Works matching DE "CELL lines"

Results: 5000

Exploring the neuroprotective mechanisms of Jiawei Suanzaoren decoction in depression: insights from network pharmacology and molecular docking.

Published in:

BMC Complementary Medicine & Therapies, 2025, v. 25, n. 1, p. 1, doi. 10.1186/s12906-025-04939-2

By:

Ma, Ruiting;
Zhang, Wenjing;
Chen, Lixia;
Tong, Lijun

Publication type:

Article

Transcriptome Analysis of Porphyromonas gingivalis Lipopolysaccharide‐Induced Early Gene Expression in Human Gingival Keratinocytes.

Published in:

Journal of Periodontal Research, 2025, v. 60, n. 4, p. 380, doi. 10.1111/jre.13353

By:

Ostadkarampour, Mahyar;
Putnins, Edward E.

Publication type:

Article

Characterization of a suspension Vero cell line for viral vaccine production.

Published in:

NPJ Vaccines, 2025, v. 10, n. 1, p. 1, doi. 10.1038/s41541-025-01157-2

By:

Bourigault, Léa;
Bresson, Corinne;
Jean, Christian;
Chevalard, Christophe;
Kloutz, Mathilde;
Soulet, Damien;
Pelissier, Fleurine;
Richard, Stéphanie;
Bassard, Isabelle;
Sève, Nicolas;
Charretier, Cédric;
Pain, Bertrand

Publication type:

Article

RETRACTION: Single‐Cell Transcriptome Sequencing Analysis Reveals Intra‐Tumor Heterogeneity in Esophageal Squamous Cell Carcinoma.

Published in:: 2025
Publication type:: Correction Notice

ESCRT-I and PTPN23 mediate microautophagy of ubiquitylated tau aggregates.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 6, p. 1, doi. 10.1083/jcb.202406120

By:

Yusen Men;
Shoshiro Hirayama;
Shinpei Ao;
Yasuyuki Sakurai;
Yuri Shibata;
Megan Lo;
Yusuke Sato;
Shigeo Murata

Publication type:

Article

Extracellular vesicles adhere to cells primarily by interactions of integrins and GM1 with laminin.

Published in:

Journal of Cell Biology, 2025, v. 224, n. 6, p. 1, doi. 10.1083/jcb.202404064

By:

Tatsuki Isogai;
Hirosawa, Koichiro M.;
Miki Kanno;
Ayano Sho;
Kasai, Rinshi S.;
Naoko Komura;
Hiromune Ando;
Keiko Furukawa;
Yuhsuke Ohmi;
Koichi Furukawa;
Yasunari Yokota;
Suzuki, Kenichi G. N.

Publication type:

Article

Molecular characterization of cytotoxic and resistance mechanisms induced by NCX 4040, a novel NO-NSAID, in pancreatic cancer cell lines<sup>*</sup>.

Published in:

Apoptosis, 2006, v. 11, n. 8, p. 1321, doi. 10.1007/s10495-006-6986-x

By:

Rosetti, Marco;
Tesei, Anna;
Ulivi, Paola;
Fabbri, Francesco;
Vannini, Ivan;
Brigliadori, Giovanni;
Amadori, Dino;
Bolla, Manlio;
Zoli, Wainer

Publication type:

Article

Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21<sup>cip1/waf1</sup>.

Published in:

Apoptosis, 2006, v. 11, n. 8, p. 1299, doi. 10.1007/s10495-006-8760-5

By:

Bodo, Juraj;
Jakubikova, Jana;
Chalupa, Ivan;
Bartosova, Zdena;
Horakova, Katarina;
Floch, Lubomir;
Sedlak, Jan

Publication type:

Article

Substitution of Glutamic Acid at Position 71 of DRβ1*04:01 and Collagen‐Specific Tolerance Without Alloreactivity.

Published in:

Arthritis & Rheumatology, 2025, v. 77, n. 5, p. 526, doi. 10.1002/art.43067

By:

Jha, Vibha;
Freed, Brian M.;
Sunderhaus, Elizabeth R.;
Lee, Jessica E.;
Prage, Edward B.;
Miglani, Manjula;
Rosloniec, Edward F.;
Matsuda, Jennifer L.;
Coulombe, Marilyne G.;
McKee, Amy S.;
Roark, Christina L.

