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- Title
Mathematical Modeling of a Flat-Membrane-Controlled Release Device.
- Authors
RAMRAJ, RITESH; FARRELL, STEPHANIE; LONEY, NORMAN
- Abstract
The closed form solution to a mathematical model of a flat membrane device successfully predicts the release profile of benzoic acid. Physically, the device consists of a given concentration of benzoic acid in octanol (reservoir) bounded by a microporous flat film (Cellgard 2400) with water-filled pores. The prediction shows excellent agreement with the experimentally derived release profile (maximum difference < 10%). Predicted results are obtained from the use of the steady state plus the first term of the transient solution (infinite series) and with the use of the first nonzero eigenvalue.
- Subjects
MATHEMATICAL models; ARTIFICIAL membranes
- Publication
Separation Science & Technology, 1999, Vol 34, Issue 11, p2251
- ISSN
0149-6395
- Publication type
Academic Journal
- DOI
10.1081/SS-100100770