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Title

(3R,4S)-isostreptenol III from Penicillium purpurogenum MM.

Authors

Shaaban, Mohamed

Abstract

In continuation of the search for new compounds from the terrestrial fungus Penicillium purpurogenum MM, (3R,4S)-isostreptenol III (1), a further new natural compound is reported. The chemical structure of 1 was confirmed by extensive 1D and 2D NMR and ESI HR mass measurements, and by comparison with literature data. The absolute configuration was determined by ab initio calculations of ECD, ORD, and NMR data. The antimicrobial and cytotoxic activities of the crude extract and 1 were reported using a set of microorganisms and by the brine shrimp assay, respectively.

Subjects

PENICILLIUM; ARTEMIA; CHEMICAL structure; MASS measurement

Publication

Natural Product Research, 2020, Vol 34, Issue 7, p1032

ISSN

1478-6419

Publication type

Academic Journal

DOI

10.1080/14786419.2018.1538997