Works matching DE "DRUG metabolism"

Results: 5000

Salidroside can protect against ferroptosis in cardiomyocytes and may be related to the regulation of GGT1.

Published in:

Frontiers in Pharmacology, 2025, p. 1, doi. 10.3389/fphar.2025.1580506

By:

Feng, Tianhang;
Shi, Jing;
Zhao, Jinghua;
Zhao, Qin;
Wang, Tao;
Wan, Sha;
Fan, Chen;
Wang, Sijia;
Lai, Chunyou;
Yao, Yutong

Publication type:

Article

Overexpression in Plasmodium falciparum of an intrinsically disordered protein segment of Pf UT impairs the parasite's proteostasis and reduces its growth rate.

Published in:

Frontiers in Cellular & Infection Microbiology, 2025, p. 1, doi. 10.3389/fcimb.2025.1565814

By:

Avalos-Padilla, Yunuen;
Bouzón-Arnáiz, Inés;
Ramírez, Miriam;
Camarero-Hoyos, Claudia;
Orozco-Quer, Marc;
M. Arce, Elsa;
Muñoz-Torrero, Diego;
Fernàndez-Busquets, Xavier

Publication type:

Article

Therapeutic drug monitoring, liquid biopsies or pharmacogenomics for prediction of human drug metabolism and response.

Published in:

British Journal of Clinical Pharmacology, 2025, v. 91, n. 6, p. 1569, doi. 10.1111/bcp.16048

By:

Ingelman‐Sundberg, Magnus;
Molden, Espen

Publication type:

Article

ADME Properties in Drug Delivery.

Published in:

Pharmaceutics, 2025, v. 17, n. 5, p. 617, doi. 10.3390/pharmaceutics17050617

By:

Scotti, Luciana;
Scotti, Marcus Tullius

Publication type:

Article

DPYD Genotyping, Fluoropyrimidine Dosage and Toxicity: An Umbrella Review of Systematic Reviews.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 727, doi. 10.3390/ph18050727

By:

Otero-Torres, Sara;
Rodríguez-Mauriz, Rosa;
Fort-Casamartina, Eduard;
Clopés-Estela, Ana;
Soler-Rotllant, Francesc;
Fontanals-Martínez, Sandra;
Montero-Pérez, Olalla

Publication type:

Article

Rapid screening system to identify unspecific peroxygenase activity.

Published in:

Clinical Hemorheology & Microcirculation, 2025, v. 89, n. 4, p. 363, doi. 10.1177/13860291241306566

By:

Schramm, Marina;
Carrillo Avilés, Carlos Renato;
Kalmbach, Johannes;
Schmidtke, Kai-Uwe;
Kiebist, Jan;
Kellner, Harald;
Hofrichter, Martin;
Scheibner, Katrin

Publication type:

Article

Pharmacokinetics of Antibiotics in Crocodiles: A Review.

Published in:

Animals (2076-2615), 2025, v. 15, n. 10, p. 1363, doi. 10.3390/ani15101363

By:

Laut, Seavchou;
Poapolathep, Saranya;
Sitthiangkool, Pandaree;
Klangkaew, Narumol;
Phaochoosak, Napasorn;
Giorgi, Mario;
Badillo, Elena;
Escudero, Elisa;
Marín, Pedro;
Poapolathep, Amnart

Publication type:

Article

Synergistic Effects of Epirubicin‐Vorinostat‐Pimozide Drug Cocktail on Proliferation, Stemness, Invasiveness, and Fatty Acid Metabolism in Breast Cancer Cells.

Published in:

IUBMB Life, 2025, v. 77, n. 5, p. 1, doi. 10.1002/iub.70020

By:

Kandasamy, Thirukumaran;
Sarkar, Shilpi;
Zochedh, Azar;
Kathiresan, Thandavarayan;
Ghosh, Siddhartha Sankar

Publication type:

Article

Fatal poisoning case involving drug interaction due to the inhibition of cytochrome P450.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2021, v. 78, n. 5, p. 563, doi. 10.2298/VSP170508090K

By:

Hiroshi Kinoshita;
Naoko Tanaka;
Mitsuru Kumihashi;
Mostofa Jamal;
Asuka Ito;
Tadayoshi Yamashita;
Kiyoshi Ameno

Publication type:

Article

Association of severity of depression, paroxetine use and markers of liver damage with QT interval duration in patients with alcohol dependence.

