Works matching DE "CATALYTIC RNA"

Results: 1086

Opening new frontiers with catalytic nucleic acids in miRNA inhibition.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1604711

By:

Patutina, Olga;
Miroshnichenko, Svetlana;
Chiglintseva, Daria;
Zenkova, Marina

Publication type:

Article

Fusing Allosteric Ribozymes with CRISPR‐Cas12a for Efficient Diagnostics of Small Molecule Targets.

Published in:

Small Methods, 2025, v. 9, n. 6, p. 1, doi. 10.1002/smtd.202401236

By:

Guo, Lichuan;
Zhang, Shu;
Du, Xinyu;
Zhou, Mo;
Gu, Hongzhou

Publication type:

Article

RNA triphosphatase-mediated mRNA capping is essential for maintaining transcript homeostasis and the survival of Toxoplasma gondii.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-59867-z

By:

Aswale, Kalyani R.;
Kashyap, Poonam;
Deshmukh, Abhijit S.

Publication type:

Article

An Engineered RNase P Ribozyme Effectively Reduces Human Coronavirus 229E Gene Expression and Growth in Human Cells.

Published in:

Zoonotic Diseases (2813-0227), 2025, v. 5, n. 2, p. 12, doi. 10.3390/zoonoticdis5020012

By:

Liu, Yujun;
Yan, Bin;
Gong, Hao;
Liu, Fenyong

Publication type:

Article

Epitranscriptomics Regulation of CD70, CD80, and TIGIT in Cancer Immunity.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5772, doi. 10.3390/ijms26125772

By:

Rigopoulos, Christos Panagiotis;
Gkoris, Marios;
Georgakopoulos-Soares, Ilias;
Boulalas, Ioannis;
Zaravinos, Apostolos

Publication type:

Article

Hammerhead Ribozymes: Structural Insights, Catalytic Mechanisms, and Cutting-Edge Applications in Synthetic Biology.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5624, doi. 10.3390/ijms26125624

By:

Wang, Liangliang;
Liu, Yan;
Xian, Xuemin;
Zhang, Haitao

Publication type:

Article

mRNA Secondary Structures Fold Sequentially But Exchange Rapidly In Vivo.

Published in:

PLoS Biology, 2010, v. 8, n. 2, p. 1, doi. 10.1371/journal.pbio.1000307

By:

Mahen, Elisabeth M.;
Watson, Peter Y.;
Cottrell, Joseph W.;
Fedor, Martha J.

Publication type:

Article

An Endoribonuclease Functionally Linked to Perinuclear mRNP Quality Control Associates with the Nuclear Pore Complexes.

Published in:

PLoS Biology, 2009, v. 7, n. 1, p. e1000008, doi. 10.1371/journal.pbio.1000008

By:

Skrunžný, Michal;
Schneider, Claudia;
Rácz, Attila;
Weng, Julan;
Tollervey, David;
Hurt, Ed

Publication type:

Article

Capturing Hammerhead Ribozyme Structures in Action by Modulating General Base Catalysis.

Published in:

PLoS Biology, 2008, v. 6, n. 9, p. e234, doi. 10.1371/journal.pbio.0060234

By:

Young-In Chi;
Martick, Monika;
Lares, Monica;
Kim, Rosalind;
Scott, William G.;
Sung-Hou Kim

Publication type:

Article

Slowing Down a Hammerhead Ribozyme Allows Glimpses of It in Action.

Published in:

PLoS Biology, 2008, v. 6, n. 9, p. e244, doi. 10.1371/journal.pbio.0060244

By:

Meadows, Robin

Publication type:

Article

The Threat of Instability: Neurodegeneration Predicted by Protein Destabilization and Aggregation Propensity.

Published in:

PLoS Biology, 2008, v. 6, n. 7, p. e193, doi. 10.1371/journal.pbio.0060193

By:

Meiering, Elizabeth M.

Publication type:

Article

Man versus Machine versus Ribozyme.

Published in:

PLoS Biology, 2008, v. 6, n. 5, p. e132, doi. 10.1371/journal.pbio.0060132

By:

Ellington, Andrew D.

Publication type:

Article

Darwinian Evolution on a Chip.

Published in:

PLoS Biology, 2008, v. 6, n. 4, p. e85, doi. 10.1371/journal.pbio.0060085

By:

Paegel, Brian M.;
Joyce, Gerald F.

