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- Title
A new aliphatic ester of hydroxysalicylic acid from fermented Carica papaya L. preparation with a potential hair growth stimulating activity.
- Authors
Ashour, Ahmed; Amen, Yhiya; Nakagawa, Toshinori; Niwa, Yasuharu; Mira, Amira; Ohnuki, Koichiro; Murakami, Shinki; Imao, Mitsuko; Shimizu, Kuniyoshi
- Abstract
An aliphatic ester of hydroxysalicylic acid (6), reported for the first time from a natural source in addition to five known compounds were isolated from the fermented Carica papaya L. preparation, a commercialized functional food. The known compounds were identified as 5-hydroxymethylfurfuraldehyde (1), trans-caffeic acid (2), butyl 4-hydroxybenzoate (butylparaben) (3), lycopene (4), benzyl isothiocyanate (5). Compounds 1 and 3 were reported for the first time from Papaya fruits through this study. The new compound showed a moderate antioxidant activity and a potent hair growth stimulating activity in vitro.
- Subjects
PAPAYA; HAIR growth; HAIR care products; MINOXIDIL; ESTERS; FUNCTIONAL foods
- Publication
Natural Product Research, 2020, Vol 34, Issue 12, p1750
- ISSN
1478-6419
- Publication type
Academic Journal
- DOI
10.1080/14786419.2018.1530231