Works matching DE "ADENOSINE diphosphate ribose"

Results: 182

Expanding the functional repertoire of macrodomains.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 407, doi. 10.1038/nsmb.2552

By:

Gamble, Matthew J

Publication type:

Article

The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 7, p. 685, doi. 10.1038/nsmb.2335

By:

Ali, Ammar A E;
Timinszky, Gyula;
Arribas-Bosacoma, Raquel;
Kozlowski, Marek;
Hassa, Paul O;
Hassler, Markus;
Ladurner, Andreas G;
Pearl, Laurence H;
Oliver, Antony W

Publication type:

Article

Structure of mammalian poly(ADP-ribose) glycohydrolase reveals a flexible tyrosine clasp as a substrate-binding element.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 6, p. 653, doi. 10.1038/nsmb.2305

By:

Kim, In-Kwon;
Kiefer, James R;
Ho, Chris M W;
Stegeman, Roderick A;
Classen, Scott;
Tainer, John A;
Ellenberger, Tom

Publication type:

Article

Synthesis of Well-Defined Adenosine Diphosphate Ribose Oligomers.

Published in:

Angewandte Chemie, 2015, v. 127, n. 16, p. 4997, doi. 10.1002/ange.201412283

By:

Kistemaker, Hans A. V.;
Lameijer, Lucien N.;
Meeuwenoord, Nico J.;
Overkleeft, Herman S.;
van der Marel, Gijsbert A.;
Filippov, Dmitri V.

Publication type:

Article

NAD-catabolizing ectoenzymes of Schistosoma mansoni.

Published in:

Biochemical Journal, 2022, v. 479, n. 11, p. 1165, doi. 10.1042/BCJ20210784

By:

Nation, Catherine S.;
Da'Dara, Akram A.;
Skelly, Patrick J.

Publication type:

Article

Outcomes in Clinically Relevant Patient Subgroups From the EMBRACA Study: Talazoparib vs Physician's Choice Standard-of-Care Chemotherapy.

Published in:

JNCI Cancer Spectrum, 2020, v. 4, n. 1, p. N.PAG, doi. 10.1093/jncics/pkz085

By:

Rugo, Hope S;
Ettl, Johannes;
Hurvitz, Sara A;
Gonçalves, Anthony;
Lee, Kyung-Hun;
Fehrenbacher, Louis;
Mina, Lida A;
Diab, Sami;
Woodward, Natasha E;
Yerushalmi, Rinat;
Goodwin, Annabel;
Blum, Joanne L;
Martin, Miguel;
Quek, Ruben G W;
Tudor, Iulia Cristina;
Bhattacharyya, Helen;
Gauthier, Eric;
Litton, Jennifer K;
Eiermann, Wolfgang

Publication type:

Article

Wheat SIMILAR TO RCD-ONE Gene Enhances Seedling Growth and Abiotic Stress Resistance by Modulating Redox Homeostasis and Maintaining Genomic Integrity.

Published in:

Plant Cell, 2014, v. 26, n. 1, p. 164, doi. 10.1105/tpc.113.118687

By:

Liu, Shuantao;
Liu, Shuwei;
Wang, Mei;
Wei, Tiandi;
Meng, Chen;
Wang, Meng;
Xia, Guangmin

Publication type:

Article

Abscisic Acid–Responsive Guard Cell Metabolomes of Arabidopsis Wild-Type and gpa1 G-Protein Mutants.

Published in:

Plant Cell, 2013, v. 25, n. 12, p. 4789, doi. 10.1105/tpc.113.119800

By:

Jin, Xiaofen;
Wang, Rui-Sheng;
Zhu, Mengmeng;
Jeon, Byeong Wook;
Albert, Reka;
Chen, Sixue;
Assmann, Sarah M.

Publication type:

Article

Skin metastasis from ovarian cancer with somatic BRCA1 mutation: A case report and literature review.

Published in:

2024

By:

Zhang, Jingheng;
He, Wenfeng;
Zhang, Zhenhua;
Dong, Hui;
Deng, Xiangyu;
Wen, Qinglian;
Li, Dan

Publication type:

Case Study

Transporter‑mediated drug‑drug interactions involving poly (ADP‑ribose) polymerase inhibitors (Review).