Publication type:

Article

The Ol' Switcheroo Shows How an RNA Enzyme Splices Itself.

Published in:: PLoS Biology, 2005, v. 3, n. 9, p. 1512, doi. 10.1371/journal.pbio.0030310
Publication type:: Article

Functional Identification of Catalytic Metal Ion Binding Sites within RNA.

Published in:

PLoS Biology, 2005, v. 3, n. 9, p. 1536, doi. 10.1371/journal.pbio.0030277

By:

Hougland, James L.;
Kravchuk, Alexander V.;
Herschlag, Daniel;
Piccirilli, Joseph A.

Publication type:

Article

RNAi Therapeutics: How Likely, How Soon?

Published in:

PLoS Biology, 2004, v. 2, n. 1, p. 1, doi. 10.1371/journal.pbio.0020028

By:

Robinson, Richard

Publication type:

Article

CircRNAs and their regulatory roles in cancers.

Published in:

Molecular Medicine, 2021, v. 27, n. 1, p. 1, doi. 10.1186/s10020-021-00359-3

By:

Tao, Mei;
Zheng, Ming;
Xu, Yanhua;
Ma, Shuo;
Zhang, Weiwei;
Ju, Shaoqing

Publication type:

Article

Splicing and evolution of an unusually small group I intron.

Published in:

Current Genetics, 2008, v. 54, n. 4, p. 213, doi. 10.1007/s00294-008-0213-y

By:

Harris, Lorena;
Rogers, Scott O.

Publication type:

Article

Novel and tightly regulated resorcinol and cumate-inducible expression systems for Streptomyces and other actinobacteria.

Published in:

Applied Microbiology & Biotechnology, 2014, v. 98, n. 20, p. 8641, doi. 10.1007/s00253-014-5918-x

By:

Horbal, Liliya;
Fedorenko, Victor;
Luzhetskyy, Andriy

Publication type:

Article

Physicochemical Characterization of the Catalytic Unit of Hammerhead Ribozyme and Its Relationship with the Catalytic Activity.

Published in:

Biophysica, 2022, v. 2, n. 3, p. 221, doi. 10.3390/biophysica2030022

By:

Tanaka, Yoshiyuki;
Yamanaka, Daichi;
Morioka, Saori;
Yamaguchi, Taishi;
Morikawa, Masayuki;
Kodama, Takashi S.;
Sychrovský, Vladimír;
Kojima, Chojiro;
Hattori, Yoshikazu

Publication type:

Article

Nonenzymatic Template-Directed Primer Extension Using 2′-3′ Cyclic Nucleotides Under Wet-Dry Cycles.

Published in:

Origins of Life & Evolution of the Biosphere, 2023, v. 53, n. 1/2, p. 43, doi. 10.1007/s11084-023-09636-z

By:

Dagar, Shikha;
Sarkar, Susovan;
Rajamani, Sudha

Publication type:

Article

Quadruplex World.

Published in:

Origins of Life & Evolution of the Biosphere, 2021, v. 51, n. 3, p. 273, doi. 10.1007/s11084-021-09611-6

By:

Kankia, Besik

Publication type:

Article

In vitro selection of novel ligase ribozymes.

Published in:

1996

By:

Hager, Alicia;
Szostak, Jack

Publication type:

Abstract

The role of catalytic RNA in the origin and early evolution of life on earth.

Published in:

1996

By:

Joyce, Gerald

Publication type:

Abstract

The search for missing links between self-replicating nucleic ACIDs and the RNA world.

Published in:

Origins of Life & Evolution of the Biosphere, 1995, v. 25, n. 6, p. 515, doi. 10.1007/BF01582021

By:

James, Kenneth;
Ellington, Andrew

Publication type:

Article

The dynamics of prebiotic take-off: the transfer of functional RNA communities from mineral surfaces to vesicles.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07841-2

By:

Vörös, Dániel;
Czárán, Tamás;
Szilágyi, András;
Könnyű, Balázs

Publication type:

Article

A hammerhead ribozyme selects mechanically stable conformations for catalysis against viral RNA.

Published in:

Communications Biology, 2025, v. 8, n. 1, p. 1, doi. 10.1038/s42003-025-07600-3

By:

Lu, Man;
Cao, Zhiqiang;
Xiong, Luoan;
Deng, Hongying;
Ma, Kangkang;
Liu, Ning;
Qin, Yanding;
Chen, Shen-Bo;
Chen, Jun-Hu;
Li, Yao;
Liu, Yijin;
Yu, Zhongbo

Publication type:

Article

Characterization of a novel Stenotrophomonas isolate with high keratinase activity and purification of the enzyme.

