Title: A new sesquiterpenoid glycoside from Saussurea involucrata.
Authors: Qi, Shizhou; Yang, Yiren; Xian, Xiaoyan; Li, Xianzhe; Gao, Huiyuan
Abstract: Saussurea involucrata, known for the abundant bioactive components, is a precious traditional Chinese medicine. In this study, a novel guaiane sesquiterpenoid glycoside named (1R, 5R, 6R, 7R, 8S, 11S)-11, 13-dihydrodehydrocostuslactone-8-O-6'-2''(E)-butenoyl-β-D-glucopyranoside (1), together with seven known compounds (2–8) were isolated from the dried aerial part of S. involucrata. Their structures were elucidated by spectroscopic and physico-chemical analyses. The antioxidant and anti-inflammatory activities of compound 1 were investigated. And compound 1 showed weak radical scavenging activity and low inhibitory activity on nitric oxide (NO) production.
Subjects: SAUSSUREA; CHINESE medicine; NITRIC oxide
Publication: Natural Product Research, 2020, Vol 34, Issue 7, p943
ISSN: 1478-6419
Publication type: Academic Journal
DOI: 10.1080/14786419.2018.1543683

A new sesquiterpenoid glycoside from Saussurea involucrata.

Qi, Shizhou; Yang, Yiren; Xian, Xiaoyan; Li, Xianzhe; Gao, Huiyuan