Works matching DE "LIGAND-gated ion channels"

Results: 311

Lighting Up the Plasma Membrane: Development and Applications of Fluorescent Ligands for Transmembrane Proteins.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 34, p. 8605, doi. 10.1002/chem.202100296

By:

Borgarelli, Carlotta;
Klingl, Yvonne E.;
Escamilla‐Ayala, Abril;
Munck, Sebastian;
Van Den Bosch, Ludo;
De Borggraeve, Wim M.;
Ismalaj, Ermal

Publication type:

Article

Transient receptor potential vanilloid 1 (TRPV1)‐independent actions of capsaicin on cellular excitability and ion transport.

Published in:

Medicinal Research Reviews, 2023, v. 43, n. 4, p. 1038, doi. 10.1002/med.21945

By:

Oz, Murat;
Lorke, Dietrich E.;
Howarth, Frank C.

Publication type:

Article

Recent advances with 5‐HT3 modulators for neuropsychiatric and gastrointestinal disorders.

Published in:

Medicinal Research Reviews, 2020, v. 40, n. 5, p. 1593, doi. 10.1002/med.21666

By:

Juza, Radomir;
Vlcek, Premysl;
Mezeiova, Eva;
Musilek, Kamil;
Soukup, Ondrej;
Korabecny, Jan

Publication type:

Article

Nicotine as a female reproductive toxicant—A review.

Published in:

Journal of Applied Toxicology, 2025, v. 45, n. 4, p. 534, doi. 10.1002/jat.4702

By:

Bhardwaj, Jitender Kumar;
Siwach, Anshu;
Sachdeva, Som Nath

Publication type:

Article

GABAA receptors as targets for anaesthetics and analgesics and promising candidates to help treat coronavirus infections: A mini‐review.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2022, v. 131, n. 6, p. 443, doi. 10.1111/bcpt.13798

By:

Luo, Yujia;
Balle, Thomas

Publication type:

Article

Channels of Evolution: Unveiling Evolutionary Patterns in Diatom Ca 2+ Signalling.

Published in:

Plants (2223-7747), 2024, v. 13, n. 9, p. 1207, doi. 10.3390/plants13091207

By:

Murphy, Eleanor A.;
Kleiner, Friedrich H.;
Helliwell, Katherine E.;
Wheeler, Glen L.

Publication type:

Article

TPC1-Type Channels in Physcomitrium patens : Interaction between EF-Hands and Ca 2+.

Published in:

Plants (2223-7747), 2022, v. 11, n. 24, p. 3527, doi. 10.3390/plants11243527

By:

Mérida-Quesada, Franko;
Vergara-Valladares, Fernando;
Rubio-Meléndez, María Eugenia;
Hernández-Rojas, Naomí;
González-González, Angélica;
Michard, Erwan;
Navarro-Retamal, Carlos;
Dreyer, Ingo

Publication type:

Article

Haloperidol, a typical antipsychotic, inhibits 5-HT3 receptor-mediated currents in NCB-20 cells: a whole-cell patch-clamp study.

Published in:

Korean Journal of Physiology & Pharmacology, 2025, v. 29, n. 3, p. 349, doi. 10.4196/kjpp.24.320

By:

Yong Soo Park;
Gyu Min Kim;
Ho Jun Sung;
Ju Yeong Yu;
Ki-Wug Sung

Publication type:

Article

Combined Neurotoxic Effects of Commercial Formulations of Pyrethroid (Deltamethrin) and Neonicotinoid (Imidacloprid) Pesticides on Adult Zebrafish (Danio rerio): Behavioral, Molecular, and Histopathological Analysis.

Published in:

Life (2075-1729), 2025, v. 15, n. 4, p. 538, doi. 10.3390/life15040538

By:

Petrovici, Adriana;
Savuța, Gheorghe;
Lucini, Carla;
Robea, Madalina-Andreea;
Solcan, Carmen

Publication type:

Article

Editorial: Celebrating 40 Years of the Chilean Society of Pharmacology.

