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Title

Enzymatic Phenotyping and Evolutionary Relatedness of Species Specific Cytochromes P450 17α.

Authors

Estabrook, Ronald; Gilip, Andre; Guryev, Oleg; Usanov, Sergey

Abstract

Examines the nucleotide sequence of the cDNAs of cytochromes P450. Role of the cytochromes in steroid hormone biosynthesis; Comparison of evolutionary relatedness of the molecules; Inclination of the amino acids on the surface of the molecules to evolutionary change.

Subjects

NUCLEOTIDE sequence; CIRCULAR DNA; CYTOCHROME P-450; STEROID hormones; BIOSYNTHESIS; AMINO acids

Publication

Endocrine Research, 2004, Vol 30, Issue 4, p715

ISSN

0743-5800

Publication type

Academic Journal

DOI

10.1081/ERC-200044012

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