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Title

Isopimarane-type diterpenoids from Croton laevigatus.

Authors

Li, Man-Yu; Han, Zheng-Zhi; Liu, Li-Fang; Wu, Xiao-Zhen; Huang, Wen-Jun; Wang, Kai; Yang, Fan; Yuan, Cheng-Shan

Abstract

A new isopimarane-type diterpenoid, crolaevinoid A, along with four known analogues was isolated from the twigs and leaves of Croton laevigatus. The structures of the isolated compounds were established on the basis of NMR and MS spectroscopic analyses. The isolated compounds were examined the antibacterial activities. Unfortunately, the compounds showed no antibacterial activity against Micrococcus luteus, Methicillin-resistant Staphylococcus aureus, Aeromonas hydrophila, Klebsiella pneumoniae ssp pneumoniae, Acinetobacter Baumanii, and Escherichia coli.

Subjects

DITERPENES; AEROMONAS hydrophila; MICROCOCCUS luteus; METHICILLIN-resistant staphylococcus aureus; KLEBSIELLA pneumoniae

Publication

Natural Product Research, 2020, Vol 34, Issue 20, p2976

ISSN

1478-6419

Publication type

Academic Journal

DOI

10.1080/14786419.2019.1596096

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