Published in:

2020

By:

Yévenes, Gonzalo E.;
Bravo, Javier A.;
Díaz-Araya, Guillermo;
Sotomayor-Zárate, Ramón;
Fiedler, Jenny L.;
Reyes-Parada, Miguel;
Fuentealba, Jorge

Publication type:

Editorial

Demystifying the Molecular Basis of Pyrazoloquinolinones Recognition at the Extracellular α1+/β3- Interface of the GABAA Receptor by Molecular Modeling.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.561834

By:

Singh, Natesh;
Villoutreix, Bruno O.

Publication type:

Article

Inhibition of the Glycine Receptor alpha 3 Function by Colchicine.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.01143

By:

Muñoz-Montesino, Carola;
Burgos, Carlos F.;
Lara, Cesar O.;
Riquelme, Camila R.;
Flaig, David;
San Martin, Victoria P.;
Aguayo, Luis G.;
Fuentealba, Jorge;
Castro, Patricio A.;
Guzmán, Leonardo;
Yévenes, Gonzalo E.;
Moraga-Cid, Gustavo

Publication type:

Article

To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors?

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00627

By:

Stokes, Leanne;
Bidula, Stefan;
Bibič, Lučka;
Allum, Elizabeth

Publication type:

Article

Pentameric Ligand-Gated Ion Channels as Pharmacological Targets Against Chronic Pain.

Published in:

Frontiers in Pharmacology, 2020, p. 1, doi. 10.3389/fphar.2020.00167

By:

Lara, César O.;
Burgos, Carlos F.;
Moraga-Cid, Gustavo;
Carrasco, Mónica A.;
Yévenes, Gonzalo E.

Publication type:

Article

A variability in response of osteoclasts to zoledronic acid is mediated by smoking-associated modification in the DNA methylome.

Published in:

Clinical Epigenetics, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13148-023-01449-1

By:

Tan, Qihua;
Møller, Anaïs Marie Julie;
Qiu, Chuan;
Madsen, Jonna Skov;
Shen, Hui;
Bechmann, Troels;
Delaisse, Jean-Marie;
Kristensen, Bjarne Winther;
Deng, Hong-Wen;
Karasik, David;
Søe, Kent

Publication type:

Article

Catatonia Associated with Clonazepam Withdrawal.

Published in:

2020

By:

Ithman, Muaid;
Marshall, Levi;
Chandrashekar, Geetha;
Bordoloi, Meelie;
Brandt, Kimberly

Publication type:

Case Study

Electrically-evoked oscillating calcium transients in mono- and co-cultures of iPSC glia and sensory neurons.

Published in:

Frontiers in Cellular Neuroscience, 2023, v. 17, p. 1, doi. 10.3389/fncel.2023.1094070

By:

Lawson, Jennifer;
LaVancher, Elijah;
DeAlmeida, Mauricio;
Black, Bryan James

Publication type:

Article

A narrative review of autophagy in migraine.

Published in:

2025

By:

Huang, Yanan;
Li, Hongyan;
Yu, Qijun;
Pan, Yonghui

Publication type:

Literature Review

State-dependent protein-lipid interactions of a pentameric ligand-gated ion channel in a neuronal membrane.

Published in:

PLoS Computational Biology, 2021, v. 17, n. 2, p. 1, doi. 10.1371/journal.pcbi.1007856

By:

Dämgen, Marc A.;
Biggin, Philip C.

Publication type:

Article

Erythropoietin protects red blood cells from TRAIL1-induced cell death during red blood cell transition in Xenopus laevis.

Published in:

Molecular & Cellular Biochemistry, 2015, v. 398, n. 1/2, p. 73, doi. 10.1007/s11010-014-2206-0

By:

Tamura, Kei;
Takamatsu, Nobuhiko;
Ito, Michihiko

Publication type:

Article

Ligand‐stereoselective allosteric activation of cold‐sensing TRPM8 channels by an H‐bonded homochiral menthol dimer with head‐to‐head or head‐to‐tail.

Published in:: Chirality, 2021, v. 33, n. 11, p. 783, doi. 10.1002/chir.23364
Publication type:: Article

Fluorescence Studies of Nicotinic Acetylcholine Receptor and Its Associated Lipid Milieu: The Influence of Erwin London's Methodological Approaches.

Published in:

Journal of Membrane Biology, 2022, v. 255, n. 4/5, p. 563, doi. 10.1007/s00232-022-00239-9

By:

Barrantes, Francisco J.