Published in:

Journal of Industrial Microbiology & Biotechnology, 2009, v. 36, n. 2, p. 181, doi. 10.1007/s10295-008-0469-8

By:

Zhang-Jun Cao;
Qi Zhang;
Dong-Kai Wei;
Li Chen;
Jing Wang;
Xing-Qun Zhang;
Mei-Hua Zhou

Publication type:

Article

Riboswitch identification using Ligase-Assisted Selection for the Enrichment of Responsive Ribozymes (LigASERR).

Published in:

Synthetic Biology (23977000), 2019, v. 4, n. 1, p. N.PAG, doi. 10.1093/synbio/ysz019

By:

Haines, Matthew C;
Storch, Marko;
Oyarzún, Diego A;
Stan, Guy-Bart;
Baldwin, Geoff S

Publication type:

Article

Preclinical Anticancer Activity of DNA-based Cleavage Molecules.

Published in:

Drug Development & Industrial Pharmacy, 2006, v. 32, n. 1, p. 1, doi. 10.1080/03639040500387872

By:

Dass, Crispin R.

Publication type:

Article

Lee Raleigh Shugart.

Published in:

Ecotoxicology, 2021, v. 30, n. 10, p. 1949, doi. 10.1007/s10646-021-02501-7

By:

Theodorakis, Chris;
Bickham, John;
Bartell, Steve

Publication type:

Article

rAAV-Mediated Cochlear Gene Therapy: Prospects and Challenges for Clinical Application.

Published in:

Journal of Clinical Medicine, 2020, v. 9, n. 2, p. 589, doi. 10.3390/jcm9020589

By:

Blanc, Fabian;
Mondain, Michel;
Bemelmans, Alexis-Pierre;
Affortit, Corentin;
Puel, Jean-Luc;
Wang, Jing

Publication type:

Article

Maternal nutrition effects on lipogenic enzyme messenger RNA in adipose tissue of suckling calves.

Published in:

Journal of Animal Science, 2006, v. 84, p. 70

By:

Murrieta, C. M.;
Lake, S. L.;
Scholljegerdes, E. J.;
Hess, B. W.;
Rule, D. C.

Publication type:

Article

Modelling Functional Shifts in Two-Species Hypercycles.

Published in:

Mathematics (2227-7390), 2021, v. 9, n. 15, p. 1809, doi. 10.3390/math9151809

By:

Bassols, Bernat;
Fontich, Ernest;
Oro, Daniel;
Alonso, David;
Sardanyés, Josep

Publication type:

Article

The Proto-Ribosome: An Ancient Nano-machine for Peptide Bond Formation.

Published in:

Israel Journal of Chemistry, 2010, v. 50, n. 1, p. 29, doi. 10.1002/ijch.201000012

By:

Davidovich, Chen;
Belousoff, Matthew;
Wekselman, Itai;
Shapira, Tal;
Krupkin, Miri;
Zimmerman, Ella;
Bashan, Anat;
Yonath, Ada

Publication type:

Article

Stochastic parabolic growth promotes coexistence and a relaxed error threshold in RNA-like replicator populations.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.93208

By:

Paczkó, Mátyás;
Szathmáry, Eörs;
Szilágyi, András

Publication type:

Article

Emergence of catalytic function in prebiotic information-coding polymers.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.91397

By:

Tkachenko, Alexei V.;
Maslov, Sergei

Publication type:

Article

The catalytic mechanism of the RNA methyltransferase METTL3.

Published in:

eLife, 2024, p. 1, doi. 10.7554/eLife.92537

By:

Corbeski, Ivan;
Andrés Vargas-Rosales, Pablo;
Bedi, Rajiv Kumar;
Jiahua Deng;
Coelho, Dylan;
Braud, Emmanuelle;
Iannazzo, Laura;
Yaozong Li;
Danzhi Huang;
Ethève-Quelquejeu, Mélanie;
Qiang Cui;
Caflisch, Amedeo

Publication type:

Article

Ribozyme activity modulates the physical properties of RNA--peptide coacervates.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.83543

By:

Le Vay, Kristian Kyle;
Salibi, Elia;
Ghosh, Basusree;
Tang, T. Y. Dora;
Mutschler, Hannes

Publication type:

Article

Virus-associated ribozymes and nano carriers against COVID-19.

