Works matching DE "PROTEIN kinase B regulation"

Results: 51

Chromatin regulation at the intersection of estrogen receptor and PI3K pathways in breast cancer.

Published in:

2019

By:

Castel, Pau;
Toska, Eneda

Publication type:

Opinion

TRB3 reverses chemotherapy resistance and mediates crosstalk between endoplasmic reticulum stress and AKT signaling pathways in MHCC97H human hepatocellular carcinoma cells.

Published in:

Oncology Letters, 2018, v. 15, n. 1, p. 1343, doi. 10.3892/ol.2017.7361

By:

Li, Yang;
Zhu, Danxi;
Hou, Lidan;
Hu, Bin;
Xu, Min;
Meng, Xiangjun

Publication type:

Article

Assessment of PI3K/AKT/PTEN signaling pathway activity in colorectal cancer using quantum dot-conjugated antibodies.

Published in:

Oncology Letters, 2018, v. 15, n. 1, p. 1236, doi. 10.3892/ol.2017.7392

By:

Waniczek, Dariusz;
Śnietura, Mirosław;
Lorenc, Zbigniew;
Nowakowska-Zajdel, Ewa;
Muc-Wierzgoń, Małgorzata

Publication type:

Article

SUMOylation regulates AKT1 activity.

Published in:

Oncogene, 2015, v. 34, n. 11, p. 1442, doi. 10.1038/onc.2014.48

By:

de la Cruz-Herrera, C F;
Campagna, M;
Lang, V;
del Carmen González-Santamaría, J;
Marcos-Villar, L;
Rodríguez, M S;
Vidal, A;
Collado, M;
Rivas, C

Publication type:

Article

DRR regulates AKT activation to drive brain cancer invasion.

Published in:

Oncogene, 2014, v. 33, n. 41, p. 4952, doi. 10.1038/onc.2013.436

By:

Dudley, A;
Sater, M;
Le, P U;
Trinh, G;
Sadr, M S;
Bergeron, J;
Deleavey, G F;
Bedell, B;
Damha, M J;
Petrecca, K

Publication type:

Article

Resveratrol Protects PC12 Cells from High Glucose-Induced Neurotoxicity Via PI3K/Akt/FoxO3a Pathway.

Published in:

Cellular & Molecular Neurobiology, 2015, v. 35, n. 4, p. 513, doi. 10.1007/s10571-014-0147-5

By:

Liu, Mi-Hua;
Yuan, Cong;
He, Jun;
Tan, Tian-Ping;
Wu, Shao-Jian;
Fu, Hong-Yun;
Liu, Jun;
Yu, Shan;
Chen, Yu-Dan;
Le, Qun-Fang;
Tian, Wei;
Hu, Heng-Jing;
Zhang, Yuan;
Lin, Xiao-Long

Publication type:

Article

FOXO3a and ?-catenin co-localization: double trouble in colon cancer?

Published in:

Nature Medicine, 2012, v. 18, n. 6, p. 854, doi. 10.1038/nm.2799

By:

Yan, Yibing;
Lackner, Mark R

Publication type:

Article

Early transformative changes in normal ovarian surface epithelium induced by oxidative stress require Akt upregulation, DNA damage and epithelial–stromal interaction.

Published in:

Carcinogenesis, 2013, v. 34, n. 5, p. 1125, doi. 10.1093/carcin/bgt003

By:

King, Shelby M.;
Quartuccio, Suzanne M.;
Vanderhyden, Barbara C.;
Burdette, Joanna E.

Publication type:

Article

Akt Regulates IL-10 Mediated Suppression of TNF&agr;- Induced Cardiomyocyte Apoptosis by Upregulating Stat3 Phosphorylation.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025009

By:

Dhingra, Sanjiv;
Bagchi, Ashim K.;
Ludke, Ana L.;
Sharma, Anita K.;
Singal, Pawan K.

Publication type:

Article

CD44v6 Regulates Growth of Brain Tumor Stem Cells Partially through the AKT-Mediated Pathway.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0024217

By:

Jijiwa, Mayumi;
Demir, Habibe;
Gupta, Snehalata;
Leung, Crystal;
Joshi, Kaushal;
Orozco, Nicholas;
Huang, Tiffany;
Yildiz, Vedat O.;
Shibahara, Ichiyo;
de Jesus, Jason A.;
Yong, William H.;
Mischel, Paul S.;
Fernandez, Soledad;
Kornblum, Harley I.;
Nakano, Ichiro

Publication type:

Article

Akt (protein kinase B) isoform phosphorylation and signaling downstream of mTOR (mammalian target of rapamycin) in denervated atrophic and hypertrophic mouse skeletal muscle.