Published in:

Vojnosanitetski Pregled: Military Medical & Pharmaceutical Journal of Serbia, 2020, v. 77, n. 7, p. 680, doi. 10.2298/VSP180301120V

By:

Stojanović, Sanja Vukadinović;
Stojanović, Zlatan

Publication type:

Article

Tedaviye Dirençte İlaç Metabolizmasının Yeri ve Farmakogenetik Yaklaşım.

Published in:

Klinik Psikofarmakoloji Bulteni, 2009, v. 19, p. S54

By:

Yaflar, Ümit;
Babaoğlu, Melih Ö.

Publication type:

Article

The mechanistic classification of addictive drugs.

Published in:

2006

By:

Lüscher, Christian;
Ungless, Mark A

Publication type:

journal article

Photoredox‐Mediated Hydrogen Isotope Exchange Reactions of Amino‐Acids, Peptides, and Peptide‐Derived Drugs.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 56, p. 12738, doi. 10.1002/chem.202003464

By:

Legros, Fabien;
Fernandez‐Rodriguez, Patricia;
Mishra, Anurag;
Weck, Remo;
Bauer, Armin;
Sandvoss, Martin;
Ruf, Sven;
Méndez, María;
Mora‐Radó, Helena;
Rackelmann, Nils;
Pöverlein, Christoph;
Derdau, Volker

Publication type:

Article

N‐Aryl Amides as Chemical Exchange Saturation Transfer Magnetic Resonance Imaging Contrast Agents.

Published in:

Chemistry - A European Journal, 2020, v. 26, n. 51, p. 11705, doi. 10.1002/chem.202002415

By:

Cai, Xuekang;
Zhang, Jia;
Lu, Jiaqi;
Yi, Long;
Han, Zheng;
Zhang, Shuixing;
Yang, Xing;
Liu, Guanshu

Publication type:

Article

Cancer pharmacogenomics: achievements in basic research.

Published in:

International Journal of Clinical Oncology, 2005, v. 10, n. 1, p. 14, doi. 10.1007/s10147-004-0463-8

By:

Nakajima, Miki;
Yokoi, Tsuyoshi

Publication type:

Article

Cancer pharmacogenomics: international trends.

Published in:

International Journal of Clinical Oncology, 2005, v. 10, n. 1, p. 5, doi. 10.1007/s10147-004-0467-4

By:

Yamayoshi, Yasuko;
Iida, Emiko;
Tanigawara, Yusuke

Publication type:

Article

Cancer pharmacogenomics: progress and obstacles toward the goal.

Published in:

International Journal of Clinical Oncology, 2005, v. 10, n. 1, p. 3, doi. 10.1007/s10147-004-0462-9

By:

Nishiyama, Masahiko

Publication type:

Article

The A‐B‐C of small‐molecule ABC transport protein modulators: From inhibition to activation—a case study of multidrug resistance‐associated protein 1 (ABCC1).

Published in:

Medicinal Research Reviews, 2019, v. 39, n. 6, p. 2031, doi. 10.1002/med.21573

By:

Wiese, Michael;
Stefan, Sven Marcel

Publication type:

Article

Human Gut Microbiota and Drug Metabolism.

Published in:

Microbial Ecology, 2023, v. 86, n. 1, p. 97, doi. 10.1007/s00248-022-02081-x

By:

Pant, Archana;
Maiti, Tushar K.;
Mahajan, Dinesh;
Das, Bhabatosh

Publication type:

Article

Many tasks, but what is common for all of them?