Published in:

Oncology Letters, 2023, v. 25, n. 4, p. N.PAG, doi. 10.3892/ol.2023.13747

By:

Zhao, Dehua;
Long, Xiaoqing;
Wang, Jisheng

Publication type:

Article

Atorvastatin potentiates the chemosensitivity of human liver cancer cells to cisplatin via downregulating YAP1.

Published in:

Oncology Letters, 2021, v. 21, n. 2, p. 1, doi. 10.3892/ol.2020.12343

By:

LIWEN GUO;
JIAPING ZHENG;
HUI ZENG;
ZHEWEI ZHANG;
GUOLIANG SHAO

Publication type:

Article

PARP9 is overexpressed in human breast cancer and promotes cancer cell migration.

Published in:

Oncology Letters, 2018, v. 16, n. 3, p. 4073, doi. 10.3892/ol.2018.9124

By:

Tang, Xinghong;
Zhang, Hongying;
Long, Yan;
Hua, Hui;
Jiang, Yangfu;
Jing, Jing

Publication type:

Article

Triptolide induces DNA breaks, activates caspase-3-dependent apoptosis and sensitizes B-cell lymphoma to poly(ADP-ribose) polymerase 1 and phosphoinositide 3-kinase inhibitors.

Published in:

Oncology Letters, 2017, v. 14, n. 4, p. 4965, doi. 10.3892/ol.2017.6771

By:

JIAWEI GUAN;
QIAN ZHAO;
JIAN LV;
ZHIWEI ZHANG;
SHIJIE SUN;
WEIFENG MAO

Publication type:

Article

Correlation between BRCA1 expression and the advanced stage of triple‑negative breast cancer.

Published in:

Molecular & Clinical Oncology, 2025, v. 22, n. 4, p. N.PAG, doi. 10.3892/mco.2025.2827

By:

Irianiwati, Irianiwati;
Gurky, Thela Calcarina;
Anwar, Sumadi Lukman;
Bawono, Rheza Gandi;
Dwianingsih, Ery Kus

Publication type:

Article

Inward currents and increases in cytosolic Ca2+ concentration induced by cyclic ADP-ribose in turtle olfactory receptor cells.

Published in:

Chemical Senses, 2003, v. 28, n. 5, p. 415, doi. 10.1093/chemse/28.5.415

By:

Sekimoto, Kousuke;
Kashiwayanagi, Makoto

Publication type:

Article

The PARP Way to Epigenetic Changes.

Published in:

Genes, 2021, v. 12, n. 3, p. 446, doi. 10.3390/genes12030446

By:

Ummarino, Simone;
Hausman, Clinton;
Di Ruscio, Annalisa;
Piunti, Andrea

Publication type:

Article

Rethinking cholera pathogenesis- No longer all in the same "camp".

Published in:

2016

By:

Barrett, Kim E.

Publication type:

Editorial

Effect of SP600125 on the mitotic spindle in HeLa Cells, leading to mitotic arrest, endoreduplication and apoptosis.

Published in:

Molecular Cytogenetics (17558166), 2016, v. 9, p. 1, doi. 10.1186/s13039-016-0296-y

By:

Mili, Donia;
Abid, Kaoutha;
Rjiba, Imed;
Kenani, Abderraouf

Publication type:

Article

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons.

Published in:: Molecular Brain, 2012, v. 5, n. 1, p. 11, doi. 10.1186/1756-6606-5-11
Publication type:: Article

Kinetic and mutational studies of the adenosine diphosphate ribose hydrolase from Mycobacterium tuberculosis.

Published in:

Journal of Bioenergetics & Biomembranes, 2016, v. 48, n. 6, p. 557, doi. 10.1007/s10863-016-9681-9

By:

O'Handley, Suzanne;
Thirawatananond, Puchong;
Kang, Lin-Woo;
Cunningham, Jennifer;
Leyva, J.;
Amzel, L.;
Gabelli, Sandra

Publication type:

Article

Cyclic ADP-ribose as an endogenous inhibitor of the mTOR pathway downstream of dopamine receptors in the mouse striatum.