Published in:

Artificial Cells, Nanomedicine & Biotechnology, 2021, v. 49, n. 1, p. 204, doi. 10.1080/21691401.2021.1890103

By:

Dönmüş, Beyza;
Ünal, Sinan;
Kirmizitaş, Fatma Ceren;
Türkoğlu Laçin, Nelisa

Publication type:

Article

Dual sgRNA-directed gene knockout using CRISPR/Cas9 technology in Caenorhabditis elegans.

Published in:

Scientific Reports, 2014, p. 7581, doi. 10.1038/srep07581

By:

Chen, Xiangyang;
Xu, Fei;
Zhu, Chengming;
Ji, Jiaojiao;
Zhou, Xufei;
Feng, Xuezhu;
Guang, Shouhong

Publication type:

Article

Non-integrating gamma-retroviral vectors as a versatile tool for transient zinc-finger nuclease delivery.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep04656

By:

Bobis-Wozowicz, Sylwia;
Galla, Melanie;
Alzubi, Jamal;
Kuehle, Johannes;
Baum, Christopher;
Schambach, Axel;
Cathomen, Toni

Publication type:

Article

Group II intron splicing factors in plant mitochondria.

Published in:

Frontiers in Plant Science, 2014, v. 5, p. 1, doi. 10.3389/fpls.2014.00035

By:

Brown, Gregory G.;
Francs-Small, Catherine Colasdes;
Ostersetzer-Biran, Oren

Publication type:

Article

Genetic recombination in plant-infecting messenger-sense RNA viruses: overview and research perspectives.

Published in:

Frontiers in Plant Science, 2013, v. 4, p. 1, doi. 10.3389/fpls.2013.00068

By:

Bujarski, Jozef J.;
Zerbini, F. Murilo;
Pita, Justin

Publication type:

Article

Adapting CRISPR/Cas9 System for Targeting Mitochondrial Genome.

Published in:

Frontiers in Genetics, 2021, v. 11, p. N.PAG, doi. 10.3389/fgene.2021.627050

By:

Hussain, Syed-Rehan A.;
Yalvac, Mehmet E.;
Khoo, Benedict;
Eckardt, Sigrid;
McLaughlin, K. John

Publication type:

Article

Machine Learning Based Computational Gene Selection Models: A Survey, Performance Evaluation, Open Issues, and Future Research Directions.

Published in:

Frontiers in Genetics, 2020, v. 11, p. N.PAG, doi. 10.3389/fgene.2020.603808

By:

Mahendran, Nivedhitha;
Durai Raj Vincent, P. M.;
Srinivasan, Kathiravan;
Chang, Chuan-Yu

Publication type:

Article

Characterization of nuclease-resistant ribozymes directed against hepatitis B virus RNA*.

Published in:

Journal of Viral Hepatitis, 2002, v. 9, n. 6, p. 411, doi. 10.1046/j.1365-2893.2002.00383.x

By:

Morrissey, D. V.;
Lee, P. A.;
Johnson, D. A.;
Overly, S. L.;
McSwiggen, J. A.;
Beigelman, L.;
Mokler, V. R.;
Maloney, L.;
Vargeese, C.;
Bowman, K.;
O'Brien, J. T.;
Shaffer, C. S.;
Conrad, A.;
Schmid, P.;
Morrey, J. D.;
Macejak, D. G.;
Pavco, P. A.;
Blatt, L. M.

Publication type:

Article

Enhanced antiviral effect in cell culture of type 1 interferon and ribozymes targeting HCV RNA.

Published in:

Journal of Viral Hepatitis, 2001, v. 8, n. 6, p. 400, doi. 10.1046/j.1365-2893.2001.00321.x

By:

Macejak, D. G.;
Jensen, K. L.;
Pavco, P. A.;
Phipps, K. M.;
Heinz, B. A.;
Colacino, J. M.;
Blatt, L. M.

Publication type:

Article

Ocular Surface Expression of SARS-CoV-2 Receptors.

Published in:

2020

By:

Leonardi, Andrea;
Rosani, Umberto;
Brun, Paola

Publication type:

journal article

Determinants of selectivity in the dicing mechanism.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53322-1

By:

Le, Thi Nhu-Y;
Le, Cong Truc;
Nguyen, Tuan Anh

Publication type:

Article