Works matching DE "ANTINEOPLASTIC agent synthesis"

Results: 137

Total Synthesis and Biological Evaluation of Jerantinine E.

Published in:

Angewandte Chemie, 2013, v. 125, n. 50, p. 13615, doi. 10.1002/ange.201305533

By:

Frei, Reto;
Staedler, Davide;
Raja, Aruna;
Franke, Raimo;
Sasse, Florenz;
Gerber ‐ Lemaire, Sandrine;
Waser, Jérôme

Publication type:

Article

Algorithm of Molecular and Biological Assessment of the Mechanisms of Sensitivity to Drug Toxicity by the Example of Cyclophosphamide.

Published in:

Bulletin of Experimental Biology & Medicine, 2018, v. 164, n. 3, p. 324, doi. 10.1007/s10517-018-3982-4

By:

Telegin, L.;
Sarmanaev, S.;
Devichenskii, V.;
Tutelyan, V.

Publication type:

Article

Synthesis and Anticancer evaluation of (-)-Arctigenin Derivatives.

Published in:

Journal of the Chemical Society of Pakistan, 2014, v. 36, n. 5, p. 870

By:

Yubin Xu;
Guirong Chen;
Deqiang Dou;
Hongshuai Jiang;
Tingguo Kang

Publication type:

Article

Synthesis and anticancer activity of novel quinazolinone and benzamide derivatives.

Published in:

Research on Chemical Intermediates, 2018, v. 44, n. 4, p. 2545, doi. 10.1007/s11164-017-3245-4

By:

El-Hashash, Maher Abd El-Aziz Mahmoud;
Salem, Marwa Sayed;
Al-Mabrook, Selima Ali Mohamed

Publication type:

Article

Synthesis and anticancer activities of 1,4-phenylene-bis- N-acetyl- and N-phenylpyrazoline derivatives.

Published in:

Research on Chemical Intermediates, 2017, v. 43, n. 3, p. 1277, doi. 10.1007/s11164-016-2697-2

By:

Gürdere, Meliha;
Gümüş, Onur;
Yaglioglu, Ayse;
Budak, Yakup;
Ceylan, Mustafa

Publication type:

Article

Synthesis, crystal structure and antitumor activity of a dinuclear calcium complex based on 1,5-naphthalenedisulfonate and 2,2′-bipyridine ligands.

Published in:

Research on Chemical Intermediates, 2015, v. 41, n. 7, p. 4339, doi. 10.1007/s11164-014-1533-9

By:

Tai, Xi-Shi;
Zhang, Yan-Ping;
Zhao, Wen-Hua

Publication type:

Article

Synthesis of some new pyrimidine derivatives and evaluation of their anticancer and antibacterial activities.

Published in:

Research on Chemical Intermediates, 2013, v. 39, n. 3, p. 821, doi. 10.1007/s11164-012-0597-7

By:

Fathalla, Omar;
Mohamed, Neama;
El-Serwy, Walaa;
AbdelHamid, Hala;
Abd El-Moez, Sherein;
Soliman, Abdel-mohsen

Publication type:

Article

Synthesis and biological evaluation of 2-(phenyl)-3H-benzo[d]imidazole-5-carboxylic acids and its methyl esters as potent anti-breast cancer agents.

Published in:

Arabian Journal of Chemistry, 2017, v. 10, p. S1788, doi. 10.1016/j.arabjc.2013.07.003

By:

Karthikeyan, Chandrabose;
Solomon, Viswas Raja;
Lee, Hoyun;
Trivedi, Piyush

Publication type:

Article

Localization of putative binding sites for cyclic guanosine monophosphate and the anti-cancer drug 5-fluoro-2'-deoxyuridine-5'-monophosphate on ABCC11 in silico models.