Published in:

Journal of Neural Transmission, 2018, v. 125, n. 1, p. 17, doi. 10.1007/s00702-016-1666-7

By:

Higashida, Haruhiro;
Kamimura, Shin-ya;
Inoue, Takeshi;
Hori, Osamu;
Islam, Mohammad Saharul;
Lopatina, Olga;
Tsuji, Chiharu

Publication type:

Article

Oxidized Phosphatidylcholines Trigger TRPA1 and Ryanodine Receptor-dependent Airway Smooth Muscle Contraction.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2023, v. 69, n. 6, p. 649, doi. 10.1165/rcmb.2022-0457OC

By:

Vaghasiya, Jignesh;
Dalvand, Azadeh;
Sikarwar, Anurag;
Mangat, Divleen;
Ragheb, Mirna;
Kowatsch, Katarina;
Pandey, Dheerendra;
Hosseini, Seyed Mojtaba;
Hackett, Tillie L.;
Karimi-Abdolrezaee, Soheila;
Ravandi, Amir;
Pascoe, Christopher D.;
Halayko, Andrew J.

Publication type:

Article

Core-Scaffold-Inspired Asymmetric Synthesis of Polysubstituted Chiral Hexahydropyridazines that Potently Inhibit Breast Cancer Cell Proliferation by Inducing Apoptosis.

Published in:

Chemistry - A European Journal, 2015, v. 21, n. 50, p. 18100, doi. 10.1002/chem.201503063

By:

Leng, Hai ‐ Jun;
Peng, Fu;
Zingales, Sarah;
Huang, Wei;
Wang, Biao;
Zhao, Qian;
Zhou, Rui;
He, Gu;
Peng, Cheng;
Han, Bo

Publication type:

Article

Genome-scale CRISPR knockout screen identifies TIGAR as a modifier of PARP inhibitor sensitivity.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0580-6

By:

Fang, Pingping;
De Souza, Cristabelle;
Minn, Kay;
Chien, Jeremy

Publication type:

Article

Germline and somatic genetic testing in ovarian cancer patients.

Published in:

2018

By:

Chandrasekaran, D.;
Manchanda, R.

Publication type:

journal article

Population-based testing of non-mucinous epithelial ovarian cancer in Scotland.

Published in:

2018

By:

Evans, D. G.;
Edmondson, R.;
Crosbie, E. J.

Publication type:

journal article

细胞之间线粒体转移的主要途径、主要作用及主要调控机制.

Published in:

Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu, 2025, v. 29, n. 25, p. 5443, doi. 10.12307/2025.515

By:

李兴福;
周光前;
陆伟

Publication type:

Article

Poly(ADP-ribose): An organizer of cellular architecture.

Published in:

Journal of Cell Biology, 2014, v. 205, n. 5, p. 613, doi. 10.1083/jcb.201402114

By:

Leung, Anthony K. L.

Publication type:

Article

PARP inhibition selectively increases sensitivity to cisplatin in ERCC1-low non-small cell lung cancer cells.

Published in:

Carcinogenesis, 2013, v. 34, n. 4, p. 739, doi. 10.1093/carcin/bgs393

By:

Cheng, Haiying;
Zhang, Zhenfeng;
Borczuk, Alain;
Powell, Charles A.;
Balajee, Adayabalam S.;
Lieberman, Howard B.;
Halmos, Balazs

Publication type:

Article

PARPs and the DNA damage response.

Published in:

Carcinogenesis, 2012, v. 33, n. 8, p. 1433, doi. 10.1093/carcin/bgs132

By:

Sousa, Fabricio G.;
Matuo, Renata;
Soares, Daniele G.;
Escargueil, Alexandre E.;
Henriques, João A.P.;
Larsen, Annette K.;
Saffi, Jenifer

Publication type:

Article

Cisplatin induces primary necrosis through poly(ADP-ribose) polymerase 1 activation in kidney proximal tubular cells.

Published in:

Anatomy & Cell Biology, 2015, v. 48, n. 1, p. 66, doi. 10.5115/acb.2015.48.1.66

By:

Seulgee Park;
Sang Pil Yoon;
Jinu Kim

Publication type:

Article

Structural Requirements of Some 2-(1-Propylpiperidin-4-yl)-1H-benzimidazole-4-carboxamide Derivatives as Poly (ADP-Ribose) Polymerase (PARP) for the Treatment of Cancer: QSAR Approach.