Publication type:

Article

VALIDATION OF IN-VITRO ANTI-CANCER ACTIVITY OF SIDDHA METALLO-MINERAL FORMULATION NANDHI MEZHUGU AGAINST TM3 CELL LINES.

Published in:

Bulletin of Pure & Applied Sciences-Zoology, 2024, v. 43, p. 867

By:

Mohana Jeevanath, Sathya Rathish;
Annamalai, Siva;
Thavaseelan, Jeyaveeran;
Rajan, Chandrasekar;
Shanmugavel, Aravind Kumar;
Ramachansdran, Madhavan

Publication type:

Article

A dual readout embryonic zebrafish xenograft model of rhabdomyosarcoma to assess clinically relevant multi-receptor tyrosine kinase inhibitors.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1547202

By:

Wragg, Joseph W.;
Gray, Emma L.;
Monteiro, Rui;
Morris, Jo R.;
Beggs, Andrew D.;
Müller, Ferenc;
Gatz, Susanne A.

Publication type:

Article

Dual Targeting of Pim and PI3 Kinases in Mature T‐Cell Lymphoma.

Published in:

European Journal of Haematology, 2025, v. 115, n. 1, p. 82, doi. 10.1111/ejh.14420

By:

Lohrberg, M.;
Heber, M.;
Ries, L.;
Markus, K.;
Ksionsko, N.;
Schmidt, N.;
Nothnick, G.;
Thielking, L.;
O'Neill, M.;
Martínéz‐González, S.;
Blanco‐Aparicio, C.;
Pastor, J.;
Cunningham, D.;
Koch, R.

Publication type:

Article

积雪草苷通过cAMP/PKA/CREB 信号通路抑制肝细胞癌Huh7 细胞的恶性生物学行为.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 3, p. 294, doi. 10.3872/j.issn.1007-385x.2025.03.009

By:

刘志超;
党同科;
满高亚;
陈鹏

Publication type:

Article

圣草次苷通过抑制STAT3/GPX4 通路诱导食管癌KYSE30 细胞铁死亡.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 3, p. 281, doi. 10.3872/j.issn.1007-385x.2025.03.007

By:

江蒲;
张娜;
高坤;
靳晶

Publication type:

Article

早期肝癌相关抗原CTAG1A在肝细胞癌组织与细胞中的表达及其细胞毒性T淋巴细胞抗原表位鉴定

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 3, p. 270, doi. 10.3872/j.issn.1007-385x.2025.03.006

By:

刘傅言;
危晏平;
付靖波;
李亮;
王红阳

Publication type:

Article

负载BMSC来源纳米囊泡的硒化透明质酸水凝胶的制备及其对胶质瘤 GL261 细胞的杀伤作用

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 3, p. 247, doi. 10.3872/j.issn.1007-385x.2025.03.003

By:

张转转;
周旋;
陈翠敏;
张停琳;
高洁

Publication type:

Article

PD-1高表达细菌质膜囊泡的构建及对小鼠肺癌移植瘤组织的靶向性评估.

Published in:

Chinese Journal of Cancer Biotherapy, 2025, v. 32, n. 3, p. 239, doi. 10.3872/j.issn.1007-385x.2025.03.002

By:

徐秀杰;
张静云;
范峻晨;
蒋灵馨;
张娜;
郑猛超;
龙雨飞;
高贵花;
颜涛玲;
兰天舒

Publication type:

Article

Establishment and biological characterization of radioresistant colorectal cancer cell lines.

Published in:

FEBS Open Bio, 2025, v. 15, n. 6, p. 1009, doi. 10.1002/2211-5463.70016

By:

Qu, Tian‐Yin;
Dai, Qing;
Leng, Jing;
Fang, Lin;
Ma, Jing‐Jing;
Chen, Rui;
Chen, Che;
Ran, Peng‐Fei;
Zhou, Wen‐Wen;
Liu, Chang;
Yu, Huang‐Fei

Publication type:

Article

Exploring Mono and Bis‐gold(I)‐DTC Complexes Against Cancer and Leishmania.