Published in:

BMC Structural Biology, 2013, v. 13, p. 1, doi. 10.1186/1472-6807-13-7

By:

Honorat, Mylène;
Terreux, Raphaël;
Falson, Pierre;
Di Pietro, Attilio;
Dumontet, Charles;
Payen, Lea

Publication type:

Article

Utilization of 2-Chloronicotinonitrile in the Syntheses of Novel Fused Bicyclic and Polynuclear Heterocycles of Anticipated Antitumor Activity.

Published in:

Journal of Heterocyclic Chemistry, 2016, v. 53, n. 3, p. 953, doi. 10.1002/jhet.1631

By:

Hamama, Wafaa S.;
Waly, Mohamed A.;
El ‐ Hawary, Ibrahim I.;
Zoorob, Hanafi H.

Publication type:

Article

Synthesis of Some New Benzimidazole-Thiazole Derivatives as Anticancer Agents.

Published in:

Journal of Heterocyclic Chemistry, 2014, v. 51, n. 6, p. 1797, doi. 10.1002/jhet.1886

By:

Nofal, Zienab M.;
Soliman, Elsyed A.;
Abd El ‐ Karim, Somaia S.;
El ‐ Zahar, Magdy I.;
Srour, Aladdin M.;
Sethumadhavan, Shalini;
Maher, Timothy J.

Publication type:

Article

Convenient Synthesis of Toxoflavin that Targets β-Catenin/Tcf4 Signaling Activities.

Published in:

Journal of Heterocyclic Chemistry, 2014, v. 51, n. 3, p. 594, doi. 10.1002/jhet.1111

By:

Mao, Yongjun;
Tian, Wang;
Huang, Ziwei;
An, Jing

Publication type:

Article

Synthesis and biological activities of the amide derivative of aplog-1, a simplified analog of aplysiatoxin with anti-proliferative and cytotoxic activities.

Published in:

Bioscience, Biotechnology & Biochemistry, 2015, v. 79, n. 6, p. 888, doi. 10.1080/09168451.2014.1002452

By:

Yusuke Hanaki;
Yanagita, Ryo C.;
Takahiro Sugahara;
Misako Aida;
Harukuni Tokuda;
Nobutaka Suzuki;
Kazuhiro Irie

Publication type:

Article

Synthesis and Cytotoxic Evaluation of Monocarbonyl Analogs of Curcumin as Potential Anti-Tumor Agents.

Published in:

Drug Development Research, 2016, v. 77, n. 1, p. 43, doi. 10.1002/ddr.21291

By:

Pan, Zheer;
Chen, Chengwei;
Zhou, Yeli;
Xu, Feng;
Xu, Yaozeng

Publication type:

Article

Design, Synthesis and Evaluation of Naphthalimide Derivatives as Potential Anticancer Agents for Hepatocellular Carcinoma.

Published in:

Molecules, 2017, v. 22, n. 2, p. 342, doi. 10.3390/molecules22020342

By:

Chaochao Ge;
Liping Chang;
Ying Zhao;
Congcong Chang;
Xiaojuan Xu;
Haoying He;
Yuxia Wang;
Fujun Dai;
Songqiang Xie;
Chaojie Wang

Publication type:

Article

Analysis of the Total Biflavonoids Extract from Selaginella doederleinii by HPLC-QTOF-MS and Its In Vitro and In Vivo Anticancer Effects.

Published in:

Molecules, 2017, v. 22, n. 2, p. 325, doi. 10.3390/molecules22020325

By:

Hong Yao;
Bing Chen;
Yanyan Zhang;
Huigen Ou;
Yuxiang Li;
Shaoguang Li;
Peiying Shi;
Xinhua Lin

Publication type:

Article

Synthesis and Biological Evaluation of Novel 8-Morpholinoimidazo[1,2-a]pyrazine Derivatives Bearing Phenylpyridine/Phenylpyrimidine-Carboxamides.