Published in:

Interdisciplinary Sciences: Computational Life Sciences, 2016, v. 8, n. 1, p. 11, doi. 10.1007/s12539-015-0015-0

By:

Sharma, Mukesh

Publication type:

Article

Arginine Thiazolidine Carboxylate Stimulates Insulin Secretion through Production of Ca2+-Mobilizing Second Messengers NAADP and cADPR in Pancreatic Islets.

Published in:

PLoS ONE, 2015, v. 10, n. 8, p. 1, doi. 10.1371/journal.pone.0134962

By:

Park, Dae-Ryoung;
Shawl, Asif Iqbal;
Ha, Tae-Geun;
Park, Kwang-Hyun;
Kim, Seon-Young;
Kim, Uh-Hyun

Publication type:

Article

Effect of MRE11 Loss on PARP-Inhibitor Sensitivity in Endometrial Cancer In Vitro.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0100041

By:

Koppensteiner, Romana;
Samartzis, Eleftherios P.;
Noske, Aurelia;
von Teichman, Adriana;
Dedes, Ioannis;
Gwerder, Myriam;
Imesch, Patrick;
Ikenberg, Kristian;
Moch, Holger;
Fink, Daniel;
Stucki, Manuel;
Dedes, Konstantin J.

Publication type:

Article

Analysis of Poly(ADP-Ribose) Polymerases in Arabidopsis Telomere Biology.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088872

By:

Boltz, Kara A.;
Jasti, Madhu;
Townley, Jennifer M.;
Shippen, Dorothy E.

Publication type:

Article

Telomere Length Modulation in Human Astroglial Brain Tumors

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064296

By:

La Torre, Domenico;
Conti, Alfredo;
Aguennouz, M′Hammed;
De Pasquale, Maria Grazia;
Romeo, Sara;
Angileri, Filippo Flavio;
Cardali, Salvatore;
Tomasello, Chiara;
Alafaci, Concetta;
Germanò, Antonino

Publication type:

Article

PARP Inhibition Sensitizes to Low Dose-Rate Radiation TMPRSS2-ERG Fusion Gene-Expressing and PTEN-Deficient Prostate Cancer Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060408

By:

Chatterjee, Payel;
Choudhary, Gaurav S.;
Sharma, Arishya;
Singh, Kamini;
Heston, Warren D.;
Ciezki, Jay;
Klein, Eric A.;
Almasan, Alexandru

Publication type:

Article

Reduced Estradiol-Induced Vasodilation and Poly-(ADP-Ribose) Polymerase (PARP) Activity in the Aortas of Rats with Experimental Polycystic Ovary Syndrome (PCOS).

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0055589

By:

Masszi, Gabriella;
Horvath, Eszter Maria;
Tarszabo, Robert;
Benko, Rita;
Novak, Agnes;
Buday, Anna;
Tokes, Anna-Maria;
Nadasy, Gyorgy L.;
Hamar, Peter;
Benyó, Zoltán;
Varbiro, Szabolcs

Publication type:

Article

New Approaches of PARP-1 Inhibitors in Human Lung Cancer Cells and Cancer Stem-Like Cells by Some Selected Anthraquinone-Derived Small Molecules.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056284

By:

Lee, Yu-Ru;
Yu, Dah-Shyong;
Liang, Ya-Chun;
Huang, Kuo-Feng;
Chou, Shih-Jie;
Chen, Tsung-Chih;
Lee, Chia-Chung;
Chen, Chun-Liang;
Chiou, Shih-Hwa;
Huang, Hsu-Shan

Publication type:

Article

Clarifying the role of EMSY in DNA repair in ovarian cancer.

Published in:

2019

By:

Kondrashova, Olga;
Scott, Clare L.

Publication type:

journal article

Workshop encourages the clinical development of drug-radiotherapy combinations: Although medical oncology and radiation oncology have each evolved in exciting new ways, little has changed with regard to how they are used together. Leading organizations are taking aim at the issue.

