Employees who fail to balance work and life responsibilities are likely to experience job burnout and, ultimately, withdraw their engagement and voice in the workplace. The current study explored the relationships between employee burnout, work-family balance, and organizational dissent. More importantly, these relationships were tested in an under-researched and culturally unique context, Russia. Data collected from 232 full-time employees in the Perm region were analysed using multiple regression analysis. Analysis revealed that employee burnout is negatively related to articulated dissent and positively related to latent dissent. Furthermore, employees who receive managerial support for prioritizing family issues are less likely to experience job burnout. The influences of national culture and macroeconomic factors on the tested relationships are further discussed