Published in:: Journal of Molecular Signaling, 2012, v. 7, n. 1, p. 7, doi. 10.1186/1750-2187-7-7
Publication type:: Article

SMN Protein Contributes to Skeletal Muscle Cell Maturation Via Caspase-3 and Akt Activation.

Published in:

In Vivo, 2020, v. 34, n. 6, p. 3247, doi. 10.21873/invivo.12161

By:

SHIORI ANDO;
MIRUTO TANAKA;
NAOKI CHINEN;
SHINSUKE NAKAMURA;
MASAMITSU SHIMAZAWA;
HIDEAKI HARA

Publication type:

Article

Knockdown of RWD domain containing 3 inhibits the malignant phenotypes of glioblastoma cells via inhibition of phosphoinositide 3-kinase/protein kinase B signaling.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 16, n. 1, p. 384, doi. 10.3892/etm.2018.6135

By:

Chen, Xiaofeng;
Kuang, Weiping;
Huang, Hongxing;
Li, Bo;
Zhu, Yong;
Zhou, Bin;
Yan, Lin

Publication type:

Article

Rutin inhibits coronary heart disease through ERK1/2 and Akt signaling in a porcine model.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 15, n. 1, p. 506, doi. 10.3892/etm.2017.5365

By:

Lv, Lin;
Yao, Yucai;
Zhao, Gang;
Zhu, Guiyue

Publication type:

Article

PI3-kinase/Akt Pathway-Regulated Membrane Insertion of Acid-Sensing Ion Channel 1a Underlies BDNF-Induced Pain Hypersensitivity.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 18, p. 6351, doi. 10.1523/JNEUROSCI.4479-11.2012

By:

Duan, Bo;
Di-Shi Liu;
Yu Huang;
Wei-Zheng Zeng;
Xiang Wang;
Hui Yu;
Zhu, Michael X.;
Zhe-Yu Chen;
Tian-Le Xu

Publication type:

Article

Periostin Contributes to Cisplatin Resistance in Human Non-Small Cell Lung Cancer A549 Cells via Activation of Stat3 and Akt and Upregulation of Survivin.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2016, v. 38, n. 5, p. 1199, doi. 10.1159/000443068

By:

Wenxia Hu;
Pule Jin;
Wei Liu

Publication type:

Article

Royal Jelly Prevents the Progression of Sarcopenia in Aged Mice In Vivo and In Vitro.

Published in:

Journals of Gerontology Series A: Biological Sciences & Medical Sciences, 2013, v. 68, n. 12, p. 1482, doi. 10.1093/gerona/glt041

By:

Niu, Kaijun;
Guo, Hui;
Guo, Yinting;
Ebihara, Satoru;
Asada, Masanori;
Ohrui, Takashi;
Furukawa, Katsutoshi;
Ichinose, Masakazu;
Yanai, Kazuhiko;
Kudo, Yukitsuka;
Arai, Hiroyuki;
Okazaki, Tatsuma;
Nagatomi, Ryoichi

Publication type:

Article

Mechanisms of Resveratrol-Induced Inhibition of Clonal Expansion and Terminal Adipogenic Differentiation in 3T3-L1 Preadipocytes.

Published in:

2013

By:

Mitterberger, Maria C;
Zwerschke, Werner

Publication type:

Journal Article

Molecular Basis for the Regulation of Transcriptional Coactivator p300 in Myogenic Differentiation.

Published in:

Scientific Reports, 2015, p. 13727, doi. 10.1038/srep13727

By:

Chen, Jihong;
Wang, Yingjian;
Hamed, Munerah;
Lacroix, Natascha;
Li, Qiao

Publication type:

Article

Fenugreek Seed Powder Nullified Aluminium Chloride Induced Memory Loss, Biochemical Changes, Aβ Burden and Apoptosis via Regulating Akt/GSK3β Signaling Pathway.

Published in:

PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0165955

By:

Prema, Asokan;
Thenmozhi, Arokiasamy Justin;
Manivasagam, Thamilarasan;
Essa, Musthafa Mohamed;
Akbar, Mohammed D.;
Akbar, Mohammed

Publication type:

Article

Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway.