Published in:

2019

By:

Printz, Carrie

Publication type:

journal article

A phase 2 study of the PARP inhibitor veliparib plus temozolomide in patients with heavily pretreated metastatic colorectal cancer.

Published in:

2018

By:

Pishvaian, Michael J.;
Slack, Rebecca S.;
Jiang, Wei;
He, A. Ruth;
Hwang, Jimmy J.;
Hankin, Amy;
Dorsch‐Vogel, Karen;
Kukadiya, Divyesh;
Weiner, Louis M.;
Marshall, John L.;
Brody, Jonathan R.;
Dorsch-Vogel, Karen

Publication type:

journal article

More breast cancer patients could benefit from PARP inhibitors.

Published in:: 2017
Publication type:: journal article

Exploiting DNA damage without repair: The activity of platinum chemotherapy in BRCA-mutated prostate cancers.

Published in:

2017

By:

Humeniuk, Michael S.;
Zhang, Tian;
Armstrong, Andrew J.

Publication type:

Editorial

Olaparib maintenance therapy in patients with platinum-sensitive, relapsed serous ovarian cancer and a BRCA mutation: Overall survival adjusted for postprogression poly(adenosine diphosphate ribose) polymerase inhibitor therapy.

Published in:

2016

By:

Matulonis, Ursula A.;
Harter, Philipp;
Gourley, Charlie;
Friedlander, Michael;
Vergote, Ignace;
Rustin, Gordon;
Scott, Clare;
Meier, Werner;
Shapira‐Frommer, Ronnie;
Safra, Tamar;
Matei, Daniela;
Fielding, Anitra;
Spencer, Stuart;
Parry, David;
Grinsted, Lynda;
Ledermann, Jonathan A.;
Shapira-Frommer, Ronnie

Publication type:

journal article

Contrasting sirtuin and poly( ADP-ribose)polymerase activities of selected 2,4,6-trisubstituted benzimidazoles.

Published in:

Chemical Biology & Drug Design, 2018, v. 91, n. 1, p. 213, doi. 10.1111/cbdd.13072

By:

Yeong, Keng Yoon;
Tan, Soo Choon;
Mai, Chun‐Wai;
Leong, Chee‐Onn;
Chung, Felicia Fei‐Lei;
Lee, Yean Kee;
Chee, Chin Fei;
Abdul Rahman, Noorsaadah

Publication type:

Article

Inhibition of poly (adenosine diphosphate-ribose) polymerase attenuates lung-kidney crosstalk induced by intratracheal lipopolysaccharide instillation in rats.

Published in:

Respiratory Research, 2013, v. 14, n. 11, p. 1, doi. 10.1186/1465-9921-14-126

By:

May Khin Hnin Si;
Chieko Mitaka;
Miniwan Tulafu;
Shinya Abe;
Masanobu Kitagawa;
Satoshi Ikeda;
Yoshinobu Eishi;
Shunichi Kurata;
Makoto Tomita

Publication type:

Article

CD38: A Potential Therapeutic Target in Cardiovascular Disease.

Published in:

Cardiovascular Drugs & Therapy, 2021, v. 35, n. 4, p. 815, doi. 10.1007/s10557-020-07007-8

By:

Zuo, Wanyun;
Liu, Na;
Zeng, Yunhong;
Liu, Yaozhong;
Li, Biao;
Wu, Keke;
Xiao, Yunbin;
Liu, Qiming

Publication type:

Article

Mechanistic insight into the role of Poly(ADP-ribosyl)ation in DNA topology modulation and response to DNA damage.

Published in:

Mutagenesis, 2020, v. 35, n. 1, p. 107, doi. 10.1093/mutage/gez045

By:

Matkarimov, Bakhyt T;
Zharkov, Dmitry O;
Saparbaev, Murat K

Publication type:

Article

LncRNA NEAT1/microRNA-124 regulates cell viability, inflammation and fibrosis in high-glucose-treated mesangial cells.

Published in:

Experimental & Therapeutic Medicine, 2022, v. 24, n. 2, p. N.PAG, doi. 10.3892/etm.2022.11434

By:

Zhao, Na;
Du, Likun;
Ma, Yingli;
Wang, Yang;
Ma, Jian;
Fang, Zhaohui

Publication type:

Article