Published in:

Journal of Solid State Electrochemistry, 2020, v. 24, n. 9, p. 2129, doi. 10.1007/s10008-020-04712-0

By:

Ludvík, Jiří

Publication type:

Article

Predicting drug pharmacokinetics and effect in vascularized tumors using computer simulation.

Published in:

Journal of Mathematical Biology, 2009, v. 58, n. 4/5, p. 485, doi. 10.1007/s00285-008-0214-y

By:

Sinek, John;
Sanga, Sandeep;
Zheng, Xiaoming;
Frieboes, Hermann;
Ferrari, Mauro;
Cristini, Vittorio

Publication type:

Article

Characterization of in vitro phase I metabolites of methamnetamine in human liver microsomes by liquid chromatography-quadrupole time-of-flight mass spectrometry.

Published in:

International Journal of Legal Medicine, 2021, v. 135, n. 4, p. 1471, doi. 10.1007/s00414-021-02594-z

By:

Hong, Young-ki;
Kim, Young-Hoon;
Lee, Jin-Moo;
Yoo, Hye Hyun;
Choi, Sun-Ok;
Kang, Mi Sun

Publication type:

Article

Studies on the phase I metabolism of the new designer drug 3-fluoromethcathinone using rabbit liver slices.

Published in:

International Journal of Legal Medicine, 2012, v. 126, n. 2, p. 231, doi. 10.1007/s00414-011-0601-6

By:

Pawlik, Evelyn;
Plässer, Gerd;
Mahler, Hellmut;
Daldrup, Thomas

Publication type:

Article

Separation of positional CPP isomers by chiral HPLC-DAD of seized tablets.

Published in:

International Journal of Legal Medicine, 2011, v. 125, n. 1, p. 95, doi. 10.1007/s00414-010-0422-z

By:

Schürenkamp, Jennifer;
Beike, Justus;
Pfeiffer, Heidi;
Köhler, Helga

Publication type:

Article

Influence of cigarette smoking on drugs' metabolism and effects: a systematic review.

Published in:

European Journal of Clinical Pharmacology, 2025, v. 81, n. 5, p. 667, doi. 10.1007/s00228-025-03817-7

By:

Zanni, Stefano;
Del Prete, Jole;
Capogrossi, Alessandra;
Papapietro, Giuseppe;
Del Cimmuto, Angela;
Gazzanelli, Sergio;
Caronna, Andrea;
Protano, Carmela

Publication type:

Article

Validating the accuracy of mathematical model–based pharmacogenomics dose prediction with real-world data.

Published in:

European Journal of Clinical Pharmacology, 2025, v. 81, n. 3, p. 451, doi. 10.1007/s00228-025-03805-x

By:

Saab, Yolande;
Nakad, Zahi

Publication type:

Article

Medication prescribing in frail older people.

Published in:

European Journal of Clinical Pharmacology, 2013, v. 69, n. 3, p. 319, doi. 10.1007/s00228-012-1387-2

By:

Hubbard, Ruth;
O'Mahony, M.;
Woodhouse, Kenneth

Publication type:

Article

Repeated administration of berberine inhibits cytochromes P450 in humans.

Published in:

European Journal of Clinical Pharmacology, 2012, v. 68, n. 2, p. 213, doi. 10.1007/s00228-011-1108-2

By:

Guo, Ying;
Chen, Yao;
Tan, Zhi-rong;
Klaassen, Curtis;
Zhou, Hong-hao

Publication type:

Article

Linkage disequilibrium between the CYP2C19*17 allele and wildtype CYP2C8 and CYP2C9 alleles: identification of CYP2C haplotypes in healthy Nordic populations.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 12, p. 1199, doi. 10.1007/s00228-010-0864-8

By:

Pedersen, Rasmus;
Brasch-Andersen, Charlotte;
Sim, Sarah;
Bergmann, Troels;
Halling, Jónrit;
Petersen, Maria;
Weihe, Pál;
Edvardsen, Hege;
Kristensen, Vessela;
Brøsen, Kim;
Ingelman-Sundberg, Magnus

Publication type:

Article

A systematic review of pharmacokinetics studies in children with protein-energy malnutrition.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 10, p. 1025, doi. 10.1007/s00228-010-0851-0

By:

Oshikoya, Kazeem;
Sammons, Helen;
Choonara, Imti

Publication type:

Article

Fluconazole-induced intoxication with phenytoin in a patient with ultra-high activity of CYP2C9.