Published in:

Journal of Biosciences, 2012, v. 37, n. 1, p. 91, doi. 10.1007/s12038-011-9172-4

By:

Wang, Di;
Chen, Jian;
Chen, Hui;
Duan, Zhi;
Xu, Qimei;
Wei, Meiyan;
Wang, Lianghua;
Zhong, Meizuo

Publication type:

Article

LAB-1 Targets PP1 and Restricts Aurora B Kinase upon Entrance into Meiosis to Promote Sister Chromatid Cohesion.

Published in:

PLoS Biology, 2012, v. 10, n. 8, p. 1, doi. 10.1371/journal.pbio.1001378

By:

Tzur, Yonatan B.;
De Carvalho, Carlos Egydio;
Nadarajan, Saravanapriah;
Van Bostelen, Ivo;
Gu, Yanjie;
Chu, Diana S.;
Cheeseman, Iain M.;
Colaiácovo, Monica P.

Publication type:

Article

Clozapine Acts as an Agonist at Serotonin 2A Receptors to Counter MK-801-Induced Behaviors through a βArrestin2-Independent Activation of Akt.

Published in:

Neuropsychopharmacology, 2014, v. 39, n. 8, p. 1902, doi. 10.1038/npp.2014.38

By:

Schmid, Cullen L;
Streicher, John M;
Meltzer, Herbert Y;
Bohn, Laura M

Publication type:

Article

Chronic low-dose radiation inhibits the cells death by cytotoxic high-dose radiation increasing the level of AKT and acinus proteins via NF-κB activation.

Published in:

International Journal of Radiation Biology, 2013, v. 89, n. 5, p. 371, doi. 10.3109/09553002.2013.754560

By:

Park, Hyung Sun;
Seong, Ki Moon;
Kim, Ji Young;
Kim, Cha Soon;
Yang, Kwang Hee;
Jin, Young-Woo;
Nam, Seon Young

Publication type:

Article

Histone deacetylase inhibitor prevents cell growth in Burkitt's lymphoma by regulating PI3K/Akt pathways and leads to upregulation of miR-143, miR-145, and miR-101.

Published in:

Annals of Hematology, 2014, v. 93, n. 6, p. 983, doi. 10.1007/s00277-014-2021-4

By:

Santos Ferreira, Ana;
Robaina, Marcela;
Rezende, Lídia;
Severino, Patricia;
Klumb, Claudete

Publication type:

Article

Synthetic Polypeptide Derived from Viral Macrophage Inflammatory Protein II Inhibit VEGF Production of Human Glioma U87 Cells through SDF-1a/CXCR4-Mediated AKT Signaling Pathway.

Published in:

Tropical Journal of Pharmaceutical Research, 2014, v. 13, n. 8, p. 1327, doi. 10.4314/tjpr.v13i8.18

By:

Bo Xu;
Peng Tian;
Gui-Jie An;
Sha Liu;
Xiu-Ying Li;
Han-Xiao Sun;
Jing-Gung Zhou;
Qing Ding;
Pi-Jin Wei

Publication type:

Article

PI3K/Akt and HIF-1 signaling pathway in hypoxia-ischemia.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 4, p. 3547, doi. 10.3892/mmr.2018.9375

By:

Zhang, Zhen;
Yao, Li;
Yang, Jinhua;
Wang, Zhenkang;
Du, Gang

Publication type:

Article

Downregulation of CUEDC2 prevents doxorubicin-induced cardiotoxicity in H9c2 cells.

Published in:

Molecular Medicine Reports, 2018, v. 18, n. 1, p. 855, doi. 10.3892/mmr.2018.9072

By:

Zhang, Xianpu;
Li, Jiaojiao;
Cheng, Yongbo;
Yi, Jianguang;
Liu, Xin;
Cheng, Wei

Publication type:

Article

Tunicamycin inhibits colon carcinoma growth and aggressiveness via modulation of the ERK-JNK-mediated AKT/mTOR signaling pathway.

Published in:

Molecular Medicine Reports, 2018, v. 17, n. 3, p. 4203, doi. 10.3892/mmr.2018.8444

By:

You, Shuping;
Li, Weihong;
Guan, Yun

Publication type:

Article

Panax Notoginseng Saponins attenuates sevoflurane‑induced nerve cell injury by modulating AKT signaling pathway.

Published in:

Molecular Medicine Reports, 2017, v. 16, n. 5, p. 7829, doi. 10.3892/mmr.2017.7519

By:

XU YANG;
CHEN HONG;
WANG YU;
WANG GUONIAN;
SUN YANG

Publication type:

Article

Involvement of microRNA-93, a new regulator of PTEN/Akt signaling pathway, in regulation of chemotherapeutic drug cisplatin chemosensitivity in ovarian cancer cells

Published in:

FEBS Letters, 2012, v. 586, n. 9, p. 1279, doi. 10.1016/j.febslet.2012.03.006

By:

Fu, Xin;
Tian, Jing;
Zhang, Lei;
Chen, Ying;
Hao, Quan

Publication type:

Article

Effects of resveratrol on the amelioration of insulin resistance in KKA<sup>y</sup> mice.