Published in:

Molecules, 2017, v. 22, n. 2, p. 310, doi. 10.3390/molecules22020310

By:

Shan Xu;
Chengyu Sun;
Chen Chen;
Pengwu Zheng;
Yong Zhou;
Hongying Zhou;
Wufu Zhu

Publication type:

Article

Synthesis, Anti-Breast Cancer Activity, and Molecular Docking Study of a New Group of Acetylenic Quinolinesulfonamide Derivatives.

Published in:

Molecules, 2017, v. 22, n. 2, p. 300, doi. 10.3390/molecules22020300

By:

Marciniec, Krzysztof;
Pawełczak, Bartosz;
Latocha, Małgorzata;
Skrzypek, Leszek;
Maciążek-Jurczyk, Małgorzata;
Boryczka, Stanisław

Publication type:

Article

Anticancer Activities of C18-, C19-, C20-, and Bis-Diterpenoid Alkaloids Derived from Genus Aconitum.

Published in:

Molecules, 2017, v. 22, n. 2, p. 267, doi. 10.3390/molecules22020267

By:

Meng-Yue Ren;
Qing-Tian Yu;
Chun-Yu Shi;
Jia-Bo Luo

Publication type:

Article

Flavonoid Composition and Antitumor Activity of Bee Bread Collected in Northeast Portugal.

Published in:

Molecules, 2017, v. 22, n. 2, p. 248, doi. 10.3390/molecules22020248

By:

Sobral, Filipa;
Calhelha, Ricardo C.;
Barros, Lillian;
Dueñas, Montserrat;
Tomás, Andreia;
Santos-Buelga, Celestino;
Vilas-Boas, Miguel;
Ferreira, Isabel C. F. R.

Publication type:

Article

Cearoin Induces Autophagy, ERK Activation and Apoptosis via ROS Generation in SH-SY5Y Neuroblastoma Cells.

Published in:

Molecules, 2017, v. 22, n. 2, p. 242, doi. 10.3390/molecules22020242

By:

Tonking Bastola;
Ren-bo An;
Youn-Chul Kim;
Jaehyo Kim;
Jungwon Seo

Publication type:

Article

Synthesis and Antitumor Activities of Chiral Dipeptide Thioureas Containing an Alpha-Aminophosphonate Moiety.

Published in:

Molecules, 2017, v. 22, n. 2, p. 238, doi. 10.3390/molecules22020238

By:

Jingzi Liu;
Peng Liao;
Junfeng Hu;
Hong Zhu;
Yonglin Wang;
Yongjun Li;
Yan Li;
Bin He

Publication type:

Article

Hinokitiol Exerts Anticancer Activity through Downregulation of MMPs 9/2 and Enhancement of Catalase and SOD Enzymes: In Vivo Augmentation of Lung Histoarchitecture.

Published in:

Molecules, 2015, v. 20, n. 10, p. 17720, doi. 10.3390/molecules201017720

By:

Chien-Hsun Huang;
Jayakumar, Thanasekaran;
Chao-Chien Chang;
Tsorng-Harn Fong;
Shing-Hwa Lu;
Aloysius Thomas, Philip;
Cheuk-Sing Choy;
Joen-Rong Sheu

Publication type:

Article

Microwave-Assisted Synthesis of Novel Pyrazolo[3,4-g][1,8]naphthyridin-5-amine with Potential Antifungal and Antitumor Activity.

Published in:

Molecules, 2015, v. 20, n. 5, p. 8499, doi. 10.3390/molecules20058499

By:

Acosta, Paola;
Butassi, Estefanía;
Insuasty, Braulio;
Ortiz, Alejandro;
Abonia, Rodrigo;
Zacchino, Susana A.;
Quiroga, Jairo

Publication type:

Article

Design, Synthesis, and Biological Evaluation of Artemisinin-Indoloquinoline Hybrids as Potent Antiproliferative Agents.