Published in:

Chemistry - An Asian Journal, 2025, v. 20, n. 10, p. 1, doi. 10.1002/asia.202401553

By:

Soares dos Santos, Thaiz Cristina;
Salvador Tessaro, Patrícia;
de Andrade Querino, Ana Luiza;
Rodrigues Neto, Arthur Henrique;
Evangelista, Igor Martins Felix;
de Sousa, Alessandra Mara;
Nunes Rugani, Jerônimo;
Xerxes Coelho Oliveira, Willian;
Lima do Monte‐Neto, Rubens;
Silva, Heveline

Publication type:

Article

Expression of Platelet-Derived Growth Factor Alpha and Beta Receptors in Primary Tumor Cells of Patients with Renal Cell Carcinoma.

Published in:

Urology Research & Practice, 2025, v. 51, n. 1, p. 7, doi. 10.5152/tud.2025.24154

By:

Volkova, Maria;
Khochenkov, Dmitry;
Olshanskaya, Anna;
Khochenkova, Yulia;
Solomko, Elyso;
Ashuba, Saida;
Tsimafeyeu, Ilya

Publication type:

Article

QSAR STUDY OF SUBSTITUTED N-CONTAINING HETERO CYCLES AS AN ANTI-CANCER AGENTS.

Published in:

Bulletin of Pure & Applied Sciences-Zoology, 2024, v. 43B, p. 1151

By:

Mulani, Saloni Fakroddin;
Bhosale, Sachin K.;
Shinde, Nirmala;
Haque, Mohd Ziyaul

Publication type:

Article

Recent development in fibrin nanoparticles (F-NPs) and in vitro study targeting of oral cancer.

Published in:

Natural Product Research, 2025, v. 39, n. 11, p. 3348, doi. 10.1080/14786419.2024.2368757

By:

Rethinam, Senthil

Publication type:

Article

Trichothecenes with cytotoxic activity and benzene derivatives with hypolipidemic activity from trichothecium sp.

Published in:

Natural Product Research, 2025, v. 39, n. 11, p. 3181, doi. 10.1080/14786419.2024.2332488

By:

Xing, Liang;
Guo, Yi-Fan;
Hao, Ke-Ran;
Wu, Yi-Ting;
Yang, An-An

Publication type:

Article

Profiling of two Lampranthus species using LC-ESI/MS with evidence of their hepatoprotective activity.

Published in:

Natural Product Research, 2025, v. 39, n. 11, p. 3086, doi. 10.1080/14786419.2024.2325591

By:

Gabr, Nagwan M.;
Mina, Suzan Adib;
El Awdan, Sally A.;
Asaad, Gihan F.;
Abdelgayed, Sherein S.;
Mounir, Rafik F.

Publication type:

Article

Three Biscoumarin Compounds from Daphne gemmata.

Published in:

Chemistry of Natural Compounds, 2025, v. 61, n. 3, p. 422, doi. 10.1007/s10600-025-04669-4

By:

Li, Lin;
Song, Fu-Qiang;
Tang, Li-Ping;
Yu, Ping-Jing;
Li, Xian

Publication type:

Article

LocRecNet: A Synergistic Framework for Table Localization and Rectification.

Published in:

Electronics (2079-9292), 2025, v. 14, n. 10, p. 1920, doi. 10.3390/electronics14101920

By:

Cai, Zefeng;
Feng, Jie;
Hou, Zhaokun;
Zhang, Haixiang;
Ma, Hanjie

Publication type:

Article

Correction: Gambelunghe et al. Redox-Sensitive Glyoxalase 1 Up-Regulation Is Crucial for Protecting Human Lung Cells from Gold Nanoparticles Toxicity. Antioxidants 2020, 9 , 697.