Published in:

Canadian Journal of Physiology & Pharmacology, 2012, v. 90, n. 2, p. 237, doi. 10.1139/Y11-123

By:

Sifan Chen;
Jinghua Li;
Zili Zhang;
Wenxue Li;
Yanshuang Sun;
Quanxin Zhang;
Xiang Feng;
Wei Zhu

Publication type:

Article

Regulation of Akt and Wnt signaling by the group II metabotropic glutamate receptor antagonist LY341495 and agonist LY379268.

Published in:

Journal of Neurochemistry, 2011, v. 117, n. 6, p. 973, doi. 10.1111/j.1471-4159.2011.07268.x

By:

Sutton, Laurie P.;
Rushlow, Walter J.

Publication type:

Article

Perifosine induces protective autophagy and upregulation of ATG5 in human chronic myelogenous leukemia cells in vitro.

Published in:

Acta Pharmacologica Sinica, 2012, v. 33, n. 4, p. 542, doi. 10.1038/aps.2011.192

By:

Tong, Yin;
Liu, Yan-yan;
You, Liang-shun;
Qian, Wen-bin

Publication type:

Article

Gambogic acid inhibits TNF-α-induced invasion of human prostate cancer PC3 cells in vitro through PI3K/Akt and NF-κB signaling pathways.

Published in:

Acta Pharmacologica Sinica, 2012, v. 33, n. 4, p. 531, doi. 10.1038/aps.2011.180

By:

Lü, Lei;
Tang, Dong;
Wang, Liang;
Huang, Lu-qi;
Jiang, Guo-song;
Xiao, Xing-yuan;
Zeng, Fu-qing

Publication type:

Article

The sprout inhibitor 1,4-dimethylnaphthalene induces the expression of the cell cycle inhibitors KRP1 and KRP2 in potatoes.

Published in:

Functional & Integrative Genomics, 2012, v. 12, n. 3, p. 533, doi. 10.1007/s10142-011-0257-9

By:

Campbell, Michael;
Gleichsner, Alyssa;
Hilldorfer, Lindsay;
Horvath, David;
Suttle, Jeffrey

Publication type:

Article

Curcumin inhibits placental inflammation to ameliorate LPS-induced adverse pregnancy outcomes in mice via upregulation of phosphorylated Akt.

Published in:

Inflammation Research, 2017, v. 66, n. 2, p. 177, doi. 10.1007/s00011-016-1004-4

By:

Zhou, Jianjun;
Miao, Huishuang;
Li, Xiujun;
Hu, Yali;
Sun, Haixiang;
Hou, Yayi

Publication type:

Article

Computational Modelling of the Metabolic States Regulated by the Kinase Akt.

Published in:

Frontiers in Physiology, 2012, v. 3, p. 1, doi. 10.3389/fphys.2012.00418

By:

Mosca, Ettore;
Alfieri, Roberta;
Maj, Carlo;
Bevilacqua, Annamaria;
Canti, Gianfranco;
Milanesi, Luciano

Publication type:

Article

Estrogen regulates protein synthesis and actin polymerization in hippocampal neurons through different molecular mechanisms.

Published in:

Frontiers in Endocrinology, 2014, v. 5, p. 1, doi. 10.3389/fendo.2014.00022

By:

Briz, Victor;
Baudry, Michel

Publication type:

Article

Is TCL1 overexpression a good or a bad player in mantle cell lymphoma?

Published in:

2015

By:

Bea, Silvia;
Matutes, Estella

Publication type:

Editorial

Schistosoma japonicum Soluble Egg Antigens Facilitate Hepatic Stellate Cell Apoptosis by Downregulating Akt Expression and Upregulating p53 and DR5 Expression.

Published in:

PLoS Neglected Tropical Diseases, 2014, v. 8, n. 8, p. 1, doi. 10.1371/journal.pntd.0003106

By:

Wang, Jianxin;
Xu, Feifan;
Zhu, Dandan;
Duan, Yinong;
Chen, Jinling;
Sun, Xiaolei;
He, Xue;
Li, Pan;
Sun, Wei;
Feng, Jinrong

Publication type:

Article

PknB remains an essential and a conserved target for drug development in susceptible and MDR strains of M. Tuberculosis.