Published in:

Molecules, 2014, v. 19, n. 11, p. 19021, doi. 10.3390/molecules191119021

By:

Li Wang;
Świtalska, Marta;
Ning Wang;
Zhen-Jun Du;
Yuta Fukumoto;
Nguyen Kim Diep;
Ryo Kiguchi;
Junzo Nokami;
Wietrzyk, Joanna;
Tsutomu Inokuchi

Publication type:

Article

Synthesis and Cytotoxic Evaluation of Alkoxylated Chalcones.

Published in:

Molecules, 2014, v. 19, n. 11, p. 17256, doi. 10.3390/molecules191117256

By:

Xiao-Guang Bai;
Chang-Liang Xu;
Shuang-Shuang Zhao;
Hong-Wei He;
Yu-Cheng Wang;
Ju-Xian Wang

Publication type:

Article

Novel Cinnamic Acid Derivatives as Antioxidant and Anticancer Agents: Design, Synthesis and Modeling Studies.

Published in:

Molecules, 2014, v. 19, n. 7, p. 9655, doi. 10.3390/molecules19079655

By:

Pontiki, Eleni;
Hadjipavlou-Litina, Dimitra;
Litinas, Konstantinos;
Geromichalos, George

Publication type:

Article

Synthesis of Caffeic Acid Amides Bearing 2,3,4,5-Tetrahydrobenzo[ b][1,4]dioxocine Moieties and Their Biological Evaluation as Antitumor Agents.

Published in:

Molecules, 2014, v. 19, n. 6, p. 7269, doi. 10.3390/molecules19067269

By:

Ji-Wen Yuan;
Han-Yue Qiu;
Peng-Fei Wang;
Makawana, Jigar A.;
Yong-An Yang;
Fei Zhang;
Yong Yin;
Jie Lin;
Zhong-Chang Wang;
Hai-Liang Zhu

Publication type:

Article

Scalable and green process for the synthesis of anticancer drug lenalidomide.

Published in:

Chemistry of Heterocyclic Compounds, 2015, v. 51, n. 2, p. 133, doi. 10.1007/s10593-015-1670-0

By:

Ponomaryov, Yuri;
Krasikova, Valeria;
Lebedev, Anton;
Chernyak, Dmitri;
Varacheva, Larisa;
Chernobroviy, Alexandr

Publication type:

Article

Cyclopropanol intermediates in the synthesis of the C-C fragment of laulimalides.

Published in:

Russian Journal of Organic Chemistry, 2016, v. 52, n. 3, p. 355, doi. 10.1134/S1070428016030118

By:

Mineeva, I.

Publication type:

Article

SYNTHESIS AND ANTI-CANCER ACTIVITY OF NOVEL 3-ARYL THIOPHENE-2-CARBALDEHYDES AND THEIR ARYL/HETEROARYL CHALCONE DERIVATIVES.

Published in:

Rasayan Journal of Chemistry, 2016, v. 9, n. 1, p. 31

By:

Venkataramireddy, V.;
Shankaraiah, M.;
Rao, A. Tejeswara;
Kalyani, Ch.;
Narasu, M. Lakshmi;
Varala, Ravi;
Jayashree, A.

Publication type:

Article

Structure elucidation of 3-[1-(6-methoxy-2-naphtyl)ethyl]-6-(2,4-dichlorophenyl)-7H-1,2,4-triazolo[3,4-b]-1,3,4-thiadiazine, C23H18Cl2N4OS from synchrotron X-ray powder diffraction.

Published in:

Powder Diffraction, 2017, v. 32, n. 4, p. 271, doi. 10.1017/S0885715617001099

By:

Gündoğdu, Gülsüm;
Aytaç, Sevim Peri;
Müller, Melanie;
Tozkoparan, Birsen;
Kaynak, Filiz Betül

Publication type:

Article

Methyl gallate isolated from Spondias pinnata exhibits anticancer activity against human glioblastoma by induction of apoptosis and sustained extracellular signal-regulated kinase 1/2 activation.