Published in:

2025

By:

Gambelunghe, Angela;
Giovagnoli, Stefano;
Di Michele, Alessandro;
Boncompagni, Simona;
Dell'Omo, Marco;
Leopold, Kerstin;
Iavicoli, Ivo;
Talesa, Vincenzo Nicola;
Antognelli, Cinzia

Publication type:

Correction Notice

Effect of Heat-Assisted and Ultrasound-Assisted Extraction Methods on the Phenolic Profile and Biological Activity of Thymus vulgaris L. Extracts.

Published in:

Antioxidants, 2025, v. 14, n. 5, p. 567, doi. 10.3390/antiox14050567

By:

Spréa, Rafael Mascoloti;
Caleja, Cristina;
Pereira, Eliana;
Carocho, Márcio;
Pinela, José;
Finimundy, Tiane C.;
Calhelha, Ricardo C.;
Kostić, Marina;
Soković, Marina;
Prieto, Miguel A.;
Amaral, Joana S.;
Barros, Lillian

Publication type:

Article

Downregulation of cGAS/STING expression in tumor cells by cancer-associated fibroblasts in colorectal cancer.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03924-6

By:

Kanoda, Ryo;
Nakajima, Shotaro;
Okayama, Hirokazu;
Kaneta, Akinao;
Chida, Shun;
Matsumoto, Takuro;
Saito, Katsuharu;
Kikuchi, Tomohiro;
Maruyama, Yuya;
Suzuki, Hiroya;
Mimura, Kosaku;
Saito, Motonobu;
Hanayama, Hiroyuki;
Sakamoto, Wataru;
Momma, Tomoyuki;
Saze, Zenichiro;
Kono, Koji

Publication type:

Article

Establishment and evaluation of an immortalized dzo kidney cell line.

Published in:

Scientific Reports, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41598-025-03997-3

By:

Liu, Wenkai;
Xu, Cong;
Wang, Jiamin;
Sun, Na;
Ma, Zhongren;
Zhao, Jin;
Chen, Jianguo;
Li, You;
Qiao, Zilin

Publication type:

Article

Active Substances from the Micro-Immunotherapy Medicine 2LMIREG Display Antioxidative Properties In Vitro in Two Colorectal Cancer Cell Lines.

Published in:

Life (2075-1729), 2025, v. 15, n. 5, p. 743, doi. 10.3390/life15050743

By:

Garcia-Sureda, Laura;
Jacques, Camille;
Pons, Daniel G.;
Sastre-Serra, Jorge;
Oliver, Jordi;
Floris, Ilaria

Publication type:

Article

Genomic and Phenotypic Characterization of CHO 4BGD Cells with Quad Knockout and Overexpression of Two Housekeeping Genes That Allow for Metabolic Selection and Extended Fed-Batch Culturing.

Published in:

Cells (2073-4409), 2025, v. 14, n. 10, p. 692, doi. 10.3390/cells14100692

By:

Orlova, Nadezhda Alexandrovna;
Sinegubova, Maria Valerievna;
Kolesov, Denis Eduardovich;
Khodak, Yulia Alexandrovna;
Tatarskiy, Victor Vyacheslavovich;
Vorobiev, Ivan Ivanovich

Publication type:

Article

PI3K/mTOR Signaling Pathway Dual Inhibition for the Management of Neuroinflammation: Novel Insights from In Vitro Models.

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 677, doi. 10.3390/biom15050677

By:

Ardizzone, Alessio;
Scuderi, Sarah Adriana;
Casili, Giovanna;
Basilotta, Rossella;
Esposito, Emanuela;
Lanza, Marika

Publication type:

Article

Biological Activities of Essential Oils and Hydrolates from Different Parts of Croatian Sea Fennel (Crithmum maritimum L.).

Published in:

Biomolecules (2218-273X), 2025, v. 15, n. 5, p. 666, doi. 10.3390/biom15050666

By:

Slišković, Livia;
Režić Mužinić, Nikolina;
Politeo, Olivera;
Brzović, Petra;
Tomaš, Josip;
Generalić Mekinić, Ivana;
Popović, Marijana

Publication type:

Article

Editor's Note to: "p53-Dependent and p53-Independent Induction of Insulin-Like Growth Factor Binding Protein-3 by Deoxyribonucleic Acid Damage and Hypoxia" Free.