Publication type:

Article

Relevance of TRPA1 and TRPM8 channels as vascular sensors of cold in the cutaneous microvasculature.

Published in:

Pflügers Archiv: European Journal of Physiology, 2018, v. 470, n. 5, p. 779, doi. 10.1007/s00424-017-2085-9

By:

Pan, Y.;
Thapa, D.;
Baldissera, L.;
Argunhan, F.;
Aubdool, A. A.;
Brain, S. D.

Publication type:

Article

Homodimeric anoctamin-1, but not homodimeric anoctamin-6, is activated by calcium increases mediated by the P2Y1 and P2X7 receptors.

Published in:

Pflügers Archiv: European Journal of Physiology, 2015, v. 467, n. 10, p. 2121, doi. 10.1007/s00424-015-1687-3

By:

Stolz, Michaela;
Klapperstück, Manuela;
Kendzierski, Thomas;
Detro-dassen, Silvia;
Panning, Anna;
Schmalzing, Günther;
Markwardt, Fritz

Publication type:

Article

Characterization of a Choline-Gated Chloride Channel (LGC-40) from Haemonchus contortus Highlights a Novel Cholinergic Binding Site.

Published in:

Parasitologia, 2025, v. 5, n. 1, p. 12, doi. 10.3390/parasitologia5010012

By:

Nazareth, Kristen;
Habibi, Sarah;
Forrester, Sean G.

Publication type:

Article

凋亡相关斑点样蛋白寡聚阻断剂对小鼠脊髓损伤急性期局部基因转录表达影响的转录组分析.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2022, v. 26, n. 23, p. 3620, doi. 10.12307/2022.659

By:

李璟璐;
王赛男;
王阳阳;
付贵强;
王颖;
胡建国;
唐洁;
吕合作

Publication type:

Article

Structural basis for allosteric agonism of human α7 nicotinic acetylcholine receptors.

Published in:

Cell Discovery, 2025, v. 11, n. 1, p. 1, doi. 10.1038/s41421-025-00788-y

By:

Liu, Sanling;
Zheng, Yining;
Chen, Haopeng;
Li, Xin;
Yan, Qipeng;
Mu, Wenjun;
Fu, Yaning;
Chen, Huan;
Hou, Hongwei;
Liu, Lei;
Tian, Changlin

Publication type:

Article

Delineating the activity of the potent nicotinic acetylcholine receptor agonists (+)‐anatoxin‐a and (−)‐hosieine‐A.

Published in:

Acta Crystallographica: Section F, Structural Biology Communications, 2022, v. 78, n. 9, p. 313, doi. 10.1107/S2053230X22007762

By:

Parker, Holly P.;
Dawson, Alice;
Jones, Mathew J.;
Yan, Rui;
Ouyang, Jie;
Hong, Ran;
Hunter, William N.

Publication type:

Article

Nonsynonymous variations of ion channel-related genes as risk factors in epilepsy.

Published in:

Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2021, v. 38, n. 3, p. 288, doi. 10.52142/omujecm.38.3.15

By:

SÜT, Burcu BİTERGE;
SOYTÜRK, Hayriye

Publication type:

Article

Drosophila nicotinic acetylcholine receptor subunits and their native interactions with insecticidal peptide toxins.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.74322

By:

Korona, Dagmara;
Dirnberger, Benedict;
Giachello, Carlo N. G.;
Queiroz, Rayner M. L.;
Popovic, Rebeka;
Müller, Karin H.;
Minde, David-Paul;
Deery, Michael J.;
Johnson, Glynnis;
Firth, Lucy C.;
Earley, Fergus G.;
Russell, Steven;
Lilley, Kathryn S.

