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- Title
Localized Ca[sup2 ] uncaging reveals polarized distribution of Ca[sup2 ]-sensitive Ca[sup2 ] release sites: mechanism of unidirectional Ca[sup2 ] waves.
- Authors
Ashby, Michael C.; Craske, Madeleine; Myoung Kyu Park; Gerasimenko, Oleg V.; Burgoyne, Robert D.; Petersen, Ole H.; Tepikin, Alexei V.
- Abstract
Investigates the calcium[sup2 ]-induced calcium[sup2 ] release (CICR) sensitivity of different regions of intact pancreatic acinar cells. Demonstrations of CICR sensitivity in local uncaging of caged calcium[sup2 ]; Role of CICR in the generation of cytosolic calcium signals in cells; Properties of CICR.
- Subjects
CALCIUM; PANCREATIC acinar cells; CYTOSOL
- Publication
Journal of Cell Biology, 2002, Vol 158, Issue 2, p283
- ISSN
0021-9525
- Publication type
Academic Journal
- DOI
10.1083/jcb.200112025