Published in:: Journal of Clinical Endocrinology & Metabolism, 2025, v. 110, n. 6, p. e2105, doi. 10.1210/clinem/dgaf169
Publication type:: Article

Isolation and Characterization of L-Asparaginase-Producing Bacteria from the Arabian–Persian Gulf Region: First Report on Bacillus xiamenensis ASP-J1-4 as a Producer and Its Potential Application.

Published in:

Marine Drugs, 2025, v. 23, n. 5, p. 194, doi. 10.3390/md23050194

By:

Al-Harbi, Ghofran M.;
Kotb, Essam;
Almiman, Abeer A.;
Berekaa, Mahmoud M.;
Alhamad, Salwa;
Alahmady, Nada F.;
Aljafary, Meneerah A.;
Alqazlan, Nadiyah M.;
Alyami, Reem I.;
Alqarni, Joud M.;
Al-Suhaimi, Ebtesam Abdullah

Publication type:

Article

Bioassay-Guided Procedure Coupled with HR-ESIMS Dereplication for Isolation of Antiproliferative Bromo-Tyramine Derivative from Aplysina cauliformis.

Published in:

Marine Drugs, 2025, v. 23, n. 5, p. 187, doi. 10.3390/md23050187

By:

Esposito, Germana;
Ponticelli, Maria;
Milella, Luigi;
Lela, Ludovica;
Teta, Roberta;
Pawlik, Joseph R.;
Russo, Daniela;
Costantino, Valeria

Publication type:

Article

Chemically defined and xeno-free media enables the derivation of human extended pluripotent stem cell lines from discarded blastocysts with a high efficiency.

Published in:

Cell & Bioscience, 2025, v. 15, n. 1, p. 1, doi. 10.1186/s13578-025-01410-0

By:

Zhao, Zhuran;
Chen, Xi;
Wang, Shan;
Fu, Min;
Shen, Huan;
Li, Jiayu;
Xu, Jun;
Qin, Jiong;
Shi, Cheng

Publication type:

Article

In Vitro Antiviral Assays: A Review of Laboratory Methods.

Published in:

Assay & Drug Development Technologies, 2025, v. 23, n. 4, p. 165, doi. 10.1089/adt.2024.075

By:

Atampugbire, Gabriel;
Adomako, Eureka Emefa Ahadjie;
Quaye, Osbourne

Publication type:

Article

Process Intensification for Recombinant Marburg Virus Glycoprotein Production Using Drosophila S2 Cells.

Published in:

Engineering in Life Sciences, 2025, v. 25, n. 5, p. 1, doi. 10.1002/elsc.70022

By:

Göbel, Sven;
Mayerlen, Ludwig;
Eiser, Isabelle Yazel;
Fichtmueller, Lisa;
Clements, David;
Reichl, Udo;
Genzel, Yvonne;
Lehrer, AxelT.

Publication type:

Article

Determination of the Cytotoxicity, Antioxidant, and Anti‐Lymphoma Efficacies of Allium saralicum Green‐Mediated Silver Nanoparticles.

Published in:

Applied Organometallic Chemistry, 2025, v. 39, n. 6, p. 1, doi. 10.1002/aoc.70167

By:

Li, Jing;
Li, Yan;
Li, Xiaohong;
Zhang, Qianqian

Publication type:

Article

Green Formulation of Ag Nanoparticles by Scrophularia striata: Introducing a Navel Chemotherapeutic Drug for the Treatment of Head and Neck Cancers.

Published in:

Applied Organometallic Chemistry, 2025, v. 39, n. 6, p. 1, doi. 10.1002/aoc.70160

By:

Liu, Geng;
Min, Yiyang;
Zhang, Zhenxing;
Ying, Yukang;
Zhou, Liyuan;
Mou, Tingchen

Publication type:

Article

Investigation of the antitumoral activity of tarantula cubensis extract on human hepatocelular cancer cells.