Published in:

Pharmacognosy Magazine, 2015, v. 11, n. 42, p. 269, doi. 10.4103/0973-1296.153078

By:

Chaudhuri, Dipankar;
Ghate, Nikhil Baban;
Singh, Sudhir Shankar;
Mandal, Nripendranath

Publication type:

Article

A Concise and Practical Semisynthesis of Ecteinascidin 743 and (–)-Jorumycin.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 5, p. 975, doi. 10.1002/ejoc.201601409

By:

Xu, Shanghu;
Wang, Guan;
Zhu, Jinjin;
Shen, Chuang;
Yang, Zhezhou;
Yu, Jun;
Li, Zhong;
Lin, Tanghuan;
Sun, Xun;
Zhang, Fuli

Publication type:

Article

Improved Strategy for the Synthesis of the Anticancer Agent Culicinin D.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 28, p. 6341, doi. 10.1002/ejoc.201500872

By:

Stach, Michaela;
Weidkamp, Andreas J.;
Yang, Sung‐Hyun;
Hung, Kuo‐yuan;
Furkert, Daniel P.;
Harris, Paul W. R.;
Smaill, Jeff B.;
Patterson, Adam V.;
Brimble, Margaret A.

Publication type:

Article

Divergent and Concise Syntheses of Spiroisoxazolines: First Total Synthesis of 11-Deoxyfistularin-3.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 23, p. 5159, doi. 10.1002/ejoc.201500603

By:

Das, Prasanta;
Hamme II, Ashton T.

Publication type:

Article

Diversity-Oriented Synthesis of Calothrixins and Ellipticines.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 31, p. 6953, doi. 10.1002/ejoc.201402837

By:

Dethe, Dattatraya H.;
Murhade, Ganesh M.

Publication type:

Article

Overexpression of tryptophan decarboxylase and strictosidine synthase enhanced terpenoid indole alkaloid pathway activity and antineoplastic vinblastine biosynthesis in Catharanthus roseus.

Published in:

Protoplasma, 2018, v. 255, n. 5, p. 1281, doi. 10.1007/s00709-018-1233-1

By:

Sharma, Abhishek;
Verma, Priyanka;
Mathur, Archana;
Mathur, Ajay Kumar

Publication type:

Article

Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy.

Published in:

British Journal of Cancer, 2015, v. 112, n. 5, p. 832, doi. 10.1038/bjc.2015.17

By:

Tan, Q;
Joshua, A M;
Saggar, J K;
Yu, M;
Wang, M;
Kanga, N;
Zhang, J Y;
Chen, X;
Wouters, B G;
Tannock, I F

Publication type:

Article

MDM2 is an important prognostic and predictive factor for platin-pemetrexed therapy in malignant pleural mesotheliomas and deregulation of P14/ARF (encoded by CDKN2A) seems to contribute to an MDM2-driven inactivation of P53.

Published in:

British Journal of Cancer, 2015, v. 112, n. 5, p. 883, doi. 10.1038/bjc.2015.27

By:

Walter, R F H;
Mairinger, F D;
Ting, S;
Vollbrecht, C;
Mairinger, T;
Theegarten, D;
Christoph, D C;
Schmid, K W;
Wohlschlaeger, J

Publication type:

Article

Synthesis and Characterization of trans-Dichlorotetrakis(imidazole)cobalt(III) Chloride: A New Cobalt(III) Coordination Complex with Potential Prodrug Properties.

Published in:

Bioinorganic Chemistry & Applications, 2018, p. 1, doi. 10.1155/2018/4560757

By:

Hart, Kaila F.;
Joe, Natalie S.;
Miller, Rebecca M.;
Nash, Hannah P.;
Blake, David J.;
Morris, Aimee M.

Publication type:

Article

Synthesis and Cell Death Mechanism of a Militarin Derivative.

