Works matching DE "INSULIN-like growth factor receptors"

Results: 612

Targeting the Aryl Hydrocarbon Receptor to Attenuate IGF1R Signaling in Thyroid Eye Disease.

Published in:

Thyroid, 2025, v. 35, n. 5, p. 527, doi. 10.1089/thy.2024.0529

By:

Roztocil, Elisa;
Husain, Farha;
Patrick, Charkira C.;
Feldon, Steven E.;
Woeller, Collynn F.

Publication type:

Article

Rational Method for Structural Simplification as Key Step in Hit Discovery: The Case of FGFR2 and IGF1R Dual Inhibitors.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 9, p. 4457, doi. 10.3390/ijms26094457

By:

Torres-Urtizberea, Endika;
Borrell, José I.;
Puig de la Bellacasa, Raimon;
Estrada-Tejedor, Roger

Publication type:

Article

Nicotine‐driven enhancement of tumor malignancy in triple‐negative breast cancer via additive regulation of CHRNA9 and IGF1R.

Published in:

Journal of Pathology, 2025, v. 266, n. 2, p. 230, doi. 10.1002/path.6423

By:

Kuo, Yung‐Che;
Chen, Chi‐Long;
Lee, Kha‐Liang;
Wang, Hsiao‐Feng;
Drew, Victor James;
Lan, Pei‐Chi;
Ho, Yuan‐Soon;
Huang, Yen‐Hua

Publication type:

Article

Growth-Blocking Peptides As Nutrition-Sensitive Signals for Insulin Secretion and Body Size Regulation.

Published in:

PLoS Biology, 2016, v. 14, n. 2, p. 1, doi. 10.1371/journal.pbio.1002392

By:

Koyama, Takashi;
Mirth, Christen K.

Publication type:

Article

Hemangioma-related gene polymorphisms in the pathogenesis of intraventricular hemorrhage in preterm infants.

Published in:

Child's Nervous System, 2023, v. 39, n. 6, p. 1589, doi. 10.1007/s00381-023-05824-4

By:

Kosik, Katarzyna;
Szpecht, Dawid;
Karbowski, Łukasz;
Al-Saad, Salwan R.;
Chmielarz-Czarnocińska, Anna;
Minta, Marcin;
Sowińska, Anna;
Strauss, Ewa

Publication type:

Article

Evaluation of Tc-Z-GGGC affibody molecule, a new probe for imaging of insulin-like growth factor type 1 receptor expression.

Published in:

Amino Acids, 2015, v. 47, n. 2, p. 303, doi. 10.1007/s00726-014-1859-z

By:

Mitran, Bogdan;
Altai, Mohamed;
Hofström, Camilla;
Honarvar, Hadis;
Sandström, Mattias;
Orlova, Anna;
Tolmachev, Vladimir;
Gräslund, Torbjörn

Publication type:

Article

The many faces of insulin-like peptide signalling in the brain.

Published in:

Nature Reviews Neuroscience, 2012, v. 13, n. 4, p. 225, doi. 10.1038/nrn3209

By:

Fernandez, Ana M.;
Torres-Alemán, Ignacio

Publication type:

Article

Prognostic importance of PTEN, EGFR, HER-2, and IGF-1R in gastric cancer patients treated with postoperative chemoradiation.

Published in:

Turkish Journal of Medical Sciences, 2019, v. 49, n. 4, p. 1025, doi. 10.3906/sag-1802-34

By:

BENLİ YAVUZ, Berrin;
KOÇ, Mehmet;
KOZACIOĞLU, Sümeyye;
KANYILMAZ, Gül;
AKTAN, Meryem

Publication type:

Article

Plasma growth hormone, insulin-like growth factor I, and insulin-like growth factor binding proteins in pigs with divergent genetic merit for postweaning average daily gain1.