Published in:

Annals of Clinical Microbiology & Antimicrobials, 2017, v. 16, n. 1, p. 1, doi. 10.1186/s12941-017-0234-9

By:

Gupta, Anamika;
Pal, Sudhir;
Pandey, Divya;
Fakir, Najneen;
Rathod, Sunita;
Sinha, Dhiraj;
SivaKumar, S.;
Sinha, Pallavi;
Periera, Mycal;
Balgam, Shilpa;
Sekar, Gomathi;
UmaDevi, K.;
Anupurba, Shampa;
Nema, Vijay

Publication type:

Article

AKT-ing out: SGK kinases come to the fore.

Published in:

Biochemical Journal, 2013, v. 452, n. 3, p. 11, doi. 10.1042/BJ20130617

By:

MONIZ, Larissa S.;
VANHAESEBROECK, Bart

Publication type:

Article

Elevated SGK1 predicts resistance of breast cancer cells to Akt inhibitors.

Published in:

Biochemical Journal, 2013, v. 452, n. 3, p. 499, doi. 10.1042/BJ20130342

By:

SOMMER, Eeva M.;
DRY, Hannah;
CROSS, Darren;
GUICHARD, Sylvie;
DAVIES, Barry R.;
ALESSI, Dario R.

Publication type:

Article

MEG3 promotes liver cancer by activating PI3K/AKT pathway through regulating AP1G1.

Published in:

European Review for Medical & Pharmacological Sciences, 2019, v. 23, n. 4, p. 1459

By:

SUN, Y.;
CAO, F.-L.;
QU, L.-L.;
WANG, Z.-M.;
LIU, X.-Y.

Publication type:

Article

MicroRNA-150 enhances radiosensitivity by inhibiting the AKT pathway in NK/T cell lymphoma.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2018, v. 37, p. 1, doi. 10.1186/s13046-017-0639-5

By:

Wu, Shao Jie;
Chen, Jun;
Wu, BingYi;
Wang, Yu Jue;
Guo, Kun Yuan

Publication type:

Article

CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation.

Published in:

Cell Research, 2014, v. 24, n. 6, p. 742, doi. 10.1038/cr.2014.53

By:

Zhang, Luo;
Wang, Yiwu;
Xiao, Fengjun;
Wang, Shaoxia;
Xing, Guichun;
Li, Yang;
Yin, Xiushan;
Lu, Kefeng;
Wei, Rongfei;
Fan, Jiao;
Chen, Yuhan;
Li, Tao;
Xie, Ping;
Yuan, Lin;
Song, Lei;
Ma, Lanzhi;
Ding, Lujing;
He, Fuchu;
Zhang, Lingqiang

Publication type:

Article

USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-? type I receptor.

Published in:

Nature Cell Biology, 2012, v. 14, n. 7, p. 717, doi. 10.1038/ncb2522

By:

Zhang, Long;
Zhou, FangFang;
Drabsch, Yvette;
Gao, Rui;
Snaar-Jagalska, B. Ewa;
Mickanin, Craig;
Huang, Huizhe;
Sheppard, Kelly-Ann;
Porter, Jeff A.;
Lu, Chris X.;
ten Dijke, Peter

Publication type:

Article

Probiotics decrease depressive behaviors induced by constipation via activating the AKT signaling pathway.

Published in:

Metabolic Brain Disease, 2018, v. 33, n. 5, p. 1625, doi. 10.1007/s11011-018-0269-4

By:

Xu, Nana;
Fan, Wenting;
Zhou, Xiaoyan;
Liu, Yaping;
Ma, Ping;
Qi, Suhua;
Gu, Bing

Publication type:

Article

A parallel-arm phase I trial of the humanised anti-IGF-1R antibody dalotuzumab in combination with the AKT inhibitor MK-2206, the mTOR inhibitor ridaforolimus, or the NOTCH inhibitor MK-0752, in patients with advanced solid tumours.

Published in:

British Journal of Cancer, 2014, v. 111, n. 10, p. 1932, doi. 10.1038/bjc.2014.497

By:

Brana, I;
Siu, L L;
Almhanna, K;
Wenham, R M;
Gray, J E;
Sullivan, D M;
Dalton, W S;
Berger, R;
Golan, T;
Haluska, P;
Edenfield, J;
Stephenson, J;
Fiorica, J;
Martin, L P;
Westin, S;
Hanjani, P;
Jones, M B;
Gunchenko, A;
Cheng, J D

Publication type:

Article