Publication type:

Article

Evolution of an adaptive behavior and its sensory receptors promotes eye regression in blind cavefish: response to Borowsky (2013).

Published in:

BMC Biology, 2013, v. 11, n. 1, p. 1, doi. 10.1186/1741-7007-11-82

By:

Yoshizawa, Masato;
O'Quin, Kelly E.;
Jeffery, William R.

Publication type:

Article

Intra-population variability in the drought response of a beech (Fagus sylvatica L.) population in the southwest of Europe.

Published in:

Tree Physiology, 2017, v. 37, n. 7, p. 938, doi. 10.1093/treephys/tpx058

By:

Aranda, Ismael;
Bahamonde, Hector A.;
Sánchez-Gómez, David

Publication type:

Article

Unintended consequences: high phosphinothricin acetyltransferase activity related to reduced fitness in barley.

Published in:

In Vitro Cellular & Developmental Biology Plant, 2013, v. 49, n. 3, p. 240, doi. 10.1007/s11627-013-9506-z

By:

Brown, Ryan;
Raboy, Victor;
Bregitzer, Phil

Publication type:

Article

Pleiotropic effects of angiopoietin-2 deficiency do not protect mice against endotoxin-induced acute kidney injury.

Published in:

Nephrology Dialysis Transplantation, 2013, v. 28, n. 3, p. 567, doi. 10.1093/ndt/gfs336

By:

Kurniati, Neng F.;
van Meurs, Matijs;
vom Hagen, Franziska;
Jongman, Rianne M.;
Moser, Jill;
Zwiers, Peter J.;
Struys, Michel M.R.F.;
Westra, Johanna;
Zijlstra, Jan G.;
Hammes, Hans-Peter;
Molema, Grietje;
Heeringa, Peter

Publication type:

Article