Published in:: Journal of Animal Science, 1995, v. 73, n. 6, p. 1776, doi. 10.2527/1995.7361776x
Publication type:: Article

Endogenous Insulin-Like Growth Factor II Mediates Growth in Preimplantation Mouse Embryos Through the Insulin-Like Growth Factor I Receptor: A Case Study on the Role of Growth Factors in Mammalian Development.

Published in:: Journal of Animal Science, 1992, v. 70, p. 42, doi. 10.2527/1992.70suppl_242x
Publication type:: Article

Obesity and breast cancer.

Published in:

Oncolog-Hematolog, 2019, n. 48, p. 17, doi. 10.26416/onhe.48.3.2019.2563

By:

Pantelimon, Iuliana;
Tebeică, Ana-Maria

Publication type:

Article

The growth Promoting Effect of Beta-glucan in Comparison with Sodium Butyrate on Broiler Chicks.

Published in:

Alexandria Journal of Veterinary Sciences, 2015, v. 44, n. 1, p. 23, doi. 10.5455/ajvs.163992

By:

El-Sawy, Abd El-Salam F.;
El-Maddawy, Zeynab Kh.;
Ibrahiem, Hawary S.;
Bo-Ghazel, El-Sadeq

Publication type:

Article

Extracellular vesicles derived from macrophages display glycyl‐tRNA synthetase 1 and exhibit anti‐cancer activity.

Published in:

Journal of Extracellular Vesicles, 2020, v. 10, p. 1, doi. 10.1002/jev2.12029

By:

Goughnour, Peter C.;
Park, Min Chul;
Kim, Sang Bum;
Jun, Sangmi;
Yang, Won Suk;
Chae, Sehyun;
Cho, Seongmin;
Song, Chihong;
Lee, Ji‐Hyun;
Hyun, Jae Kyung;
Kim, Byung Gyu;
Hwang, Daehee;
Jung, Hyun Suk;
Gho, Yong Song;
Kim, Sunghoon

Publication type:

Article

Extracellular vesicles derived from macrophages display glycyl‐tRNA synthetase 1 and exhibit anti‐cancer activity.

Published in:

Journal of Extracellular Vesicles, 2020, v. 10, n. 1, p. 1, doi. 10.1002/jev2.12029

By:

Goughnour, Peter C.;
Park, Min Chul;
Kim, Sang Bum;
Jun, Sangmi;
Yang, Won Suk;
Chae, Sehyun;
Cho, Seongmin;
Song, Chihong;
Lee, Ji‐Hyun;
Hyun, Jae Kyung;
Kim, Byung Gyu;
Hwang, Daehee;
Jung, Hyun Suk;
Gho, Yong Song;
Kim, Sunghoon

Publication type:

Article

Current therapeutic landscape and resistance mechanisms to larotrectinib.

Published in:

Cancer Biology & Medicine, 2023, v. 20, n. 12, p. 967, doi. 10.20892/j.issn.2095-3941.2023.0471

By:

Weiji Xie;
Jiaqian Xu;
Suying Lu;
Yizhuo Zhang

Publication type:

Article

Skin epigenetics.

Published in:

Experimental Dermatology, 2021, v. 30, n. 8, p. 1004, doi. 10.1111/exd.14418

By:

Andersen, Bogi;
Millar, Sarah

Publication type:

Article

MicroRNA‐379 mediates pigmentation, migration and proliferation of melanocytes by targeting the insulin‐like growth factor 1 receptor.

Published in:

Experimental Dermatology, 2020, v. 29, n. 5, p. 467, doi. 10.1111/exd.14095

By:

Liu, Bo;
Zhang, Junzhen;
Hu, Shixiong;
Qi, Shuhui;
Jia, Qiong;
Yang, Wanyun;
Yang, Shanshan;
Ji, Kaiyuan;
Liu, Xuexian;
Dong, Changsheng;
Fan, Ruiwen

Publication type:

Article

Igf1r signalling acts on the anagen-to-catagen transition in the hair cycle.