Published in:

2010

By:

Helldén, Anders;
Bergman, Ulf;
Engström Hellgren, Karin;
Masquelier, Michèle;
Nilsson Remahl, Ingela;
Odar-Cederlöf, Ingegerd;
Ramsjö, Margareta;
Bertilsson, Leif

Publication type:

Case Study

Variability in drug metabolizing enzyme activity in HIV-infected patients.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 5, p. 475, doi. 10.1007/s00228-009-0777-6

By:

Jones, Amanda;
Brown, Kevin;
Werner, Rebecca;
Gotzkowsky, Karl;
Gaedigk, Andrea;
Blake, Mike;
Hein, David;
Horst, Charles;
Kashuba, Angela

Publication type:

Article

Carriers of the UGT1A4 142T>G gene variant are predisposed to reduced olanzapine exposure—an impact similar to male gender or smoking in schizophrenic patients.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 5, p. 465, doi. 10.1007/s00228-009-0783-8

By:

Ghotbi, Roza;
Mannheimer, Buster;
Aklillu, Eleni;
Suda, Akira;
Bertilsson, Leif;
Eliasson, Erik;
Ösby, Urban

Publication type:

Article

Effects of Ginkgo biloba extracts on diazepam metabolism: a pharmacokinetic study in healthy Chinese male subjects.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 5, p. 503, doi. 10.1007/s00228-010-0795-4

By:

Zuo, Xiao-Cong;
Zhang, Bi-Kui;
Jia, Su-Jie;
Liu, Shi-Kun;
Zhou, Ling-Yun;
Li, Jing;
Zhang, Jie;
Dai, Ling-Ling;
Chen, Ben-Mei;
Yang, Guo-Ping;
Yuan, Hong

Publication type:

Article

Pharmacokinetics of intravenous omeprazole in critically ill paediatric patients.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 4, p. 323, doi. 10.1007/s00228-009-0774-9

By:

Solana, Maria;
López-Herce, Jesús

Publication type:

Article

CYP3A activity influences imatinib response in patients with chronic myeloid leukemia: a pilot study on in vivo CYP3A activity.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 4, p. 383, doi. 10.1007/s00228-009-0772-y

By:

Gréen, Henrik;
Skoglund, Karin;
Rommel, Franz;
Mirghani, Rajaa;
Lotfi, Kourosh

Publication type:

Article

In vitro-in vivo extrapolation of zolpidem as a perpetrator of metabolic interactions involving CYP3A.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 3, p. 275, doi. 10.1007/s00228-009-0760-2

By:

Polasek, Thomas;
Sadagopal, Janani;
Elliot, David;
Miners, John

Publication type:

Article

Hepatic CYP2A6 levels and nicotine metabolism: impact of genetic, physiological, environmental, and epigenetic factors.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 3, p. 239, doi. 10.1007/s00228-009-0762-0

By:

Koudsi, Nael;
Hoffmann, Ewa;
Assadzadeh, Abbas;
Tyndale, Rachel

Publication type:

Article

Pharmacokinetic interaction between oral lovastatin and verapamil in healthy subjects: role of P-glycoprotein inhibition by lovastatin.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 3, p. 285, doi. 10.1007/s00228-009-0757-x

By:

Choi, Dong-Hyun;
Chung, Joong-Hwa;
Choi, Jun-Shik

Publication type:

Article

Is there any difference between acetylator phenotypes in tuberculosis patients and healthy subjects?

