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Title

A new ocotillol-type ginsenoside from American ginseng berry.

Authors

Jin, Yinping; Qu, Zhengyi; Pang, Shifeng; Li, Zheng; Wang, Yingping; Zhang, Hao

Abstract

A new ocotillol-type ginsenoside, named pseudoginsenoside F12 (1), was isolated from American ginseng berry, whose structure was elucidated as 6-O-[α-L-2,3-epoxy-rhamnopyranosyl-(1-2)-β-D-glucopyranosyl]-dammar-20S,24R-epoxy-3β, 6α,12β,25-tetraol. In addition, the known alkaloids β-carboline-1-carboxylic acid (2) and anoectochine (3) were isolated for the first time from the Araliaceae family. The new compound 1 was evaluated for cytotoxicity against MDA-MB-231 breast cancer cell line.

Subjects

AMERICAN ginseng; INDOLE alkaloids; GINSENOSIDES; CYTOTOXINS; ARALIACEAE

Publication

Natural Product Research, 2025, Vol 39, Issue 1, p73

ISSN

1478-6419

Publication type

Academic Journal

DOI

10.1080/14786419.2023.2252566