Published in:

Experimental Dermatology, 2017, v. 26, n. 9, p. 785, doi. 10.1111/exd.13287

By:

Castela, Mathieu;
Linay, Fabien;
Roy, Edwige;
Moguelet, Philippe;
Xu, Jie;
Holzenberger, Martin;
Khosrotehrani, Kiarash;
Aractingi, Selim

Publication type:

Article

Klotho inhibits IGF1R/PI3K/AKT signalling pathway and protects the heart from oxidative stress during ischemia/reperfusion injury.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-47686-5

By:

Olejnik, Agnieszka;
Radajewska, Anna;
Krzywonos-Zawadzka, Anna;
Bil-Lula, Iwona

Publication type:

Article

Novel THBS1::IGF1R fusion in myopericytic tumour.

Published in:

Histopathology, 2024, v. 85, n. 1, p. 197, doi. 10.1111/his.15186

By:

Kato, Kenichiro;
Yamashita, Kyoko;
Dobashi, Akito;
Togashi, Yuki;
Baba, Satoko;
Ae, Keisuke;
Matsumoto, Seiichi;
Takeuchi, Kengo

Publication type:

Article

Antagonism of brain insulin-like growth factor-1 receptors blocks estradiol effects on memory and levels of hippocampal synaptic proteins in ovariectomized rats.

Published in:

Psychopharmacology, 2014, v. 231, n. 5, p. 899, doi. 10.1007/s00213-013-3310-7

By:

Nelson, Britta;
Springer, Rachel;
Daniel, Jill

Publication type:

Article

Downregulation of IGFBP2 is associated with resistance to IGF1R therapy in rhabdomyosarcoma.

Published in:

Oncogene, 2014, v. 33, n. 50, p. 5697, doi. 10.1038/onc.2013.509

By:

Kang, Z;
Yu, Y;
Zhu, Y J;
Davis, S;
Walker, R;
Meltzer, P S;
Helman, L J;
Cao, L

Publication type:

Article

Expanding the clinical spectrum of chromosome 15q26 terminal deletions associated with IGF-1 resistance.

Published in:

2017

By:

McGrath, Niamh;
Sharif, Farhana;
Murphy, Nuala;
Lynch, Sally;
O'Riordan, Aisling;
O'Grady, Michael;
Franklin, Orla;
O'Riordan, Aisling M;
Murphy, Nuala P;
Lynch, Sally Ann;
O'Grady, Michael J

Publication type:

journal article

Re: "Thyroid Eye Disease: A New Name, a New Guide, and a New Era" by Davies.

Published in:

Thyroid, 2023, v. 33, n. 4, p. 531, doi. 10.1089/thy.2022.0697

By:

Korff, Jeffrey

Publication type:

Article

M1-Like Macrophages Modulate Fibrosis and Inflammation of Orbital Fibroblasts in Graves' Orbitopathy: Potential Relevance to Soluble Interleukin-6 Receptor.

Published in:

Thyroid, 2023, v. 33, n. 3, p. 338, doi. 10.1089/thy.2022.0254

By:

Lu, Yi;
Wang, Yi;
Wang, Yang;
Wu, Yu;
Huang, Yazhuo;
Liu, Xingtong;
Zhang, Shuo;
Zhong, Sisi;
Li, Yinwei;
Li, Bin;
Sun, Jing;
Fang, Sijie;
Zhou, Huifang

Publication type:

Article

A Multicenter, Single-Blind, Case-Control, Immunohistochemical Study of Orbital Tissue in Thyroid Eye Disease.

Published in:

Thyroid, 2022, v. 32, n. 12, p. 1547, doi. 10.1089/thy.2022.0173

By:

Hai, Yuan-Ping;
Saeed, Mohamed E.M.;
Ponto, Katharina A.;
Elflein, Heike M.;
Lee, Alan Chun Hong;
Fang, Sijie;
Zhou, Huifang;
Frommer, Lara;
Längericht, Jan;
Efferth, Thomas;
Kahaly, George J.