Publication type:

Article

P2Y1 purinergic receptor identified as a diabetes target in a small-molecule screen to reverse circadian _-cell failure.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.75132

By:

Marcheva, Biliana;
Weidemann, Benjamin J.;
Akihiko Taguchi;
Perelis, Mark;
Ramsey, Kathryn Moynihan;
Newman, Marsha V.;
Yumiko Kobayashi;
Chiaki Omura;
Fox, Jocelyn E. Manning;
Haopeng Lin;
Macdonald, Patrick E.;
Bass, Joseph

Publication type:

Article

Markov state models of proton- and pore-dependent activation in a pentameric ligand-gated ion channel.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.68369

By:

Bergh, Cathrine;
Heusser, Stephanie A.;
Howard, Rebecca;
Lindahl, Erik

Publication type:

Article

Mutational analysis to explore long-range allosteric couplings involved in a pentameric channel receptor pre-activation and activation.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.60682

By:

Lefebvre, Solène N.;
Taly, Antoine;
Menny, Anaïs;
Medjebeur, Karima;
Corringer, Pierre-Jean

Publication type:

Article

Deletion of P2X7 Receptor Decreases Basal Glutathione Level by Changing Glutamate-Glutamine Cycle and Neutral Amino Acid Transporters.

Published in:

Cells (2073-4409), 2020, v. 9, n. 4, p. 995, doi. 10.3390/cells9040995

By:

Park, Hana;
Kim, Ji-Eun

Publication type:

Article

High Expression of GABA A Receptor β Subunit Genes Is Associated with Longer Overall Survival in Medulloblastoma.

Published in:

Brain Sciences (2076-3425), 2024, v. 14, n. 11, p. 1146, doi. 10.3390/brainsci14111146

By:

Monteiro, Jander M.;
Dalmolin, Matheus;
Fernandes, Marcelo A. C.;
Ramos, Jaqueline I. R.;
Ribas, Carmen A. P. M.;
Tabushi, Fernando I.;
Roesler, Rafael;
Isolan, Gustavo R.

Publication type:

Article

Interplay between Gating and Block of Ligand-Gated Ion Channels.

Published in:

Brain Sciences (2076-3425), 2020, v. 10, n. 12, p. 928, doi. 10.3390/brainsci10120928

By:

Phillips, Matthew B.;
Nigam, Aparna;
Johnson, Jon W.

Publication type:

Article

Editorial: The GABAA receptor: a target of pharmacologically active molecules.

Published in:

Frontiers in Pharmacology, 2024, p. 1, doi. 10.3389/fphar.2024.1440937

By:

Ernst, Margot;
Wei Lu;
Mattei, César

Publication type:

Article

Study, by use of coarse-grained models, of the functionally crucial residues and allosteric pathway of anesthetic regulation of the Gloeobacter violaceus ligand-gated ion channel.

Published in:

European Biophysics Journal, 2014, v. 43, n. 12, p. 623, doi. 10.1007/s00249-014-0992-7

By:

Li, Xing;
Xie, Fang;
Zhang, Jing;
Su, Ji

Publication type:

Article

Structural and dynamic mechanisms of GABAA receptor modulators with opposing activities.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-32212-4

By:

Zhu, Shaotong;
Sridhar, Akshay;
Teng, Jinfeng;
Howard, Rebecca J.;
Lindahl, Erik;
Hibbs, Ryan E.

Publication type:

Article

In vivo spatiotemporal control of voltage-gated ion channels by using photoactivatable peptidic toxins.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-27974-w

By:

Montnach, Jérôme;
Blömer, Laila Ananda;
Lopez, Ludivine;
Filipis, Luiza;
Meudal, Hervé;
Lafoux, Aude;
Nicolas, Sébastien;
Chu, Duong;
Caumes, Cécile;
Béroud, Rémy;
Jopling, Chris;
Bosmans, Frank;
Huchet, Corinne;
Landon, Céline;
Canepari, Marco;
De Waard, Michel

Publication type:

Article

Elucidation of Medusozoan (Jellyfish) Venom Constituent Activities Using Constellation Pharmacology.

Published in:

Toxins, 2024, v. 16, n. 10, p. 447, doi. 10.3390/toxins16100447

By:

Yanagihara, Angel A.;
Giglio, Matías L.;
Hurwitz, Kikiana;
Kadler, Raechel;
Espino, Samuel S.;
Raghuraman, Shrinivasan;
Olivera, Baldomero M.

Publication type:

Article

Anti-Inflammatory Activity of 1,4-Naphthoquinones Blocking P2X7 Purinergic Receptors in RAW 264.7 Macrophage Cells.