Published in:

Bulletin of the Korean Chemical Society, 2016, v. 37, n. 3, p. 287, doi. 10.1002/bkcs.10667

By:

Chen, Fei;
Yoon, Deok Hyo;
Reddy, Dinneswara;
Han, Changwoo;
Choi, Sunga;
Cho, Jae Youl;
Sung, Gi-Ho;
Hwang, Ki-Chul;
Kim, Tae Woong;
Park, Haeil

Publication type:

Article

A20 suppresses hepatocellular carcinoma proliferation and metastasis through inhibition of Twist1 expression.

Published in:

Molecular Cancer, 2015, v. 14, n. 1, p. 1, doi. 10.1186/s12943-015-0454-6

By:

Haiyang Chen;
Liang Hu;
Zaili Luo;
Jian Zhang;
Cunzhen Zhang;
Bijun Qiu;
Liwei Dong;
Yexiong Tan;
Jin Ding;
Shanhua Tang;
Feng Shen;
Zhong Li;
Hongyang Wang

Publication type:

Article

Synthesis, Characterization, and in vitro Cytotoxicity of Gold(I) Complexes of 2-(Diphenylphosphanyl)ethylamine and Dithiocarbamates.

Published in:

Zeitschrift für Anorganische und Allgemeine Chemie, 2016, v. 642, n. 24, p. 1454, doi. 10.1002/zaac.201600278

By:

Sulaiman, Adam A. A.;
Altaf, Muhammad;
Isab, Anvarhusein A.;
Alawad, Abdullah;
Altuwaijri, Saleh;
Ahmad, Saeed

Publication type:

Article

Increased heterologous production of the antitumoral polyketide mithramycin A by engineered Streptomyces lividans TK24 strains.

Published in:

Applied Microbiology & Biotechnology, 2018, v. 102, n. 2, p. 857, doi. 10.1007/s00253-017-8642-5

By:

Novakova, Renata;
Núñez, Luz Elena;
Homerova, Dagmar;
Knirschova, Renata;
Feckova, Lubomira;
Rezuchova, Bronislava;
Sevcikova, Beatrica;
Menéndez, Nuria;
Morís, Francisco;
Cortés, Jesús;
Kormanec, Jan

Publication type:

Article

Current understanding of synergistic interplay of chitosan nanoparticles and anticancer drugs: merits and challenges.

Published in:

Applied Microbiology & Biotechnology, 2015, v. 99, n. 5, p. 2055, doi. 10.1007/s00253-015-6384-9

By:

Kandra, Prameela;
Kalangi, Hemalatha

Publication type:

Article

Aryl sulfonate based anticancer alkylating agents.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2018, v. 31, p. 1081

By:

Sheikh, Hamdullah Khadim;
Arshad, Tanzila;
Kanwal, Ghazala

Publication type:

Article

Evaluation of cytotoxic and antiviral activities of aqueous leaves extracts of different plants against foot and mouth disease virus infection in farming animals.

Published in:

Pakistan Journal of Pharmaceutical Sciences, 2017, v. 30, n. 6, p. 2167

By:

Younus, Ishrat;
Ashraf, Muhammad;
Fatima, Anab;
Altaf, Imran;
Javeed, Aqeel

Publication type:

Article

A Set of Activity-Based Probes to Visualize Human (Immuno)proteasome Activities.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 13, p. 4199, doi. 10.1002/anie.201509092

By:

de Bruin, Gerjan;
Xin, Bo Tao;
Kraus, Marianne;
van der Stelt, Mario;
van der Marel, Gijsbert A.;
Kisselev, Alexei F.;
Driessen, Christoph;
Florea, Bogdan I.;
Overkleeft, Herman S.

Publication type:

Article

Use of a 'Catalytic' Cosolvent, N, N-Dimethyl Octanamide, Allows the Flow Synthesis of Imatinib with no Solvent Switch.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 7, p. 2531, doi. 10.1002/anie.201509922

By:

Yang, Jeffrey C.;
Niu, Dawen;
Karsten, Bram P.;
Lima, Fabio;
Buchwald, Stephen L.

Publication type:

Article