Publication type:

Article

Mechanisms in Graves Eye Disease: Apoptosis as the End Point of Insulin-Like Growth Factor 1 Receptor Inhibition.

Published in:

Thyroid, 2022, v. 32, n. 4, p. 429, doi. 10.1089/thy.2021.0176

By:

Morshed, Syed A.;
Ma, Risheng;
Latif, Rauf;
Davies, Terry F.

Publication type:

Article

Response to Krieger et al. re: 'TSHR/IGF-1R Cross-Talk, Not IGF-1R Stimulating Antibodies, Mediates Graves' Ophthalmopathy Pathogenesis' ( Thyroid 2017;27:746-747).

Published in:

Thyroid, 2017, v. 27, n. 11, p. 1458, doi. 10.1089/thy.2017.0281

By:

Smith, Terry J.;
Janssen, Joseph A.M.J.L.

Publication type:

Article

TSHR/IGF-1R Cross-Talk, Not IGF-1R Stimulating Antibodies, Mediates Graves' Ophthalmopathy Pathogenesis.

Published in:

Thyroid, 2017, v. 27, n. 5, p. 746, doi. 10.1089/thy.2017.0105

By:

Krieger, Christine C.;
Neumann, Susanne;
Marcus-Samuels, Bernice;
Gershengorn, Marvin C.

Publication type:

Article

Activation of the insulin receptor by insulin-like growth factor 2.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46990-6

By:

An, Weidong;
Hall, Catherine;
Li, Jie;
Hung, Albert;
Wu, Jiayi;
Park, Junhee;
Wang, Liwei;
Bai, Xiao-chen;
Choi, Eunhee

Publication type:

Article

Novel alternative splice variant of IGF-1R and its mRNA expression patterns in BaMa and Landrace pigs.

Published in:

Indian Journal of Animal Research, 2021, v. 55, n. 3, p. 271, doi. 10.18805/ijar.B-1107

By:

Rui Yang;
Lijie Dong;
Songcai Liu;
Yunyun Cheng;
Wenzhen Wei;
Jie Song;
Haoyang Li;
Hongwei Geng;
Linlin Hao;
Ying Zhang

Publication type:

Article

IGF-1R mediates crosstalk between nasopharyngeal carcinoma cells and osteoclasts and promotes tumor bone metastasis.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2024, v. 43, n. 1, p. 1, doi. 10.1186/s13046-024-02970-8

By:

Yang, Kaifan;
Hu, Yanjun;
Feng, Yuanyuan;
Li, Kaiqun;
Zhu, Ziyan;
Liu, Shuyi;
Lin, Yanling;
Yu, Bin

Publication type:

Article

The regulation of insulin receptor/insulin-like growth factor 1 receptor ratio, an important factor for breast cancer prognosis, by TRIP-Br1.

Published in:

Journal of Hematology & Oncology, 2022, v. 15, n. 1, p. 1, doi. 10.1186/s13045-022-01303-6

By:

Nguyen, Thi Ngoc Quynh;
Jung, Samil;
Nguyen, Hai Anh;
Lee, BeomSuk;
Vu, Son Hai;
Myagmarjav, Davaajargal;
Eum, Hye Hyeon;
Lee, Hae-Ock;
Jo, Taeyeon;
Choi, Yeongseon;
Lee, Myeong-Sok

Publication type:

Article

Pharmacological profiling of a dual FAK/IGF-1R kinase inhibitor TAE226 in cellular and in vivo tumor models.

Published in:

BMC Research Notes, 2019, v. 12, n. 1, p. N.PAG, doi. 10.1186/s13104-019-4389-7

By:

Fukami, Shigemi;
Tomioka, Daisaku;
Murakami, Yutaka;
Honda, Toshiyuki;
Hatakeyama, Shinji

Publication type:

Article

Retraction: MNK1-Induced eIF-4E Phosphorylation in Myeloma Cells: A Pathway Mediating IL-6-Induced Expansion and Expression of Genes Involved in Metabolic and Proteotoxic Responses.