Published in:

Experimental Biomedical Research, 2025, v. 8, n. 1, p. 14, doi. 10.30714/j-ebr.2024.230

By:

Kurtkulagı, Ozgur;
Catal, Oguz;
Karabork, Seyda Ozsoy;
Kara, Sinem;
Çetinkaya, Ayhan;
Şit, Mustafa;
Ozer, Bahri

Publication type:

Article

Gadobutrol Exerts a Cytogenotoxic Effect in SH-SY5Y Neuroblastoma Cells.

Published in:

European Journal of Therapeutics, 2025, v. 31, n. 2, p. 81, doi. 10.58600/eurjther2576

By:

Bilgin, Batuhan;
Husunet, Mehmet Tahir

Publication type:

Article

Synthesis and Evaluation of 4-[5-((4-hydroxybenzylidene) amino)-1,3,4-thiadiazol-2-yl] Phenol Compound Biological Activities.

Published in:

Iranian Journal of Medical Microbiology, 2025, v. 19, n. 1, p. 29, doi. 10.30699/ijmm.19.1.29

By:

Saeed, Ban M.;
Al-Jadaan, Shaker A. N.;
Abbas, Basil A.

Publication type:

Article

Identification and Characterization of Antiviral Activity of Synthetic Compounds Against Mayaro Virus.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 717, doi. 10.3390/ph18050717

By:

Andreolla, Ana Paula;
Koishi, Andrea Cristine;
Borges, Alessandra Abel;
Oliveira, Larissa Albuquerque de;
Oliveira, Viviane Guedes de;
Lima, Nerilson Marques;
Ávila, Eloah Pereira;
de Castro, Pedro Pôssa;
Amarante, Giovanni Wilson;
de Almeida, Mauro Vieira;
Bordignon, Juliano;
Duarte dos Santos, Claudia Nunes

Publication type:

Article

Establishment of Two Novel Ovarian Tumor Cell Lines with Characteristics of Mucinous Borderline Tumors or Dedifferentiated Carcinoma—Implications for Tumor Heterogeneity and the Complex Carcinogenesis of Mucinous Tumors.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1716, doi. 10.3390/cancers17101716

By:

Sohel, Hasibul Islam;
Zahan, Umme Farzana;
Kiyono, Tohru;
Ishikawa, Masako;
Razia, Sultana;
Kanno, Kosuke;
Yamashita, Hitomi;
Sonia, Shahataj Begum;
Nakayama, Kentaro;
Kyo, Satoru

Publication type:

Article

From Genes to Environment: Elucidating Pancreatic Carcinogenesis Through Genetically Engineered and Risk Factor-Integrated Mouse Models.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1676, doi. 10.3390/cancers17101676

By:

Yan, Bin;
Fritsche, Anne-Kristin;
Haußner, Erik;
Inamdar, Tanvi Vikrant;
Laumen, Helmut;
Boettcher, Michael;
Gericke, Martin;
Michl, Patrick;
Rosendahl, Jonas

Publication type:

Article

Clinical Features and Outcomes of Primary Cutaneous Peripheral T-Cell Lymphoma, Not Otherwise Specified, Treated with CHOP-Based Regimens.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1673, doi. 10.3390/cancers17101673

By:

Hu, Ge;
Song, Zheng;
Lv, Chao;
Sun, Yifei;
Zhang, Yidan;
Liu, Xia;
Han, Xue;
Li, Lanfang;
Qiu, Lihua;
Qian, Zhengzi;
Zhou, Shiyong;
Gong, Wenchen;
Meng, Bin;
He, Jin;
Wang, Xianhuo;
Zhang, Huilai

Publication type:

Article

Exosome Enveloped by Nano Lipid Particle a New Model for Signal Transducer and Activator of Transcription 3 Silencer Ribonucleic Acid Delivery System to a Glioblastoma Mice Model.

Published in:

Cancers, 2025, v. 17, n. 10, p. 1648, doi. 10.3390/cancers17101648

By:

Monfaredan, Amir;
Şen, Sena;
Hosseininasab, Alaviyehsadat;
Taştekin, Didem;
Fazli, Ghazaleh;
Bozbey, Hamza Uğur;
Yousefi, Nasrin;
Hocaoğlu, Merve;
Öncül, Mustafa Oral;
Özen, Rıdvan Seçkin

Publication type:

Article