We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Bioactive sesquiterpenes from an endophytic fungus Bipolaris sorokiniana isolated from a popular medicinal plant Costus speciosus.
- Authors
Qader, M. Mallique; Kumar, N. Savitri; Jayasinghe, Lalith; Araya, Hiroshi; Fujimoto, Yoshinori
- Abstract
Bipolaris sorokiniana, a fungal endophyte, was isolated from the leaves ofCostus speciosus, a popular medicinal plant used to control diabetes. Fermentation of the fungus in potato dextrose broth and chromatographic purification of the ethyl acetate (EtOAc) extracts of the culture broth and mycelium yielded two rare sesquiterpenes helminthosporal acid (1) and helminthosporol (2), together with ergosterol. Compounds1and2showed a strong phytotoxic effect on lettuce seed germination and toxicity against brine shrimps. Compound1also showed antifungal activity. Complete assignments of1H and13C NMR data of compound1are described for the first time.
- Subjects
SESQUITERPENES; COSTUS; HELMINTHOSPORIUM
- Publication
Mycology: An International Journal on Fungal Biology, 2017, Vol 8, Issue 1, p17
- ISSN
2150-1203
- Publication type
Academic Journal
- DOI
10.1080/21501203.2016.1269844