Published in:: 2023
Publication type:: Correction Notice

IGF-1 Combined with OPN Promotes Neuronal Axon Growth in Vitro Through the IGF-1R/Akt/mTOR Signaling Pathway in Lipid Rafts.

Published in:

Neurochemical Research, 2023, v. 48, n. 10, p. 3190, doi. 10.1007/s11064-023-03971-3

By:

Zhao, Qin;
Su, Hong;
Jiang, Wei;
Luo, Haodong;
Pan, Lu;
Liu, Yuan;
Yang, Ce;
Yin, Ying;
Yu, Lehua;
Tan, Botao

Publication type:

Article

Baicalein Ameliorates Epilepsy Symptoms in a Pilocarpine-Induced Rat Model by Regulation of IGF1R.

Published in:

Neurochemical Research, 2020, v. 45, n. 12, p. 3021, doi. 10.1007/s11064-020-03150-8

By:

Fu, Pengfei;
Yuan, Qiang;
Sun, Yirui;
Wu, Xin;
Du, Zhuoyin;
Li, Zhiqi;
Yu, Jin;
Lv, Ke;
Hu, Jin

Publication type:

Article

Insulin receptor signaling mediates APP processing and β-amyloid accumulation without altering survival in a transgenic mouse model of Alzheimer's disease.

Published in:

Age (0161-9152), 2013, v. 35, n. 1, p. 83, doi. 10.1007/s11357-011-9333-2

By:

Stöhr, Oliver;
Schilbach, Katharina;
Moll, Lorna;
Hettich, Moritz;
Freude, Susanna;
Wunderlich, F.;
Ernst, Marianne;
Zemva, Johanna;
Brüning, Jens;
Krone, Wilhelm;
Udelhoven, Michael;
Schubert, Markus

Publication type:

Article

Jeremy Jass Prize for Research Excellence in Pathology 2023.

Published in:: Journal of Pathology, 2025, v. 265, n. 2, p. 244, doi. 10.1002/path.6389
Publication type:: Article

Hsa-miR-6165 downregulates insulin-like growth factor-1 receptor (IGF-1R) expression and enhances apoptosis in SW480 cells.

Published in:

Biological Chemistry, 2020, v. 401, n. 4, p. 477, doi. 10.1515/hsz-2018-0421

By:

Hassanlou, Maryam;
Soltani, Bahram M.;
Medlej, Abdallah;
Kay, Maryam;
Mowla, Seyed Javad

Publication type:

Article

Mechanism of cargo recognition by retromer-linked SNX-BAR proteins.

Published in:

PLoS Biology, 2020, v. 18, n. 3, p. 1, doi. 10.1371/journal.pbio.3000631

By:

Yong, Xin;
Zhao, Lin;
Deng, Wankun;
Sun, Hongbin;
Zhou, Xue;
Mao, Lejiao;
Hu, Wenfeng;
Shen, Xiaofei;
Sun, Qingxiang;
Billadeau, Daniel D.;
Xue, Yu;
Jia, Da

Publication type:

Article

Phosphorylated insulin-like growth factor-1 receptor (pIGF1R) is a poor prognostic factor in brain metastases from lung adenocarcinomas.

Published in:

Journal of Neuro-Oncology, 2013, v. 115, n. 1, p. 61, doi. 10.1007/s11060-013-1194-3

By:

Wu, Pei-Fang;
Huang, Wen-Chang;
Yang, James;
Lu, Yen-Shen;
Shih, Jin-Yuan;
Wu, Shang-Gin;
Lin, Ching-Hung;
Cheng, Ann-Lii

Publication type:

Article

Acupuncture Reduces Hypertrophy and Cardiac Fibrosis, and Improves Heart Function in Mice with Diabetic Cardiomyopathy.