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 3, p. 261, doi. 10.1007/s00228-009-0745-1

By:

Khalili, Hossein;
Dashti-Khavidaki, Simin;
Amini, Mohsen;
Mahjub, Reza;
Hajiabdolbaghi, Mahboobeh

Publication type:

Article

Influence of the CYP2D6 polymorphism and hemodialysis on codeine disposition in patients with end-stage renal disease.

Published in:

European Journal of Clinical Pharmacology, 2010, v. 66, n. 3, p. 269, doi. 10.1007/s00228-009-0759-8

By:

Molanaei, Hadi;
Carrero, Juan;
Heimbürger, Olof;
Nordfors, Louise;
Lindholm, Bengt;
Stenvinkel, Peter;
Odar-Cederlöf, Ingegerd;
Bertilsson, Leif

Publication type:

Article

The development of an objective methodology to measure medication adherence to oral thiopurines in paediatric patients with acute lymphoblastic leukaemia—an exploratory study.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 11, p. 1105, doi. 10.1007/s00228-009-0700-1

By:

Hawwa, Ahmed F.;
Millership, Jeff S.;
Collier, Paul S.;
McCarthy, Anthony;
Dempsey, Sid;
Cairns, Carole;
McElnay, James C.

Publication type:

Article

Pharmacokinetics and dose requirements of factor VIII over the age range 3–74 years.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 10, p. 989, doi. 10.1007/s00228-009-0676-x

By:

Björkman, Sven;
Folkesson, Anna;
Jönsson, Siv

Publication type:

Article

Effect of ritonavir on the pharmacokinetics of the benzimidazoles albendazole and mebendazole: an interaction study in healthy volunteers.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 10, p. 999, doi. 10.1007/s00228-009-0683-y

By:

Corti, Natascia;
Heck, Antje;
Rentsch, Katharina;
Zingg, Walter;
Jetter, Alexander;
Stieger, Bruno;
Pauli-Magnus, Christiane

Publication type:

Article

Exploring warfarin pharmacogenomics with the extreme-discordant-phenotype methodology: impact of FVII polymorphisms on stable anticoagulation with warfarin.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 8, p. 789, doi. 10.1007/s00228-009-0651-6

By:

Fuchshuber-Moraes, Mateus;
Perini, Jamila A.;
Rosskopf, Dieter;
Suarez-Kurtz, Guilherme

Publication type:

Article

Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 8, p. 809, doi. 10.1007/s00228-009-0656-1

By:

Navaratnam, Visweswaran;
Ramanathan, Surash;
Wahab, Mohd Suhaimi Ab.;
Gan Siew Hua;
Mansor, Sharif Mahsufi;
Kiechel, Jean-René;
Vaillant, Michel;
Taylor, Walter R. J.;
Olliaro, Piero

Publication type:

Article

Pharmacokinetics and dosage adjustment in patients with renal dysfunction.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 8, p. 757, doi. 10.1007/s00228-009-0678-8

By:

Verbeeck, Roger K.;
Musuamba, Flora T.

Publication type:

Article

Pharmacokinetics and metabolism of idebenone in healthy male subjects.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 5, p. 493, doi. 10.1007/s00228-008-0596-1

By:

Bodmer, Michael;
Vankan, Pierre;
Dreier, Manfred;
Kutz, Klaus W.;
Drewe, Jürgen

Publication type:

Article

The CYP2C19 ultra-rapid metabolizer genotype influences the pharmacokinetics of voriconazole in healthy male volunteers.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 3, p. 281, doi. 10.1007/s00228-008-0574-7

By:

Guo Wang;
He-Ping Lei;
Zhi Li;
Zhi-Rong Tan;
Dong Guo;
Lan Fan;
Yao Chen;
Dong-Li Hu;
Dan Wang;
Hong-Hao Zhou

Publication type:

Article

Role of active metabolites in the use of opioids.

Published in:

European Journal of Clinical Pharmacology, 2009, v. 65, n. 2, p. 121, doi. 10.1007/s00228-008-0570-y

By:

Coller, Janet;
Christrup, Lona;
Somogyi, Andrew

Publication type:

Article