Published in:

Toxins, 2023, v. 15, n. 1, p. 47, doi. 10.3390/toxins15010047

By:

Kozlovskiy, Sergei A.;
Pislyagin, Evgeny A.;
Menchinskaya, Ekaterina S.;
Chingizova, Ekaterina A.;
Sabutski, Yuriy E.;
Polonik, Sergey G.;
Likhatskaya, Galina N.;
Aminin, Dmitry L.

Publication type:

Article

Nicotinic Acetylcholine Receptors Are Novel Targets of APETx-like Toxins from the Sea Anemone Heteractis magnifica.

Published in:

Toxins, 2022, v. 14, n. 10, p. N.PAG, doi. 10.3390/toxins14100697

By:

Kalina, Rimma S.;
Kasheverov, Igor E.;
Koshelev, Sergey G.;
Sintsova, Oksana V.;
Peigneur, Steve;
Pinheiro-Junior, Ernesto Lopes;
Popov, Roman S.;
Chausova, Victoria E.;
Monastyrnaya, Margarita M.;
Dmitrenok, Pavel S.;
Isaeva, Marina P.;
Tytgat, Jan;
Kozlov, Sergey A.;
Kozlovskaya, Emma P.;
Leychenko, Elena V.;
Gladkikh, Irina N.

Publication type:

Article

Electromagnetic radiation modulates synchronization in cortical neurons of Macaque brain.

Published in:

International Journal of Modern Physics C: Computational Physics & Physical Computation, 2019, v. 30, n. 8, p. N.PAG, doi. 10.1142/S0129183119500475

By:

Vinaya, Mary;
Ignatius, Rose P.

Publication type:

Article

Manganese-Enhanced MRI Reflects Both Activity-Independent and Activity-Dependent Uptake within the Rat Habenulomesencephalic Pathway.

Published in:

PLoS ONE, 2015, v. 10, n. 5, p. 1, doi. 10.1371/journal.pone.0127773

By:

Wang, Leiming;
Lu, Hanbing;
Brown, P. Leon;
Rea, William;
Vaupel, Bruce;
Yang, Yihong;
Stein, Elliot;
Shepard, Paul D.

Publication type:

Article

A Truncation Variant of the Cation Channel P2RX5 Is Upregulated during T Cell Activation.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0104692

By:

Abramowski, Pierre;
Ogrodowczyk, Christoph;
Martin, Roland;
Pongs, Olaf

Publication type:

Article

Serotonin 5-HT3 Receptor-Mediated Vomiting Occurs via the Activation of Ca2+/CaMKII-Dependent ERK1/2 Signaling in the Least Shrew (Cryptotis parva).

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0104718

By:

Zhong, Weixia;
Hutchinson, Tarun E.;
Chebolu, Seetha;
Darmani, Nissar A.

Publication type:

Article

Crosslinking Constraints and Computational Models as Complementary Tools in Modeling the Extracellular Domain of the Glycine Receptor.

Published in:

PLoS ONE, 2014, v. 9, n. 7, p. 1, doi. 10.1371/journal.pone.0102571

By:

Liu, Zhenyu;
Szarecka, Agnieszka;
Yonkunas, Michael;
Speranskiy, Kirill;
Kurnikova, Maria;
Cascio, Michael

Publication type:

Article

Novel interplay between agonist and calcium binding sites modulates drug potentiation of α7 acetylcholine receptor.

Published in:

Cellular & Molecular Life Sciences, 2024, v. 81, n. 1, p. 1, doi. 10.1007/s00018-024-05374-1

By:

Mukhtasimova, Nuriya;
Bouzat, Cecilia;
Sine, Steven M.

Publication type:

Article

Optogenetic Determination of Dynamic and Cell-Type-Specific Inhibitory Reversal Potentials.

Published in:

Journal of Neuroscience, 2024, v. 44, n. 20, p. 1, doi. 10.1523/JNEUROSCI.1392-23.2024

By:

Burman, Richard J.;
Diviney, Tara;
Călin, Alexandru;
Gothard, Gemma;
Jouhanneau, Jean-Sébastien M.;
Poulet, James F. A.;
Sen, Arjune;
Akerman, Colin J.

Publication type:

Article