Published in:

Cardiovascular Drugs & Therapy, 2020, v. 34, n. 6, p. 835, doi. 10.1007/s10557-020-07043-4

By:

Ye, Yumei;
Birnbaum, Yochai;
Widen, Steven G.;
Zhang, Zhaohui;
Zhu, Shipeng;
Bajaj, Mandeep;
Chen, Huan

Publication type:

Article

The nuclear translocation of insulin‐like growth factor receptor and its significance in cancer cell survival.

Published in:

Cell Biochemistry & Function, 2020, v. 38, n. 4, p. 347, doi. 10.1002/cbf.3479

By:

Chughtai, Shahzaib

Publication type:

Article

Correlations of IGF-1R and COX-2 Expressions with Ras and BRAF Genetic Mutations, Clinicopathological Features and Prognosis of Colorectal Cancer Patients.

Published in:

Pathology & Oncology Research, 2018, v. 24, n. 1, p. 45, doi. 10.1007/s12253-017-0195-5

By:

Jin, Mei;
Long, Zi-Wen;
Yang, Jing;
Lin, Xiang

Publication type:

Article

Comparative Molecular Characterization and Pharmacokinetics of IgG1-Fc and Engineered Fc Human Antibody Variants to Insulin-like Growth Factor 2 Receptor (IGF2R).

Published in:

Molecules, 2023, v. 28, n. 15, p. 5839, doi. 10.3390/molecules28155839

By:

Prabaharan, Chandra B.;
Giri, Sabeena;
Allen, Kevin J. H.;
Bato, Katrina E. M.;
Mercado, Therese R.;
Malo, Mackenzie E.;
Carvalho, Jorge L. C.;
Dadachova, Ekaterina;
Uppalapati, Maruti

Publication type:

Article

Extended-Synaptotagmin 1 Enhances Liver Cancer Progression Mediated by the Unconventional Secretion of Cytosolic Proteins.

Published in:

Molecules, 2023, v. 28, n. 10, p. 4033, doi. 10.3390/molecules28104033

By:

Yamada, Kohji;
Hannya, Yoshito;
Oikawa, Tsunekazu;
Yoshida, Ayano;
Katagiri, Kuniko;
Yoshida, Saishu;
Koizumi, Rei;
Tago, Naoko;
Shimoyama, Yuya;
Kawamura, Akira;
Mochimaru, Yuta;
Eto, Ken;
Yoshida, Kiyotsugu

Publication type:

Article

Effect of Pinoresinol and Vanillic Acid Isolated from Catalpa bignonioides on Mouse Myoblast Proliferation via the Akt/mTOR Signaling Pathway.

Published in:

Molecules, 2022, v. 27, n. 17, p. 5397, doi. 10.3390/molecules27175397

By:

Kim, Seo-Young;
Kwon, Sung-Pil;
Park, SeonJu;
Cho, Su-Hyeon;
Oh, Youngse;
Kim, Seung Hyun;
Park, Yoon Ho;
Jung, Hyun Suk;
Lee, Deug-chan;
Jeong, Hoibin;
Kim, Kil-Nam

Publication type:

Article

The Antioxidant, Anti-Inflammatory, and Neuroprotective Properties of the Synthetic Chalcone Derivative AN07.

Published in:

Molecules, 2020, v. 25, n. 12, p. 2907, doi. 10.3390/molecules25122907

By:

Chen, Yih-Fung;
Wu, Sheng-Nan;
Gao, Jia-Mao;
Liao, Zhi-Yao;
Tseng, Yu-Ting;
Fülöp, Ferenc;
Chang, Fang-Rong;
Lo, Yi-Ching;
Lavandera, Jose Luis

Publication type:

Article

A Novel Receptor Tyrosine Kinase Switch Promotes Gastrointestinal Stromal Tumor Drug Resistance.

Published in:

Molecules, 2017, v. 22, n. 12, p. 2152, doi. 10.3390/molecules22122152

By:

Boichuk, Sergei;
Galembikova, Aigul;
Dunaev, Pavel;
Valeeva, Elena;
Shagimardanova, Elena;
Gusev, Oleg;
Khaiboullina, Svetlana

Publication type:

Article